The Navier-Stokes equations for the two-dimensional incompressible flow are used to investigate the effects of the Reynolds number and the Weber number on the behavior of interface between liquid gas shear flow. In th...The Navier-Stokes equations for the two-dimensional incompressible flow are used to investigate the effects of the Reynolds number and the Weber number on the behavior of interface between liquid gas shear flow. In the present study, the density ratios are fixed at approximately 10^0-10^3. The interface between the two phases is resolved using the level-set approach. The Reynolds number and the Weber number, based on the gas, are selected as 400-10000 and 40-5000, respectively. In the past, simulations reappeared the amplitude of interface growth predicted by viscous Orr-Sommerfeld linear theory, verifying the applicability and accuracy of the numerical method over a wide range of density and viscosity ratios; now, the simulations show that the nonlinear development of ligament elongated structures and resulted in the subsequent breakup of the heavier fluid into drops.展开更多
The electrochemical behavior of ionizable drugs (Amitriptyline, Diphenhydramine and Trihexyphene- dyl) at the water/1,2-dichloroethane interface with the phase volume ratio (r = Vo/Vw) equal to 1 are investigated by c...The electrochemical behavior of ionizable drugs (Amitriptyline, Diphenhydramine and Trihexyphene- dyl) at the water/1,2-dichloroethane interface with the phase volume ratio (r = Vo/Vw) equal to 1 are investigated by cyclic voltammetry. The system is composed of an aqueous droplet supported at an Ag/AgCl disk electrode and it was covered with an organic solution. In this manner, a conventional three-electrode potentiostat can be used to study the ioni-zable drugs transfer process at a liquid/liquid interface. Physicochemical parameters such as the formal transfer potential, the Gibbs energy of transfer and the standard par-tition coefficients of the ionized forms of these drugs can be evaluated from cyclic voltammograms obtained. The ob-tained results have been summarized in ionic partition dia-grams, which are a useful tool for predicting and interpret-ing the transfer mechanisms of ionizable drugs at the liq-uid/liquid interfaces and biological membranes.展开更多
The electrochemical behavior of ionizable drugs (Amitriptyline, Diphenhydramine and Trihexyphene- dyl) at the water/1,2-dichloroethane interface with the phase volume ratio (r = Vo/Vw) equal to 1 are investigated by c...The electrochemical behavior of ionizable drugs (Amitriptyline, Diphenhydramine and Trihexyphene- dyl) at the water/1,2-dichloroethane interface with the phase volume ratio (r = Vo/Vw) equal to 1 are investigated by cyclic voltammetry. The system is composed of an aqueous droplet supported at an Ag/AgCl disk electrode and it was covered with an organic solution. In this manner, a conventional three-electrode potentiostat can be used to study the ionizable drugs transfer process at a liquid/liquid interface. Physicochemical parameters such as the formal transfer potential, the Gibbs energy of transfer and the standard partition coefficients of the ionized forms of these drugs can be evaluated from cyclic voltammograms obtained. The obtained results have been summarized in ionic partition diagrams, which are a useful tool for predicting and interpreting the transfer mechanisms of ionizable drugs at the liquid/liquid interfaces and biological membranes.展开更多
The precipitation dynamics of γ’(L1-NiAl)phase and composition interfacial width between γ(fcc Ni)and γ’ phase were investigated using the phase field simulation linking with CALPHAD method.The coarsening rate an...The precipitation dynamics of γ’(L1-NiAl)phase and composition interfacial width between γ(fcc Ni)and γ’ phase were investigated using the phase field simulation linking with CALPHAD method.The coarsening rate and particle size distribution(PSD) of γ’ phase,the temporal composition interfacial width of γ/γ’ in Ni-17 at% Al alloy aged at 923,973 and 1023 K were clarified.As the aging temperature increases,the morphology of γ’ phase changes from the interconnected rectangle shape to the separated cuboidal shape.The average particle radius(<r>) of γ’ phase at coarsening stage follows <r> ∞t^(n) with the exponents n=0.21,0.23 and 0.26,respectively.The peak values of simulated PSDs at 923 K are less than the value calculated by the Lifshitz-Slyozov-Wagner(LSW) model,and the width of simulated PSD increases at later stage of precipitation.The normalized radius(r/<r>)which corresponds to the peak value of PSD moves from1.1 to 1.0 as the aging temperature increases from 923 to1023 K,and they are smaller than that of LSW model.The composition interfacial width decreases as the aging progresses and increases as the aging temperature increases.展开更多
基金Project supported by the National Natural Science Foundation of China (Grant No:50371049)Shanghai Leading Academic Discipline Project (Grant No:Y0103)
文摘The Navier-Stokes equations for the two-dimensional incompressible flow are used to investigate the effects of the Reynolds number and the Weber number on the behavior of interface between liquid gas shear flow. In the present study, the density ratios are fixed at approximately 10^0-10^3. The interface between the two phases is resolved using the level-set approach. The Reynolds number and the Weber number, based on the gas, are selected as 400-10000 and 40-5000, respectively. In the past, simulations reappeared the amplitude of interface growth predicted by viscous Orr-Sommerfeld linear theory, verifying the applicability and accuracy of the numerical method over a wide range of density and viscosity ratios; now, the simulations show that the nonlinear development of ligament elongated structures and resulted in the subsequent breakup of the heavier fluid into drops.
