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Clinical Analysis of 45 Cases of Caesarean Scar Pregnancy 被引量:4
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作者 Hong SHI Ai-hua FANG Qin-fang CHEN 《Journal of Reproduction and Contraception》 CAS 2008年第2期101-106,共6页
Objective To summarize the clinical characteristics of caesarean scar pregnancy and to investigate its treatment.Methods Clinical case records of 45 cases of caesarean scar pregnancy from June 2003 to September 2007 w... Objective To summarize the clinical characteristics of caesarean scar pregnancy and to investigate its treatment.Methods Clinical case records of 45 cases of caesarean scar pregnancy from June 2003 to September 2007 were reviewed. The characteristics and management of cases were analyzed.Results The women's average age was 32.8 ± 5.1 years. All cases had amenorrhoea, and 27 cases had vaginal bleeding from spotting to morderate. Seven cases were misdiagnosed as normal early intrauterine pregnancy or inevitable miscarriage before dilation and curettage(D & C). In case of massive bleeding, caesarean scar pregnancy was diagnosed after D & C. Bleeding was controlled and uterus was conserved in 6 cases, and 1 case underwent hysterectomy because of uncontrollable bleeding. The remaining 38 cases had ultrasound scan, which indicated scar pregnancy before primary treatment, Eight cases were primarily treated with dilation and curettage, in which only 2 cases had slight bleeding in the operation and no further treatment, Nineteen cases were primarily treated with dilation and curettage after uterine artery embolization, in which 17 cases needed no further treatment and had no complications. The success rate was 89.4% (17/19). Eleven cases were primarily treated with trichosanthin 1.2 mg intramuscular. No one encountered massive bleeding, but 7 cases of these 11 cases needed extra treatment.Conclusion Caesarean scar pregnancy must be cautious of especially in cases of inevitable miscarriage. Dilation and curettage followed uterine artery embolization can be used as the primary treatment for caesarean scar pregnancy. 展开更多
关键词 caesarean scar pregnancy uterine artery embolization TRICHOSANTHIN
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Caesarean Scar Ectopic Pregnancies—Case Series from a District General Hospital
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作者 Folasade Akhanoba Alero Awala Tony Boret 《Open Journal of Obstetrics and Gynecology》 2017年第5期608-615,共8页
Caesarean Scar Ectopic Pregnancy (CSEP) is a rare, but potentially catastrophic complication of a previous Caesarean Section (CS) birth. This is a review of 5 cases of CSEP managed in our Early Pregnancy Unit at Watfo... Caesarean Scar Ectopic Pregnancy (CSEP) is a rare, but potentially catastrophic complication of a previous Caesarean Section (CS) birth. This is a review of 5 cases of CSEP managed in our Early Pregnancy Unit at Watford General Hospital within a 10-month period. Two patients had only one previous CS, whilst 2 had two and the last had 3 previous CS. All our patients presented within the first trimester of pregnancy (range 6 to 11 weeks’ gestation) with light vaginal bleeding;4 of them had associated mild to moderate abdominal pain. All were diagnosed using transvaginal ultrasound scan. Three of our patients were managed surgically by Suction Evacuation under Ultrasound guidance and insertion of a Foley’s catheter prophylactically for tamponade in order to reduce blood loss both intra- and post-operatively. One