Objective Benzyl butyl phthalate （BBP） is a plasticizer used in food contact materials. Dietary exposure to BBP might lead to reproduction and developmental damages to human. The present paper was aimed to assess th...Objective Benzyl butyl phthalate （BBP） is a plasticizer used in food contact materials. Dietary exposure to BBP might lead to reproduction and developmental damages to human. The present paper was aimed to assess the health risk of BBP dietary exposure in Chinese population. Methods The BBP contents were detected in 7409 food samples from 25 food categories by gas chromatography-mass spectrometry operated in selected ion monitoring （SIM） mode. The dietary exposures of BBP in different age and sex groups were estimated by combining the content data with food consumption data derived from 2002 China National Nutrient and Health Survey, and evaluated according to the tolerable daily intake （TDI） of BBP established by European Food safety Agency. Results It was found that BBP was undetectable in most samples and the highest level was 2.69 mg/kg detected in a vegetable oil sample. The average dietary exposure of BBP in people aged 〉2 years was 2.03μg/kg bw per day and the highest average exposure was found in 2-6 years old children （1.98μg/kg bw per day）. The BBP exposure in 7-12 months old children excessed 10% of tolerable daily intake （TDI） in worst scenario. Conclusion The health risk of BBP dietary exposure in Chinese population is low and, considering BBP alone, there is no safety concern.展开更多
基金supported by China's Ministry of Science&Technology(No.2014ZX09304307)
文摘Objective Benzyl butyl phthalate （BBP） is a plasticizer used in food contact materials. Dietary exposure to BBP might lead to reproduction and developmental damages to human. The present paper was aimed to assess the health risk of BBP dietary exposure in Chinese population. Methods The BBP contents were detected in 7409 food samples from 25 food categories by gas chromatography-mass spectrometry operated in selected ion monitoring （SIM） mode. The dietary exposures of BBP in different age and sex groups were estimated by combining the content data with food consumption data derived from 2002 China National Nutrient and Health Survey, and evaluated according to the tolerable daily intake （TDI） of BBP established by European Food safety Agency. Results It was found that BBP was undetectable in most samples and the highest level was 2.69 mg/kg detected in a vegetable oil sample. The average dietary exposure of BBP in people aged 〉2 years was 2.03μg/kg bw per day and the highest average exposure was found in 2-6 years old children （1.98μg/kg bw per day）. The BBP exposure in 7-12 months old children excessed 10% of tolerable daily intake （TDI） in worst scenario. Conclusion The health risk of BBP dietary exposure in Chinese population is low and, considering BBP alone, there is no safety concern.
