A novel alkenoic acid ester and a new benzophenone from Ranunculus ternatus

A novel alkenoic acid ester, （E）-4-hydroxy-dodec-2-enedioic acid-12-O-methyl ester and a new benzophenone, ethyl （S）-3-[2- （3,4-dihydroxybenzoyl）-4,5-dihydroxyphenyl]-2-hydroxypropanoate, together with a known compound, （E）-4-hydroxy-dodec-2- enedioic acids were isolated from the roots of Ranunculus ternatus. Their structures were elucidated by spectroscopic methods.

Degradation of benzophenone in aqueous solution by Mn-Fe-K modified ceramic honeycomb-catalyzed ozonation

Comparative studies of ozonation alone, ceramic honeycomb-catalyzed and Mn-Fe-K modified ceramic honeycomb catalyzed ozonation processes have been undertaken with benzophenone as the model organic pollutant. The experimental results showed that the presence of Mn-Fe-K modified ceramic honeycombs significantly increased the removal rate of benzophenone and TOC compared with that achieved by ozonation alone or ceramic honeycomb-catalyzed ozonation. The electron paramagnetic resonance （EPR） experiments verified that higher benzophenone removal rate was attribute to more hydroxyl radicals generated in the Mn-Fe-K modified ceramic honeycomb-catalyzed ozonation. Under the conditions of this experiment, the degradation rate of all the three ozonation processes are increasing with the amount of catalyst, temperature and value of pH increased in the solution. We also investigated the effects of different process of ozone addition, the optimum conditions for preparing catalyst and influence of the Mn-Fe-K modified ceramic honeycomb after multiple-repeated use.

A New Benzophenone from Securidaca inappendiculata

A new benzophenone, securiphenone A was isolated from the roots of Securidaca inappendiculata. Its structure was. determined as 2, 3-methylenedioxy-4-methoxybenzophenone by spectroscopie methods.

Photopolymerization induced by a benzophenone derivative photoinitiator

A benzophenone derivative photoinitiator, HBP-TDI-HQ-TDI-HBP （HTCTH）, was synthesized based on 4-hydroxy benzophenone （HBP）, toluene-2,4-diisocyanate （TDI） and hydroquinone （HQ）. HTCTH was a more effective photoinitiator which had longer wavelength absorption in the UV-vis absorption spectra than the low molecular counterpart benzophenone （BP）. It showed that both rate of polymerization （Rp） and final conversion （P） increased with increase of amine and HTCTH concentration in photopolymerization.

Photoinitiating Characteristics of Benzophenone Derivatives as Type II Macromolecular Photoinitiators Used for UV Curable Resins

Dodecyl-benzophenone（DBP） and hexadecoxyl-benzophenone（HDBP） as type 11 photoinitiators used for radical photopolymerization systems were synthesized by Friedel-Crafts reaction, and characterized by 1H NMR and FTIR spectroscopy. The UV-Vis absorption spectra of DBP and HDBP, propitious to photopolymerization under a commercial mercury UV bulb are centered at 345 and 335 nm, respectively. HDBP has higher extinction coefficient than DBP, but lower photoinitiating efficiency. Their photoinitiating performances for EB605, a bisphenol A epoxy acrylate with 40%（mass fraction） tripropyleneglycol diacrylate （TPGDA）, resin consisting of bisphenol A epoxy acrylate and tripropyleneglycol diacrylate in the presence of triethanolamine as a coinitiator were investigated by photo-differential scanning calorimetry（photo-DSC）. DBP initiates the curing of acrylate more efficiently than HDBP, showing higher photopolymerization rate and unsaturation conversion, resulted from the poor compatibility of HDBP with the resin. The photoinitiating activity of DBP to epoxy acrylate resin is even higher than that of BP at lower loadings.

Two new benzophenone glucosides from Cratoxylon cochinchinensis

Two new benzophenone glucosides were isolated from the 60% ethanol extract of the dried stems of Cratoxylum cochinchinense. The structures were elucidated as 3-O-β-D-glucopyranosyl-2＇,4,6＇-trihydroxy-benzophenone and 3-O-β-D-glucopyranosyl-2＇,5,6＇- trihydroxybenzophenone on the basis of spectral and chemical methods.

