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The blocking effect of the sand fences quantified using wind tunnel simulations 被引量:3
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作者 YU Yan-ping ZHANG Ke-cun +2 位作者 AN Zhi-shan WANG Tao HU Fei 《Journal of Mountain Science》 SCIE CSCD 2020年第10期2485-2496,共12页
Fences are one of the most effective measures to prevent and control wind-blown sand disasters,and the blocking effect of fences is largely determined by their porosity and height(H).This study employed wind tunnel ex... Fences are one of the most effective measures to prevent and control wind-blown sand disasters,and the blocking effect of fences is largely determined by their porosity and height(H).This study employed wind tunnel experiments to measure wind velocities on both sides of wire mesh sand fences with porosities of 75%,63%,56%,36%and heights of 10,5 and 2 cm.The effects of porosity and height on the blocking effect of the fences were evaluated on the basis of velocity variability,flow field,and the wind velocity reduction coefficient.Results show that the smaller the porosity,the stronger the blocking effect.The fence with a porosity of 36%had the strongest windproof efficiency of 0.70 and longest protection range of 9 H,and thus showed the best applicability in preventing and controlling wind-blown sand disasters.The fence with a porosity of 56%showed a windproof efficiency of 0.31 and a protection range of 7 H,which could be considered for adoption.However,fences with porosities of 75%and 63%were not recommended to be adopted,because their windproof efficiency and protection range were very small.Overall,the higher the fence,the stronger the blocking effect.The highest fence(10 cm)had the longest protection range of 90 cm,which was the best in application.Nevertheless,the 5 and 2 cm fences were almost consistent with 10 cm fence in windproof efficiency,which was still suitable for wind and sand fixation. 展开更多
关键词 Porous fence Fence height Windproof efficiency Protection range blocking effect
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Water blocking effect caused by the use of hydraulic methods for permeability enhancement in coal seams and methods for its removal 被引量:9
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作者 Liu Qian Guo Yusen +2 位作者 An Fenghua Lin Luyao Lai Yongming 《International Journal of Mining Science and Technology》 SCIE EI CSCD 2016年第4期615-621,共7页
To research techniques for removing the water blocking effect caused by hydraulic applications in coal seams,the use of surfactants is proposed,based on the mechanics of the water blocking effect.Centrifugal experimen... To research techniques for removing the water blocking effect caused by hydraulic applications in coal seams,the use of surfactants is proposed,based on the mechanics of the water blocking effect.Centrifugal experiments were used to validate the effects of using surfactants;the results show that after dealing with vacuum saturation with water,the volume of micropores decreases,which results in a larger average pore size,and the volume of transitional pores,mesopores,macropores and total pores increases.Based on the distribution of pore size,the operation mode of ‘‘water infusion after gas extraction,then continuing gas extraction" is recommended to improve the volume of coal mine gas drainage.When the reflectance of vitrinite in coal samples is less than 1,using the surfactants Fast T,1631,APG,BS can mitigate the damage caused by the water blocking effect.But when the reflectance of vitrinite is larger than 1.4,the damage caused by the water blocking effect can be increased.When the surfactant CMC is used in hydraulic applications,the capillary forces of coal samples are almost negative,which means the capillary force is in the same direction as the gas extraction.The direction of capillary forces benefits the gas flow.So,using CMC can play an active role in removing the water blocking effect.Centrifugal experiments confirm that using CMC can effectively remove the water blocking effect,which has a beneficial effect on improving the gas drainage volume. 展开更多