of our patients had a heterotopic pregnancy with a viable intrauterine pregnancy and a live CSEP. She declined any intervention so she was managed conservatively with weekly Consultant appointments and scans. There was a subsequent demise of the CSEP and she continued with a singleton pregnancy. None of our patients were managed medically. There is no absolute consensus on diagnostic criteria and there is no standard management protocol so each woman should be given all the available information and the opportunity to decide on the management of her pregnancy. The risk of a CSEP in a subsequent pregnancy should be part of the consent process for CS. 展开更多
关键词 caesarean scar ECTOPIC PREGNANCY
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Ultrasound Evaluation of Caesarean Scar of Prelabour and Labour Caesarean Sections: A Cross Sectional Analytical Study
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作者 Nisansala Perera Thiran Dias 《Open Journal of Obstetrics and Gynecology》 2023年第7期1287-1306,共20页
Caesarean section is dramatically increased throughout the world in recent years. Rupture of the uterus is a devastating complication in trial of labour following previous Caesarean section. Evidence suggests that the... Caesarean section is dramatically increased throughout the world in recent years. Rupture of the uterus is a devastating complication in trial of labour following previous Caesarean section. Evidence suggests that the size of the uterine scar and the residual myometrial thickness (RMT) are associated directly with the risk of uterine rupture and risk of dehiscence in subsequent deliveries. Impact of the prelabour and labour Cesarean section on the RMT has not been studied in detail. Objectives: To compare RMT, Caesarean scar defects and to evaluate the elasticity of the Caesarean scar between women who underwent prelabour and labour Caesarean sections. Methods: This was a Cross sectional analytical study. Women who underwent Caesarean section in their first pregnancy were recruited. Sample was stratified to prelabour and labour Caesarean section groups. Transvaginal ultrasound scan was performed six months following the Caesarean section. Dimensions of the uterus, uterine scar defect, RMT and elastosonography of the uterine scar were assessed. Results: A total of 240 postpartum women were analyzed. Uterine niche was detectable in 194 subjects. Prelabour CS group had demonstrated 91.7% (n = 110) scar defects (uterine niche) out of 120 cases and the rate among labour CS group was 70% (n = 84). There was a significant difference in the presence of uterine niche among 2 groups as Prelabour group was found to have more scar defects (p mm (SD 1.2) and 4.99 mm (SD 1.3) respectively and there was no significant difference (t = 0.38, p = 0.71). There was no significant difference between the dimensions of the uterine CS defects of the studied groups. Prelabour CS group had significantly higher Target strain [0.28 vs. 0.24 (t = 2.12, p = 0.04)] and significantly less strain ratio [1.45 vs. 1.55 (t -2.42, p = 0.04)] than labour CS group indicating a better scar in prelabour group. Conclusion: There was no significant difference in RMT and uterine scar defects between prelabour and labour Caesarean section groups. But prelabour Caesarean section scars were less stiff than labour Caesarean section scars. Further studies are warranted to elaborate on the association. 展开更多
关键词 caesarean Section scar Residual Myometrial Thickness Labour