A new benzophenone C-glycoside from Polygala telephioides Willd

A new benzophenone C-glucoside,3’-C-[4-O-(5-hydroxyferuloyl)-β-D-glucopyranosyl]-2′,4′,6′-trihydroxy-3,4-dimethoxy-benzophenone, named telephenone D,was isolated from the whole plants of Polygala telephioides,and its structure was determined by analysis of spectroscopic data.

Novel triphenylamine-based two-photon absorption dyes including benzophenone parts

New two-photon absorption dyes including benzophenone parts, p-N,N-diphenylamino-p＇-phenacylstilbene （C1）, 4,4-di-（4- benzoylstyrene）yltriphenylamine （C2） and 4,4＇,4＇-tri（4-benzoylstyrene）yltriphenylamine （C3）, were synthesized and characterized by ^1H NMR and elemental analysis. The ratio of the molar extinction coefficients of compounds was approximately equal to the ratio of the branch amount of the compounds, namely, C1：C2：C3 was 1：2：3. Extremely high fluorescence quantum yields were detected for these compounds. These molecules exhibited obvious two-photon upconcerted fluorescence as excited by 800 nm Ti：sapphire femtosecond laser.

PHOTOINITIATED POLYMERIZATION BY ARYLIODONIUM SALT/BENZOPHENONE/TERTIARY AMINE BINARY PHOTOSENSITIZATION SYSTEM

A novel binary photosensitization system composed of benzophenone (BP)/diphenyliodonium chloride (DPIOC) Ariethylamine (TEA), exhibiting a good photoresponse at near UV and visible light regions, was used as the initiator for photopolymerization of MMA. The radical photogeneration in the binary system consists mainly of two parallel reactions, i. e. , BP/TEA photohydrogen-abstraction and DPIOC/TEA complex photodecomposition, but the latter is more active than the former. The results of comparative study indicate that the rate of polymerization induced by the binary system (BDT)is remarkably higher than those by the corresponding single systems The polymerization rates are proportional to [BP]^(0.16), [DPIOC]^(0.32) [TEA]^(0.45) and [MMA]. The mechanism is also discussed.

THE EFFECTS OF MAGNETIC FIELD ON GRAFT COPOLYMERIZATION OF METHYL METHACRYLATE ONTO POLYVINYL ALCOHOL IN THE PRESENCE OF BENZOPHENONE DURING UV IRRADIATION

The effects of magnetic field on the graft ratio and stereoregularity of grafts of PVA-g-MMA in the presence ofbenzophenone during UV irradiation are discussed. By means of IR, it was found that the graft ratio was increased with the increment of magnetic field strength. Furthermore, application of relative weak magnetic field of 0.4 Tesla had been shown to substantially enhance the stereo-regularity of graft copolymer. The maximum stereo-regularity appeared when the graft ratio approached to 85% with the magnetic field of 1.2 Tesla (T). The resistance to moisture and heat resistance of the grafted copolymer in the presence of magnetic field were also improved.

REACTION MECHANISM OF BENZOPHENONE-PHOTOINITIATED CROSSLINKING OF POLYETHYLENE

The radical intermediates, the crosslink microstructures, and the reaction mechanism of benzophenone (BP)-photoinitiated crosslinking of low-density polyethylene (LDPE) and model compounds (MD) have been reviewed in detail. The spin-trapping electron spin resonance (ESR) spectra obtained from the LDPE/BP systems with spin-trap agents show that two kinds of polymer radical intermediates are mainly formed: tertiary carbon and secondary carbon radicals. The spin-trapping ESR studies of MD/BP systems give further evidence that photocrosslinking reactions of PE predominantly take place a sites of tertiary carbon, secondary carbon, and especially allylic carbon when available. The high resolution C-13-NMR spectra obtained from LDPE and MD systems show that the crosslink microstructures have H- and Y-type links and that their concentrations are of the same order. The fluorescence, ESR, C-13 and H-1-NMR spectra from the PE and MD systems demonstrate that the main photoreduction product of BP (PPB) is benzpinacol formed by the recombination of two diphenylhydroxymethyl (K-.) radical intermediates. Two new PPB products: an isomer of benzpinacol with quinoid structure, 1-phenylhydroxymethylene-4-diphenylhydroxymethyl-2,5-cyclobexadiene and three kinds of alpha-alkyl-benzhydrols have been detected and identified. These results provide new experimental evidence for elucidating the reaction mechanism in the BP-photoinitiated crosslinking of polyethylene.

