The cost of environmental analysis is becoming astronomically high at the global scale. One of the major trends in the respective research activities is the development of biotesting methods. Such methods, in addition...The cost of environmental analysis is becoming astronomically high at the global scale. One of the major trends in the respective research activities is the development of biotesting methods. Such methods, in addition to ecotoxicology, are highly demanded for environmental monitoring and ecological standardization. The development of biotesting in toxicology, however, is limited to the ＂battery of tests＂ paradigm, while environmental monitoring and ecological standardization are based on the ＂uniformity of measurements＂ paradigm. A ＂reference bioindicator＂ is proposed to harmonize these approaches. A reference bioindicator serves for comparison of data obtained by different bioindicators. This method was approved for the state environmental control. Application of reference bioindicators makes analytical procedure substantially cheaper. It requires, however, thorough calibration in relation to specific environmental factors （such as temperature, photoperiod etc.） as well as to specific active agents and their combinations. This problem can be solved with the start-up of calibrating analytical centers and long-term study of the effects of spatiotemporal environmental factors in specific areas and for specific reference objects. This paper demonstrates long-term study results for the surface waters of Pavlovsk reservoir （Bashkortostan, Russia）.展开更多
There is little to no toxicity information regarding thousands of chemicals to which people are exposed daily.In fact,of the84,000 chemicals listed in the United States Toxic Substances Control Act Inventory,there is ...There is little to no toxicity information regarding thousands of chemicals to which people are exposed daily.In fact,of the84,000 chemicals listed in the United States Toxic Substances Control Act Inventory,there is limited information available on their effects on neural development（Betts,2010;US EPA,2015）.展开更多
文摘The cost of environmental analysis is becoming astronomically high at the global scale. One of the major trends in the respective research activities is the development of biotesting methods. Such methods, in addition to ecotoxicology, are highly demanded for environmental monitoring and ecological standardization. The development of biotesting in toxicology, however, is limited to the ＂battery of tests＂ paradigm, while environmental monitoring and ecological standardization are based on the ＂uniformity of measurements＂ paradigm. A ＂reference bioindicator＂ is proposed to harmonize these approaches. A reference bioindicator serves for comparison of data obtained by different bioindicators. This method was approved for the state environmental control. Application of reference bioindicators makes analytical procedure substantially cheaper. It requires, however, thorough calibration in relation to specific environmental factors （such as temperature, photoperiod etc.） as well as to specific active agents and their combinations. This problem can be solved with the start-up of calibrating analytical centers and long-term study of the effects of spatiotemporal environmental factors in specific areas and for specific reference objects. This paper demonstrates long-term study results for the surface waters of Pavlovsk reservoir （Bashkortostan, Russia）.
基金the Canada Research Chairs Program,the Canadian Institutes of Health Research,and the Natural Sciences and Engineering Research Council of Canada for their support
文摘There is little to no toxicity information regarding thousands of chemicals to which people are exposed daily.In fact,of the84,000 chemicals listed in the United States Toxic Substances Control Act Inventory,there is limited information available on their effects on neural development（Betts,2010;US EPA,2015）.