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The Outcome of 40 Patients Becoming Pregnancy after Conservative Treatment of Cesarean Scar Pregnancy 被引量:2
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作者 Nguyen Hong Hoa Nguyen Thi Thanh Thao +1 位作者 Hoang Thi Diem Tuyet Van Phung Thong 《Case Reports in Clinical Medicine》 2020年第12期376-384,共9页
<strong>Background: </strong>The rate of uterus is successfully conserved following the treatment of scar pregnancy which is high so pregnancy outcome following caesarean scar ectopics is getting more and ... <strong>Background: </strong>The rate of uterus is successfully conserved following the treatment of scar pregnancy which is high so pregnancy outcome following caesarean scar ectopics is getting more and more attention. <strong>Objectives: </strong>To assess pregnancy course and outcome after conservative treatment of cesarean scar pregnancy. <strong>Methods:</strong> A retrospective case series of 40 patients become pregnancy after conservative treatment of cesarean scar pregnancy by Foley or Methotrexate and aspiration. Patients in present study were treated at Hung Vuong and Tu Du Hospital between 2015 and 2017. A telephone follow-up was conducted after cesarean scar pregnancy (CSP) treatment. The outcomes of these subsequent pregnancies and mode of delivery were all recorded. <strong>Results:</strong> In 40 pregnancies, there are 22 cases of intrauterine pregnancy with childbirth (55%);all babies were born healthy, with no complications recorded in pregnancy. 12 Women had recurrent scar ectopic (30%). There were 2 abortion cases, 2 cases of ectopic pregnancy, and 2 cases of early miscarriage. <strong>Conclusions:</strong> Our study shows that reproductive outcomes following treatment of caesarean scar ectopic pregnancies are favourable. The risk of recurrent caesarean scar ectopic pregnancy is a concern. 展开更多
关键词 caesarean scar Pregnancy Reproductive Outcomes
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Medical Management of Cesarean Scar Pregnancy at Latifa Hospital Dubai Health Authority, Dubai, UAE 被引量:6
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作者 A. Ammar F. Nasrallah +4 位作者 H. Adan J. Ali M. Mussa A. B. E. Fazari N. Alsawalhee 《Open Journal of Obstetrics and Gynecology》 2020年第4期526-537,共12页
Introduction: Cesarean scar pregnancy (CSP) is defined as implantation of gestational sac at the site of cesarean scar. It’s a serious diagnosis that has become more prevalent in recent years and related to the incre... Introduction: Cesarean scar pregnancy (CSP) is defined as implantation of gestational sac at the site of cesarean scar. It’s a serious diagnosis that has become more prevalent in recent years and related to the increasing rate of cesarean sections reported worldwide. Identifying these cases and treating them is challenging, with no agreed upon universal protocol for successful treatment. We aim to evaluate the success rate and outcome of medical management for Cesarean scar pregnancy. Methods: It was a retrospective descriptive study of all cesarean scar pregnancies managed at fetal medicine unit at Latifa Hospital in Dubai, UAE the main obstetrics & Gynecology tertiary hospital in Dubai Emirate, UAE from 2015 to 2017. Certainly, a set of diagnostic criteria were implemented to confirm the diagnosis of CSP. The cases were then offered our proposed management which is systemic methotrexate injections ± KCL. Follow up made by serial βhcg and ultrasound scan. The data were collected used specified data collection sheet