关键词 煤层透气性 堵水效果 水力 表面活性剂 镜质体反射率 羧甲基纤维素钠 毛细管力 矿井瓦斯
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Blocking Effects of Spleen Vaccine on Vertical Transmission of Classical Swine Fever Virus in Sows 被引量:1
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作者 LIU Xin-ping GAO Lin +3 位作者 XU Jun-jie FENG Xuan-biao HUANG Jian-hua YANG Feng-mei 《Animal Husbandry and Feed Science》 CAS 2010年第5期24-25,28,共3页
[ Objective] To investigate the blocking effects of spleen vaccine on vertical transmission of classical swine fever virus (CSFV) in sows. [ Method] Sows infected by CSFV were selected from three large-scale pig far... [ Objective] To investigate the blocking effects of spleen vaccine on vertical transmission of classical swine fever virus (CSFV) in sows. [ Method] Sows infected by CSFV were selected from three large-scale pig farms and they were randomly divided into group Ⅰ, group Ⅱ and control group. The sows in the group Ⅰ were vaccinated with CSF spleen vaccine at a 1.5 times normal dose per pig; those in the group Ⅱ were vaccinated with CSF spleen vaccine at a 2.0 times normal dose per pig; and those in the control group were vaccinated with cell vaccine at a 4.0 times normal- dose per pig. The CSF antigens of piglets were detected by enzyme-linked immunosorbent assay (ELISA). [ Result] The antigen positive rate of piglets in the experimental group (18.5%) was significantly lower than that in the control group (48.1% ). No significant difference was found be- tween the group Ⅰ and the group Ⅱ. [ Condmion] CSF spleen vaccine has good blocking effects on vertical transmission of CSFV in sows. 展开更多
关键词 Classical swine fever spleen vaccine SOWS Vertical transmission blocking effects
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The Blocking Effect of Phenolic Acid on N-Nitrosomorpholine Formation in vitro 被引量:2
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作者 LI PlNG WANG HUAI-ZHOU WANG XU-QING AND WU YONG-NING(Institute of Nutrition and Food Hygiene, Chinese Academy of PreventiveMedicine, 29 Nanwei Road, Beijing 100050, China)( Present address: Institute of Environmental Health and Engineering, Chinese Acad 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 1994年第1期68-78,共11页
Phenolic acids (PAs) are widely found in many daily consumed vegetables and fruits.The inhibitory effects of PAs on Nnitrosomorpholine (NMOR) formation in vitro undersimulated gastric juice condition were studied. The... Phenolic acids (PAs) are widely found in many daily consumed vegetables and fruits.The inhibitory effects of PAs on Nnitrosomorpholine (NMOR) formation in vitro undersimulated gastric juice condition were studied. The results showed that the inhibjtoryIX)tency of thirteen varieties of PAs differed greatly, which may be related to theirchemical structures; the blocking rate (BR) of different killds of PAs were as follows:caf feic acid, 92.5%; tannic acid, 90.0%; gallic acid, 86.8%; sinaPinic acid, 86.2%; ferulicacid, 8l.l%; chlorogenic acid, 69.4%; gentisic acid, 69.2%; syringic acid, 62.1%; protocatechuic acid, 56.0%; p-coumaric acid, 52.5%; vannilic acid, 35.4%; moreover,p-hydroxybenzoic acid and m-coumaric acid had the least blocking effect or even slightcatalyzing effect. The results also demonstrated that amounts of NMOR formed werenegatively correlated with molar ratio of PAs to nitrite and that the optimum pH forinhibition was between 2 and 3. 展开更多