THE EFEFCT OF MAGNETIC FIELD ON POLYMERIZATION OF STYRENE IN THE PRESENCE OF POLYVINYL NAPHTHALENE AND POLYVINYL BENZOPHENONE

In the process of bulk photopolymerization of styrene initiated by AIBN decomposition polyvinyl benzophenone (PVB) can supply an effective cage for triplet-triplet energy transfer between PVB macromolecules and small molecules of AIBN to influence the molecular weight of polystyrene in weak magnetic field (less than 0.035T), that was different from the case of polyvinyl naphthalene (PVN) which supplied cages for this system only in the stronger magnetic field (more than 0.2 T) studies. It was found that in the same conditions, PVN could exert more tremendous influences on the bulk photopolymerizatiou system of styrene than PVB because in the stronger magnetic field the triplet PVN had much longer life time than PVB.

In vivo Anticancer Activities of Benzophenone Semicarbazone against Ehrlich Ascites Carcinoma Cells in Swiss Albino Mice

Objective Benzophenone semicarbazone(BSC) was synthesized and characterized to identify compounds with anticancer activities. Methods Anticancer activities were studied against Ehrlich Ascites Carcinoma(EAC) cells in Swiss albino mice by monitoring parameters such as tumor weight measurement,survival time of tumor bearing mice,tumor cell growth inhibition,and so on.Some hematological parameters,such as red blood cells,white blood cells,and hemoglobin content,were also measured. Results The results showed that BSC has a positive effect against EAC cells.An assessment was conducted by comparing these results with those obtained using the standard drug bleomycin. Conclusions The BSC compound can be considered as a potent anticancer agent.

PHOTOINDUCED CHARGE TRANSFER REACTION OF BENZOPHENONE WITH AMINE IN VESICLES

Photoinduced charge transfer reaction of benzophenone(BP) with, mine was carried out in the vesicles of dicetyldimethylammonium bromide (DCDAB) over wide ranges of amine concentration (0. 01～4. 0M). Linear plots of φ^(-1) vs. [TEA]^(-1) at low concentration of amine (<0.02M) and Φ^(-1) vs. [TEA]^(-2) at high concentration were obtained. Kinetic data demonstrate that the electron transfer is promoted significantly by DCDAB vesicles and proton transfer becomes more efficient at high Rmlne concentrations, leading to a decrease of Kd/Kr and increase of Kh/Ke. The kinetic expressions of photoreaction of BP bound to DCDAB bilayer are developed.

Toxicological Study Employing Repeated Doses of Garcinielliptone FC, a Polyisoprenylated-Benzophenone Isolated from Seed of Platonia Insignis Mart

The major constituent from the hexane extract of the seeds ofP. insignis is GFC （garcinielliptone FC）. Doses of 25, 50 and 75 mg/kg of GFC were aseptically suspended in 0.05% Tween 80 dissolved in 0.9% saline （vehicle） and orally administered for 30, 90 and 120 consecutive days to adult Swiss mice. In this work, the repeated oral administration, in animals of both sexes, demonstrates that this compound is not able to induce mortality and/or behavioral changes in adult mice. In addition, body weight gain, feed intake and disposal of excreta were not altered by the administration of this compound with repeated doses. Furthermore, no differences in weight and macroscopic structure of the brain, liver, kidney, lung, heart and spleen between groups of male and female adult mice were observed after treatment. During the periods of treatment, GFC produced no significant changes on haematological and biochemical parameters in male and female mice treated with all doses used. The aim of this study was to investigate the toxicological potential of GFC through behavioral, hematological, biochemical and morphological parameters in animals in order to ensure the safe use ofPlatonia insignis in folk medicine.

Analytical Determination of Benzophenone-3 in Sunscreen Preparations Using Boron-Doped Diamond Electrodes

A new electroanalytical procedure was developed for the determination of Benzophenone-3 (BENZO) in commercial sunscreen as the active ingredient. The procedure is based on the use of electrochemical methods as cyclic and square-wave voltammetry, with boron-doped diamond (BDD) electrodes. The reduction of BENZO in Britton-Robinson buffer (0.1 mol●L–1) using this type of electrode gives rise to one irreversible peak in –1.30 V (versus Ag/AgCl) in presence of cationic surfactant cetyltrimethylammonium bromide (CTABr). The proposed electrochemical method was successfully applied to the analysis of commercially available pharmaceutical preparations.

