Quality control and safety management are two very important contents in building construction project management.Once the construction quality is not up to standard or a safety accident occurs,the economic benefits o...Quality control and safety management are two very important contents in building construction project management.Once the construction quality is not up to standard or a safety accident occurs,the economic benefits of the project will be severely impacted.However,there are still some problems in the quality and safety management of the project.In this paper the problems in construction quality control and safety management are analyzed,and effective countermeasures are put forward,in hopes to help improve construction quality and safety.展开更多
Following economic development and improved living standards in China in recent years, there has been a growing demand for foreign durable goods and household electrical appliances and motor cycles. However, some impo...Following economic development and improved living standards in China in recent years, there has been a growing demand for foreign durable goods and household electrical appliances and motor cycles. However, some imported consumer goods have serious safety and quality defects.展开更多
An effective quality control system is the key to ensuring the quality, safety and efficacy of traditional Chinese medicines(TCMs). However, the current quality standard research lacks top-level design and systematic ...An effective quality control system is the key to ensuring the quality, safety and efficacy of traditional Chinese medicines(TCMs). However, the current quality standard research lacks top-level design and systematic design,mostly based on specific technologies or evaluation methods. To resolve the challenges and questions of quality control of TCMs, a brand-new quality standard system, named "iVarious", was proposed. The system comprises eight elements in a modular format. Meaning of every element was specifically illustrated via corresponding research instances. Furthermore, frankincense study was taken as an example for demonstrating standards and research process, based on the "i Various" system. This system highlighted a holistic strategy for effectiveness,security, integrity and systematization of quality and safety control standards of TCMs. The establishment of"i Various" integrates multi-disciplinary technologies and progressive methods, basis elements and key points of standard construction. The system provides a novel idea and technological demonstration for regulation establishment of TCMs quality standards.展开更多
In the development process of the society nowadays,electrical engineering has been widely used with remarkable results,but there are still some problems in the course of actual management,which requires effective tech...In the development process of the society nowadays,electrical engineering has been widely used with remarkable results,but there are still some problems in the course of actual management,which requires effective technical measures to control the quality in electrical engineering and the enhancement of safety management work.Therefore,in order to better ensure safety management requirements in electrical engineering and strengthen related trainings and thus better carried out safety management and quality control to meet respective requirements in the real world,in this paper,a brief analysis is conducted in quality control and safety management in electrical engineering.展开更多
In order to solve such problems as lack of dynamic evaluation system in evaluation of quality and safety trust of dairy products,and weak awareness of prevention,it is necessary to introduce the statistical process co...In order to solve such problems as lack of dynamic evaluation system in evaluation of quality and safety trust of dairy products,and weak awareness of prevention,it is necessary to introduce the statistical process control into the quality and safety trust evaluation system of dairy products,and establish quality and safety trust early warning model for dairy products,so as to determine the control limit of control chart and carry out early warning according to eight criteria. According to the empirical results,the statistical process control is helpful for finding the hidden process risks and providing the necessary basis for enterprises taking positive measures to raise the confidence of consumers.展开更多
Adoptive cell therapy using chimeric antigen receptor T (CAR-T) cells, which is a promising cancer immunotherapy strategy, has been developing very rapidly in recent years. CAR-T cells are genetically modified T cells...Adoptive cell therapy using chimeric antigen receptor T (CAR-T) cells, which is a promising cancer immunotherapy strategy, has been developing very rapidly in recent years. CAR-T cells are genetically modified T cells that can specifically recognize tumor specific antigens on the surface of tumor cells, and then effectively kill tumor cells. At present, exciting results are being achieved in clinical applications of CAR-T cells for patients with hematological malignancies. The research and development of CAR-T cells for various targets and for the treatment of solid tumors have become a hot topic worldwide, so an increasing number of investigational new drug applications (INDAs) and new drug applications (NDAs) of CAR-T cell products are expected to be submitted in future. The quality control and nonclinical research of these products are of great significance in ensuring the safety and effectiveness of these products;however, they also present great challenges and difficulties. This article discusses the general principles of and key issues regarding the quality control and nonclinical research of CAR-T cell products based on their product characteristics and on relevant guidelines for gene and cell therapy products.展开更多
