目的：探讨集束化护理干预（Bundlers of Nursing Care）模式在癫痫专科病房临床应用的效果。方法：选择238例患者为本研究的研究对象。按照入院时间不同对患者采取不同的护理模式。将112例于2012年7月-2013年6月入院的患者设为对照组,...目的：探讨集束化护理干预（Bundlers of Nursing Care）模式在癫痫专科病房临床应用的效果。方法：选择238例患者为本研究的研究对象。按照入院时间不同对患者采取不同的护理模式。将112例于2012年7月-2013年6月入院的患者设为对照组,采取传统常规护理模式;将126例2013年7月-2014年6月期间入院的患者设为观察组,采取集束化护理模式。对比两组效果及调查结果。结果：观察组护士满意度明显高于对照组,两组差异具有显著统计学意义（P〈0.001）。观察组健康教育知识掌握率明显高于对照组,差异有统计学意义（P〈0.01）。观察组护理投诉、不良事件发生率明显低于对照组,差异有统计学意义（P〈0.05）。结论：神经外科设立癫痫专科病房并进行集束化护理干预,有助于提高医疗服务质量,减少护患纠纷。展开更多
为改进打捆机结构设计,应用ADAMS软件对打捆机关键部件压缩板进行运行载荷及其受力载荷分析,得到有限元静力学与模态分析建立边界条件;利用ANSYS软件分析压缩板的静力学及模态,获得最大载荷工况下的最大变形、最大应力、最大剪切应力、...为改进打捆机结构设计,应用ADAMS软件对打捆机关键部件压缩板进行运行载荷及其受力载荷分析,得到有限元静力学与模态分析建立边界条件;利用ANSYS软件分析压缩板的静力学及模态,获得最大载荷工况下的最大变形、最大应力、最大剪切应力、弹性应变、应变能密度及前20阶固有频率模态。结果表明:在压缩板载荷轴的两端处最大面载荷为490 k N的工况下,其强度、刚度均满足设计要求;根据获得压缩板的固有频率及振型的相应变化规律,打捆机压缩仓的主要工作部件不会发生共振现象。展开更多
Formins have been paid much attention for their potent nucleating activity. However, the connection between the in vivo functions of AtFHs （Arabidopsis thaliana formin homologs） and their effects on actin organizati...Formins have been paid much attention for their potent nucleating activity. However, the connection between the in vivo functions of AtFHs （Arabidopsis thaliana formin homologs） and their effects on actin organization is poorly understood, in this study, we characterized the bundling activity of AtFH8 in vitro and in vivo. Biochemical analysis showed that AtFH8（FH1FH2） could form dimers and bundle preformed actin filaments or induce stellar structures during actin polymerization. Expression of truncated forms of AtFH8 and immunolocalization analysis showed that AtFH8 localized primarily to nuclear envelope in interphase and to the new cell wall after cytokinesis, depending primarily on its N-terminal transmembrane domain. GUS histochemical staining showed AtFH8 was predominantly expressed in Arabidopsis root meristem, vasculature, and outgrowth points of lateral roots. The primary root growth and lateral root initiation of atfh8 could be decreased by latrunculin B （LatB）. Analysis of the number of dividing cells in Arabidopsis root tips showed that much fewer dividing cells in Lat B-treated atfh8 plants than wild-type plants, which indicates that AtFH8 was involved in cell division. Actin cytoskeleton in root meristem of atfh8-1 was more sensitive to LatB treatment than that of wild-type. Altogether, our results indicate that AtFH8 is an actin filament nucleator and bundler that functions in cell division and root development.展开更多
文摘目的：探讨集束化护理干预（Bundlers of Nursing Care）模式在癫痫专科病房临床应用的效果。方法：选择238例患者为本研究的研究对象。按照入院时间不同对患者采取不同的护理模式。将112例于2012年7月-2013年6月入院的患者设为对照组,采取传统常规护理模式;将126例2013年7月-2014年6月期间入院的患者设为观察组,采取集束化护理模式。对比两组效果及调查结果。结果：观察组护士满意度明显高于对照组,两组差异具有显著统计学意义（P〈0.001）。观察组健康教育知识掌握率明显高于对照组,差异有统计学意义（P〈0.01）。观察组护理投诉、不良事件发生率明显低于对照组,差异有统计学意义（P〈0.05）。结论：神经外科设立癫痫专科病房并进行集束化护理干预,有助于提高医疗服务质量,减少护患纠纷。
文摘为改进打捆机结构设计,应用ADAMS软件对打捆机关键部件压缩板进行运行载荷及其受力载荷分析,得到有限元静力学与模态分析建立边界条件;利用ANSYS软件分析压缩板的静力学及模态,获得最大载荷工况下的最大变形、最大应力、最大剪切应力、弹性应变、应变能密度及前20阶固有频率模态。结果表明:在压缩板载荷轴的两端处最大面载荷为490 k N的工况下,其强度、刚度均满足设计要求;根据获得压缩板的固有频率及振型的相应变化规律,打捆机压缩仓的主要工作部件不会发生共振现象。
文摘Formins have been paid much attention for their potent nucleating activity. However, the connection between the in vivo functions of AtFHs （Arabidopsis thaliana formin homologs） and their effects on actin organization is poorly understood, in this study, we characterized the bundling activity of AtFH8 in vitro and in vivo. Biochemical analysis showed that AtFH8（FH1FH2） could form dimers and bundle preformed actin filaments or induce stellar structures during actin polymerization. Expression of truncated forms of AtFH8 and immunolocalization analysis showed that AtFH8 localized primarily to nuclear envelope in interphase and to the new cell wall after cytokinesis, depending primarily on its N-terminal transmembrane domain. GUS histochemical staining showed AtFH8 was predominantly expressed in Arabidopsis root meristem, vasculature, and outgrowth points of lateral roots. The primary root growth and lateral root initiation of atfh8 could be decreased by latrunculin B （LatB）. Analysis of the number of dividing cells in Arabidopsis root tips showed that much fewer dividing cells in Lat B-treated atfh8 plants than wild-type plants, which indicates that AtFH8 was involved in cell division. Actin cytoskeleton in root meristem of atfh8-1 was more sensitive to LatB treatment than that of wild-type. Altogether, our results indicate that AtFH8 is an actin filament nucleator and bundler that functions in cell division and root development.
