Association between Mental Health Literacy and Workplace Well-Being of Chinese Grassroots Civil Servants:The Chain Mediating Effects of Regulatory Emotional Self-Efficacy and Resilience

This study aimed to investigate the relationship between mental health literacy(MHL)and workplace well-being(WWB)of Chinese grassroots civil servants,with regulatory emotional self-efficacy(RESE)and resilience as mediating variables.A questionnaire survey was conducted among Chinese grassroots civil servants,with a valid sample size of 2673 after excluding missing values and conducting relevant data processing.The PROCESS was used to examine the relationship between MHL,RESE,resilience,and WWB.The study found that MHL among grassroots civil servants was positively and significantly correlated with WWB(r=0.73,p<0.01).RESE partially mediated the relationship between MHL and WWB(β=0.25,95%CI[0.22,0.28]).Resilience partially mediated the relationship between MHL and WWB(β=0.22,95%CI[0.19,0.26]).MHL had a positive effect on WWB through the chain mediating effect of RESE and resilience(β=0.05,95%CI[0.03,0.07]).There is a close relationship between MHL and WWB,where Chinese grassroots civil servants with higher levels of MHL can develop stronger RESE and resilience,leading to higher WWB.The results of this study remind organizational institutions of Chinese grassroots civil servants that enhancing MHL,RESE,and resilience is an important pathway to promoting their WWB.

CacyBP/SIP基因沉默对人乳腺癌MDA-MB-231细胞凋亡的影响

目的观察干扰小RNA(siRNA)介导的Cacy BP/SIP基因沉默对人乳腺癌MDA-MB-231细胞凋亡的影响。方法化学合成Cacy BP/SIP基因序列特异性siRNA(Cacy BP/SIP siRNA),采用脂质体法转染siRNA至MDA-MB-231细胞(Cacy BP/SIP siRNA组),MTT比色法检测细胞增殖,流式细胞仪检测细胞凋亡率。Realtime PCR和Western blotting检测MDA-MB-231细胞内Bcl-2、Bax、Caspase-3 mRNA及蛋白的表达。另设阴性对照组和空白对照组。结果与阴性对照组和空白对照组比较,Cacy BP/SIP siRNA组MDA-MB-231细胞增殖能力显著下降(P<0.05),细胞凋亡率显著增高(P<0.05)。Caspase-3和Bax mRNA及蛋白表达上调(P<0.05),Bcl-2 mRNA及蛋白表达下调(P<0.05)。结论靶向沉默乳腺癌MDA-MB-231细胞中Cacy BP/SIP基因表达后,可以抑制乳腺癌细胞增殖并诱导凋亡,其作用可能通过下调Bcl-2表达,上调Caspase-3和Bax表达发挥诱导细胞凋亡的作用。

Effects of College Students’ Perceived Stress on Anxiety in the Time of COVID-19: The Chain Mediation Role of Psychological Resilience and Regulatory Emotional Self-Efficacy

COVID-19 has changed the way of learning and life of college students.The purpose is to explore the relationship between perceived stress and anxiety,and the mediating effect of resilience and regulatory emotional self-efficacy in college students during COVID-19.309 students from three colleges were selected as research participants(average age 19.79±1.11 years).SPSS was used to measure the correlation between variables.Amos was used to test the path coefficient and mediating effect of the hypothetical model.The results show that:Firstly,perceived stress has a significantly and positively predictive effect on anxiety.Secondly,psychological resilience and regu-latory emotional self-efficacy independently played a significant and partially mediating effect between perceived stress and anxiety.Among them,perceived stress had a negative predictive effect on psychological resilience and regulatory emotional self-efficacy.Psychological resilience and regulatory emotional self-efficacy had a negative predictive effect on anxiety.Thirdly,psychological resilience and regulatory emotional self-efficacy play a chain mediation role between psychological stress and anxiety.Regulatory emotional self-efficacy cannot only directly predict the level of anxiety,but also indirectly predict the level of anxiety by regulating psychological resilience.This study reveals the relationship between college students’perceived stress and anxiety,and the mediating effect of psychological resilience and regulatory emotional self-efficacy in the new time of COVID-19.The chain mediation role of psychological resilience and regulatory emotional self-efficacy reminds college mental health educators that improving students’regulatory emotional self-efficacy is an important way to promote students’mental health.