关键词 The blocking effect of Phenolic Acid on N-Nitrosomorpholine Formation in vitro
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Effect of cerebral lymphatic block on cerebral morphology and cortical evoked potential in rats
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作者 Zuoli Xia1, Baoliang Sun2, Mingfeng Yang1, Dongmei Hu2, Tong Zhao2, Jingzhong Niu2 1Institute of Brain Microcirculation, Taishan Medical College, Taian 271000, Shandong Province, China 2Department of Neurology, Affiliated Hospital of Taishan Medical College, Taian 271000, Shandong Province, China 《Neural Regeneration Research》 SCIE CAS CSCD 2006年第7期657-660,共4页
BACKGROUND: It has been shown that although brain does not contain lining endothelial lymphatic vessel, it has lymphatic drain. Anterior lymphatic system of lymphatic vessel in brain tissue plays a key role in introdu... BACKGROUND: It has been shown that although brain does not contain lining endothelial lymphatic vessel, it has lymphatic drain. Anterior lymphatic system of lymphatic vessel in brain tissue plays a key role in introducing brain interstitial fluid to lymphatic system; however, the significance of lymphatic drain and the effect on cerebral edema remains unclear. OBJECTIVE: To investigate the effect of cerebral lymphatic block on cerebral morphology and cortical evoked potential in rats. DESIGN: Randomized controlled animal study. SETTING: Institute of Cerebral Microcirculation of Taishan Medical College and Department of Neurology of Affiliated Hospital. MATERIALS: A total of 63 healthy adult male Wistar rats weighing 300-350 g were selected in this study. Forty-seven rats were used for the morphological observation induced by lymphatic drain and randomly divided into three groups: general observation group (n =12), light microscopic observation group (n =21) and electronic microscopic observation group (n =14). The rats in each group were divided into cerebral lymphatic block subgroup and sham-operation control subgroup. Sixteen rats were used for observing the effect of cerebral lymphatic block on cortical evoked potential, in which the animals were randomly divided into sham-operation group (n =6) and cerebral lymphatic block group (n =10). METHODS: The experiment was carried out in the Institute of Cerebral Microcirculation of Taishan Medical College from January to August 2003. Rats in cerebral lymphatic block group were anesthetized and separated bilateral superficial and deep cervical lymph nodes under sterile condition. Superior and inferior boarders of lymph nodes were ligated the inputting and outputting channels, respectively, and then lymph node was removed so as to establish cerebral lymphatic drain disorder models. Rats in sham-operation control group were not ligated the lymphatic vessel and removed lymph nodes, and other operations were as the same as those in cerebral lymphatic block group. Morphological changes of the brain and alterations of latency of cortical evoked potential were detected on the 1st, 2nd, 3rd, 5th, 7th, 10th and 15th days after operation under general, light microscope and electronic microscope observations. MAIN OUTCOME MEASURES: ① Cerebral morphological changes; ② latent changes of cortical evoked potential. RESULTS: A total of 63 rats were involved in the final analysis. ① Cerebral morphological changes: General observation showed that, for cerebral lymphatic block rats, the surface of brain was pale and full, and cerebral gyrus was wide and flattened sulci after cerebral lymphatic block; and cerebral tissue space prolongation, increased interstitial fluid, neuronal degeneration and necrosis, diffused phagocytes and satellitosis were observed under light microscope. Neuronal swell and necrosis, glial cell swell, apparent subcellular changes such