文摘The electrochemical behavior of ionizable drugs (Amitriptyline, Diphenhydramine and Trihexyphene- dyl) at the water/1,2-dichloroethane interface with the phase volume ratio (r = Vo/Vw) equal to 1 are investigated by cyclic voltammetry. The system is composed of an aqueous droplet supported at an Ag/AgCl disk electrode and it was covered with an organic solution. In this manner, a conventional three-electrode potentiostat can be used to study the ioni-zable drugs transfer process at a liquid/liquid interface. Physicochemical parameters such as the formal transfer potential, the Gibbs energy of transfer and the standard par-tition coefficients of the ionized forms of these drugs can be evaluated from cyclic voltammograms obtained. The ob-tained results have been summarized in ionic partition dia-grams, which are a useful tool for predicting and interpret-ing the transfer mechanisms of ionizable drugs at the liq-uid/liquid interfaces and biological membranes.
文摘The electrochemical behavior of ionizable drugs (Amitriptyline, Diphenhydramine and Trihexyphene- dyl) at the water/1,2-dichloroethane interface with the phase volume ratio (r = Vo/Vw) equal to 1 are investigated by cyclic voltammetry. The system is composed of an aqueous droplet supported at an Ag/AgCl disk electrode and it was covered with an organic solution. In this manner, a conventional three-electrode potentiostat can be used to study the ionizable drugs transfer process at a liquid/liquid interface. Physicochemical parameters such as the formal transfer potential, the Gibbs energy of transfer and the standard partition coefficients of the ionized forms of these drugs can be evaluated from cyclic voltammograms obtained. The obtained results have been summarized in ionic partition diagrams, which are a useful tool for predicting and interpreting the transfer mechanisms of ionizable drugs at the liquid/liquid interfaces and biological membranes.
基金financially supported by the National Natural Science Foundation of China (No.51571122)the Fundamental Research Funds for the Central Universities (No. 30920130121012)the Graduate Innovation Project of Jiangsu Province (No.SJLX_0157)。
文摘The precipitation dynamics of γ’(L1-NiAl)phase and composition interfacial width between γ(fcc Ni)and γ’ phase were investigated using the phase field simulation linking with CALPHAD method.The coarsening rate and particle size distribution(PSD) of γ’ phase,the temporal composition interfacial width of γ/γ’ in Ni-17 at% Al alloy aged at 923,973 and 1023 K were clarified.As the aging temperature increases,the morphology of γ’ phase changes from the interconnected rectangle shape to the separated cuboidal shape.The average particle radius(<r>) of γ’ phase at coarsening stage follows <r> ∞t^(n) with the exponents n=0.21,0.23 and 0.26,respectively.The peak values of simulated PSDs at 923 K are less than the value calculated by the Lifshitz-Slyozov-Wagner(LSW) model,and the width of simulated PSD increases at later stage of precipitation.The normalized radius(r/<r>)which corresponds to the peak value of PSD moves from1.1 to 1.0 as the aging temperature increases from 923 to1023 K,and they are smaller than that of LSW model.The composition interfacial width decreases as the aging progresses and increases as the aging temperature increases.
