Background:The“Controlled Aliasing In Parallel Imaging Results In Higher Acceleration”(CAPIRINHA)technique greatly accelerates T1w 3D fast low angle shot(FLASH)scans while maintaining high image quality.We studied i...Background:The“Controlled Aliasing In Parallel Imaging Results In Higher Acceleration”(CAPIRINHA)technique greatly accelerates T1w 3D fast low angle shot(FLASH)scans while maintaining high image quality.We studied image quality and conspicuity of inflammatory lesions on CAIPIRINHA-accelerated imaging for pediatric small-bowel magnetic resonance imaging(MRI).Methods:Forty-four consecutive patients(mean 14±3 years,18 girls)underwent small-bowel MRI(MR enterography,MRE)at 1.5 T including diffusion-weighted imaging(DWI),contrast-enhanced CAIPIRINHA 3D-FLASH and standard 2D-FLASH imaging.Crohn’s disease(CD)was confirmed in 26 patients,18 patients served as control.Independent blinded readings were performed for grading of image quality and conspicuity of CD lesions on CAIPIRINHA FLASH and standard FLASH images in comparison to a reference standard comprising imaging and endoscopic data.Results:CAIPIRINHA FLASH yielded significantly higher image quality with good inter-observer agreement(κ=0.68)and showed better visual delineation in 40%of the assessed bowel lesions,as compared to standard FLASH.There was full agreement for identification of CD patients between CAIPIRINHA and standard FLASH.CAIPIRINHA FLASH detected two small-bowel lesions that were not seen on standard FLASH.DWI revealed additional inflammatory lesions inconspicuous on contrast-enhanced imaging.MRE showed an overall diagnostic accuracy of 93%.Conclusion:We present first evidence that CAIPIRINHA greatly accelerates T1w imaging in paediatric MRE without trade-off in image quality or lesion conspicuity and is thus preferable to standard FLASH imaging.展开更多
Controlled aliasing in parallel imaging results in higher acceleration （CAIPIRINHA） for simultaneous multislice imaging has been proposed recently, which combines multiband excitation and phase cycling techniques to...Controlled aliasing in parallel imaging results in higher acceleration （CAIPIRINHA） for simultaneous multislice imaging has been proposed recently, which combines multiband excitation and phase cycling techniques to reduce scan time and improve subsequent imaging reconstruction. In this work, the total variation （TV） regularization method is used to further improve CAIPIRINHA. The TV regularization uses an edge-preserving prior, which establishes a relationship between neighboring pixels for image reconstruction. It reduces artifacts and suppresses noise amplification simultaneously. The results are presented with a standard eight-channel head coil with an acceleration factor of 4, where the TV-regularized CAIPIRINHA generates an improved reconstruction as compared with a typical nonregularized CAIPIRINHA.展开更多
文摘Background:The“Controlled Aliasing In Parallel Imaging Results In Higher Acceleration”(CAPIRINHA)technique greatly accelerates T1w 3D fast low angle shot(FLASH)scans while maintaining high image quality.We studied image quality and conspicuity of inflammatory lesions on CAIPIRINHA-accelerated imaging for pediatric small-bowel magnetic resonance imaging(MRI).Methods:Forty-four consecutive patients(mean 14±3 years,18 girls)underwent small-bowel MRI(MR enterography,MRE)at 1.5 T including diffusion-weighted imaging(DWI),contrast-enhanced CAIPIRINHA 3D-FLASH and standard 2D-FLASH imaging.Crohn’s disease(CD)was confirmed in 26 patients,18 patients served as control.Independent blinded readings were performed for grading of image quality and conspicuity of CD lesions on CAIPIRINHA FLASH and standard FLASH images in comparison to a reference standard comprising imaging and endoscopic data.Results:CAIPIRINHA FLASH yielded significantly higher image quality with good inter-observer agreement(κ=0.68)and showed better visual delineation in 40%of the assessed bowel lesions,as compared to standard FLASH.There was full agreement for identification of CD patients between CAIPIRINHA and standard FLASH.CAIPIRINHA FLASH detected two small-bowel lesions that were not seen on standard FLASH.DWI revealed additional inflammatory lesions inconspicuous on contrast-enhanced imaging.MRE showed an overall diagnostic accuracy of 93%.Conclusion:We present first evidence that CAIPIRINHA greatly accelerates T1w imaging in paediatric MRE without trade-off in image quality or lesion conspicuity and is thus preferable to standard FLASH imaging.
基金Project supported by the National Natural Science Foundation of China(Grant No.61671026)the Natural Science Foundation of Beijing,China(Grant No.7162112)
文摘Controlled aliasing in parallel imaging results in higher acceleration （CAIPIRINHA） for simultaneous multislice imaging has been proposed recently, which combines multiband excitation and phase cycling techniques to reduce scan time and improve subsequent imaging reconstruction. In this work, the total variation （TV） regularization method is used to further improve CAIPIRINHA. The TV regularization uses an edge-preserving prior, which establishes a relationship between neighboring pixels for image reconstruction. It reduces artifacts and suppresses noise amplification simultaneously. The results are presented with a standard eight-channel head coil with an acceleration factor of 4, where the TV-regularized CAIPIRINHA generates an improved reconstruction as compared with a typical nonregularized CAIPIRINHA.
