Objective:To evaluate the effect and efficiency of ear tip bloodletting combined with Xianfang Huoming Yin(XFH)in the treatment of early-stage wheals.Methods:70 patients with early-stage wheals admitted from September...Objective:To evaluate the effect and efficiency of ear tip bloodletting combined with Xianfang Huoming Yin(XFH)in the treatment of early-stage wheals.Methods:70 patients with early-stage wheals admitted from September 2020 to September 2022 were divided into two groups by randomized numerical table method,with 35 cases/group.Both groups received conventional treatment,the control group combined with XFH,and the observation group combined with ear tip bloodletting therapy and XFH.Conscious symptom scores,ocular indexes,therapeutic effects,and sleep quality between the two groups were compared.Results:After the treatment,the patients in the observation group had lower self-awareness symptom scores and sleep quality scores as compared to those in the control group;the diameter of the mass in the observation group was smaller than that of the control group after treatment;the average tear film rupture time and the time taken for the first non-contact tear film to rupture were longer in the observation group than those in the control group;the total effective rate of the treatment in the observation group was higher than that of the control group(P<0.05).Conclusion:Ear tip bloodletting combined with XFH was ideal for the treatment of early-stage wheals and has a high effective rate.展开更多
Compared to other crops,maize production demands relatively high temperatures.However,temperatures exceeding 35℃lead to adverse effects on maize yield.High temperatures(≥35℃)are consistently experienced by summer m...Compared to other crops,maize production demands relatively high temperatures.However,temperatures exceeding 35℃lead to adverse effects on maize yield.High temperatures(≥35℃)are consistently experienced by summer maize during its reproductive growth stage in the North China Plain,which is likely to cause irreversible crop damage.This study investigated the effects of elevating temperature(ET)treatment on the yield component of summer maize,beginning at the 9th unfolding leaf stage and ending at the tasseling stage.Results demonstrated that continuous ET led to a decrease in the elongation rate and activity of silks and an elongated interval between anthesis and silking stages,and eventually decreased grain number at ear tip and reduced yield.Although continuous ET before tasseling damaged the anther structure,reduced pollen activity,delayed the start of the pollen shedding stage,and shortened the pollen shedding time,it was inferred,based on phenotypical and physiological traits,that continuous ET after the 9th unfolding leaf stage influenced ears and therefore may have more significant impacts.Overall,when maize plants were exposed to ET treatment in the ear reproductive development stage,the growth of ears and tassels was blocked,which increased the occurrence of barren ear tips and led to large yield losses.展开更多
The aim of this paper is to study the inheritance pattern of ear tip-barrenness trait in maize (Zea mays L.). Ear tipbarrenness trait in maize can be classified into two types, tip-barren and tip-barrenless. Two inb...The aim of this paper is to study the inheritance pattern of ear tip-barrenness trait in maize (Zea mays L.). Ear tipbarrenness trait in maize can be classified into two types, tip-barren and tip-barrenless. Two inbred lines, lx01-3 (tipbarrenless type), wx04-1 (tip-barren type), and their F1, F2, BC1, BC2 generations were analyzed on their ear tip-barrenness types. Results showed that F1 was tip-barren type; the ratio of tip-barren type versus tip-barrenless type followed a 12.78: 1 ratio in F2 segregation population and a 2.75:1 ratio in BC1. Z2 test indicated that the trait of ear tip-barrenness type followed an inheritance pattern of 2 duplicate dominant genes. SPSS analysis indicated that the trait of ear tip-barrenness length is of abnormal distribution. Above results mean that: (1) The trait of maize ear tip-barrenness type is controlled by 2 duplicate dominant genes; tip-barren type is dominant over tip-barrenless type; (2) the trait of tip-barrenness length is a quantitative character controlled by polygene with major genes expected.展开更多
