Treatment of potassium bromodifluoroacetate(1)with alkyl halides in the presence of copper,iodide and potassium fluoride in DMF at 85—90℃ for 3—5h gavethe trifluoromethylated derivatives in moderate to high yields.
基金Project supported by the National Natural Science Foundation of China.
文摘Treatment of potassium bromodifluoroacetate(1)with alkyl halides in the presence of copper,iodide and potassium fluoride in DMF at 85—90℃ for 3—5h gavethe trifluoromethylated derivatives in moderate to high yields.
