Laser speckle imaging is a common technique to monitor blood flow.The fluctuations in speckle intensity can be related to the blood flow by calculating the speckle contrast,the ratio between the standard deviation of ...Laser speckle imaging is a common technique to monitor blood flow.The fluctuations in speckle intensity can be related to the blood flow by calculating the speckle contrast,the ratio between the standard deviation of speckle fluctuations and the average intensity.However,this simple statistic calculation is easily affected by motion artifacts.In this study,we applied sample entropy analysis instead of calculating standard deviations of the speckle fluctuations.Similar to the traditional method,sample entropy-based speckle contrast increases linearly with flow rate but was shown to be more immune to sudden movements during an upper arm occlusion test.展开更多
Objective To investigate pre- and postoperative changes of regional cerebral cortical blood flow in patients with cerebral arteriovenous malformation. Method Twenty-two adult patients with arteriovenous malformatio...Objective To investigate pre- and postoperative changes of regional cerebral cortical blood flow in patients with cerebral arteriovenous malformation. Method Twenty-two adult patients with arteriovenous malformation(AVM) were recruited into this study at Beijing Tiantan Hospital from September 2001 to May 2002. Eight patients had giant cerebral AVM and the other 14 had a small one. Cortical cerebral blood flow (CBF) was measured by laser Doppler flowmetry (LDF) before and after AVM resections. After surgery,the probe of LDF was implanted adjacent to the area of AVM and monitored for 24 hours.Results CBF increased significantly after the resection in all patients regardless of AVM size. In patients with small AVM,CBF returned to the baseline level within 4 hours,but in patients with giant AVM,CBF remained high even after 24 hours.Conclusions Monitoring CBF is helpful to understand pre- and postoperative changes of regional cortical CBF in patients with cerebral AVM.展开更多
基金GIST Research Institute(GRI)funded by GIST in 2019 and 2020Brain Research Program(2016M3C7A1905475)+1 种基金Basic Research Program(2018R1A2B6006797)through the National Research Foundation of Korea(NRF)funded by Ministry of Science and ICTKBRI basic research program through Korea Brain Research Institute funded by Ministry of Science and ICT(21-BR-03-05)。
文摘Laser speckle imaging is a common technique to monitor blood flow.The fluctuations in speckle intensity can be related to the blood flow by calculating the speckle contrast,the ratio between the standard deviation of speckle fluctuations and the average intensity.However,this simple statistic calculation is easily affected by motion artifacts.In this study,we applied sample entropy analysis instead of calculating standard deviations of the speckle fluctuations.Similar to the traditional method,sample entropy-based speckle contrast increases linearly with flow rate but was shown to be more immune to sudden movements during an upper arm occlusion test.
文摘Objective To investigate pre- and postoperative changes of regional cerebral cortical blood flow in patients with cerebral arteriovenous malformation. Method Twenty-two adult patients with arteriovenous malformation(AVM) were recruited into this study at Beijing Tiantan Hospital from September 2001 to May 2002. Eight patients had giant cerebral AVM and the other 14 had a small one. Cortical cerebral blood flow (CBF) was measured by laser Doppler flowmetry (LDF) before and after AVM resections. After surgery,the probe of LDF was implanted adjacent to the area of AVM and monitored for 24 hours.Results CBF increased significantly after the resection in all patients regardless of AVM size. In patients with small AVM,CBF returned to the baseline level within 4 hours,but in patients with giant AVM,CBF remained high even after 24 hours.Conclusions Monitoring CBF is helpful to understand pre- and postoperative changes of regional cortical CBF in patients with cerebral AVM.