In the research, harmful substances to oolong in Anxi were introduced and production environment, agricultural residual, heavy metal and rare earth ele-ments of oolong in Anxi were analyzed. Furthermore, the factors i...In the research, harmful substances to oolong in Anxi were introduced and production environment, agricultural residual, heavy metal and rare earth ele-ments of oolong in Anxi were analyzed. Furthermore, the factors influencing oolong quality were explored, and the control measures for guaranteeing oolong safety were proposed.展开更多
In the process of blasting excavation, stress wave propagation and gas expansion can basically induce damage to surrounding rocks, which is detrimental to rock mass integrity and engineering safety. In this case, eval...In the process of blasting excavation, stress wave propagation and gas expansion can basically induce damage to surrounding rocks, which is detrimental to rock mass integrity and engineering safety. In this case, evaluation and control of blast-induced effects are essential to the safety of nearby buildings and integrity of bedrock in blasting field. In Fangchenggang nuclear power station of China, the drill-and- blast method was employed for bedrock excavation. In order to reduce the blast-induced damage zone, the wave propagation and associated damage to rock mass should be carefully investigated. In this paper, the wave propagation regressively obtained from field monitoring data was presented based on empirical formula (e.g. Sadovsloj formula). The relationship between the peak particle velocity (PPV) at a distance of 30 m away from the charge hole and charge per delay in blast design was derived. Meanwhile, the acoustic tests before and after blasting were conducted to determine the damage depth of rock mass. The charge per delay in blast design was then calibrated based on the blast-induced wave propagation regularity. The results showed that a satisfactory effect was achieved on blast-induced damage control of rock mass. This could be helpful to rock damage control in similar blasting projects.展开更多
In recent years, the work of quality supervision and production safety of aquatic products in Nanjing City has been carried out rapidly, and the system of "origin exit, market access, sign traceability, real-time...In recent years, the work of quality supervision and production safety of aquatic products in Nanjing City has been carried out rapidly, and the system of "origin exit, market access, sign traceability, real-time monitoring" has been basically formed, initially realizing the whole-process monitoring on the quality safety of aquatic products from "pond to table". We take the current situation of quality supervision and production safety of aquatic products in Nanjing City as the study object, take the basic work of supervision on aquatic products in Nanjing City and advancing both in scope and in depth as breakthrough point, to sum up the results achieved in the work of quality supervision and production safety of aquatic products in Nanjing City in recent years; make initial exploration and research, in order to consolidate the existing achievements, and further enhance the level of supervision on quality safety of aquatic products in Nanjing City.展开更多
文摘Quality control and safety management are two very important contents in building construction project management.Once the construction quality is not up to standard or a safety accident occurs,the economic benefits of the project will be severely impacted.However,there are still some problems in the quality and safety management of the project.In this paper the problems in construction quality control and safety management are analyzed,and effective countermeasures are put forward,in hopes to help improve construction quality and safety.
文摘Following economic development and improved living standards in China in recent years, there has been a growing demand for foreign durable goods and household electrical appliances and motor cycles. However, some imported consumer goods have serious safety and quality defects.
基金financial support from National Major Scientific and Technological Special Project for "Significant New Drugs Development" (2014ZX09304307-002)Youth Development Research Foundation of NIFDC (2013WA8)the National Natural Foundation of China (81303214)
文摘An effective quality control system is the key to ensuring the quality, safety and efficacy of traditional Chinese medicines(TCMs). However, the current quality standard research lacks top-level design and systematic design,mostly based on specific technologies or evaluation methods. To resolve the challenges and questions of quality control of TCMs, a brand-new quality standard system, named "iVarious", was proposed. The system comprises eight elements in a modular format. Meaning of every element was specifically illustrated via corresponding research instances. Furthermore, frankincense study was taken as an example for demonstrating standards and research process, based on the "i Various" system. This system highlighted a holistic strategy for effectiveness,security, integrity and systematization of quality and safety control standards of TCMs. The establishment of"i Various" integrates multi-disciplinary technologies and progressive methods, basis elements and key points of standard construction. The system provides a novel idea and technological demonstration for regulation establishment of TCMs quality standards.
文摘In the development process of the society nowadays,electrical engineering has been widely used with remarkable results,but there are still some problems in the course of actual management,which requires effective technical measures to control the quality in electrical engineering and the enhancement of safety management work.Therefore,in order to better ensure safety management requirements in electrical engineering and strengthen related trainings and thus better carried out safety management and quality control to meet respective requirements in the real world,in this paper,a brief analysis is conducted in quality control and safety management in electrical engineering.