静脉输入不同浓度利多卡因的药效学研究

本研究应用微机辅助输液泵（ＣＡＣＩ）装置持续静脉输入利多卡因维持恒定目标血药浓度（Ｃｔ），观察不同Ｃｔ利多卡因静脉复合麻醉的临床药效学。输入利多卡因的同时吸入一定浓度的安氟醚，测定安氟醚的ＭＡＣ，从而推算出静滴利多卡因的麻醉效能。结果表明，利多卡因Ｃｔ３μｇ／ｍｌ时可减少安氟醚ＭＡＣ１１．９％；Ｃｔ５μｇ／ｍｌ时减少２３．８％；Ｃｔ５μｇ／ｍｌ复合芬太尼（１～２μｇ／ｋｇ）减少４２．９％；Ｃｔ３μｇ／ｍｌ复合芬太尼（１～２μｇ／ｌｇ）减少２８．６％。上述各组的麻醉深度对血流动力学影响较小，所测得ＭＡＣ相当于ＭＡＣ－ＢＡＲ。结果提示利多卡因Ｃｔ３～５μｇ／ｍｌ复合小剂量芬太尼对循环影响小、临床麻醉效能高、苏醒彻底、苏醒期安静。应用ＣＡＣＩ输入利多卡因安全、可靠、值得推广应用。

The effectiveness of a high-fidelity teaching simulation based on an NLN/Jeffries simulation in the nursing education theoretical framework and its influencing factors

Objective： To investigate the effectiveness of a high-fidelity teaching simulation based on an NLN/Jeffries simulation in the nursing education theoretical framework and its influencing factors. Methods： A high-fidelity teaching simulation on clinical nursing practices using intelligent human analogues was conducted with 200 students, and The Simulation Design Scale, and the Student Satisfaction and Self-Confidence in Learning Scale developed by the National League for Nursing were used to evaluate the training effectiveness and its influencing factors. Results： For the high-fidelity teaching simulation, students gave scores of 4.36± 0.54 points for satisfaction and 4.33 ± 0.46 points for Self-Confidence. The students highly rated the five dimensions of teaching design, i.e., teaching objectives/information, assistance/support for students, problem solving, guided feedback, and fidelity. The teaching design was closely correlated with the satisfaction of the high-fidelity teaching simulation and self-efficacy, and the dimensions of teaching objectives/informa- tion and assistance/support for students were particularly strong predictors of teaching effectiveness. Conclusions： A high-fidelity teaching simulation based on Jeffries＇ theoretical framework improved student satisfaction with the simulation and their Self-Confidence. In planning simulations, teachers should take into account five characteristics, i.e., teaching objectives/information on simulation education, assistance/support for students, problem solving, guided reflection, and fidelity, to achieve better teaching effectiveness.

Multitasking Behavior and Perceptions of Academic Performance in University Business Students in Mexico during the COVID-19 Pandemic

The current study measures the influence of multitasking behavior and self-efficacy for self-regulated learning(SESRL)on perceptions of academic performance and views in university students during the COVID-19 pan-demic in Mexico.264 university students fulfilled an online questionnaire.It was observed that multitasking beha-vior negatively influences SESRL(-0.203),while SESRL showed a positive influence of 0.537 on perceptions of academic performance,and multitasking behavior had an influence of-0.097 on the perception of academic per-formance.Cronbach’s alpha and Average Variance Extracted values were 0.809 and 0.577(multitasking behavior),0.819 and 0.626(SESRL),0.873 and 0.725(perceptions of academic performance),respectively.The results of the bootstrapping test showed that the path coefficients were significant.The study outcomes can support new plans in universities to ensure the best academic outcomes.Our study showed evidence of the COVID-19 impact on education behavior.This study’s novelty is based on using the partial least square structural equation modeling(PLS-SEM)technique to evaluate these variables.

Study of Applying Cognitive Linguistic Theory into Japanese Grammar Teaching——Taking Causative Sentence as an Example

The traditional Japanese grammar teaching often only pays attention to the interpretation of syntax and the integrity of grammar structure. This violates the cultivation of communicative competence, and is not in conformity with the society’s requirements of applied foreign language talents. Cognitive linguistics theory, which links language form with semantic concept, reveals the internal relation of man’s thinking and language. If we can subtly apply cognitive linguistic theory into Japanese grammar teaching to explore the cognitive process in the speakers’ brain while expressing, we can get a good understanding of diffi cult points and “special case”. This paper explores the introductory methods and efficacy of the cognitive linguistics theory applied in Japanese grammar teaching method, by lecturing causative sentences an example.