目的 探讨经皮门静脉穿刺改良经颈内静脉肝内门体分流术(TIPS)较常规TIPS方法的优越性及临床疗效.方法 回顾性分析空军总医院2009年3月~2011年9月采用TIPS技术治疗门脉高压急性上消化道出血患者36例,其中15例采用常规TIPS技术,21例...目的 探讨经皮门静脉穿刺改良经颈内静脉肝内门体分流术(TIPS)较常规TIPS方法的优越性及临床疗效.方法 回顾性分析空军总医院2009年3月~2011年9月采用TIPS技术治疗门脉高压急性上消化道出血患者36例,其中15例采用常规TIPS技术,21例采用经皮肝穿刺门静脉造影改良TIPS技术.结果 改良TIPS组与常规TIPS组相比,手术时间显著缩短(183.69±56.77 vs 140.32±43.56)、手术开始至胃冠状静脉封堵时间显著缩短(130.81±66.39 vs 12.53±13.18)、穿刺针数显著减少(7.57±3.14 vs 4.16±2.73)、改良TIPS组手术成功率100%,常规TIPS组手术成功率80%,两组治疗均可显著降低门静脉压力.结论 超声引导下经皮门静脉穿刺造影,可标识定位指导TIPS操作,并可在第一时间封堵胃冠状静脉出血,提高了TIPS穿刺的准确性和安全性,可行性优于常规TIPS操作方法.展开更多
Background and Aim:Gastric varices are associated with high mortality.There have been conflicting reports on whether endoscopic treatment with cyanoacrylate or the placement of a transjugular intrahepatic portosystemi...Background and Aim:Gastric varices are associated with high mortality.There have been conflicting reports on whether endoscopic treatment with cyanoacrylate or the placement of a transjugular intrahepatic portosystemic shunt(TIPS)is more effective in the treatment of gastric varices.We compared the outcomes of patients treated with cyanoacrylate glue or TIPS for the management of acute gastric variceal bleeding.Methods:The study was designed as a retrospective cohort analysis of patients undergoing either TIPS or endoscopic treatment with cyanoacrylate for acute gastric variceal bleeding at our institution from 2001 to 2011.Primary compared to studied between the two treatment modalities were the short-term treatment outcomes,including re-bleeding within 30 days,length of hospital stay and in-hospital mortality.Kaplan-Meier survival analysis was performed to assess factors associated with in-hospital mortality.Results:A total of 169 patients were included in the analysis.The TIPS arm contained 140 patients and the cyanoacrylate arm contained 29 patients.There was no evidence to suggest any significant differences in demographics or disease severity.There were no differences between the TIPS arm and the cyanoacrylate armtwo groups in treatment outcomes including re-bleeding within 30 days(17.4%vs.17.2%;P=0.98),median length of stay in the hospital(4.5 days vs.6.0 days;P紏0.35)or in-hospital mortality(9.0%vs.11.1%;P=0.74).In-hospital mortality was evaluated for 149 patients and lower albumin(P=0.015),higher MELD score(P<0.001),higher CTP score(P=0.005)and bleeding(P=0.008)were all significantly associated with in-hospital death.Conclusion:These findings suggest that both treatments are equally effective.Cyanoacrylate offers a safe,effective alternative to TIPS for gastric varices,and physician may choose the best therapy for each patient,factoring in the availability of TIPS or cyanoacrylate,the individual patient’s presentation,and cost.展开更多
AIM: To identify all cases of bacteremia and suspected endotipsitis after Transjugular intrahepatic portosystemic shunting (TIPS) at our institution and to determine risk factors for their occurrence. METHODS: We retr...AIM: To identify all cases of bacteremia and suspected endotipsitis after Transjugular intrahepatic portosystemic shunting (TIPS) at our institution and to determine risk factors for their occurrence. METHODS: We retrospectively reviewed records of all patients who underwent TIPS in our institution between 1996 and 2009. Data included: indications for TIPS, underlying liver disease, demographics, positive blood cultures after TIPS, microbiological characteristics, treat- ment and outcome. RESULTS: 49 men and 47 women were included with a mean age of 55.8 years (range 15-84). Indications for TIPS included variceal bleeding, refractory ascites,hydrothorax and hepatorenal syndrome. Positive blood cultures after TIPS were found in 39/96 (40%) patients at various time intervals following the procedure. Seven patients had persistent bacteremia fitting the definition of endotipsitis. Staphylococcus species grew in 66% of the positive cultures, Candida and enterococci species in 15% each of the isolates, and 3% cultures grew other species. Multi-variate regression analysis identified 4 variables: hypothyroidism, HCV, prophylactic use of an- tibiotics and the procedure duration as independent risk factors for positive blood cultures following TIPS (P < 0.0006, 0.005, 0.001, 0.0003, respectively). Prophylactic use of antibiotics before the procedure was associated with a decreased risk for bacteremia, preventing mainly early infections, occurring within 120 d of the procedure. CONCLUSION: Bacteremia is common following TIPS. Risk factors associated with bacteremia include failure to use prophylactic antibiotics, hypothyroidism, HCV and a long procedure. Our results strongly support the use of prophylaxis as a means to decrease early post TIPS infections.展开更多
