[Objectives]To explore the intervention effect of the representative formula of Xinrun Tongluo method,Liangxue Xiaofeng Powder,on the incidence of androgenic alopecia in the syndrome of blood heat and wind dryness.[Me...[Objectives]To explore the intervention effect of the representative formula of Xinrun Tongluo method,Liangxue Xiaofeng Powder,on the incidence of androgenic alopecia in the syndrome of blood heat and wind dryness.[Methods]A total of 72 patients with androgenic alopecia in Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine from October,2022 to June,2023 were randomly divided into a control group(36 cases,treated with Western medicine)and a treatment group(36 cases,treated with Chinese herbal formula+Western medicine).The short-term and long-term efficacy of the two groups of patients was compared.[Results]The hair microscopic signs and short-term and long-term efficacy of the treatment group were significantly better than those of the control group before and after treatment,with a statistically significant difference(P<0.05).[Conclusions]The representative formula of Xinrun Tongluo method is Liangxue Xiaofeng Powder,which has better clinical efficacy as an auxiliary Western medicine in the treatment of androgenic alopecia patients with blood heat and wind dryness syndrome,and is worthy of further promotion and application in clinical practice.展开更多
目的:观察中医实热证、虚热证两种不同证型之间与外周血 T 淋巴细胞亚群的变化差异。方法:采用间接免疫荧光法检测正常对照组30例、实热证患者27例、虚热证患者35例 T 细胞亚群的变化。结果:实热证、虚热证组患者与正常对照组相比,T 细...目的:观察中医实热证、虚热证两种不同证型之间与外周血 T 淋巴细胞亚群的变化差异。方法:采用间接免疫荧光法检测正常对照组30例、实热证患者27例、虚热证患者35例 T 细胞亚群的变化。结果:实热证、虚热证组患者与正常对照组相比,T 细胞亚群 CD_3、CD_4、CD_4/CD_8水平显著下降(P<0.05或 P<0.01),其中虚热证组 CD_4下降明显(P<0.05);而 CD_8水平升高只在实热证组患者有显著差异(P<0.01)。结论:虚热证、实热证两组患者都存在 T 细胞免疫功能紊乱。虚热证细胞免疫功能低下,而实热证虽然 T 淋巴细胞亚群亦低于正常人,但高于虚热证组。T 淋巴细胞亚群变化可为实热证、虚热证的客观化研究提供依据。展开更多
基金Supported by Suzhou Science and Technology Development Plan project (SKYD2022141)The Ninth Batch of Suzhou Gusu Health Key Talents Project (GSWS2022107).
文摘[Objectives]To explore the intervention effect of the representative formula of Xinrun Tongluo method,Liangxue Xiaofeng Powder,on the incidence of androgenic alopecia in the syndrome of blood heat and wind dryness.[Methods]A total of 72 patients with androgenic alopecia in Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine from October,2022 to June,2023 were randomly divided into a control group(36 cases,treated with Western medicine)and a treatment group(36 cases,treated with Chinese herbal formula+Western medicine).The short-term and long-term efficacy of the two groups of patients was compared.[Results]The hair microscopic signs and short-term and long-term efficacy of the treatment group were significantly better than those of the control group before and after treatment,with a statistically significant difference(P<0.05).[Conclusions]The representative formula of Xinrun Tongluo method is Liangxue Xiaofeng Powder,which has better clinical efficacy as an auxiliary Western medicine in the treatment of androgenic alopecia patients with blood heat and wind dryness syndrome,and is worthy of further promotion and application in clinical practice.
文摘目的:观察中医实热证、虚热证两种不同证型之间与外周血 T 淋巴细胞亚群的变化差异。方法:采用间接免疫荧光法检测正常对照组30例、实热证患者27例、虚热证患者35例 T 细胞亚群的变化。结果:实热证、虚热证组患者与正常对照组相比,T 细胞亚群 CD_3、CD_4、CD_4/CD_8水平显著下降(P<0.05或 P<0.01),其中虚热证组 CD_4下降明显(P<0.05);而 CD_8水平升高只在实热证组患者有显著差异(P<0.01)。结论:虚热证、实热证两组患者都存在 T 细胞免疫功能紊乱。虚热证细胞免疫功能低下,而实热证虽然 T 淋巴细胞亚群亦低于正常人,但高于虚热证组。T 淋巴细胞亚群变化可为实热证、虚热证的客观化研究提供依据。