ACECM取向支架--软骨组织工程的新时代

关节软骨是无血管结构并且受伤的软骨不能自我修复,从而导致关节疼痛和关节失稳,并最终导致关节置换。因此,研究者把软骨组织的再生和修复工程作为一种很有前途的方法。在本文中,我们回顾了的正常结构和功能的关节软骨,软骨损伤的修复方法,软骨组织工程的临床技术的历史。最后,我们得出的结论是ACECM取向支架移植技术可能会取代基质诱导的自体软骨细胞移植(MACI),越来越多的患者会从这项技术中受益。

全国第21届计算机技术与应用(CACIS·2010)暨第2届安全关键技术与应用学术会议征文通知(第一轮)

中国仪器仪表学会和中国系统仿真学会长期致力于计算机科学与技术的研究与应用推广工作,尤其致力于计算机技术在仪器仪表、复杂系统、建模仿真、安全关键中的应用,CACIS工作年会已成为全国信息学科相关专业互相渗透和交流的重要平台。全国第21届计算机技术与应用学术会议(CACIS·2010)暨将于2010年8月20-24日在上海海事大学举行。

宫颈癌组织中CACI的表达变化及其与宫颈HR-HPV感染的关系

目的:分析宫颈癌组织中CACI的表达变化与宫颈HR-HPV感染的关系。方法:选取2018年5月-2020年5月行HR-HPV检测及宫颈活检的患者115例,取病理科保存的患者宫颈组织标本进行观察。其中CINⅠ级标本37例,设为B组;CINⅡ~Ⅲ级标本33例,设为C组;宫颈癌标本45例,设为D组;另选择同期因子宫肌瘤行全子宫切除且证实为慢性宫颈炎组织患者26例,设为A组。行免疫组化法检测四组CACI表达,分析宫颈癌患者病理特征与CACI表达的关系。结果:A组、B组宫颈组织中CACI阳性率及HR-HPV阳性率比较,差异无统计学意义(P>0.05);B组、C组、D组宫颈组织CACI阳性率及HR-HPV阳性率依次升高,差异有统计学意义(P<0.05)。CACI阳性表达与病理分期、分化程度相关,差异有统计学意义(P<0.05);与患者年龄、淋巴结转移情况无关,差异无统计学意义(P>0.05)。结论:宫颈组织中CACI与HR-HPV均可导致宫颈癌发生,而宫颈癌组织中CACI高表达会加重病情严重程度。

全国第18届计算机技术与应用(CACIS·2007)学术会议征文通知(第一轮)

中国仪器仪表学会和中国系统仿真学会长期致力于计算机科学与技术的研究与应用推广工作,尤其致力于计算机技术在仪器仪表、复杂系统、建模仿真中的应用。

全国第26届CACIS学术会议(工业4.0和工业安全篇)征文通知(第一轮)

CACIS长期致力于计算机科学与技术的研究与应用推广工作,CACIS学术会议已成为全国信息学科相关专业互相渗透和交流的重要平台。全国第26届CACIS学术会议(CACIS-2015)将于2015年8月14-16日在兰州大学举行。本届CACIS会议以"工业4.0和工业安全"为主题,聚集国内知名专家学者,探讨网络技术、分布式控制技术、机器人技术、图形图像技术、仿真技术等在工业生产与安全中的应用与研究。

全国第26届CACIS学术会议(工业4.0和工业安全篇)征文通知(第一轮)

CACIS长期致力于计算机科学与技术的研究与应用推广工作,CACIS学术会议已成为全国信息学科相关专业互相渗透和交流的重要平台。全国第26届CACIS学术会议(CACIS·2015)将于2015年8月14-16日在兰州大学举行。本届CACIS会议以"工业4.0和工业安全"为主题,聚集国内知名专家学者,探讨网络技术、分布式控制技术。

全国第26届CACIS学术会议(工业4.0和工业安全篇)征文通知(第一轮)

CACIS长期致力于计算机科学与技术的研究与应用推广工作,CACIS学术会议已成为全国信息学科相关专业互相渗透和交流的重要平台。全国第26届CACIS学术会议(CACIS.2015)将于2015年8月14-16日在兰州大学举行。本届CACIS会议以"工业4.0和工业安全"为主题,聚集国内知名专家学者,探讨网络技术、分布式控制技术、机器人技术、图形图像技术、仿真技术等在工业生产与安全中的应用与研究。会议录用论文将根据其研究领域分别推荐至《仪器仪表学报》、《计算机辅助设计与图形学学报》、《中国图象图形学报》。

全国第28届CACIS学术会议(军民融合应急技术篇)征文通知(第一轮)

CACIS长期致力于计算机科学与技术的研究与应用推广工作,CACIS学术会议已成为全国信息学科相关专业互相渗透和交流的重要平台。全国第28届CACIS学术会议（CACIS·2017）将于2017年8月11-13日在延边大学举行。本届CACIS会议以“军民融合应急技术篇”为主题,聚集国内知名专家学者,探讨建模仿真技术、机器视觉技术、图形图像技术、网络技术、分布式控制技术、VR＆AR等在军民融合应急技术中的应用与研究。