The numerical simulation of the axial flow impeller blood pump NIVADIII is carried out by using a CFD multiphase flow model. The hydrodynamic performance of the pump and the flow field in the pump are analyzed, and th...The numerical simulation of the axial flow impeller blood pump NIVADIII is carried out by using a CFD multiphase flow model. The hydrodynamic performance of the pump and the flow field in the pump are analyzed, and the shear stress distribution is obtained. A hemolytic prediction model based on the shear stress is built based on the calculation results, and it can be used for qua- ntitative predictions of the hemolytic behavior of a blood pump. Hemolysis tests in vitro were performed 6 times with fresh bovine blood. At each time, the flow of the pump NIVADIII is 5 L/min and the outflow tract pressure is 100 mmHg. According to the tests, the plasma free hemoglobin （FHB） content and the hematocrit （HCT） are measured after 0 s, 0.5 s, 1 s, 1.5 s 4 s. At the end of each experiment Normal Index of Hemolysis （NIH） of NIVADIII is calculated. The average of NIH is 0.0055 g/100L, almost identi- cal with that obtained from the hemolytic prediction model. This method can be applied in the selection stage of a blood pump.展开更多
目的探讨离心式磁悬浮血泵内部流场和血液流动性能,为离心式磁悬浮血泵的结构设计提供重要依据。方法利用计算流体动力学分析软件,采用K-ε模型、动网格技术和用户自定义函数(user defined function,UDF)技术,开展离心式磁悬浮血泵内部...目的探讨离心式磁悬浮血泵内部流场和血液流动性能,为离心式磁悬浮血泵的结构设计提供重要依据。方法利用计算流体动力学分析软件,采用K-ε模型、动网格技术和用户自定义函数(user defined function,UDF)技术,开展离心式磁悬浮血泵内部流场的三维数值模拟,分析离心式磁悬浮血泵流道的压力、流速分布,探索血液流量、血液压力与叶轮转速的关系。结果该血泵叶轮转速在1800～2000 r/min时,进出口压差为110～120 mmHg,出口流量在4.69～5.28 L/min范围内变化,可以满足人体血液循环需求。结论离心式磁悬浮血泵叶轮参数对其流场特性具有较大影响,可通过对叶轮结构的优化改善血泵的血流特性,进而节约成本,缩短研发周期。展开更多
基金Project supported by the National High Technology Research and Development Program of China (863 Program,Grant No. 2007AA02Z439)The Key Disciplines Group Construction Project of Pudong Health Bureau of Shanghai (Grant No. PKzxkq2010-01)the Outstanding Leaders Training Program of Pudong Health Bureau of Shanghai (Grant No.PKR2011-01)
文摘The numerical simulation of the axial flow impeller blood pump NIVADIII is carried out by using a CFD multiphase flow model. The hydrodynamic performance of the pump and the flow field in the pump are analyzed, and the shear stress distribution is obtained. A hemolytic prediction model based on the shear stress is built based on the calculation results, and it can be used for qua- ntitative predictions of the hemolytic behavior of a blood pump. Hemolysis tests in vitro were performed 6 times with fresh bovine blood. At each time, the flow of the pump NIVADIII is 5 L/min and the outflow tract pressure is 100 mmHg. According to the tests, the plasma free hemoglobin （FHB） content and the hematocrit （HCT） are measured after 0 s, 0.5 s, 1 s, 1.5 s 4 s. At the end of each experiment Normal Index of Hemolysis （NIH） of NIVADIII is calculated. The average of NIH is 0.0055 g/100L, almost identi- cal with that obtained from the hemolytic prediction model. This method can be applied in the selection stage of a blood pump.