as mitochondron were observed under electronic microscope. ② Latent changes of cortical evoked potential: As compared with sham-operation control group, latency of cortical evoked potential in cerebral lymphatic blockage group prolonged on the 5th day and 7th day after cerebral lymphatic block [(6.28±0.23), (6.97±0.35) ms; (6.23±0.22), (7.12±0.20) ms; P < 0.01]. CONCLUSION: ① Cerebral lymphatic block plays an important role in cerebral morphology, and may result in abnormality of sensitive impulse conduction and prolong latency of cortical evoked potential. ② Examination of cortical evoked potential is easy and convenient, so it is regarded as a key index for lymphatic disturbed cerebral injury. 展开更多
关键词 effect of cerebral lymphatic block on cerebral morphology and cortical evoked potential in rats
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Blocking Response Surface Designs Incorporating Neigh-bour Effects
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作者 Eldho Varghese Seema Jaggi 《Open Journal of Statistics》 2011年第3期199-204,共6页
In this paper, blocking in response surface for fitting first order model incorporating neighbour effects has been investigated. The conditions for orthogonal estimation of the parameters of the model have been obtain... In this paper, blocking in response surface for fitting first order model incorporating neighbour effects has been investigated. The conditions for orthogonal estimation of the parameters of the model have been obtained. A method of constructing designs which ensures the constancy of variance of the parameter estimates of the model has also been given. 展开更多
关键词 RESPONSE SURFACE Model Neighbour effectS blockING in RESPONSE SURFACE Conditions for ORTHOGONAL Estimation
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Effect of Mg-Preflow for p-AlGaN Electron Blocking Layer on the Electroluminescence of Green LEDs with V-Shaped Pits
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作者 李爱星 莫春兰 +5 位作者 张建立 王小兰 吴小明 王光绪 刘军林 江风益 《Chinese Physics Letters》 SCIE CAS CSCD 2018年第2期88-92,共5页
In GaN-based green light-emitting diodes(LEDs) with and without Mg-preflow before the growth of p-Al GaN electron blocking layer(EBL) are investigated experimentally.A higher Mg doping concentration is achieved in... In GaN-based green light-emitting diodes(LEDs) with and without Mg-preflow before the growth of p-Al GaN electron blocking layer(EBL) are investigated experimentally.A higher Mg doping concentration is achieved in the EBL after Mg-preflow treatment,effectively alleviating the commonly observed efficiency collapse and electrons overflowing at cryogenic temperatures.However,unexpected decline in quantum efficiency is observed after Mg-preflow treatment at room temperature.Our conclusions are drawn such that the efficiency decline is probably the result of different emission positions.Higher Mg doping concentration in the EBL after Mg-preflow treatment will make it easier for a hole to be injected into multiple quantum wells with emission closer to pGaN side through the(8-plane rather than the V-shape pits,which is not favorable to luminous efficiency due to the preferred occurrence of accumulated strain relaxation and structural defects in upper QWs closer to p-GaN.Within this framework,apparently disparate experimental observations regarding electroluminescence properties,in this work,are well reconciled. 展开更多
关键词 GaN EBL effect of Mg-Preflow for p-AlGaN Electron blocking Layer on the Electroluminescence of Green LEDs with V-Shaped Pits
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Left- and Right-Handers May Unintentionally Apply Different Cognitive Strategies in Response to Situational Demands: Study Using the Block-Wise Proportion Congruency Effect
