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肺炎支原体CARDS毒素依赖KELED序列调控炎性反应
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作者 许钰铃 杨婷钰 +1 位作者 宋楠 李洁琼 《标记免疫分析与临床》 CAS 2024年第9期1698-1703,共6页
目的细胞内逆向运输系统是微生物毒素蛋白导致细胞毒性的关键。KELED序列是肺炎支原体CARDS毒素逆向转运至内质网,而后发挥细胞毒性作用的关键氨基酸基序。在小鼠模型中,体外重组的CARDS蛋白可以重现肺炎支原体肺炎患者的特征性症状。然... 目的细胞内逆向运输系统是微生物毒素蛋白导致细胞毒性的关键。KELED序列是肺炎支原体CARDS毒素逆向转运至内质网,而后发挥细胞毒性作用的关键氨基酸基序。在小鼠模型中,体外重组的CARDS蛋白可以重现肺炎支原体肺炎患者的特征性症状。然而,CARDS是否依赖于KELED序列调控肺组织炎性反应仍不清楚。方法在大肠杆菌中表达并纯化CARDS及其KELED序列突变蛋白;随后在细胞水平验证其致空泡化活性;最后,在小鼠模型中评价KELED序列突变的CARDS蛋白是否影响炎性因子的表达以及是否造成肺组织病理学损伤。结果KELED序列氨基酸发生突变,减弱CARDS蛋白致细胞空泡化效应,下调肺组织炎性因子mRNA表达,减轻肺组织的病理学损伤。结论KELED序列对CARDS蛋白致细胞空泡化及炎性损伤活性的维持至关重要。 展开更多
关键词 肺炎支原体 cards毒素 KELED序列 炎性反应
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肺炎支原体CARDS毒素蛋白多表位拼接抗原的表达及鉴定 被引量:3
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作者 刘宝山 赵芝娜 +1 位作者 赵雨杰 王桂珍 《中国人兽共患病学报》 CAS CSCD 北大核心 2017年第7期588-591,共4页
目的探讨肺炎支原体CARDS毒素蛋白多表位拼接抗原的免疫反应活性。方法对CARDS毒素蛋白的抗原表位进行分析,选取10个重要的表位进行拼接,反向翻译后合成并克隆,插入pET28a表达载体构建pET-CARDS表达质粒并转入受体菌。经IPTG诱导表达的... 目的探讨肺炎支原体CARDS毒素蛋白多表位拼接抗原的免疫反应活性。方法对CARDS毒素蛋白的抗原表位进行分析,选取10个重要的表位进行拼接,反向翻译后合成并克隆,插入pET28a表达载体构建pET-CARDS表达质粒并转入受体菌。经IPTG诱导表达的多表位拼接CARDS蛋白使用6×His单克隆抗体和人阳性血清进行了免疫印迹的检测。结果 CARDS毒素蛋白的多表位拼接抗原表达载体构建成功,诱导后表达大小为30KDa的重组蛋白,Western blot测定其能与6×His单克隆抗体和人阳性血清发生反应。结论本研究选取的CARDS毒素蛋白抗原表位具有较强的免疫活性,可为Mp感染的诊断提供新的候选抗原。 展开更多
关键词 肺炎支原体 cards毒素蛋白 多表位拼接抗原 表达 鉴定
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Integrated Assessment of Trapping Efficiency of Colored Sticky Cards and Sex Pheromone on Liriomyza spp.and Plutella xylostella 被引量:2
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作者 陈祯 郑传伟 +3 位作者 陈旷 戈毅航 刘霞 况荣平 《Agricultural Science & Technology》 CAS 2015年第2期306-310,共5页
[Objective] To evaluate the control effect of yellow sticky cards and sex pheromone on Plutella xylostella and Liriomyza spp.,which can provide reference for large area extension of the technique.[Method] The integrat... [Objective] To evaluate the control effect of yellow sticky cards and sex pheromone on Plutella xylostella and Liriomyza spp.,which can provide reference for large area extension of the technique.[Method] The integrated assessment of trapping efficiency of colored sticky cards and sex pheromone on Liriomyza spp.and Plutella xylostella was conducted by field surveys and structured interview in Tonghai County,Yunnan Province,China.[Result] The results showed that yellow sticky cards and sex pheromone have strong power of trapping Liriomyza spp.and Plutella xylostella(3 414±720 and(219±157) head/piece,respectively);the control cost by the usage of pesticide is the highest,(10 099.5±2 752.5) yuan/hm^2,yellow sticky cards and sex pheromone takes the second place,(1 125.0±465.0) yuan/hm^2,the control cost by the usage of yellow sticky cards is the lowest,(450.0 ±186.0)yuan/hm^2.Without the usage of yellow sticky cards and sex pheromone,pesticide application times and costs are(15.0±2.7) times and(12 070.5±2 136.0) yuan/hm^2;combined with usage of yellow sticky cards and sex pheromone,pesticide application times and costs reduce by 5.7 times and 4 618.5 yuan/hm^2.The ratio of trapped beneficial insects and target pests was 1 ∶1 131,which showed that the negative effect of yellow sticky cards and sex pheromone on the non-target insects was very limited.