Objective To explore the safety and efficacy of transjugular intrahepatic portosystemic shunt(TIPS)in the treatment of esophago-gastric variceal bleeding(EGVB)complicated with cavernous transformation of portal vein(C...Objective To explore the safety and efficacy of transjugular intrahepatic portosystemic shunt(TIPS)in the treatment of esophago-gastric variceal bleeding(EGVB)complicated with cavernous transformation of portal vein(CTPV).Methods From January 1,2015 to December 31,2018,the clinical data of liver cirrhosis patients with EGVB and complicated with(CTPV group)or without(non-CTPV group)CTPV receiving TIPS at Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School were retrospectively analyzed.展开更多
In vitro morphogenesis of inflorescences from the cultured corn seedling shoot tips was obtained on modified Murashige and Skoog (MS) medium in complete darkness. Some shoot tip meristems excised from seedlings of inb...In vitro morphogenesis of inflorescences from the cultured corn seedling shoot tips was obtained on modified Murashige and Skoog (MS) medium in complete darkness. Some shoot tip meristems excised from seedlings of inbred line 515, inbred line 8112 and their filial generations would directly give rise to florets on modified MS medium supplemented with 2.0 mg/L N6-bezyladenine (6-BA) in five or six weeks. On the medium with 1.0 mg/L 6-BA and 0. 2 mg/L 2, 4-dichlorophenoxy acetic acid (2, 4-D), the explants swelled first, and produced multiple shoot clumps, then the culture of the shoot tips from all of the six inbred lines in experiment would ultimately initiate to develop ears and tassels accompanied by multiple shoot clumps developing on the medium with 1.0 mg/L 6-BA and 0. 2 mg/Lin-dole-3-butyric acid (IBA). The developmental patterns of the corn inflorescences were similar to the controls of normal plants in the field, but the number of the ears was much more than that of the tassels in vitro. It seemed that proper kinds and concentrations of exogenous hormones were necessary for the initiation and development of the inflorescences. The genotype of explants was responsible for the response to culture conditions. It could be inferred that there were different control mechanisms existing in the vegetative and reproductive developmental processes of maize, because the cultured shoot tips could directly produce the reproductive organs.展开更多
文摘Objective:To evaluate the effect and efficiency of ear tip bloodletting combined with Xianfang Huoming Yin(XFH)in the treatment of early-stage wheals.Methods:70 patients with early-stage wheals admitted from September 2020 to September 2022 were divided into two groups by randomized numerical table method,with 35 cases/group.Both groups received conventional treatment,the control group combined with XFH,and the observation group combined with ear tip bloodletting therapy and XFH.Conscious symptom scores,ocular indexes,therapeutic effects,and sleep quality between the two groups were compared.Results:After the treatment,the patients in the observation group had lower self-awareness symptom scores and sleep quality scores as compared to those in the control group;the diameter of the mass in the observation group was smaller than that of the control group after treatment;the average tear film rupture time and the time taken for the first non-contact tear film to rupture were longer in the observation group than those in the control group;the total effective rate of the treatment in the observation group was higher than that of the control group(P<0.05).Conclusion:Ear tip bloodletting combined with XFH was ideal for the treatment of early-stage wheals and has a high effective rate.