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作者 Kazuhito Yoshizaki Yurina Watanabe 《Journal of Behavioral and Brain Science》 2022年第1期10-21,共12页
We investigated the effects of handedness on developing latent cognitive response strategies according to situation variables. We used the findings of the block-wise Proportion Congruency (PC) effect in which the prop... We investigated the effects of handedness on developing latent cognitive response strategies according to situation variables. We used the findings of the block-wise Proportion Congruency (PC) effect in which the proportion of congruent trials in a given block modulates the compatibility effect in its block. The block-wise PC effect cannot be intentionally controlled. A Simon task with three different types of Proportion Congruency (PC) in a given block was used to measure the block-wise PC effects. This task was administered to 24 left-handed and 24 right-handed participants. The reaction time and error rates, consistent with previous studies, demonstrated that the block-wise PC effect was observed in left- and right-handers. Crucially, the block-wise PC effect was more pronounced in left- than right-handers, suggesting that left- and right-handers unintentionally apply different cognitive strategies in response to conflict resolution experiences. 展开更多
关键词 Cognitive Control Handedness block-Wise Proportion Congruency (PC) effect
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槽式太阳能阵列挡风增速效果数值模拟
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作者 张立栋 李佩 +4 位作者 姜铁骝 李钦伟 张磊 徐峰 孟欣 《综合智慧能源》 CAS 2024年第6期1-7,共7页
采用开源计算流体力学软件OpenFOAM中的Simple求解器对流场进行数值模拟,研究5.00 m/s风速下槽式太阳能阵列挡风墙挡风效果。对由槽式太阳能阵列组成的6个不同高度的挡风墙对整体流场速度的影响以及不同高度挡风墙背风侧30,60,90 m处的... 采用开源计算流体力学软件OpenFOAM中的Simple求解器对流场进行数值模拟,研究5.00 m/s风速下槽式太阳能阵列挡风墙挡风效果。对由槽式太阳能阵列组成的6个不同高度的挡风墙对整体流场速度的影响以及不同高度挡风墙背风侧30,60,90 m处的速度进行了分析。研究发现,当气流通过挡风墙时,低于墙高的位置速度大幅衰减,而高于墙高的位置开始加速,存在明显的分区作用。当气流流过挡风墙后,会在其后形成明显的速度衰减区,其面积和延伸与挡风墙的高度正相关。在挡风墙背风侧较远处,高于墙高的气流开始减速,低于墙高的气流开始加速,并随着距离的增加风速逐渐趋于平稳。 展开更多
关键词 槽式太阳能 挡风墙 挡风效果 速度衰减区 OPENFOAM 数值模拟
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0.25%罗哌卡因用于超声引导颈中间丛阻滞的有效容量探讨
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作者 陈晓影 蒋俊丹 +1 位作者 龚灿生 郑晓春 《中国现代药物应用》 2024年第8期111-114,共4页
目的探索0.25%罗哌卡因用于超声引导颈中间丛阻滞的半数有效容量和95%有效容量。方法选择29例行择期颈部手术的患者,均在超声引导下进行0.25%罗哌卡因颈中间丛阻滞,若颈丛分支所属皮区痛觉均消失,则视为完全阻滞(完全阻滞组,14例),否则... 目的探索0.25%罗哌卡因用于超声引导颈中间丛阻滞的半数有效容量和95%有效容量。方法选择29例行择期颈部手术的患者,均在超声引导下进行0.25%罗哌卡因颈中间丛阻滞,若颈丛分支所属皮区痛觉均消失,则视为完全阻滞(完全阻滞组,14例),否则视为不完全阻滞(不完全阻滞组,15例)。记录阻滞效果,分析0.25%罗哌卡因用于超声引导颈中间丛阻滞的有效容量;比较完全阻滞组和不完全阻滞组患者的一般特征、罗哌卡因阻滞容量、并发症发生情况及阻滞前后深吸气膈肌移动度。结果0.25%罗哌卡因用于超声引导颈中间丛阻滞的半数有效容量为10.3 ml[95%可信区间(CI)=(7.7,13.5)ml],95%有效容量为15.6 ml[95%CI=(12.8,44.0)ml]。完全阻滞组和不完全阻滞组年龄、性别、美国麻醉医师协会(ASA)分级、身高、体重及体质量指数(BMI)比较差异无统计学意义(P>0.05)。完全阻滞组用罗哌卡因容量(11.1±2.0)ml显著高于不完全阻滞组的(9.2±2.0)ml,差异有统计学意义(P<0.05)。不完全阻滞组与完全阻滞组阻滞前深吸气膈肌移动度分别为(4.17±0.87)、(4.09±0.85)cm,比较差异无统计学意义(P>0.05);不完全阻滞组与完全阻滞组阻滞后深吸气膈肌移动度分别为(4.09±0.85)、(3.99±0.70)cm,比较差异无统计学意义(P>0.05)。完全阻滞组1例患者发生声音嘶哑,其给药容量为14 ml;其余所有患者均未发生膈神经阻滞、迷走神经阻滞、局部麻醉药物中毒、Horner征或低氧血症等情况。结论0.25%罗哌卡因用于超声引导颈中间丛阻滞的半数有效容量为10.3 ml[95%CI=(7.7,13.5)ml],95%有效容量为15.6 ml[95%CI=(12.8,44.0)ml]。 展开更多
关键词 颈中间丛阻滞 罗哌卡因 有效容量 Dixon序贯法
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青藏高原1990年以来的M_W≥6.5强震事件及活动构造体系控震效应 被引量:3
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作者 吴中海 《地震科学进展》 2024年第1期10-24,共15页
深入认识青藏高原陆陆碰撞-挤出构造体系作用下的强震活动特点及未来强震活动趋势,对于区域防震减灾具有重要科学意义。统计分析青藏高原及邻区1900年以来的M≥6.0强震活动发现,青藏高原自1950年西藏墨脱—察隅8.6级大地震以来正处于新... 深入认识青藏高原陆陆碰撞-挤出构造体系作用下的强震活动特点及未来强震活动趋势,对于区域防震减灾具有重要科学意义。统计分析青藏高原及邻区1900年以来的M≥6.0强震活动发现,青藏高原自1950年西藏墨脱—察隅8.6级大地震以来正处于新一轮相对缓慢的地震能释放期,但1990年以来的强震发生率和地震释放能显示出逐步增高趋势,并可能预示下一轮地震能快速释放期的临近。活动构造体系控震分析表明,青藏高原陆陆碰撞-挤出构造体系中的“多层次挤出-旋转活动构造体系”构成了1990年以来新一轮M_W≥6.5强震活动的主要控震构造,尤其是其中的巴颜喀拉挤出构造单元的强震活动最为显著,指示其目前正处于构造活跃状态,而且这一状态可能仍将持续。综合研究认为,在区域强震活动趋势分析中,充分认识活动构造体系控震效应,将有助于更好地分析判断区域未来强震时空迁移过程及最可能出现的构造部位。考虑到当前强震活动过程中,青藏高原“多层次挤出-旋转活动构造体系”的未来强震活动趋势仍会持续,需要重点关注挤出块体边界上3条大型左旋走滑断裂带,阿尔金—祁连—海原断裂系、东昆仑断裂带和鲜水河—小江断裂带的未来强震危险性,其次是断块内部断裂。 展开更多