[Conclusion] The trapping approach has become popular among all the local farmers.Looking at the above factors,the trapping technology has strong application prospect and promotion value in pest control field. 展开更多
关键词 Yellow sticky cards Sex pheromone Liriomyza spp. Plutella xylostella Integrated assessment Ecological impact Trapping efficiency Application prospect
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综合控制糖尿病患者心血管疾病的多重危险因素——从UKPDS到CARDS 被引量:1
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作者 胡大一 《中国医刊》 CAS 2004年第7期59-59,共1页
关键词 综合控制 糖尿病 心血管疾病 危险因素 UKPDS cards
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CARDS研究对糖尿病调脂治疗理念的更新和启迪 被引量:1
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作者 李玲 《实用糖尿病杂志》 2005年第4期10-11,共2页
关键词 2型糖尿病患者 cards研究 治疗理念 阿妥伐他汀 调脂 降胆固醇药物 LDL-C 心血管疾病 协作研究
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退变性腰椎滑脱French分型和CARDS分型的可重复性与可信度研究 被引量:13
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作者 盛亚超 孙旭 +5 位作者 朱泽章 史本龙 孙伟翔 陈曦 袁鑫鑫 邱勇 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2017年第3期228-234,共7页
目的 :对退变性腰椎滑脱的French分型及CARDS分型进行可重复性与可信度的对比分析,探讨两种分型在退变性腰椎滑脱患者中的应用价值。方法:回顾性分析2012年1月~2016年6月期间118例腰椎退变性滑脱(L4/5 91例、L5/S1 27例)患者,其中男性26... 目的 :对退变性腰椎滑脱的French分型及CARDS分型进行可重复性与可信度的对比分析,探讨两种分型在退变性腰椎滑脱患者中的应用价值。方法:回顾性分析2012年1月~2016年6月期间118例腰椎退变性滑脱(L4/5 91例、L5/S1 27例)患者,其中男性26例,女性92例,平均年龄61.1±8.1岁。3名脊柱外科医师对患者术前X线片独自进行两次测量,分别使用French分型和临床与影像学分型(clinical and radiographic degenerative spondylolisthesis,CARDS分型)进行评估和分型,收集结果 ,作同一观察者间可重复性及不同观察者间可信度分析。应用Kappa值比较分析两种分型的差异性。结果:3位观察者使用French分型系统共进行708次(118例×3×2次)分型,包括1型261次,2型107次,3型83次,4型54次,5型203次,观察者内分型一致率80.5%~86.4%(Kappa值0.740~0.815),属于"基本可信";观察者间分型一致率为79.7%~82.2%(Kappa值0.728~0.758),属于"基本可信"。测量并分型单个患者平均花费时间约138s。CARDS分型系统共708次分型中,包括A型(A1)19次,B型(B1 90次,B2 59次)149次,C型(C1 291次,C2 108次)399次,D型(D1 98次,D2 43次)141次,观察者内总体一致率90.7%~93.2%(Kappa值0.878~0.911),属于"完全可信";观察者间总体一致率88.1%~94.1%(Kappa值0.844~0.921),属于"完全可信"。测量并分型单个患者平均花费时间约67s。结论 :两种分型系统具有较高的可重复性与可信度,CARDS分型可信度与可重复性优于French分型。 展开更多
关键词 退变性滑脱 French分型 cards分型 可信度 可重复性
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清肺透邪汤对肺炎支原体感染小鼠CARDS TX/NLRP3炎性小体相关因子表达的影响 被引量:13
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作者 王子 王雪峰 +2 位作者 张秀英 吴振起 张童 《中华中医药学刊》 CAS 北大核心 2020年第7期121-126,I0017,共7页
目的探讨清肺透邪汤对肺炎支原体(MP)感染后CARDS TX及NLRP3炎性小体相关因子的变化及相关性,试图进一步明确清肺透邪汤防治肺炎支原体肺炎(MPP)的效应靶点。方法随机将48只Balb/c幼鼠分成正常组、模型组、清肺透邪汤组、阿奇霉素组4组... 目的探讨清肺透邪汤对肺炎支原体(MP)感染后CARDS TX及NLRP3炎性小体相关因子的变化及相关性,试图进一步明确清肺透邪汤防治肺炎支原体肺炎(MPP)的效应靶点。方法随机将48只Balb/c幼鼠分成正常组、模型组、清肺透邪汤组、阿奇霉素组4组,每组12只。除正常组外,对其余3组Balb/c幼鼠采用滴鼻法进行MP感染。造模后,清肺透邪汤组每只幼鼠给予15 g/kg的对应方剂进行灌胃,1次/d,连续14 d;阿奇霉素组,每只幼鼠给予阿奇霉素90 mg/kg灌胃,1次/d,连续3 d,停药4 d,2个周期,停药期间给予蒸馏水灌胃;正常组、模型组每只幼鼠均给予0.3 mL蒸馏水灌胃。在感染后的第3、7、10、14天进行取材,运用Real-time PCR法检测肺组织CARDS TX、NLRP3、ASC及Caspase-1的表达,采用ELISA法检测血清中IL-1β表达水平,采用免疫组化法检测肺组织中NF-κB表达。结果MP感染后,幼鼠肺组织出现炎症改变,镜下可见肺泡壁增厚、肺泡上皮细胞破坏、浸润。MP感染后,幼鼠肺组织中的CARDS TX、NLRP3、ASC及Caspase-1基因表达明显升高;与模型相比,清肺透邪方组幼鼠肺组织中的CARDS TX、NLRP3、ASC及Caspase-1基因表达明显下降,其上游调控因子NF-κB减少,下游促炎因子IL-1β降低(均P<0.05)。结论清肺透邪汤可以有效地下调CARDS TX基因表达,降低MP毒力作用的主要效应靶点;初步证实了清肺透邪汤可以通过NF-κB通路调控,影响NLRP3炎性小体合成,促使IL-1β所致炎性反应减弱,可能是保护肺损伤的相关机制。 展开更多