基金fnancially supported by the National Key Research and Development Program of China(2018YFD0300704)the Special Funds for Public Welfare Industry(Agriculture)Research,China(201203029)+1 种基金the Open Foundation of State Key Laboratory of Crop Biology in China(2019KF03)the Open Foundation of Chinese Academy of Agricultural Sciences,China/Key Laboratory of Crop Water Use and Regulation,Ministry of Agriculture and Rural Affairs,China(FIRI2019-02-0103)。
文摘Compared to other crops,maize production demands relatively high temperatures.However,temperatures exceeding 35℃lead to adverse effects on maize yield.High temperatures(≥35℃)are consistently experienced by summer maize during its reproductive growth stage in the North China Plain,which is likely to cause irreversible crop damage.This study investigated the effects of elevating temperature(ET)treatment on the yield component of summer maize,beginning at the 9th unfolding leaf stage and ending at the tasseling stage.Results demonstrated that continuous ET led to a decrease in the elongation rate and activity of silks and an elongated interval between anthesis and silking stages,and eventually decreased grain number at ear tip and reduced yield.Although continuous ET before tasseling damaged the anther structure,reduced pollen activity,delayed the start of the pollen shedding stage,and shortened the pollen shedding time,it was inferred,based on phenotypical and physiological traits,that continuous ET after the 9th unfolding leaf stage influenced ears and therefore may have more significant impacts.Overall,when maize plants were exposed to ET treatment in the ear reproductive development stage,the growth of ears and tassels was blocked,which increased the occurrence of barren ear tips and led to large yield losses.
文摘The aim of this paper is to study the inheritance pattern of ear tip-barrenness trait in maize (Zea mays L.). Ear tipbarrenness trait in maize can be classified into two types, tip-barren and tip-barrenless. Two inbred lines, lx01-3 (tipbarrenless type), wx04-1 (tip-barren type), and their F1, F2, BC1, BC2 generations were analyzed on their ear tip-barrenness types. Results showed that F1 was tip-barren type; the ratio of tip-barren type versus tip-barrenless type followed a 12.78: 1 ratio in F2 segregation population and a 2.75:1 ratio in BC1. Z2 test indicated that the trait of ear tip-barrenness type followed an inheritance pattern of 2 duplicate dominant genes. SPSS analysis indicated that the trait of ear tip-barrenness length is of abnormal distribution. Above results mean that: (1) The trait of maize ear tip-barrenness type is controlled by 2 duplicate dominant genes; tip-barren type is dominant over tip-barrenless type; (2) the trait of tip-barrenness length is a quantitative character controlled by polygene with major genes expected.
文摘目的 探讨经皮门静脉穿刺改良经颈内静脉肝内门体分流术(TIPS)较常规TIPS方法的优越性及临床疗效.方法 回顾性分析空军总医院2009年3月~2011年9月采用TIPS技术治疗门脉高压急性上消化道出血患者36例,其中15例采用常规TIPS技术,21例采用经皮肝穿刺门静脉造影改良TIPS技术.结果 改良TIPS组与常规TIPS组相比,手术时间显著缩短(183.69±56.77 vs 140.32±43.56)、手术开始至胃冠状静脉封堵时间显著缩短(130.81±66.39 vs 12.53±13.18)、穿刺针数显著减少(7.57±3.14 vs 4.16±2.73)、改良TIPS组手术成功率100%,常规TIPS组手术成功率80%,两组治疗均可显著降低门静脉压力.结论 超声引导下经皮门静脉穿刺造影,可标识定位指导TIPS操作,并可在第一时间封堵胃冠状静脉出血,提高了TIPS穿刺的准确性和安全性,可行性优于常规TIPS操作方法.
文摘Background and Aim:Gastric varices are associated with high mortality.There have been conflicting reports on whether endoscopic treatment with cyanoacrylate or the placement of a transjugular intrahepatic portosystemic shunt(TIPS)is more effective in the treatment of gastric varices.We compared the outcomes of patients treated with cyanoacrylate glue or TIPS for the management of acute gastric variceal bleeding.Methods:The study was designed as a retrospective cohort analysis of patients undergoing either TIPS or endoscopic treatment with cyanoacrylate for acute gastric variceal bleeding at our institution from 2001 to 2011.Primary compared to studied between the two treatment modalities were the short-term treatment outcomes,including re-bleeding within 30 days,length of hospital stay and in-hospital mortality.Kaplan-Meier survival analysis was performed to assess factors associated with in-hospital mortality.Results:A total of 169 patients were included in the analysis.The TIPS arm contained 140 patients and the cyanoacrylate arm contained 29 patients.There was no evidence to suggest any significant differences in demographics or disease severity.There were no differences between the TIPS arm and the cyanoacrylate armtwo groups in treatment outcomes including re-bleeding within 30 days(17.4%vs.17.2%;P=0.98),median length of stay in the hospital(4.5 days vs.6.0 days;P紏0.35)or in-hospital mortality(9.0%vs.11.1%;P=0.74).In-hospital mortality was evaluated for 149 patients and lower albumin(P=0.015),higher MELD score(P<0.001),higher CTP score(P=0.005)and bleeding(P=0.008)were all significantly associated with in-hospital death.Conclusion:These findings suggest that both treatments are equally effective.Cyanoacrylate offers a safe,effective alternative to TIPS for gastric varices,and physician may choose the best therapy for each patient,factoring in the availability of TIPS or cyanoacrylate,the individual patient’s presentation,and cost.