Beckmann重排反应的综合性实验设计与教学应用

Beckmann反应是含有羰基的醛、酮与羟胺反应生成有机肟,在催化剂作用下发生重排,在有机合成中具有重要意义。针对实验教学中有机肟Beckmann重排反应的实验原理直观性不足、反应机理佐证性欠缺等问题,通过二苯甲酮与盐酸羟胺反应生成二苯甲酮肟,多聚磷酸催化分子重排反应生成苯甲酰基苯胺为案例,交叉运用无机化学、分析化学、仪器分析的知识和实验技能,测定阶段产物和终产物的熔点、红外光谱、核磁共振谱并表征其结构,将宏观理化性质与微观结构相结合,解析和验证反应机理,达到Beckmann重排反应实验原理直观、反应机理佐证完善的结果,实验的综合设计与交叉创新提升了Beckmann重排实验的教学效果,并激发学生的创新意识。本文既可为肟类Beckmann重排反应的综合性、设计性实验提供借鉴,也可为教材及实验的改进提供有价值的参考。

具有抗紫外线功能的光固化涂料组合物的制备与性能研究

以羟基二苯甲酮、2-巯基苯并噁唑、芳基酰氯为原料,采用简单、温和的方法合成了新型二苯甲酮衍生物和含苯并噁唑的硫酯类衍生物,采用核磁氢谱1H NMR、核磁碳谱13C NMR和高分辨质谱HRMS等测试手段对目标化合物进行表征,并对其进行了光学性能测试,并用其制备了具有抗紫外线功能的光固化涂料。结果表明:两类衍生物能有效吸收220~350 nm的紫外光,与低聚物、单体相容性好,无气味。新合成的二苯甲酮衍生物作为光引发剂可使涂层固化时间大幅缩短到9 s,固化膜的外观、附着力和凝胶率相较于市售光引发剂BP有明显提高;硫酯类衍生物作为紫外吸收剂不仅能够增加光固化涂层的抗紫外线功能,且易于光固化涂料的制造、贮存。该组合物在罩面剂、油墨、胶黏剂等领域也有良好的应用前景。

光交联制备可拉伸有机半导体材料

有机半导体材料因具备良好的溶液加工性以及优异的电荷传输性能,在柔性器件中展现出广阔的应用前景。本文介绍了一种制备可拉伸半导体材料的方法。该方法利用二苯甲酮光引发将3,6-二噻吩-2-基-2,5-二氢吡咯并[3,4-c]吡咯-1,4-二酮基共轭聚合物(4Si)与聚二甲基硅氧烷进行光交联,研究了聚合物薄膜交联前后的电学性能和机械性能变化。结果显示,与未交联的4Si以及共混薄膜相比,交联薄膜的电学性能略微下降,但是机械性能得到了提升,起始裂纹应变由30%增加到50%。在100%的应变下,交联薄膜在平行应变方向上的迁移率为0.36 cm^(2)·V^(-1)·s^(-1),是初始迁移率的1.44倍。

山竹子茎叶化学成分的研究

目的:研究藤黄科藤黄属植物山竹子Garcinia multiflora Champ.ex Benth.茎叶的化学成分。方法:运用硅胶、HPLC等多种色谱技术对山竹子茎叶的醇提物进行分离纯化,根据理化性质和波谱数据鉴定化合物的结构。结果:从山竹子茎叶中分离得到14个化合物,分别鉴定为:1,3,7-三羟基呫吨酮(1)、1,3,6,7-四羟基呫吨酮(2)、1,6-二羟基-3,5,7-三甲氧基呫吨酮(3)、GDPPH-1(4)、香橙素(5)、eriodictyol(6)、7,5,4′-三羟基黄酮(7)、4,6,4′-三羟基-2,3′-二甲氧基-3-异戊烯基二苯甲酮(8)、garcicowin D(9)、30-epi-cambogin(10)、garcimultiflorone H(11)、garcinol(12)、1-丙酮,1-(3,4-二羟基-5-甲氧基苯基)(13)、loliolide(14)。结论:其中,化合物1、4~6、9、11~14为首次从该植物中分离得到。