for this purpose then analyzed and presented using statistical package for social sciences (SPSS) version 26. Results: 33 cases of cesarean scar pregnancies are confirmed and medically managed during the study period. The study subjects composed of a group of patients who had a viable CSP and received local KCL injection + systemic methotrexate, a second group who had non-viable CSP and received systemic methotrexate 20 cases were viable pregnancies who received combined local potassium chloride plus systemic methotrexate, and 13 were non-viable received systemic methotrexate only. The mean gestational age at diagnosis was 8 weeks (SD ± 1.8). On average our cases had a history of 3 previous cesarean sections (range 1 - 6). Overall, the success rate calculated from our study population for medical management of CSP was 77.8%;this varied between viable CSP which had a success rate of 66.7% and non-viable CSP which had a success rate of 100%. The average period of outpatient follow-up for the patients to achieve complete resolution was 14 weeks (SD ± 7.5). Conclusions: Medical management of CSP in the form of systemic methotrexate ± local KCL injections proves to have acceptability and a good success rate especially for non-viable CSP, low complications rate and with the benefit of preserving future fertility. 展开更多
关键词 caesarean scar Pregnancy METHOTREXATE Potassium Chloride Maternal MORBIDITY
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Predictive Factors of Complications of Vaginal Delivery on Scarred Uterus at the YaoundéGynaeco-Obstetric and Paediatric Hospital 被引量:1
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作者 E. Ngo Um Meka P. Foumane +3 位作者 F. Essiben E. R. Ngwesse J. Dohbit Sama E. T. Mboudou 《Open Journal of Obstetrics and Gynecology》 2016年第13期851-860,共10页
Objective: This study was aimed at identifying predictive factors of complications during vaginal delivery on scarred uterus. Methodology: During 9 months, from October 1st, 2015 to June 30th, 2016, a case control stu... Objective: This study was aimed at identifying predictive factors of complications during vaginal delivery on scarred uterus. Methodology: During 9 months, from October 1st, 2015 to June 30th, 2016, a case control study was carried out at the Yaoundé Gynaeco-Obstetric and Pediatric Hospital. Eighty nine women each with a single scarred uterus who presented with complications during delivery (cases) were compared to eighty nine others who had a successfully trial of scar (control) during the study period. Data were analyzed using the CSPro version 6.0 and SPSS version 20.0 softwares with statistical significance set at P Results: We recruited 2 groups of 89 women, aged 17 to 40 years, with an average age of 29.05 years. The majority of women with complications were married (50.6%) and unemployed (42.8%). Following univariate analysis, predictive factors of complications were: prematurity (OR = 7.4), post-term (OR = 13.7), no history of vaginal delivery on scarred uterus (OR = 4.3), inter-pregnancy spacing period greater than 60 months (five years) (OR = 2.9), History of caesarian delivery indicated for cephalo-pelvic disproportion (OR = 6.6), less than four ante-natal consultations (OR = 3.6), antenatal consultations done in a Health Centre (OR = 2.7), ante-natal follow up conducted by a nurse (OR = 2.4;IC = [1.2 - 4.7]), referral from a different health unit (OR = 4.4, IC = 2.0 - 9.4), a Bishop score less than 7 on admission (OR = 12.4, IC = 5.6 - 27.4), a meconium stained amniotic fluid (OR = 9.9;CI = [3.6 - 26.8]). After logistic regression, the retained factors associated with complications were post-term (aOR = 34.5), absence of vaginal birth after caesarian delivery, (aOR = 11.7), previous caesarean section indicated for cephalo-pelvic disproportion (aOR = 6.1), a bishop score less than 7 (aOR = 12.0), meconium stained amniotic fluid (aOR = 13.6). Conclusion: Predictive factors of complications can help anticipate negative obstetric outcomes. 展开更多