关键词 青藏高原 陆陆碰撞-挤出构造体系 强震事件 巴颜喀拉断块 构造体系控震效应
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竖脊肌平面阻滞在老年胸腔镜肺叶切除术患者中的应用效果
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作者 刘克 王宁 +3 位作者 陈丹 闫炳文 赵培娟 张婷婷 《中国现代医学杂志》 CAS 2024年第12期68-72,共5页
目的分析竖脊肌平面阻滞在老年胸腔镜肺叶切除术中的应用效果。方法选取2021年2月—2023年3月胜利油田中心医院行胸腔镜肺叶切除术的98例患者,采用随机数字表法分为对照组和研究组,每组49例。研究组给予竖脊肌平面阻滞联合无阿片类药物... 目的分析竖脊肌平面阻滞在老年胸腔镜肺叶切除术中的应用效果。方法选取2021年2月—2023年3月胜利油田中心医院行胸腔镜肺叶切除术的98例患者,采用随机数字表法分为对照组和研究组,每组49例。研究组给予竖脊肌平面阻滞联合无阿片类药物全身麻醉,对照组给予阿片类全身麻醉。比较两组T_(0)(麻醉诱导前)、T_(1)(气管插管时)、T_(2)(切皮时)、T_(3)(手术结束)的平均动脉压、心率,对比两组手术情况、术后疼痛、苏醒期间躁动情况及药物不良反应情况。结果两组T_(0)、T_(1)、T_(2)、T_(3)的平均动脉压比较,结果:(1)不同时间点的平均动脉压比较,差异有统计学意义(P<0.05);(2)两组平均动脉压比较,差异无统计学意义(P>0.05);(3)两组平均动脉压的变化趋势比较,差异无统计学意义(P>0.05)。两组T_(0)、T_(1)、T_(2)、T_(3)时刻心率比较,结果:(1)不同时间点的心率比较,差异有统计学意义(P<0.05);(2)两组心率比较,差异无统计学意义(P>0.05);(3)两组心率的变化趋势比较,差异无统计学意义(P>0.05)。两组手术时间比较,差异无统计学意义(P>0.05)。研究组术后苏醒时间、拔管时间短于对照组(P<0.05)。两组术后4、12、24和48 h的疼痛视觉模拟评分(VAS)比较,结果:(1)不同时间点的VAS评分比较,差异有统计学意义(P<0.05);(2)两组VAS评分比较,差异有统计学意义(P<0.05),研究组低于对照组,相对镇痛效果较好;(3)两组VAS评分的变化趋势比较,差异有统计学意义(P<0.05)。研究组苏醒期躁动发生率低于对照组(P<0.05)。研究组不良反应总发生率低于对照组(P<0.05)。结论竖脊肌平面阻滞用于老年胸腔镜肺叶切除术安全可行,可避免使用阿片类药物,并可减轻术后疼痛,降低苏醒期躁动发生风险,减少围手术期不良反应,有利于患者快速康复。 展开更多
关键词 竖脊肌平面阻滞 胸腔镜肺叶切除术 全身麻醉 效果
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开腹子宫切除术中QLB-LSAL与双侧TAPB阻滞麻醉镇痛效果比较
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作者 聂亮 胡芸 +1 位作者 伍伦权 张雪峰 《中国计划生育学杂志》 2024年第2期317-321,共5页
目的:分析超声引导下外侧弓状韧带上腰方肌前路阻滞(QLB-LSAL)与双侧腹横肌平面阻滞(TAPB)在开腹子宫切除术(TAH)中的麻醉效果。方法:选取2022年1月-2023年1月本院择期行TAH患者95例,根据入院顺序按单双号分为48例QLB-LSAL组(超声引导... 目的:分析超声引导下外侧弓状韧带上腰方肌前路阻滞(QLB-LSAL)与双侧腹横肌平面阻滞(TAPB)在开腹子宫切除术(TAH)中的麻醉效果。方法:选取2022年1月-2023年1月本院择期行TAH患者95例,根据入院顺序按单双号分为48例QLB-LSAL组(超声引导下行双侧QLB-LSAL)和47例TAPB组(超声引导下行双侧TAPB),比较两组入室(T0)、切皮时(T1)、手术结束时(T2)、拔管时(T3)及离开麻醉恢复室时(T4)的心率(HR)及平均动脉压(MAP),比较术后48h舒芬太尼消耗量、补救镇痛例数及术后48h内镇痛泵按压次数,比较术后4h、8h、12h、24h静息及咳嗽时视觉疼痛模拟评分(VAS),统计两组术后不良反应和神经阻滞并发症发生情况。结果:两组MAP及HR均呈先上升后降低趋势,且QLB-LSAL组在T1和T2时低于TAPB组(P<0.05);QLB-LSAL组术后48h舒芬太尼消耗量(69.45±4.20μg)、补救镇痛(6.3%)及术后48h内镇痛泵按压(10.5±2.3次)均低于TAPB组(73.15±4.35μg、21.3%、12.2±4.4次)(均P<0.05);两组术后静息及咳嗽时VAS评分均呈降低趋势(P<0.05),两组术后4h、8h评分无差异(P>0.05),术后12h、24h静息及咳嗽时评分QLB-LSAL组低于TAPB组(均P<0.05);两组不良反应(6.3%、4.3%)无差异(P>0.05),两组均无神经阻滞情况发生。结论:相比于双侧TAPB阻滞,超声引导下QLB-LSAL阻滞在TAH中镇痛效果更佳,能有效降低镇痛药物使用剂量,减轻受术患者的疼痛应激反应。 展开更多
关键词 开腹子宫切除术 腰方肌前路阻滞 腹横肌平面阻滞 镇痛效果
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不同粗糙度煤岩界面超低摩擦效应与声发射特征试验研究
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作者 李利萍 胡学锦 +1 位作者 潘一山 孙媛涛 《力学学报》 EI CAS CSCD 北大核心 2024年第4期1047-1056,共10页
为了揭示动载扰动作用下煤岩界面粗糙度对超低摩擦型冲击地压影响机制,采用自行研制的煤岩界面超低摩擦试验装置,以沈阳红阳三矿1082 m采深煤岩体为研究对象,通过改变煤块与砂岩块体表面粗糙度来模拟煤岩界面不同粗糙特性,以粗糙度系数... 为了揭示动载扰动作用下煤岩界面粗糙度对超低摩擦型冲击地压影响机制,采用自行研制的煤岩界面超低摩擦试验装置,以沈阳红阳三矿1082 m采深煤岩体为研究对象,通过改变煤块与砂岩块体表面粗糙度来模拟煤岩界面不同粗糙特性,以粗糙度系数表征煤岩界面粗糙程度,工作块体水平位移表征冲击过程中超低摩擦效应强度,声发射能量为工作块体摩擦滑动过程中的信号参数,进行应力波扰动下不同粗糙度煤岩界面超低摩擦试验.研究结果表明:(1)超低摩擦滑动过程中,工作块体水平位移、声发射能量计数以及累计能量曲线呈现出孕育阶段、激发阶段、稳定阶段变化特征;(2)煤岩界面粗糙度越小,工作块体水平位移和声发射能量峰值越大,煤岩界面越易发生超低摩擦效应;(3)不同煤岩界面粗糙度下,相比于其他扰动频率, 2 Hz时更易发生超低摩擦效应;(4)给出了声发射能量峰值与煤岩界面粗糙度系数对应关系.声发射能量峰值可以有效表征超低摩擦效应强度,可以用声发射能量峰值预测超低摩擦效应强度. 展开更多
关键词 煤岩界面 粗糙度 煤岩块体 超低摩擦效应 声发射信号
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星状神经节阻滞用于慢性主观性耳鸣困扰的辅助干预效果及预测指标初析
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作者 黎志成 程楠 +5 位作者 邢纪斌 田家旺 赵鉴祺 田华静 林嘉怡 曾祥丽 《中山大学学报(医学科学版)》 CAS CSCD 北大核心 2024年第2期276-282,共7页