基金Supported by Program of Chongqing University of Arts and Sciences(Z2014JG14)Young Scholar Project of Humanities and Social Science Foundation of Ministry of Education(15XJC790002)
文摘In order to solve such problems as lack of dynamic evaluation system in evaluation of quality and safety trust of dairy products,and weak awareness of prevention,it is necessary to introduce the statistical process control into the quality and safety trust evaluation system of dairy products,and establish quality and safety trust early warning model for dairy products,so as to determine the control limit of control chart and carry out early warning according to eight criteria. According to the empirical results,the statistical process control is helpful for finding the hidden process risks and providing the necessary basis for enterprises taking positive measures to raise the confidence of consumers.
文摘Adoptive cell therapy using chimeric antigen receptor T (CAR-T) cells, which is a promising cancer immunotherapy strategy, has been developing very rapidly in recent years. CAR-T cells are genetically modified T cells that can specifically recognize tumor specific antigens on the surface of tumor cells, and then effectively kill tumor cells. At present, exciting results are being achieved in clinical applications of CAR-T cells for patients with hematological malignancies. The research and development of CAR-T cells for various targets and for the treatment of solid tumors have become a hot topic worldwide, so an increasing number of investigational new drug applications (INDAs) and new drug applications (NDAs) of CAR-T cell products are expected to be submitted in future. The quality control and nonclinical research of these products are of great significance in ensuring the safety and effectiveness of these products;however, they also present great challenges and difficulties. This article discusses the general principles of and key issues regarding the quality control and nonclinical research of CAR-T cell products based on their product characteristics and on relevant guidelines for gene and cell therapy products.
基金Foundation for Young Talents of Fujian Entry-Exit Inspection and Quarantine Bureau(FK2012-47)~~
文摘In the research, harmful substances to oolong in Anxi were introduced and production environment, agricultural residual, heavy metal and rare earth ele-ments of oolong in Anxi were analyzed. Furthermore, the factors influencing oolong quality were explored, and the control measures for guaranteeing oolong safety were proposed.
基金supported by the Key Program of National Natural Science Foundation of China(Grant No.51439008)National Natural Science Foundation of China(Grant Nos.41572307 and51779248)National Natural Science Funds for Distinguished Young Scholar of China(Grant No.41525009)
文摘In the process of blasting excavation, stress wave propagation and gas expansion can basically induce damage to surrounding rocks, which is detrimental to rock mass integrity and engineering safety. In this case, evaluation and control of blast-induced effects are essential to the safety of nearby buildings and integrity of bedrock in blasting field. In Fangchenggang nuclear power station of China, the drill-and- blast method was employed for bedrock excavation. In order to reduce the blast-induced damage zone, the wave propagation and associated damage to rock mass should be carefully investigated. In this paper, the wave propagation regressively obtained from field monitoring data was presented based on empirical formula (e.g. Sadovsloj formula). The relationship between the peak particle velocity (PPV) at a distance of 30 m away from the charge hole and charge per delay in blast design was derived. Meanwhile, the acoustic tests before and after blasting were conducted to determine the damage depth of rock mass. The charge per delay in blast design was then calibrated based on the blast-induced wave propagation regularity. The results showed that a satisfactory effect was achieved on blast-induced damage control of rock mass. This could be helpful to rock damage control in similar blasting projects.
基金Supported by Nanjing Science and Technology Plan Project (2008701S)
文摘In recent years, the work of quality supervision and production safety of aquatic products in Nanjing City has been carried out rapidly, and the system of "origin exit, market access, sign traceability, real-time monitoring" has been basically formed, initially realizing the whole-process monitoring on the quality safety of aquatic products from "pond to table". We take the current situation of quality supervision and production safety of aquatic products in Nanjing City as the study object, take the basic work of supervision on aquatic products in Nanjing City and advancing both in scope and in depth as breakthrough point, to sum up the results achieved in the work of quality supervision and production safety of aquatic products in Nanjing City in recent years; make initial exploration and research, in order to consolidate the existing achievements, and further enhance the level of supervision on quality safety of aquatic products in Nanjing City.