关键词 caesarean scarred Uterus Obstetrical Complications Predictive Factors
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子宫肌层3层缝合对剖宫产术后憩室大小的影响及子宫切口憩室形成的相关因素分析 被引量:1
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作者 陈猛 陈克功 +1 位作者 李欢欢 杜媛媛 《实用妇产科杂志》 CAS CSCD 北大核心 2024年第5期398-404,共7页
目的:探讨子宫肌层3层缝合对剖宫产术后憩室大小的影响及子宫切口憩室(CSD)形成的相关因素。方法:回顾性分析2022年4~11月于华东师范大学附属芜湖医院行剖宫产术的240例产妇的临床资料,根据子宫肌层缝合方式的不同分为3层缝合组(124例)... 目的:探讨子宫肌层3层缝合对剖宫产术后憩室大小的影响及子宫切口憩室(CSD)形成的相关因素。方法:回顾性分析2022年4~11月于华东师范大学附属芜湖医院行剖宫产术的240例产妇的临床资料,根据子宫肌层缝合方式的不同分为3层缝合组(124例)和双层缝合组(116例);另根据术后是否形成CSD将产妇分为CSD组(23例)和非CSD组(217例)。对比3层缝合组与双层缝合组产妇的临床特点,采用多因素Logistic回归分析CSD形成的独立影响因素并构建人工神经网络模型;采用受试者工作特征(ROC)曲线、校准曲线和临床决策曲线进行模型验证。结果:①3层缝合组产妇的子宫肌层瘢痕厚度显著高于双层缝合组(7.06±2.09 mm vs.5.68±1.97 mm);而CSD形成情况(4.03%vs.15.52%)和憩室大小(0.36±0.09 ml vs.0.47±0.12 ml)则显著低于双层缝合组,差异均有统计学意义(P<0.05);②多因素分析示,子宫后屈、剖宫产次数≥2次、胎膜早破、围产期感染、剖宫产时机(择期)是影响CSD形成的独立危险因素(OR>1,P<0.05),而子宫肌层3层缝合是保护性因素(OR<1,P<0.05);③人工神经网络预测模型显示剖宫产次数、胎膜早破以及是否进行3层缝合所占权重均较高,经ROC曲线、校准曲线和临床决策曲线验证表明该模型预测能力良好。结论:CSD的形成与子宫后屈、剖宫产次数、胎膜早破、围产期感染、剖宫产时机等指标有关,临床应重点关注,此外,子宫肌层3层缝合可降低CSD的形成概率,在临床上值得推广应用。 展开更多
关键词 子宫肌层 剖宫产 子宫切口憩室 3层缝合 双层缝合
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子宫动脉暂时阻断联合妊娠病灶去除术治疗Ⅱ型及Ⅲ型剖宫产瘢痕妊娠的效果和对卵巢功能的影响
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作者 李竹冰 冯梅 沈鹏 《临床和实验医学杂志》 2024年第13期1423-1427,共5页
目的评估子宫动脉暂时阻断联合妊娠病灶去除术在治疗Ⅱ型及Ⅲ型剖宫产瘢痕妊娠中的效果,以及该治疗方案对卵巢功能的潜在影响。方法前瞻性选取2020年2月至2023年2月简阳市人民医院收治的Ⅱ型及Ⅲ型剖宫产瘢痕妊娠患者103例,按照随机数... 目的评估子宫动脉暂时阻断联合妊娠病灶去除术在治疗Ⅱ型及Ⅲ型剖宫产瘢痕妊娠中的效果,以及该治疗方案对卵巢功能的潜在影响。方法前瞻性选取2020年2月至2023年2月简阳市人民医院收治的Ⅱ型及Ⅲ型剖宫产瘢痕妊娠患者103例,按照随机数字表法将患者分为对照组(n=51)和研究组(n=52)。对照组患者行腹腔镜下妊娠病灶去除术治疗,研究组患者行腹腔镜下子宫动脉暂时阻断联合妊娠病灶去除术治疗。比较两组患者的手术指标(手术时间、术中出血量、住院时间、胚物残留和中转开腹情况)、临床疗效、术后卵巢功能(卵泡刺激素、雌二醇、抗苗勒管激素以及窦卵泡数)和超声检查参数(内膜厚度、搏动指数、阻力指数)情况、术后患者恢复情况(月经恢复正常时间、绒毛膜促性腺激素-β恢复正常时间)及术后并发症发生情况。结果研究组手术时间为(97.15±12.02)min,长于对照组[(90.26±11.45)min],术中出血量和住院时间分别为(90.46±12.45)mL、(7.11±0.98)d,均短于对照组[(118.26±9.46)mL、(8.45±2.16)d],中转开腹率为0,低于对照组(3.85%),差异均有统计学意义(P<0.05);两组患者的胚物残留情况比较,差异无统计学意义(P>0.05)。两组患者的治疗有效率比较,差异无统计学意义(P>0.05)。治疗后3个月,两组的卵泡刺激素、雌二醇、抗苗勒管激素以及窦卵泡数水平等卵巢功能指标比较,差异均无统计学意义(P>0.05)。治疗后3个月,两组的内膜厚度、搏动指数、阻力指数等指标比较,差异均无统计学意义(P>0.05)。两组在月经恢复正常时间、绒毛膜促性腺激素-β恢复正常时间及总并发症发生率方面比较,差异均无统计学意义(P>0.05)。结论与单纯妊娠病灶去除术比较,采用子宫动脉暂时阻断联合妊娠病灶去除术治疗Ⅱ型及Ⅲ型剖宫产瘢痕妊娠手术时间有所延长,但术中出血量及中转开腹率显著降低,对患者的卵巢功能影响较小,术后恢复情况及并发症发生情况与单纯妊娠病灶去除术比较具有相同水平。 展开更多
关键词 子宫内膜 子宫动脉暂时阻断 妊娠病灶去除术 剖宫产瘢痕妊娠 卵巢功能
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阴式病灶切除联合子宫壁修补术治疗剖宫产瘢痕部位妊娠的效果
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作者 张鑫 《中外医学研究》 2024年第17期105-109,共5页
目的:探究阴式病灶切除联合子宫壁修补术治疗剖宫产瘢痕部位妊娠(CSP)的效果。方法:选择2019年1月—2022年1月在新泰市人民医院治疗的86例CSP患者作为研究对象,应用随机数表法分为对照组(子宫栓塞+清宫手术)及观察组(阴式病灶切除联合... 目的:探究阴式病灶切除联合子宫壁修补术治疗剖宫产瘢痕部位妊娠(CSP)的效果。方法:选择2019年1月—2022年1月在新泰市人民医院治疗的86例CSP患者作为研究对象,应用随机数表法分为对照组(子宫栓塞+清宫手术)及观察组(阴式病灶切除联合子宫壁修补术),各43例。比较两组临床指标[手术时间、术后阴道出血时间、术后β-人绒毛膜促性腺激素(β-hCG)恢复时间、住院时间]、卵巢储备功能指标[卵泡雌激素(FSH)、黄体生成素(LH)、雌二醇(E_(2))、β-hCG]、应激指标[促肾上腺皮质激素(ACTH)、醛固酮(ALD)、皮质醇(Cor)]、子宫血流动力学指标[舒张末期血流速度(EDV)、阻力指数(RI)、收缩期峰值血流速度(PSV)、搏动指数(PI)、]及并发症发生率。结果:观察组手术时间长于对照组,术后阴道出血时间、术后β-hCG恢复时间、住院时间短于对照组,差异有统计学意义(P<0.05)。术前,两组卵巢储备功能指标、应激指标、子宫血流动力学指标比较,差异无统计学意义(P>0.05)。术后7 d,两组FSH、LH高于术前,E_(2)、β-hCG低于术前,但观察组FSH、LH、β-hCG低于对照组,E_(2)高于对照组,差异有统计学意义(P<0.05)。术后7 d,两组ACTH、ALD、Cor高于术前,但观察组低于对照组,差异有统计学意义(P<0.05)。术后3 d,两组EDV、RI、PSV、PI均低于术前,且观察组低于对照组,差异有统计学意义(P<0.05)。观察组并发症总发生率低于对照组,差异有统计学意义(P<0.05)。结论:对CSP患者采用阴式病灶切除联合子宫壁修补术治疗,效果显著,手术应激反应较轻,对卵巢储备功能影响较小,可调节子宫血流动力学,降低并发症发生率。 展开更多
