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The role of hyaluronic acid in biomineralization
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作者 Zhen-Hua CHEN Xiu-Li REN +1 位作者 Hui-Hui ZHOU Xu-Dong LI 《Frontiers of Materials Science》 SCIE CSCD 2012年第4期283-296,共14页
Hyaluronic acid has been extensively investigated due to intrinsic properties of natural origin and strong ability to bind ions in water. Hyaluronic acid is an excellent crystal modifier because its abundant negativel... Hyaluronic acid has been extensively investigated due to intrinsic properties of natural origin and strong ability to bind ions in water. Hyaluronic acid is an excellent crystal modifier because its abundant negatively charged carboxyl groups can bind the cations protruding from the crystal lattice. In this review, we mainly present the latest work focus on the role of hyaluronic acid in controlling the crystallization, breaking the symmetry of crystal, and the surface funtionalization of nanocrystals. 展开更多
关键词 hyaluronic acid BIOMINERALIZATION crystal growth extracellular matrix bone and cartilage repair
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