文摘AIM: To identify all cases of bacteremia and suspected endotipsitis after Transjugular intrahepatic portosystemic shunting (TIPS) at our institution and to determine risk factors for their occurrence. METHODS: We retrospectively reviewed records of all patients who underwent TIPS in our institution between 1996 and 2009. Data included: indications for TIPS, underlying liver disease, demographics, positive blood cultures after TIPS, microbiological characteristics, treat- ment and outcome. RESULTS: 49 men and 47 women were included with a mean age of 55.8 years (range 15-84). Indications for TIPS included variceal bleeding, refractory ascites,hydrothorax and hepatorenal syndrome. Positive blood cultures after TIPS were found in 39/96 (40%) patients at various time intervals following the procedure. Seven patients had persistent bacteremia fitting the definition of endotipsitis. Staphylococcus species grew in 66% of the positive cultures, Candida and enterococci species in 15% each of the isolates, and 3% cultures grew other species. Multi-variate regression analysis identified 4 variables: hypothyroidism, HCV, prophylactic use of an- tibiotics and the procedure duration as independent risk factors for positive blood cultures following TIPS (P < 0.0006, 0.005, 0.001, 0.0003, respectively). Prophylactic use of antibiotics before the procedure was associated with a decreased risk for bacteremia, preventing mainly early infections, occurring within 120 d of the procedure. CONCLUSION: Bacteremia is common following TIPS. Risk factors associated with bacteremia include failure to use prophylactic antibiotics, hypothyroidism, HCV and a long procedure. Our results strongly support the use of prophylaxis as a means to decrease early post TIPS infections.
文摘Objective To explore the safety and efficacy of transjugular intrahepatic portosystemic shunt(TIPS)in the treatment of esophago-gastric variceal bleeding(EGVB)complicated with cavernous transformation of portal vein(CTPV).Methods From January 1,2015 to December 31,2018,the clinical data of liver cirrhosis patients with EGVB and complicated with(CTPV group)or without(non-CTPV group)CTPV receiving TIPS at Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School were retrospectively analyzed.
文摘In vitro morphogenesis of inflorescences from the cultured corn seedling shoot tips was obtained on modified Murashige and Skoog (MS) medium in complete darkness. Some shoot tip meristems excised from seedlings of inbred line 515, inbred line 8112 and their filial generations would directly give rise to florets on modified MS medium supplemented with 2.0 mg/L N6-bezyladenine (6-BA) in five or six weeks. On the medium with 1.0 mg/L 6-BA and 0. 2 mg/L 2, 4-dichlorophenoxy acetic acid (2, 4-D), the explants swelled first, and produced multiple shoot clumps, then the culture of the shoot tips from all of the six inbred lines in experiment would ultimately initiate to develop ears and tassels accompanied by multiple shoot clumps developing on the medium with 1.0 mg/L 6-BA and 0. 2 mg/Lin-dole-3-butyric acid (IBA). The developmental patterns of the corn inflorescences were similar to the controls of normal plants in the field, but the number of the ears was much more than that of the tassels in vitro. It seemed that proper kinds and concentrations of exogenous hormones were necessary for the initiation and development of the inflorescences. The genotype of explants was responsible for the response to culture conditions. It could be inferred that there were different control mechanisms existing in the vegetative and reproductive developmental processes of maize, because the cultured shoot tips could directly produce the reproductive organs.