关键词 阴式病灶切除术 子宫壁修补术 剖宫产 子宫瘢痕妊娠
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高强度聚焦超声治疗剖宫产瘢痕妊娠的临床价值
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作者 吴海燕 刘永珠 +2 位作者 朱伟艳 张欣宁 彭奕琼 《实用妇科内分泌电子杂志》 2024年第16期1-3,8,共4页
目的分析高强度聚焦超声治疗剖宫产瘢痕妊娠的临床价值。方法选取40例剖宫产瘢痕妊娠患者,根据随机数字表法分为研究组和对照组,各20例。对照组采取子宫动脉栓塞术治疗,研究组采取高强度聚焦超声治疗。对比两组临床指标、β-人绒毛膜促... 目的分析高强度聚焦超声治疗剖宫产瘢痕妊娠的临床价值。方法选取40例剖宫产瘢痕妊娠患者,根据随机数字表法分为研究组和对照组,各20例。对照组采取子宫动脉栓塞术治疗,研究组采取高强度聚焦超声治疗。对比两组临床指标、β-人绒毛膜促性腺激素(β-HCG)转阴情况、并发症和术后疼痛评分及治疗成功率。结果两组的术中出血量、β-HCG降至正常时间、平均住院费用、住院时间、并发症发生率、治疗成功率、2周、4周的β-HCG转阴率及术后36h疼痛评分对比,差异无统计学意义(P>0.05);研究组术后12h、24h疼痛评分明显低于对照组(P<0.05)。结论高强度聚焦超声治疗剖宫产瘢痕妊娠患者,具有较高的治疗价值,安全性较好,值得临床应用。 展开更多
关键词 高强度聚焦超声 剖宫产瘢痕妊娠 子宫动脉栓塞术 并发症
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高强度聚焦超声技术在妇产科疾病中的应用进展
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作者 李慧敏 胡雅莉 +2 位作者 张森淮 马晓梅 许飞雪(审校) 《国际妇产科学杂志》 CAS 2024年第5期486-491,共6页
高强度聚焦超声(high intensity focused ultrasound,HIFU)技术是一种无创的热组织消融方法,可以通过磁共振引导高强度聚焦超声(magnetic resonance guided high intensity focused ultrasound,MRgHIFU)或超声引导高强度聚焦超声(ultras... 高强度聚焦超声(high intensity focused ultrasound,HIFU)技术是一种无创的热组织消融方法,可以通过磁共振引导高强度聚焦超声(magnetic resonance guided high intensity focused ultrasound,MRgHIFU)或超声引导高强度聚焦超声(ultrasound guided high intensity focused ultrasound,USgHIFU)实现在线图像引导和治疗控制,HIFU具有非侵入性、非电离和治疗后并发症少的优点。作为一种非手术治疗方法,在过去的10年里,HIFU技术越来越多地被应用于妇产科疾病的治疗中。HIFU通过精准聚焦超声波能量实现组织消融,对于子宫肌瘤、宫颈病变、子宫腺肌病、外阴非肿瘤性上皮疾病、剖宫产瘢痕妊娠、腹壁子宫内膜异位症、子宫动静脉瘘、双胎反向动脉灌注序列征等妇产科疾病具有良好的疗效,其优点体现在减少并发症、适合有手术禁忌证患者以及缩短恢复时间,并且对未育女性也具有重要意义。尽管HIFU在妇产科疾病治疗中展现出积极前景,但仍需进一步研究以评估其长期效果和安全性。未来,HIFU有望成为妇科疾病治疗的新选择,造福更多患者。 展开更多
关键词 体外冲击波疗法 平滑肌瘤 子宫腺肌病 宫颈上皮内瘤样病变 乳头状瘤病毒科 子宫内膜异位症 外阴非肿瘤性上皮疾病 剖宫产瘢痕妊娠 子宫动静脉瘘 双胎反向动脉灌注序列征
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卡孕栓联合缩宫素预防瘢痕子宫剖宫产产后出血的效果及对凝血指标的影响 被引量:2
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作者 梁静 谢佩真 《实用临床医学(江西)》 CAS 2024年第1期43-45,69,共4页
目的探讨卡孕栓联合缩宫素在预防瘢痕子宫剖宫产产后出血中的应用效果及其对凝血指标的影响。方法将94例行剖宫产手术的瘢痕子宫产妇随机分为观察组与对照组,每组47例。对照组在剖宫产产后采用缩宫素进行止血,观察组采用卡孕栓联合缩宫... 目的探讨卡孕栓联合缩宫素在预防瘢痕子宫剖宫产产后出血中的应用效果及其对凝血指标的影响。方法将94例行剖宫产手术的瘢痕子宫产妇随机分为观察组与对照组,每组47例。对照组在剖宫产产后采用缩宫素进行止血,观察组采用卡孕栓联合缩宫素进行止血。比较2组临床效果、产后出血量、凝血指标以及不良反应。结果与对照组相比,观察组总有效率显著升高,产后2、24 h出血量显著减少,活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)显著缩短,D-二聚体(D-D)、纤维蛋白原(FIB)水平显著升高,差异均有统计学意义(P<0.05);2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论卡孕栓联合缩宫素预防瘢痕子宫剖宫产产后出血效果显著,利于减少产妇产后出血量,改善产妇凝血功能,且安全性较高。 展开更多
关键词 瘢痕子宫 剖宫产 产后出血 卡孕栓 缩宫素 凝血指标
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宫腹腔镜联合内外兼修治疗剖宫产瘢痕部位妊娠的疗效和安全性分析
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作者 李秋兰 黄庭婷 +2 位作者 马聆桦 梁双燕 杨梅 《实用妇科内分泌电子杂志》 2024年第16期9-11,共3页
目的分析宫腹腔镜联合内外兼修治疗剖宫产瘢痕部位妊娠的效果。方法选取44例剖宫产瘢痕部位妊娠患者,根据随机数字表法分为观察组(24例)与对照组(20例)。观察组采取宫腹腔镜联合内外兼修治疗,对照组采取经阴道剖宫产瘢痕部位妊娠病灶清... 目的分析宫腹腔镜联合内外兼修治疗剖宫产瘢痕部位妊娠的效果。方法选取44例剖宫产瘢痕部位妊娠患者,根据随机数字表法分为观察组(24例)与对照组(20例)。观察组采取宫腹腔镜联合内外兼修治疗,对照组采取经阴道剖宫产瘢痕部位妊娠病灶清除术。比较两组临床疗效、术后并发症、手术指标及激素水平。结果两组成功率、术后并发症发生率比较,差异无统计学意义(P>0.05)。两组手术指标、激素水平比较,差异有统计学意义(P<0.05)。结论宫腹腔镜联合内外兼修治疗的疗效与经阴道剖宫产瘢痕部位妊娠病灶清除术相当,且具有出血量少、住院时间短优势,值得临床推广与应用。 展开更多
关键词 宫腹腔镜联合内外兼修治疗 剖宫产瘢痕部位妊娠 临床疗效 安全性
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预测剖宫产瘢痕妊娠发生风险列线图模型的建立与验证
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作者 赵旭珍 徐新燕 +1 位作者 张向楠 张晶 《医学研究杂志》 2024年第5期58-62,68,共6页