关键词 肺炎支原体 清肺透邪汤 NLRP3 cards TX 小鼠
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退变性腰椎滑脱CARDS分型中各亚组患者在脊柱骨盆矢状位参数上的差异 被引量:1
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作者 李宗欢 刘金龙 +3 位作者 耿伟 张野 李洁 马金柱 《中国现代医生》 2021年第5期57-60,65,共5页
目的探讨退变性腰椎滑脱临床与影像学(CARDS)分型中各亚组患者在脊柱骨盆矢状位参数上的差异。方法回顾性分析2018年1月至2019年12月我院收治的92例L4~5单阶段退变性腰椎滑脱患者的临床资料。依据腰椎正侧位X线或动力位腰椎X线正侧位上... 目的探讨退变性腰椎滑脱临床与影像学(CARDS)分型中各亚组患者在脊柱骨盆矢状位参数上的差异。方法回顾性分析2018年1月至2019年12月我院收治的92例L4~5单阶段退变性腰椎滑脱患者的临床资料。依据腰椎正侧位X线或动力位腰椎X线正侧位上滑脱节段椎间隙是否后凸成角分为D型滑脱组和非D型滑脱组(即A、B、C三型)。术前、术后均测量入组患者的脊柱骨盆矢状位参数,同时采用Oswestry功能障碍指数(ODI)和腰部疼痛视觉模拟评分法(VAS)对患者生活质量进行评估。结果术前D型滑脱组LL、PI、SS均显著低于非D型滑脱组,而PT显著高于非D型滑脱组,差异有统计学意义(P<0.05)。术前D型滑脱组ODI评分和腰痛VAS评分均显著高于非D型滑脱组,差异有统计学意义(P<0.05)。结论退变性腰椎滑脱CARDS分型中D型患者与非D型患者在脊柱骨盆矢状位参数存在差异,D型可以作为一种独特的亚型进行探讨,可以推广为临床常用的术前评估分类系统之一。D型患者术前腰椎生理前凸丢失,容易表现出更严重的临床症状。 展开更多
关键词 退变性腰椎滑脱 cards分型 脊柱骨盆矢状位参数
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Christmas Cards
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作者 李国勤 《疯狂英语(初中天地)》 2002年第43期26-26,共1页
Every December,millions of Christmas cards go through the post offices.There're pictures of stars, snow or Christmas tree on the cards. In these days it's hard to think of a Christmas without cards,yet
关键词 Christmas cards
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Christmas Cards
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作者 李国勤 《疯狂英语(初中天地)》 2002年第47期26-26,共1页
Every December,millions of Christmascards go through thepost offices.There’repictures of stars。
关键词 Christmas cards
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社区获得性呼吸窘迫综合征(CARDS)肺炎支原体毒素促进THP-1细胞自噬并激活NLRP3炎性体 被引量:11
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作者 夏雯 戴晓玥 +5 位作者 吴亮 易承学 邹治情 丁龙坤 席月 许化溪 《细胞与分子免疫学杂志》 CAS CSCD 北大核心 2020年第12期1076-1082,共7页
目的研究社区获得性呼吸窘迫综合征(CARDS)肺炎支原体(Mp)毒素诱导THP-1细胞自噬以及活化含pyrin结构域核苷酸结合寡聚结构域样受体家族3(NLRP3)炎性体的能力和机制。方法采用原核表达技术获得重组CARDS(rCARDS)Mp毒素,5μg/mL和10μg/m... 目的研究社区获得性呼吸窘迫综合征(CARDS)肺炎支原体(Mp)毒素诱导THP-1细胞自噬以及活化含pyrin结构域核苷酸结合寡聚结构域样受体家族3(NLRP3)炎性体的能力和机制。方法采用原核表达技术获得重组CARDS(rCARDS)Mp毒素,5μg/mL和10μg/mL rCARDS Mp毒素作用THP-1细胞20 min、40 min、1 h、2 h和3 h。Western blot法检测THP-1细胞自噬相关蛋白beclin-1、微管相关蛋白1轻链3Ⅱ(LC3Ⅱ)和P62表达水平,实时定量PCR检测THP-1细胞NLRP3、胱天蛋白酶1(caspase-1)和白细胞介素1β(IL-1β)的mRNA水平,2',7'-二氯二氢荧光素二乙酸酯染色检测THP-1细胞活性氧(ROS)水平。结果与正常细胞对照组相比,rCARDS毒素作用1 h内,THP-1细胞beclin-1、LC3和P62表达量随着作用时间延长明显增加;rCARDS毒素作用2 h和3 h时,beclin-1、LC3和P62表达量降低。rCARDS Mp毒素作用THP-1细胞20 min和40 min时,5μg/mL、10μg/mL rCARDS Mp毒素组细胞NLRP3表达量无显著差别,但在各时间点,rCARDS Mp毒素处理的THP-1细胞NLRP3 mRNA水平均显著高于正常对照组,且作用1 h和2 h时,10μg/mL组细胞NLRP3 mRNA水平显著高于5μg/mL组,而3 h时5μg/mL组和10μg/mL组细胞NLRP3 mRNA水平均低于2 h时。rCARDS Mp毒素作用40 min、1 h和2 h时,不同剂量rCARDS Mp毒素组细胞caspase-1 mRNA水平均高于正常细胞对照组,作用40 min、1 h、2 h和3 h时,10μg/mL组细胞caspase-1 mRNA水平均显著高于5μg/mL组。与正常细胞对照组相比,rCARDS Mp毒素作用20 min和40 min时,不同剂量rCARDS Mp毒素组细胞IL-1βmRNA水平变化不明显,rCARDS Mp毒素作用1 h^3 h时,各组细胞IL-1βmRNA和ROS水平显著增加并呈剂量依赖性。结论CARDS肺炎支原体毒素可以激活THP-1细胞NLRP3炎性体活化并诱导细胞自噬。 展开更多
