A novel evaluation term and a more reasonable criterion,which is described by a new parameter of brightness factor for active large mode area fiber design,are presented.The brightness factor evaluation method is based...A novel evaluation term and a more reasonable criterion,which is described by a new parameter of brightness factor for active large mode area fiber design,are presented.The brightness factor evaluation method is based on the transverse mode competition mechanism in fiber lasers and amplifiers.The brightness factor can be seen as a description of fiber general property since it can represent the output laser brightness of the fiber laser system and because of its ability to resist the nonlinear effect.A core-doped active large pitch fiber with a core diameter of 190 μm and a mode-field diameter of180 μm is designed by this method,and the designed fiber allows effective single-mode operation.展开更多
BACKGROUND Breast cancer morbidity has been increasing worldwide,but treatments are improving.The therapeutic response depends on the stage at which the disease is diagnosed.Therefore,early diagnosis has never been mo...BACKGROUND Breast cancer morbidity has been increasing worldwide,but treatments are improving.The therapeutic response depends on the stage at which the disease is diagnosed.Therefore,early diagnosis has never been more essential for successful treatment and a reduction in mortality rates.Radiology plays a pivotal role in cancer detection,and advances in ultrasound(US)palpation have shown promising results for breast cancer imaging.The addition of two-dimensional-shear wave elastography(2D-SWE)US in the routine breast imaging exam can increase early cancer detection and promote better surveillance.AIM To evaluate the clinical applications of 2D-SWE US in breast cancer detection and its combination with other imaging modalities.METHODS The 200 consecutive female patients aged 50-80 were examined to evaluate palpable breast lesions.All patients underwent mammography,bright mode(B-mode)US,and 2D-SWE followed by US-guided biopsy in two consecutive sessions.RESULTS Combining B-mode and shear wave US imaging with X-ray mammography revealed 100%of the suspicious lesions,resulting in greater sensitivity,specificity,and negative predictive value.The result improves compared to either B-mode or 2D-SWE alone(P=0.02).CONCLUSION Combining 2D-SWE with conventional US and X-ray techniques improves the chance of early cancer detection.Including 2D-SWE in regular breast imaging routines can reduce the need for biopsies and improve the chance of early cancer detection and survivability with the proper line of therapy.展开更多
基金supported by the National Natural Science Foundation of China(Grant No.61475081)
文摘A novel evaluation term and a more reasonable criterion,which is described by a new parameter of brightness factor for active large mode area fiber design,are presented.The brightness factor evaluation method is based on the transverse mode competition mechanism in fiber lasers and amplifiers.The brightness factor can be seen as a description of fiber general property since it can represent the output laser brightness of the fiber laser system and because of its ability to resist the nonlinear effect.A core-doped active large pitch fiber with a core diameter of 190 μm and a mode-field diameter of180 μm is designed by this method,and the designed fiber allows effective single-mode operation.
基金Supported by The European Union-Next Generation EU,through the National Recovery and Resilience Plan of the Republic of Bulgaria,No.BG-RRP-2.004-0008.
文摘BACKGROUND Breast cancer morbidity has been increasing worldwide,but treatments are improving.The therapeutic response depends on the stage at which the disease is diagnosed.Therefore,early diagnosis has never been more essential for successful treatment and a reduction in mortality rates.Radiology plays a pivotal role in cancer detection,and advances in ultrasound(US)palpation have shown promising results for breast cancer imaging.The addition of two-dimensional-shear wave elastography(2D-SWE)US in the routine breast imaging exam can increase early cancer detection and promote better surveillance.AIM To evaluate the clinical applications of 2D-SWE US in breast cancer detection and its combination with other imaging modalities.METHODS The 200 consecutive female patients aged 50-80 were examined to evaluate palpable breast lesions.All patients underwent mammography,bright mode(B-mode)US,and 2D-SWE followed by US-guided biopsy in two consecutive sessions.RESULTS Combining B-mode and shear wave US imaging with X-ray mammography revealed 100%of the suspicious lesions,resulting in greater sensitivity,specificity,and negative predictive value.The result improves compared to either B-mode or 2D-SWE alone(P=0.02).CONCLUSION Combining 2D-SWE with conventional US and X-ray techniques improves the chance of early cancer detection.Including 2D-SWE in regular breast imaging routines can reduce the need for biopsies and improve the chance of early cancer detection and survivability with the proper line of therapy.
基金National Natural Science Foundation of China(61501302,61465004,61765004,61764001,61464003)Natural Science Foundation of Guangxi Province(2018JJA170010)~~
