Reasonable design and controllable synthesis of non-Pt catalysts with high methanol oxidation activity are regarded as a valid way to promote the large-scale com-mercial applications of direct methanol fuel cells(DMFC...Reasonable design and controllable synthesis of non-Pt catalysts with high methanol oxidation activity are regarded as a valid way to promote the large-scale com-mercial applications of direct methanol fuel cells(DMFCs).Herein,we develop a convenient and cost-ef-fective approach to the successful fabrication of nanosized Rh grown on single-walled carbon nanohorns(Rh/SWCNH)as anode catalysts for DMFCs.The unique architectural configuration endows the as-obtained hybrids with a series of intriguing structural merits,including large specific surface areas,abundant opened holes,optimized electronic structures,homogeneous Rh dispersion,and good electrical conductivity.As a consequence,the resulting Rh/SWCNH catalysts exhibit exceptional elec-trocatalytic properties in terms of a large electrochemically active surface area of 102.5 m^(2)·g^(-1),a high mass activity of 784.0 mA·mg^(-1),as well as reliable long-term durability towards the methanol oxidation reaction in alkaline media,thereby holding great potential as alternatives for com-mercial Pt/carbon black and Pd/carbon black catalysts.展开更多
Nitrogen-doped graphene/carbon nanohorns composite（NGLC） was prepared by one-step co-pyrolysis of graphene oxide, carbon nanohorns（CNHs）, urea, and lignosulfonate. CNHs as spacers were inserted into graphene nanos...Nitrogen-doped graphene/carbon nanohorns composite（NGLC） was prepared by one-step co-pyrolysis of graphene oxide, carbon nanohorns（CNHs）, urea, and lignosulfonate. CNHs as spacers were inserted into graphene nanosheets. The introduction of CNHs and the loosened nano-structure of NGLC make it achieve a high specific capacitance of 363 Fg^（-1） at a discharge current density of 1 A g^（-1）, and NGLC exhibits an ultrahigh stability of 93.5% capacitance retention ratio after 5000 cycles. The outstanding comprehensive electrochemical performance of NGLC could meet the need of the future acted as an efficient supercapacitor electrode material.展开更多
1 Results Single-walled carbon nanohorn (SWNH) aggregate ,composed of thousands of graphitic tubules (2 -5nmin diameter and 40 -50 nminlength) with a conical"horn-like"cap,has spherical structure with a diam...1 Results Single-walled carbon nanohorn (SWNH) aggregate ,composed of thousands of graphitic tubules (2 -5nmin diameter and 40 -50 nminlength) with a conical"horn-like"cap,has spherical structure with a diam-eter of about 100 nm(Fig.1)[1].The SWNHs contain no metal catalyst ,because they are produced bylaserablation of pure graphite targets .展开更多
Photothermal(PTT) and photodynamic(PDT) combined therapy has been hindered to clinical translation, due to the lack of available biomaterials, difficult designs of functions,and complex chemical synthetic or preparati...Photothermal(PTT) and photodynamic(PDT) combined therapy has been hindered to clinical translation, due to the lack of available biomaterials, difficult designs of functions,and complex chemical synthetic or preparation procedures. To actualize a high-efficiency combination therapy for cancer via a feasible approach, three readily available materials are simply associated together in one-pot, namely the single-walled carbon nanohorns(SWCNH), zinc phthalocyanine(ZnPc), and surfactant TPGS. The established nanodispersion is recorded as PCT. The association of SWCNH/ZnPc/TPGS was confirmed by energy dispersive spectrum, Raman spectrum and thermogravimetric analysis. Under lighting, PCT induced a temperature rising up to about 60 ℃ due to the presence of SWCNH, production a 7-folds of singlet oxygen level elevation because of ZnPc, which destroyed almost all4T1 tumor cells in vitro. The photothermal effect of PCT depended on both laser intensity and nanodispersion concentration in a linear and nonlinear manner, respectively. After a single peritumoral injection in mice and laser treatment, PCT exhibited the highest tumor temperature rise(to 65 ℃) among all test groups, completely destroyed primary tumor without obvious toxicity, and inhibited distant site tumor. Generally, this study demonstrated the high potential of PCT nanodispersion in tumor combined therapy.展开更多
Protein and peptide phosphorylation regulate numerous pathological processes,however,their characterization is challenging due to their low abundance and transient nature.Therefore,nanomaterials are being developed to...Protein and peptide phosphorylation regulate numerous pathological processes,however,their characterization is challenging due to their low abundance and transient nature.Therefore,nanomaterials are being developed to address this demanding task.In particular,carbon nanostructures are attracting interest as scaffolds for functional nanocomposites,yet only isolated studies exist on the topic,and lttle is known on the effect of nanocarbon morphology on templating nanocomposites.In this work,we compared oxidized carbon nanotubes,graphene oxide,oxidized carbon nanohorns and oxidized graphitized carbon black,as scaffolds for magnetized nanocomposites.The nanomaterials were extensively characterized with experimental and in silico techniques.Next,they were applied to phosphopeptide enrichment from cancer cell lysates for NanoHPLC-MS/MS,with selectivity as high as nearly 90%and several-thousand identification hits.Overall,new insights emerged for the understanding and the design of nanocomposites for phosphoproteomics.展开更多
基金financially supported by the National Natural Science Foundation of China (No.51802077)the Fundamental Research Funds for the Central Universities (No. B210202093)
文摘Reasonable design and controllable synthesis of non-Pt catalysts with high methanol oxidation activity are regarded as a valid way to promote the large-scale com-mercial applications of direct methanol fuel cells(DMFCs).Herein,we develop a convenient and cost-ef-fective approach to the successful fabrication of nanosized Rh grown on single-walled carbon nanohorns(Rh/SWCNH)as anode catalysts for DMFCs.The unique architectural configuration endows the as-obtained hybrids with a series of intriguing structural merits,including large specific surface areas,abundant opened holes,optimized electronic structures,homogeneous Rh dispersion,and good electrical conductivity.As a consequence,the resulting Rh/SWCNH catalysts exhibit exceptional elec-trocatalytic properties in terms of a large electrochemically active surface area of 102.5 m^(2)·g^(-1),a high mass activity of 784.0 mA·mg^(-1),as well as reliable long-term durability towards the methanol oxidation reaction in alkaline media,thereby holding great potential as alternatives for com-mercial Pt/carbon black and Pd/carbon black catalysts.