【目的】探讨星状神经节阻滞(SGB)用于慢性主观性耳鸣困扰的辅助干预效果,及相应的预测指标,为SGB应用于耳鸣的临床干预累积经验。【方法】回顾因其他干预方案效果不理想而在中山大学附属第三医院耳鼻咽喉-头颈外科接受SGB干预的慢性主... 【目的】探讨星状神经节阻滞(SGB)用于慢性主观性耳鸣困扰的辅助干预效果,及相应的预测指标,为SGB应用于耳鸣的临床干预累积经验。【方法】回顾因其他干预方案效果不理想而在中山大学附属第三医院耳鼻咽喉-头颈外科接受SGB干预的慢性主观性耳鸣患者资料。SGB干预前进行耳鸣残疾量表(THI)评估、纯音听阈测试、耳鸣响度评估,部分患者接受了睡眠质量(PSQI)评估。SGB干预后复测THI,以评价SGB的干预效果。随后,通过相关分析及线性回归方程探寻预测SGB干预效果的潜在指标。数据的统计分析采用SPSS 24.0进行,P<0.05表示存在统计学意义。【结果】至2023年04月,共有107名慢性主观性耳鸣患者接受了SGB干预,其中男性患者67名,女性患者40名,平均(45.32±11.40)周岁,耳鸣持续(20.32±24.64)月[16(12~20)]。有7名患者因个人原因中途退组,退组率6.54%,干预依从性良好。所有患者均未出现穿刺部位感染、血肿、神经损伤、局麻药中毒等不良反应,安全性良好。SGB干预后,有77名患者的THI得分下降至36分及以下,剩余的患者中有12名的THI得分下降幅度达到10分及以上,有效率为89%;配对样本t检验显示,SGB干预前后的THI得分有显著的统计学差异(t=15.575,P<0.001),干预效果良好。皮尔逊相关分析显示,干预前的THI得分和耳鸣主观响度与THI的改善水平呈显著的正相关关系(P<0.05);进一步的逐步线性回归分析发现,“干预前THI得分”具有显著的统计学意义(P<0.001),回归系数为0.308,预测了THI改善水平的17.4%。【结论】SGB干预慢性主观性耳鸣困扰的短期效果良好、安全性高,可用于常规干预方案不理想时(尤其是THI得分较高患者)的补充方案,但后续研究需要明确长期疗效及内在机制,为SGB应用于主观性耳鸣的干预奠定更为扎实的理论基础。 展开更多
关键词 慢性主观性耳鸣 星状神经节阻滞 耳鸣困扰 干预效果 预测指标
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超声引导下TAP阻滞对妇科腹腔镜手术患者麻醉效果及术后镇痛的影响
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作者 孟超 赵亚琴 《实用妇科内分泌电子杂志》 2024年第13期24-26,共3页
目的 探讨超声引导下TAP阻滞技术应用于妇科腹腔镜手术的麻醉效果及在术后镇痛方面的优势。方法 选取100例腹腔镜手术患者,根据随机数字表法将患者分为两组,每组50例。对照组应用常规静脉镇痛干预,试验组采用超声引导下TAP阻滞麻醉。比... 目的 探讨超声引导下TAP阻滞技术应用于妇科腹腔镜手术的麻醉效果及在术后镇痛方面的优势。方法 选取100例腹腔镜手术患者,根据随机数字表法将患者分为两组,每组50例。对照组应用常规静脉镇痛干预,试验组采用超声引导下TAP阻滞麻醉。比较两组患者心率、血压水平、手术麻醉效果、术后疼痛评分与镇痛状况。结果 试验组患者心率、血压水平、手术麻醉效果及术后疼痛评分与镇痛状况均明显优于对照组(P<0.05)。结论 超声引导下TAP阻滞可用于腹腔镜手术,对妇科疾病的手术治疗有着较为突出的麻醉作用,值得临床推广与应用。 展开更多
关键词 妇科腹腔镜手术 超声引导 TAP阻滞 麻醉效果 术后镇痛
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不同浓度罗哌卡因用于超声引导下TAP阻滞在妇科手术中的镇痛效果及安全性
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作者 邹蓉 杨程 +1 位作者 朱娟 张杰 《中国计划生育学杂志》 2024年第3期548-552,共5页
目的:探讨不同浓度罗哌卡因用于超声引导下腹横肌平面(TAP)阻滞在妇科手术中的临床效果。方法:将2021年4月-2023年4月于本院行全身麻醉下腹腔镜子宫全切术患者105例,依据双盲法分为3组,分别给予0.25%、0.30%、0.375%罗哌卡因。对比各组... 目的:探讨不同浓度罗哌卡因用于超声引导下腹横肌平面(TAP)阻滞在妇科手术中的临床效果。方法:将2021年4月-2023年4月于本院行全身麻醉下腹腔镜子宫全切术患者105例,依据双盲法分为3组,分别给予0.25%、0.30%、0.375%罗哌卡因。对比各组手术相关指标,不同时间点患者疼痛和舒适度评分变化,麻醉前后患者炎症因子水平,术后24h不良反应。结果:3组麻醉时间、术中出血量、手术时间均无差异(P>0.05);与术后1h对比,术后24h各组视觉模拟评分(VAS)均下降,Bruggrmann舒适度评分(BCS)均提升,但0.375%组VAS评分(1.56±0.51分)低于0.25%组(2.69±1.02分)、0.30%组(2.35±0.68分),BCS评分(3.24±0.54分)高于0.25%组(2.23±0.39分)、0.30%组(2.59±0.41分)(P<0.05);麻醉后各组C反应蛋白(CRP)、肿瘤坏死因子α(TNF-α)水平均提升,但0.375%组CRP(21.36±4.26 mg/L)、TNF-α(70.13±7.16 pg/ml)水平低于0.25%组(28.98±5.62 mg/L、96.54±8.97 pg/ml)、0.30%组(24.69±4.87 mg/L、84.33±7.62 pg/ml),不良反应发生率0.375%组(8.6%)低于0.25%组(40.0%)、0.30%组(31.4%)(均P<0.05)。结论:0.375%浓度罗哌卡因在超声引导下妇科TAP阻滞术中应用,改善患者疼痛效果显著,提升患者术后舒适度,有助于降低术后不良反应发生风险,提高用药安全性。 展开更多
关键词 妇科手术 超声引导 腹横肌平面阻滞术 罗哌卡因 不同浓度 麻醉效果 镇痛
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超声引导菱形肌-肋间肌阻滞和TPVB在电视胸腔镜手术术后早期疼痛控制中的应用比较
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作者 张莉莉 杨雅婷 贾倩倩 《临床和实验医学杂志》 2024年第8期894-896,F0003,共4页
目的 比较超声引导下菱形肌-肋间肌阻滞和胸椎旁神经阻滞(TPVB)对电视胸腔镜手术患者术后早期疼痛的控制效果。方法 前瞻性选取2022年1月至2023年7月秦皇岛市第一医院收治的120例行电视胸腔镜手术治疗的患者作为研究对象,按照信封法分... 目的 比较超声引导下菱形肌-肋间肌阻滞和胸椎旁神经阻滞(TPVB)对电视胸腔镜手术患者术后早期疼痛的控制效果。方法 前瞻性选取2022年1月至2023年7月秦皇岛市第一医院收治的120例行电视胸腔镜手术治疗的患者作为研究对象,按照信封法分为观察组(n=61)和对照组(n=59)。观察组采用静脉全身麻醉+超声引导菱形肌-肋间肌阻滞麻醉,对照组采用静脉全身麻醉+超声引导TPVB麻醉。比较两组患者手术指标、神经阻滞情况、视觉模拟评分法(VAS)评分、Ramsay镇静评分,统计两组患者并发症发生情况。结果 两组患者手术时间、术中出血量、引流时间、住院时间及首次进食时间比较,差异均无统计学意义(P>0.05)。两组注药时间、阻滞持续时间及补救镇痛次数比较,差异均无统计学意义(P>0.05);观察组超声定位时间、穿刺时间、操作总时间分别为(1.12±0.10)、(2.37±0.56)、(5.47±0.38)min,均短于对照组[(1.65±0.14)、(3.61±0.64)、(6.98±0.42) min],穿刺针深度为(4.43±0.52) mm,小于对照组[(5.37±0.58)mm],差异均有统计学意义(P<0.05)。两组患者术后6、12 h VAS评分、Ramsay镇静评分比较,差异均无统计学意义(P>0.05)。两组患者麻醉后恢复室(PACU)低氧血症发生率、气胸发生率、肺部感染发生率、肺不张发生率、恶心呕吐发生率及总并发症发生率比较,差异均无统计学意义(P>0.05)。结论 与TPVB比较,超声引导菱形肌-肋间肌阻滞应用于电视胸腔镜手术,患者术后恢复质量、镇痛效果及安全性相当,但超声引导菱形肌-肋间肌阻滞操作简单,操作时间更短。 展开更多
关键词 镇痛 全身麻醉 超声引导 菱形肌-肋间肌阻滞 胸椎旁神经阻滞 电视胸腔镜手术 镇痛效果
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右美托咪定复合地塞米松肋间神经阻滞用于老年肺癌患者胸腔镜根治术后镇痛的效果分析 被引量:3
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作者 李国威 马赛仙 +3 位作者 房朱红 司波 舒倩 闫智雯 《中国现代医学杂志》 CAS 2024年第2期38-44,共7页
