Objective To explore effects of acupuncture on senJm tumor necrosis factor (TNF) and ,γ-inter- feron (INF-γ) contents in the operative patient of lung cancer. Methods In the first stage, electroacupuncture (EA...Objective To explore effects of acupuncture on senJm tumor necrosis factor (TNF) and ,γ-inter- feron (INF-γ) contents in the operative patient of lung cancer. Methods In the first stage, electroacupuncture (EA) stimulation was given to 25 cases of lung cancer before operation, once daily for 3 consecutive days, with continuous EA stimulation during operation; EA was given once each day from the 5^th-7^th days after operation. In the second stage, EA was added from the 8^th- 10^th days after operation in 30 cases, once daily. Serum TNF and INF-γ contents were compared before and after operation. Results Serum TNF content on the 8th day after operation in the first stage study was lower (P〈0.05) and on the 12th day after operation in the second stage study was higher (P〈0.05) in the compound anesthesia group than that in the general anesthesia group; serum INF-γ contents in the compound anesthesia group on the 8^th day after operation in the first stage and on the 12^th day after operation in the second stage were significantly higher than those in the general anesthesia group (P〈0.01, P〈0.05). Conclusion Acupuncture can regulate serum TNF and INF-γ contents in the patient of operation of lung cancer, with dual-directional regulation on immunologic function.展开更多
文摘Objective To explore effects of acupuncture on senJm tumor necrosis factor (TNF) and ,γ-inter- feron (INF-γ) contents in the operative patient of lung cancer. Methods In the first stage, electroacupuncture (EA) stimulation was given to 25 cases of lung cancer before operation, once daily for 3 consecutive days, with continuous EA stimulation during operation; EA was given once each day from the 5^th-7^th days after operation. In the second stage, EA was added from the 8^th- 10^th days after operation in 30 cases, once daily. Serum TNF and INF-γ contents were compared before and after operation. Results Serum TNF content on the 8th day after operation in the first stage study was lower (P〈0.05) and on the 12th day after operation in the second stage study was higher (P〈0.05) in the compound anesthesia group than that in the general anesthesia group; serum INF-γ contents in the compound anesthesia group on the 8^th day after operation in the first stage and on the 12^th day after operation in the second stage were significantly higher than those in the general anesthesia group (P〈0.01, P〈0.05). Conclusion Acupuncture can regulate serum TNF and INF-γ contents in the patient of operation of lung cancer, with dual-directional regulation on immunologic function.