Phosphine oxide-Sc(OTf)3 catalyzed regio-and enantioselective bromoaminocyclization of tri-substituted allyl N-tosylcarbamates is described. Awide variety of optically active tertiary 5-bromo-1,3-oxazinan-2-ones can b...Phosphine oxide-Sc(OTf)3 catalyzed regio-and enantioselective bromoaminocyclization of tri-substituted allyl N-tosylcarbamates is described. Awide variety of optically active tertiary 5-bromo-1,3-oxazinan-2-ones can be obtained with high regio-and enantioselectivity.展开更多
基金supported by the National Natural Science Foundation of China (21632005, 21172221)
文摘Phosphine oxide-Sc(OTf)3 catalyzed regio-and enantioselective bromoaminocyclization of tri-substituted allyl N-tosylcarbamates is described. Awide variety of optically active tertiary 5-bromo-1,3-oxazinan-2-ones can be obtained with high regio-and enantioselectivity.