目的构建并验证剖宫产术后再妊娠女性发生剖宫产瘢痕妊娠(caesarean scar pregnancy,CSP)的风险预测模型。方法收集2018~2022年于乌鲁木齐市妇幼保健院剖宫产术后再妊娠女性663例,按7∶3随机划分为训练集(n=460)和测试集(n=203),将训练... 目的构建并验证剖宫产术后再妊娠女性发生剖宫产瘢痕妊娠(caesarean scar pregnancy,CSP)的风险预测模型。方法收集2018~2022年于乌鲁木齐市妇幼保健院剖宫产术后再妊娠女性663例,按7∶3随机划分为训练集(n=460)和测试集(n=203),将训练集病例分为CSP组(n=239)和非CSP组(n=221)。采用单因素以及多因素Logistic回归分析评价CSP发生的危险因素。基于以上结果构建列线图模型,分别在测试集和训练集中进行验证并评价。通过受试者工作特征(receiver operating characteristic,ROC)曲线下面积(area under the curve,AUC)、Hosmer-Lemeshow检验等评价模型的预测效能,使用临床决策曲线分析(decision curve analysis,DCA)评估模型的临床应用价值。结果多因素Logistic回归分析结果显示,剖宫产次数>1次、子宫后位、流产次数>1次、剖宫产瘢痕憩室、本次妊娠距前次剖宫产间流产史是CSP发生的危险因素(P<0.05),剖宫产时机为产程中是CSP发生的保护因素(P<0.05)。基于以上结果构建列线图预测模型,模型在训练集中AUC为0.813(95%CI:0.773~0.852);在测试集中AUC为0.817(95%CI:0.755~0.878);训练集和测试集Hosmer-Lemeshow拟合优度检验该模型拟合度良好(χ^(2)=7.647,P=0.469;χ^(2)=6.162,P=0.629)。校准曲线显示,该模型在预测剖宫产术后再妊娠发生CSP具有较好的一致性,DCA曲线显示,模型在训练集和测试集中均具有较高的临床效能。结论以上研究构建的预测模型能有效预测CSP的发生,可为高风险人群早期识别和预防性治疗提供参考。 展开更多
关键词 剖宫产瘢痕妊娠 影响因素 列线图模型
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不同术式对剖宫产瘢痕部位妊娠疗效及预后的影响
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作者 曾克非 夏婷婷 +1 位作者 吴小兰 雷详华 《实用妇产科杂志》 CAS CSCD 北大核心 2024年第9期751-755,共5页
目的:探讨不同术式对剖宫产瘢痕部位妊娠(CSP)患者治疗效果及预后的影响。方法:选择2021年2月1日至2022年1月31日于井冈山大学附属医院妇产科收治的Ⅱ型或Ⅲ型CSP患者90例为研究对象,按照纳入、排除标准及入院治疗的时间顺序依次入组,... 目的:探讨不同术式对剖宫产瘢痕部位妊娠(CSP)患者治疗效果及预后的影响。方法:选择2021年2月1日至2022年1月31日于井冈山大学附属医院妇产科收治的Ⅱ型或Ⅲ型CSP患者90例为研究对象,按照纳入、排除标准及入院治疗的时间顺序依次入组,根据治疗方式依次纳入A组30例、B组30例和C组30例。A组接受腹腔镜下子宫动脉结扎术(UAL)+子宫瘢痕妊娠病灶切除术(FER)+子宫瘢痕修补术(UCR),B组接受子宫动脉栓塞术(UAE)+超声监测下宫腔镜FER,C组接受腹腔镜下FER+UCR。比较3组的术中、术后情况及随访复发性CSP(RCSP)的发生率和再妊娠率。结果:①A组、B组的术中出血量、术后宫腔引流量、术后疼痛视觉模拟(VAS)评分低于C组,而手术时间、住院费用高于C组,以上差异均有统计学意义(P<0.05);A组手术时间、住院费用低于B组(P<0.05)。②A组、B组术后阴道停止流血时间、月经恢复时间和血β-人绒毛膜促性腺激素(β-hCG)恢复时间短于C组(P<0.05)。③3组术后并发症(盆腔粘连、感染、术后大出血及下腹疼痛)的发生率差异均无统计学意义(P>0.05)。④术后平均随访时间17.60±5.61个月,A组、C组RCSP发生率低于B组(P<0.05)。A组、B组、C组再次妊娠率分别为82.14%(23/28)、77.78%(21/27)、81.48%(22/27),差异无统计学意义(P>0.05)。结论:腹腔镜下UAL+FER+UCR和UAE+超声监测下宫腔镜FER能减少术中出血量,促进术后康复,只是手术时间延长、住院费用较高;采用UCR治疗后RCSP发生率更低,临床应结合Ⅱ型、Ⅲ型CSP患者具体病情、经济条件和保留生育功能需求等进行综合评估并制定个体化的治疗方案。 展开更多
关键词 剖宫产瘢痕部位妊娠 瘢痕妊娠病灶切除术 子宫瘢痕修补术 子宫动脉结扎术 子宫动脉栓塞术
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无创皮肤吻合器联合心形缝合皮下脂肪对腹部瘢痕的影响
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作者 龚逞英 罗序清 廖凤娇 《中国医学创新》 CAS 2024年第8期60-64,共5页
目的:探讨无创皮肤吻合器联合心形缝合皮下脂肪对腹部瘢痕的影响。方法:回顾性分析2021年1月—2022年9月于新余市妇幼保健院行剖宫产手术的120例患者的病历资料,将接受无创皮肤吻合器联合心形缝合的60例患者纳入A组,将接受无创皮肤吻合... 目的:探讨无创皮肤吻合器联合心形缝合皮下脂肪对腹部瘢痕的影响。方法:回顾性分析2021年1月—2022年9月于新余市妇幼保健院行剖宫产手术的120例患者的病历资料,将接受无创皮肤吻合器联合心形缝合的60例患者纳入A组,将接受无创皮肤吻合器联合传统美容缝合的60例患者纳入B组,两组出院后均随访6个月。比较两组切口缝合时间、切口愈合时间及住院时间,术后24 h、72 h、7 d切口疼痛[视觉模拟评分法(VAS)],术后1个月切口愈合情况、切口并发症发生率,术后6个月切口瘢痕情况[温哥华瘢痕评定量表(VSS)]、缝合效果满意度。结果:两组切口缝合时间差异无统计学意义(P>0.05),A组切口愈合时间与住院时间均短于B组,差异均有统计学意义(P<0.05);两组术后24 h、72 h VAS评分差异均无统计学意义(P>0.05),A组术后7 d VAS评分低于B组,差异有统计学意义(P<0.05);术后1个月,A组伤口愈合等级优于B组,A组切口并发症总发生率低于B组,差异均有统计学意义(P<0.05);术后6个月,A组VSS评分低于B组,A组缝合效果满意度高于B组,差异均有统计学意义(P<0.05)。结论:无创皮肤吻合器联合心形缝合皮下脂肪在剖宫产患者中应用价值高,能有效促进术后患者腹部切口愈合,减少术后疼痛,降低切口并发症发生及瘢痕增生风险,并获得更高的患者满意度。 展开更多
关键词 无创皮肤吻合器 心形缝合 腹部瘢痕 剖宫产手术
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子宫动脉栓塞术后清宫术治疗剖宫产术后子宫瘢痕妊娠的临床效果研究
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作者 周刚 《中国实用医药》 2024年第18期64-66,共3页