关键词 肺炎支原体毒素 社区获得性呼吸窘迫综合征(cards) 自噬 含pyrin结构域核苷酸结合寡聚结构域样受体家族3(NLRP3)
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Effect of Colored Sticky Cards on Non-target Insects 被引量:2
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作者 Zhen CHEN Yihang GE +1 位作者 Xia LIU Rongping KUANG 《Agricultural Science & Technology》 CAS 2015年第5期983-987,共5页
Field experiments to evaluate four different colored sticky cards for trapping non-target insects were conducted in an organic maize field in the Heinigou region of China. Yellow, blue, green, and red sticky cards wer... Field experiments to evaluate four different colored sticky cards for trapping non-target insects were conducted in an organic maize field in the Heinigou region of China. Yellow, blue, green, and red sticky cards were used to trap insects in the field. The total number of insects species caught was 54, with 3,862 individuals recorded. Over half of the specimens caught were non-target insects, including phytophagous insects, particularly dipteran species(including many mosquitoes)(50.3%), followed by target pests(37.0%), and beneficial insects(12.7%). Statistical analysis revealed a significant difference in attraction to target pests, non-target pests, and beneficial insects among treatment groups. The results showed that higher numbers of target pests(Myzus persicae Sulzer, Empoasca flavescens Fabricius, Nysius ericaecshinly Schilling) were caught on yellow sticky card traps compared with blue, green, or red sticky card traps, indicating that yellow was the best trap color for target pests, with green and blue being progressively less attractive. For non-target insects, including phytophagous insects, flies, and mosquitoes,higher numbers of were caught on blue sticky card traps compared with yellow,green, or red sticky card traps. Our study indicated that blue was the most attractive color for flies, especially for the housefly, Musca domestica Linnaeus. Our study also showed that most beneficial insects exhibited preferences to particular trap color characteristics: yellow was the most attractive color for parasitic wasps and lady beetles; blue was the most attractive color for hoverflies and honeybees. In contrast,green and red had no significant attraction to beneficial insects. 展开更多
关键词 Colored sticky cards Color trap Non-target insects Beneficial insects Natural enemies Conservation
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柴葛芩连汤对解脲脲原体肺炎小鼠肺功能及CARDS TX/NLRP3信号通路的影响 被引量:1
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作者 黄方 许诣 +4 位作者 杨雪 汪枝繁 王静 沈文婷 陈霞 《中成药》 CAS CSCD 北大核心 2023年第8期2537-2542,共6页
