Objectives: Research on effects of comorbidities disease on anticoagulation overdose in patients receiving anticoagulant therapy with vitamin K antagonists anticoagulant (VKAs) drugs at HaiPhong-VinhBao International ...Objectives: Research on effects of comorbidities disease on anticoagulation overdose in patients receiving anticoagulant therapy with vitamin K antagonists anticoagulant (VKAs) drugs at HaiPhong-VinhBao International General Hospital. Methods: Description and Prospective study. Research on 79 patients receiving anticoagulant therapy with VKAs who have an INR testing index of more than anticoagulation dose with VKAs and check INR every 4 weeks. Results: The average research age is 65.65 ± 12.17 years [33: 85], most of the elderly group. The Male group is lower than the female group (p > 0.05). Patients with hemorrhage signs account for 22.8%. The INR testing index has an average value is 5.88 ± 3.0 [3.02 - 23.95];The group of INR > 5 level is a higher risk of bleeding than the group of INR ≤ 5 levels, there is statistical difference (p Conclusion: All most patients with anticoagulation overdose are in the elderly group. The group with INR > 5 levels has a higher risk of bleeding than the group with INR ≤ 5 levels, it’s the statistical significance (p 1 but p > 0.05);Patients used VKAs drugs on the background of kidney failure or arthritis pathology are the cause of the increased risk of bleeding, it’s statistical significance (p < 0.05).展开更多
Antipatelet therapy paly a vital role in preventing atherothrombotic events in patients with coronary artery disease and in those underging revascularization procedures.How,the therapy may occur at the expense of incr...Antipatelet therapy paly a vital role in preventing atherothrombotic events in patients with coronary artery disease and in those underging revascularization procedures.How,the therapy may occur at the expense of increase risk of bleeding.With a stronger antiplatelet treatment in clinical application,the risk of bleeding causedby antiplatelet agents has become a new and展开更多
Microparticles(MPs) are small anucleoid phospholipid vesicles shed from platelets,erythrocytes,leukocytes and endothelial cells.MPs contains a membrane skeletion and are defined by their size and expression on their s...Microparticles(MPs) are small anucleoid phospholipid vesicles shed from platelets,erythrocytes,leukocytes and endothelial cells.MPs contains a membrane skeletion and are defined by their size and expression on their surface of antigens specific of parental cells.The diameter of MPs are from 0.1 to 1 m.展开更多
Adenotonsillectomy is one of the most common surgical procedures performed by otolaryngologists.It is vital that surgeons are aware of the risks in performing this surgery especially during the COVID-19 pandemic and i...Adenotonsillectomy is one of the most common surgical procedures performed by otolaryngologists.It is vital that surgeons are aware of the risks in performing this surgery especially during the COVID-19 pandemic and in children with hematologic disorders.In this review we describe common hematologic disorders often noted in pediatric patients undergoing this procedure,as well as proper screening and management of these patients.In addition,we also address the impact of the COVID-19 pandemic and some measures to help mitigate the risks of this procedure during this time.展开更多
文摘Objectives: Research on effects of comorbidities disease on anticoagulation overdose in patients receiving anticoagulant therapy with vitamin K antagonists anticoagulant (VKAs) drugs at HaiPhong-VinhBao International General Hospital. Methods: Description and Prospective study. Research on 79 patients receiving anticoagulant therapy with VKAs who have an INR testing index of more than anticoagulation dose with VKAs and check INR every 4 weeks. Results: The average research age is 65.65 ± 12.17 years [33: 85], most of the elderly group. The Male group is lower than the female group (p > 0.05). Patients with hemorrhage signs account for 22.8%. The INR testing index has an average value is 5.88 ± 3.0 [3.02 - 23.95];The group of INR > 5 level is a higher risk of bleeding than the group of INR ≤ 5 levels, there is statistical difference (p Conclusion: All most patients with anticoagulation overdose are in the elderly group. The group with INR > 5 levels has a higher risk of bleeding than the group with INR ≤ 5 levels, it’s the statistical significance (p 1 but p > 0.05);Patients used VKAs drugs on the background of kidney failure or arthritis pathology are the cause of the increased risk of bleeding, it’s statistical significance (p < 0.05).
文摘Antipatelet therapy paly a vital role in preventing atherothrombotic events in patients with coronary artery disease and in those underging revascularization procedures.How,the therapy may occur at the expense of increase risk of bleeding.With a stronger antiplatelet treatment in clinical application,the risk of bleeding causedby antiplatelet agents has become a new and
文摘Microparticles(MPs) are small anucleoid phospholipid vesicles shed from platelets,erythrocytes,leukocytes and endothelial cells.MPs contains a membrane skeletion and are defined by their size and expression on their surface of antigens specific of parental cells.The diameter of MPs are from 0.1 to 1 m.
文摘Adenotonsillectomy is one of the most common surgical procedures performed by otolaryngologists.It is vital that surgeons are aware of the risks in performing this surgery especially during the COVID-19 pandemic and in children with hematologic disorders.In this review we describe common hematologic disorders often noted in pediatric patients undergoing this procedure,as well as proper screening and management of these patients.In addition,we also address the impact of the COVID-19 pandemic and some measures to help mitigate the risks of this procedure during this time.