目的探讨对剖宫产术后子宫瘢痕妊娠患者使用子宫动脉栓塞术后清宫术治疗的临床效果。方法72例剖宫产术后子宫瘢痕妊娠患者作为研究对象,随机分为对照组(36例)及观察组(36例)。对照组给予开腹病灶清除术或药物联合宫腔镜下清宫术治疗,观... 目的探讨对剖宫产术后子宫瘢痕妊娠患者使用子宫动脉栓塞术后清宫术治疗的临床效果。方法72例剖宫产术后子宫瘢痕妊娠患者作为研究对象,随机分为对照组(36例)及观察组(36例)。对照组给予开腹病灶清除术或药物联合宫腔镜下清宫术治疗,观察组使用子宫动脉栓塞术后清宫术治疗。比较两组患者手术情况及临床指标,术后不良反应发生情况。结果观察组术中出血量(50.25±13.05)ml少于对照组的(85.35±14.00)ml,手术时间(1.02±0.54)h、住院时间(4.95±2.05)d、人绒毛膜促性腺激素(β-HCG)降至正常时间(16.85±3.80)d短于对照组的(1.65±0.68)h、(7.50±2.15)d、(27.05±5.85)d,比较有统计学意义(P<0.05)。观察组患者术后出现月经不调2例、下腹痛1例,不良反应发生率为8.3%(3/36);对照组患者术后出现月经不调5例、大出血3例、下腹痛2例、低热1例,不良反应发生率为30.6%(11/36)。观察组患者术后不良反应发生率明显低于对照组,比较有统计学意义(χ^(2)=5.675,P=0.017<0.05)。结论临床中剖宫产术后子宫瘢痕妊娠患者使用子宫动脉栓塞术后清宫术治疗,能缩短患者的手术时间、住院时间,减少术中出血量,使患者的不适感减轻,且术后血清中β-HCG恢复正常水平较快,该治疗方式值得临床进一步推广应用。 展开更多
关键词 子宫动脉栓塞术 清宫术 剖宫产 子宫瘢痕妊娠
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髂内动脉临时阻断术联合宫腔镜下病灶清除术在剖宫产瘢痕妊娠患者中的应用
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作者 黄莉 范造锋 《河南医学研究》 CAS 2024年第19期3556-3559,共4页
目的探讨髂内动脉临时阻断术联合宫腔镜下病灶清除术在剖宫产瘢痕妊娠患者中的应用效果。方法采取前瞻性研究,将洛阳市妇幼保健院2020年10月至2022年10月收治的80例剖宫产瘢痕妊娠患者纳入研究,按随机数字表法分成两组,各40例。对照组... 目的探讨髂内动脉临时阻断术联合宫腔镜下病灶清除术在剖宫产瘢痕妊娠患者中的应用效果。方法采取前瞻性研究,将洛阳市妇幼保健院2020年10月至2022年10月收治的80例剖宫产瘢痕妊娠患者纳入研究,按随机数字表法分成两组,各40例。对照组接受子宫动脉栓塞术联合宫腔镜下病灶清除术治疗,观察组接受髂内动脉临时阻断术联合宫腔镜下病灶清除术治疗。观察记录两组患者的手术相关指标;于手术后12、24、48 h,通过视觉模拟评分法(VAS)评估患者疼痛程度;比较两组患者术后并发症总发生率。结果观察组患者手术时间、血人绒毛膜促性腺激素(β-HGG)恢复正常时间、住院时间均短于对照组,术中出血量少于对照组(P<0.05);两组术后12 h、24 h及48 h的VAS评分均持续降低,且观察组VAS评分低于对照组(P<0.05);观察组术后并发症总发生率低于对照组(P<0.05)。结论髂内动脉临时阻断术联合宫腔镜下病灶清除术能够减轻剖宫产瘢痕妊娠患者术后疼痛程度,降低术后并发症发生率,在剖宫产瘢痕妊娠患者的治疗中应用效果较好。 展开更多
关键词 剖宫产瘢痕妊娠 髂内动脉临时阻断术 宫腔镜 病灶清除术 子宫动脉栓塞术
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产程进展角、胎头下降距离及其变化率在剖宫产术后瘢痕子宫经阴道试产结局预测中的价值
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作者 王忆君 沈丹萍 +5 位作者 袁国芳 陈萍 石云 朱峰 裘琳 王嘉宁 《实用临床医药杂志》 CAS 2024年第20期103-107,共5页
目的探讨产程进展角(AOP)、胎头下降距离(HPD)及其变化率在剖宫产术后瘢痕子宫经阴道试产结局预测中的价值。方法选取剖宫产术后瘢痕子宫再次妊娠经阴道试产的170例孕妇为研究对象,依据试产结局将其分为成功组和失败组。分别采用超声测... 目的探讨产程进展角(AOP)、胎头下降距离(HPD)及其变化率在剖宫产术后瘢痕子宫经阴道试产结局预测中的价值。方法选取剖宫产术后瘢痕子宫再次妊娠经阴道试产的170例孕妇为研究对象,依据试产结局将其分为成功组和失败组。分别采用超声测量第一产程活跃期宫口扩张至4 cm时以及1 h时(宫口开至4 cm后1 h)AOP、HPD,并计算1 h时AOP变化率、HPD变化率。采用受试者工作特征(ROC)曲线分析AOP、HPD及其变化率对剖宫产术后瘢痕子宫再次妊娠经阴道试产结局的预测效能,采用Delong检验比较不同曲线下面积(AUC)的差异。结果170例剖宫产术后瘢痕子宫再次妊娠孕妇中,经阴道试产成功分娩为139例(成功组),试产失败转剖宫产为31例(失败组)。成功组在宫口开至4 cm时的AOP大于失败组,HPD短于失败组,差异均有统计学意义(P<0.05);成功组宫口开至4 cm、1 h时的AOP变化率、HPD变化率均大于失败组,差异有统计学意义(P<0.05)。AOP与HPD预测剖宫产术后瘢痕子宫再次妊娠经阴道试产结局的AUC分别为0.846、0.812,AOP与HPD联合预测的AUC与单独预测的AUC比较,差异无统计学意义(P>0.05)。AOP与HPD的变化率预测剖宫产术后瘢痕子宫再次妊娠经阴道试产结局的AUC分别为0.899、0.852;AOP变化率与HPD变化率联合预测的AUC大于单独预测的AUC,且大于AOP与HPD联合预测的AUC,差异均有统计学意义(P<0.05)。结论第一产程活跃期宫口扩张至4 cm时的AOP、HPD及其变化率对剖宫产术后瘢痕子宫再次妊娠经阴道试产结局具有预测价值。 展开更多
关键词 产程进展角 胎头下降距离 瘢痕子宫 阴道试产 剖宫产
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高龄二胎产妇剖宫产后子宫瘢痕愈合不良的Nomogram预测模型的构建及其应用价值
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作者 张全华 余冰洁 +1 位作者 李冉 任艳芳 《海南医学》 2024年第2期230-236,共7页
目的 构建高龄二胎产妇剖宫产后子宫瘢痕愈合不良(PHUI)的列线图(Nomogram)预测模型,并探讨其临床应用价值。方法 回顾性分析2019年1月至2021年12月新乡医学院第一附属医院收治的277例高龄二胎剖宫产产妇的临床资料,依据所有产妇的子宫... 目的 构建高龄二胎产妇剖宫产后子宫瘢痕愈合不良(PHUI)的列线图(Nomogram)预测模型,并探讨其临床应用价值。方法 回顾性分析2019年1月至2021年12月新乡医学院第一附属医院收治的277例高龄二胎剖宫产产妇的临床资料,依据所有产妇的子宫瘢痕愈合情况分为子宫瘢痕愈合良好(GHUI)组204例和PHUI组73例,经单因素分析后采用Logistic回归分析高龄二胎产妇剖宫产后PHUI的影响因素,构建Nomogram预测模型,并采用受试者工作特征曲线(ROC)及曲线下面积(AUC)进行临床应用性验证。结果 经单因素分析结果显示,年龄、孕期增重、贫血、既往剖宫产史、子宫位置、手术时机、术者年资、切口与宫颈内口距离、胎膜早破、羊水污染、术后感染是高龄二胎产妇剖宫产后PHUI的影响因素(P<0.05);经Logistic回归分析结果显示,年龄、贫血、既往剖宫产史、子宫位置、手术时机、切口与宫颈内口距离、胎膜早破、羊水污染、术后感染是高龄二胎产妇剖宫产后PHUI的独立影响因素(P<0.05);根据Logistic回归方程构建高龄二胎产妇剖宫产后PHUI的Nomograms预测模型,经检验,该模型C-index为0.921,校准度为0.873,预测高龄二胎产妇剖宫产后PHUI的AUC为0.868 (95%CI:0.822~0.916),敏感度为84.93%,特异度为70.10%;且经临床验证,该模型预测高龄二胎产妇剖宫产后PHUI的AUC为0.885 (95%CI:0.825~0.949),敏感度为85.29%,特异度为77.66%。结论 基于年龄、贫血、既往剖宫产史、子宫位置、手术时机、切口与宫颈内口距离、胎膜早破、羊水污染、术后感染等临床资料构建高龄二胎产妇剖宫产后PHUI的预测模型具有可行性,且其预测价值高,临床应用性可靠。 展开更多
关键词 高龄 二胎 产妇 剖宫产 子宫瘢痕愈合不良 临床资料 列线图预测模型 临床应用性
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