目的探究柴葛芩连汤对解脲脲原体肺炎模型小鼠肺功能以及CARDS TX/NLRP3信号通路的影响。方法60只小鼠分为对照组,肺炎组,柴葛芩连汤低、高剂量组和阿奇霉素组。鼻腔滴注解脲脲原体菌液进行造模,柴葛芩连汤低、高剂量组灌胃5.4、16.2 g... 目的探究柴葛芩连汤对解脲脲原体肺炎模型小鼠肺功能以及CARDS TX/NLRP3信号通路的影响。方法60只小鼠分为对照组,肺炎组,柴葛芩连汤低、高剂量组和阿奇霉素组。鼻腔滴注解脲脲原体菌液进行造模,柴葛芩连汤低、高剂量组灌胃5.4、16.2 g/kg柴葛芩连汤;阿奇霉素组灌胃90 mg/kg阿奇霉素溶液2个周期(1周期为7 d,前3 d连续灌胃阿奇霉素溶液,后4 d灌胃等量蒸馏水);对照组和肺炎组灌胃等量蒸馏水,连续14 d。采用动物肺功能分析仪检测肺功能,ELISA法检测肺泡灌洗液中炎症因子水平,HE染色观察肺组织病理变化,RT-qPCR和Western blot法检测肺组织肺炎支原体外毒素(CARDS TX)、炎症小体(NLRP3)、凋亡相关斑点样蛋白(ASC)、半胱氨酸天冬氨酸蛋白酶-1(caspase-1)的mRNA和蛋白表达。结果与对照组比较,肺炎组小鼠PEF、FEV0.1、FEF-50降低(P<0.05),IL-6、TNF-α水平及CARDS TX、NLRP3、ASC、caspase-1 mRNA和蛋白表达均升高(P<0.05),肺泡结构模糊,有炎性细胞浸润;与肺炎组比较,柴葛芩连汤各剂量组和阿奇霉素组小鼠PEF、FEV0.1与FEF-50升高(P<0.05),IL-6、TNF-α水平及CARDS TX、NLRP3、ASC、caspase-1 mRNA和蛋白表达均降低(P<0.05),肺组织病理变化有不同程度缓解。结论柴葛芩连汤可以改善解脲脲原体肺炎小鼠受损的肺功能,该作用可能与抑制CARDS TX/NLRP3信号通路有关。 展开更多
关键词 柴葛芩连汤 肺炎 解脲脲原体 cards TX NLRP3
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Progressive Randomization of a Deck of Playing Cards: Experimental Tests and Statistical Analysis of the Riffle Shuffle 被引量:1
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作者 M. P. Silverman 《Open Journal of Statistics》 2019年第2期268-298,共31页
The question of how many shuffles are required to randomize an initially ordered deck of cards is a problem that has fascinated mathematicians, scientists, and the general public. The two principal theoretical approac... The question of how many shuffles are required to randomize an initially ordered deck of cards is a problem that has fascinated mathematicians, scientists, and the general public. The two principal theoretical approaches to the problem, which differed in how each defined randomness, has led to statistically different threshold numbers of shuffles. This paper reports a comprehensive experimental analysis of the card randomization problem for the purposes of determining 1) which of the two theoretical approaches made the more accurate prediction, 2) whether different statistical tests yield different threshold numbers of randomizing shuffles, and 3) whether manual or mechanical shuffling randomizes a deck more effectively for a given number of shuffles. Permutations of 52-card decks, each subjected to sets of 19 successive riffle shuffles executed manually and by an auto-shuffling device were recorded sequentially and analyzed in respect to 1) the theory of runs, 2) rank ordering, 3) serial correlation, 4) theory of rising sequences, and 5) entropy and information theory. Among the outcomes, it was found that: 1) different statistical tests were sensitive to different patterns indicative of residual order;2) as a consequence, the threshold number of randomizing shuffles could vary widely among tests;3) in general, manual shuffling randomized a deck better than mechanical shuffling for a given number of shuffles;and 4) the mean number of rising sequences as a function of number of manual shuffles matched very closely the theoretical predictions based on the Gilbert-Shannon-Reed (GSR) model of riffle shuffles, whereas mechanical shuffling resulted in significantly fewer rising sequences than predicted. 展开更多
