Alzheimer’s disease(AD)is broadly defined by dementia and the presence of specific neuropathological features in the brain(amyloid plaques,neurofibrillary tangles(NFTs)and congophilic amyloid angiopathy).Howeve...Alzheimer’s disease(AD)is broadly defined by dementia and the presence of specific neuropathological features in the brain(amyloid plaques,neurofibrillary tangles(NFTs)and congophilic amyloid angiopathy).However,the rate of disease progression,type of cognitive impairment,and extent of neuropathology vary widely in patients with AD(Murray et al.,2011).展开更多
文摘Alzheimer’s disease(AD)is broadly defined by dementia and the presence of specific neuropathological features in the brain(amyloid plaques,neurofibrillary tangles(NFTs)and congophilic amyloid angiopathy).However,the rate of disease progression,type of cognitive impairment,and extent of neuropathology vary widely in patients with AD(Murray et al.,2011).