基金support from the National Natural Science Foundation of China (Grant No. 51503041)the Natural Science Foundation of Fujian Province, China (Grant No. 2016J01729)the Key Program of Youth Natural Science Foundation of Fujian Province University, China (Grant No. JZ160413)
文摘Nitrogen-doped graphene/carbon nanohorns composite（NGLC） was prepared by one-step co-pyrolysis of graphene oxide, carbon nanohorns（CNHs）, urea, and lignosulfonate. CNHs as spacers were inserted into graphene nanosheets. The introduction of CNHs and the loosened nano-structure of NGLC make it achieve a high specific capacitance of 363 Fg^（-1） at a discharge current density of 1 A g^（-1）, and NGLC exhibits an ultrahigh stability of 93.5% capacitance retention ratio after 5000 cycles. The outstanding comprehensive electrochemical performance of NGLC could meet the need of the future acted as an efficient supercapacitor electrode material.
文摘1 Results Single-walled carbon nanohorn (SWNH) aggregate ,composed of thousands of graphitic tubules (2 -5nmin diameter and 40 -50 nminlength) with a conical"horn-like"cap,has spherical structure with a diam-eter of about 100 nm(Fig.1)[1].The SWNHs contain no metal catalyst ,because they are produced bylaserablation of pure graphite targets .
基金supported by the National Natural Science Foundation of China(20803001,20973003,51121091,21133001)National Key Basic Research Special Foundation of China(2011CB808702)~~
基金supported by the National Natural Science Foundation of China (81690264)the National Basic Research Program of China (2015CB932100)the Innovation Team of the Ministry of Education (BMU20110263)。
文摘Photothermal(PTT) and photodynamic(PDT) combined therapy has been hindered to clinical translation, due to the lack of available biomaterials, difficult designs of functions,and complex chemical synthetic or preparation procedures. To actualize a high-efficiency combination therapy for cancer via a feasible approach, three readily available materials are simply associated together in one-pot, namely the single-walled carbon nanohorns(SWCNH), zinc phthalocyanine(ZnPc), and surfactant TPGS. The established nanodispersion is recorded as PCT. The association of SWCNH/ZnPc/TPGS was confirmed by energy dispersive spectrum, Raman spectrum and thermogravimetric analysis. Under lighting, PCT induced a temperature rising up to about 60 ℃ due to the presence of SWCNH, production a 7-folds of singlet oxygen level elevation because of ZnPc, which destroyed almost all4T1 tumor cells in vitro. The photothermal effect of PCT depended on both laser intensity and nanodispersion concentration in a linear and nonlinear manner, respectively. After a single peritumoral injection in mice and laser treatment, PCT exhibited the highest tumor temperature rise(to 65 ℃) among all test groups, completely destroyed primary tumor without obvious toxicity, and inhibited distant site tumor. Generally, this study demonstrated the high potential of PCT nanodispersion in tumor combined therapy.
基金Shanghai Municipal Education Commission(J51504,13YZ118)National Natural Science Foundation of China(21306113,51074107)+1 种基金Shanghai Institute of Technology(YJ2013-1)Pujiang Talent Project(13PJ1407400)
基金This work was supported by PRIN 2015,project number 2015TWP83ZThe authors would like to acknowledge networking support by the COST Action MultiComp CAI5107,as well as financial support from the Slovenian Research Agency(ARRS)for research core funding No.(P2-0089)and projects No.(J1-7302 and J3-7494).
文摘Protein and peptide phosphorylation regulate numerous pathological processes,however,their characterization is challenging due to their low abundance and transient nature.Therefore,nanomaterials are being developed to address this demanding task.In particular,carbon nanostructures are attracting interest as scaffolds for functional nanocomposites,yet only isolated studies exist on the topic,and lttle is known on the effect of nanocarbon morphology on templating nanocomposites.In this work,we compared oxidized carbon nanotubes,graphene oxide,oxidized carbon nanohorns and oxidized graphitized carbon black,as scaffolds for magnetized nanocomposites.The nanomaterials were extensively characterized with experimental and in silico techniques.Next,they were applied to phosphopeptide enrichment from cancer cell lysates for NanoHPLC-MS/MS,with selectivity as high as nearly 90%and several-thousand identification hits.Overall,new insights emerged for the understanding and the design of nanocomposites for phosphoproteomics.