关键词 RANDOMIZATION of cards Number of RIFFLE Shuffles Rising Sequences GSR Model Entropy and Information
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Deuton-M Magnetic Tapes and Sheets for Cards
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作者 Tesshu Miyahara (Dainippon Ink & Chemicals, Inc. Ina-machi, Kitaadchi-gun, Saitama, 362-8577 Japan) 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2000年第2期228-231,共4页
Magnetic stripe is one of the major applications of magnetic materials. As a key component of the present card technologies magnetic stripes play reliable components for electronic data interchange in worldwide electr... Magnetic stripe is one of the major applications of magnetic materials. As a key component of the present card technologies magnetic stripes play reliable components for electronic data interchange in worldwide electronic payment systems such as financial cards, transit tickets and phone cards, etc. Magnetic stripes are available in various coercivity materials, widths, lengths, structures and colors with each types of transferable, lamination and pressure sensitive magnetic tapes of Deuton-M. Manufacturing process, structure and characteristics of Deuton-M magnetic tape and sheet are described. 展开更多
关键词 Deuton-M Magnetic Tapes and Sheets for cards CARD PET
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Can public report cards affect consumer’s private learning of quality? An evaluation of the impact of Florida hospital report cards on acute myocardial infarction patient admission patterns
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作者 Vivian Y. Wu Pai Liu 《Health》 2013年第12期2181-2189,共9页
The empirical literature on hospital report cards typically assumes that report card cannot interact with consumer’s private learning. This study examines the impact of the implementation of FL hospital quality repor... The empirical literature on hospital report cards typically assumes that report card cannot interact with consumer’s private learning. This study examines the impact of the implementation of FL hospital quality reporting system in late 2004 on hospital admission patterns using a pre-post difference-in-difference design. The estimation model allows for the possibility that report-card learning may interact with non-report-card learning. The study sample is comprised of all patients admitted to any FL hospital between 2000 and 2008 with a principal diagnosis of acute myocardial infarction (AMI). We find that hospital admission patterns for AMI patients did not respond to report card information. However, we find evidence consistent with the possibility that the implementation of a report card system may stimulate consumers (either patients or physicians) to seek higher quality hospitals through private information channels. 展开更多
关键词 HOSPITAL Report cards HOSPITAL ADMISSION Pattern PRIVATE LEARNING
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CARDS研究表明阿托伐他汀对糖尿病患者有益
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作者 郑玉斌 《中国药师》 CAS 2005年第7期602-602,共1页