目的 分析右美托咪定复合地塞米松肋间神经阻滞在老年肺癌患者胸腔镜根治术后镇痛中的效果。方法 选取2020年12月—2023年6月在无锡市第五人民医院行胸腔镜根治术的82例老年肺癌患者,采用随机数字表法分为对照组和研究组,每组41例。对... 目的 分析右美托咪定复合地塞米松肋间神经阻滞在老年肺癌患者胸腔镜根治术后镇痛中的效果。方法 选取2020年12月—2023年6月在无锡市第五人民医院行胸腔镜根治术的82例老年肺癌患者,采用随机数字表法分为对照组和研究组,每组41例。对照组术毕给予地塞米松复合罗哌卡因肋间神经阻滞,研究组术毕给予右美托咪定复合地塞米松、罗哌卡因肋间神经阻滞。比较两组肋间神经阻滞及术后静脉自控镇痛(PCIA)用药情况,对比两组围手术期疼痛、认知功能、应激反应、炎症反应及麻醉相关药物不良反应情况。结果 研究组肋间神经阻滞镇痛持续时间长于对照组,术后48 h舒芬太尼消耗总量少于对照组(P <0.05)。研究组与对照组术后4、12、24和48 h的视觉模拟评分(VAS)评分比较,结果:(1)不同时间点VAS评分比较,差异有统计学意义(F=9.156,P=0.000);(2)研究组与对照组VAS评分比较,差异有统计学意义(F=7.851,P=0.000);(3)两组VAS评分变化趋势比较,差异有统计学意义(F=7.061,P=0.000)。研究组与对照组术前及术后24和48 h的简易精神状态检查(MMSE)量表评分比较,结果:(1)不同时间点MMSE评分比较,差异无统计学意义(F=0.179,P=0.834);(2)研究组与对照组MMSE评分比较,差异无统计学意义(F=0.151,P=0.859);(3)两组MMSE评分变化趋势比较,差异无统计学意义(F=0.309,P=0.724)。研究组与对照组术前及术后24、48 h的肾上腺素(Adr)、皮质醇(Cor)比较,结果:(1)不同时间点Adr、Cor比较,差异均有统计学意义(F=7.967和8.043,均P=0.000);(2)研究组与对照组Adr、Cor比较,差异均有统计学意义(F=7.123和7.691,均P=0.000);(3)两组Adr、Cor变化趋势比较,差异均有统计学意义(F=8.003和7.961,均P=0.000)。研究组与对照组开始麻醉及术后24和48 h的肿瘤坏死因子α(TNF-α、)高迁移率族蛋白B1(HMGB1)比较,结果:(1)不同时间点TNF-α、HMGB1比较,差异均有统计学意义(F=8.236和8.417,均P=0.000);(2)研究组与对照组TNF-α、HMGB1比较,差异均有统计学意义(F=6.298和7.215,均P=0.000);(3)两组TNF-α、HMGB1变化趋势比较,差异均有统计学意义(F=7.035和7.152,均P=0.000)。两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论 右美托咪定复合地塞米松肋间神经阻滞用于老年肺癌患者胸腔镜根治术后镇痛可延长肋间神经阻滞时间,减少术后舒芬太尼消耗量,并可减轻术后疼痛、应激反应及炎症反应,且安全性良好。 展开更多
关键词 肺癌 胸腔镜根治术 右美托咪定 地塞米松 肋间神经阻滞 镇痛 效果
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Mechanisms of shale hydration and water block removal 被引量:3
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作者 ZENG Fanhui ZHANG Qiang +3 位作者 GUO Jianchun ZENG Bo ZHANG Yu HE Songgen 《Petroleum Exploration and Development》 CSCD 2021年第3期752-761,共10页
Shale samples of Silurian Longmaxi Formation in the Changning area of the Sichuan Basin, SW China, were selected to carry out scanning electron microscopy, CT imaging, high-pressure mercury injection, low-temperature ... Shale samples of Silurian Longmaxi Formation in the Changning area of the Sichuan Basin, SW China, were selected to carry out scanning electron microscopy, CT imaging, high-pressure mercury injection, low-temperature nitrogen adsorption and imbibition experiments to compare the hydration characteristics of montmorillonite and illite, analyze the main factors affecting the water block removal of shale, and reveal the mechanisms of pore structure evolution during shale hydration. The hydration characteristics of shale are closely related to the composition of clay minerals, the shale with high illite content is not susceptible to hydration and thus has limited room for pore structure improvement;the shale with high montmorillonite is susceptible to hydration expansion and thus has higher potential of pore structure improvement by stimulation;the shale with high illite content has stronger imbibition in the initial stage, but insufficient diffusion ability, and thus is likely to have water block;the shale with high montmorillonite content has weaker imbibition in the initial stage but better water diffusion, so water blocking in this kind of shale can be removed to some degree;the shale reservoir has an optimal hydration time, when it is best in physical properties, but hydration time too long would cause damage to the reservoir, and the shale with high illite content has a shorter optimal hydration time;inorganic cations can inhibit the hydration of clay minerals and have stronger inhibition to illite expansion, especially K^(+);for the reservoir with high content of montmorillonite, the cation content of fracturing fluid can be lowered to promote the shale hydration;fracturing fluid with high K^(+) content can be injected into reservoirs with high illite content to suppress hydration. 展开更多
关键词 SHALE clay minerals HYDRATION microscopic pore structure water block effect fracturing fluid diffusion optimal hydration time water block removal
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