辉瑞公司关于CARDS(阿托伐他汀对糖尿病人心血管疾病作用)的研究数据表明,对于低密度脂蛋白(LDL)不高的2型糖尿病患者,该药使首次发生严重心血管病事件的风险降低37%。
关键词 cards 阿托伐他汀 糖尿病 心血管病
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Domestic Agricultural Products Have "ID Cards"
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作者 Richard Zhu 《China's Foreign Trade》 2015年第3期34-34,共1页
Safety of agricultural products will not be a problem since they begin to have their own"ID Cards".Alibaba announced the launch of a program of tracing agricultural products which signals its promotion of ag... Safety of agricultural products will not be a problem since they begin to have their own"ID Cards".Alibaba announced the launch of a program of tracing agricultural products which signals its promotion of agricultural anti-fake and tracing 展开更多
关键词 agricultural tracing launch promotion PAVILION BEGIN ID cards STOPPING Northeast PADDY
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Mobile payments could replace cash, cards
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《China's Foreign Trade》 2012年第7期36-36,共1页
Mobile payments may replace cash and bank cards to become the mainstream method of payment by 2020, as reported by China Daily.
关键词 cards replace MAINSTREAM PAYMENT BANKS Daily nowad
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A “Self Experience” From the Gamified Literary Cards of Shakespeare’s Work: A Midsummer Night’s Dream
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作者 Leny Andre Pimenta Maria Regina Momesso 《Sino-US English Teaching》 2020年第3期81-87,共7页
Based on the gamified Literary Cards of the Shakespearean work A Midsummer Night’s Dream,we intend to observe,analyze,and verify in what ways the practices of reading and rewriting create effects of meaning,providing... Based on the gamified Literary Cards of the Shakespearean work A Midsummer Night’s Dream,we intend to observe,analyze,and verify in what ways the practices of reading and rewriting create effects of meaning,providing the subject reader/player to live an“experience of oneself”,being led to observe oneself,analyzing oneself,deciphering oneself,recognizing oneself as a domain of your own truth and,in this regard,your subjectivity can build your understanding of what sexuality is or highlight the repression of misunderstood desires.The reflection is based on Discourse Analysis of the French“line”,Foucaultian Studies and Freud-Lacanian Psychoanalysis,in which the postulates are about the historical determination of the processes of signification,considering that the senses are constructed in a singular way.It is understood that the gamification,used in Literary Cards,comprises an educational technology aimed not only at the apprehension of a dynamic and interpretive reading practice of oneself,but also as a facilitating resource for teachers to promote formal sexual education from elementary school on. 展开更多
关键词 literary cards GAMIFICATION experience of self SEXUALITY
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