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Anti-Aging Effect of <i>Cynara cardunculus</i>L. var. <i>Cynara scolymus</i>L. Extract in D-Galactose-Induced Skin Aging Model in Rats
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作者 Galina Sukoyan Edisher Tsivtsivadze +2 位作者 Veronika Golovach Tamara Kezeli Natalya Demina 《Pharmacology & Pharmacy》 2018年第10期428-439,共12页
The aim of the study was to evaluate the efficacy of 2% Cynara scolymus L. extracts in reverse disturbances of collagen metabolism and inflammation in D-galactose induced skin aging model in rats. D-galactose induced ... The aim of the study was to evaluate the efficacy of 2% Cynara scolymus L. extracts in reverse disturbances of collagen metabolism and inflammation in D-galactose induced skin aging model in rats. D-galactose induced aging reproduced in 48 animals of main group, and 12 rats in control group. All animals in main group were randomized for 4 groups: I. aging + saline, II - IV. different manufacturers 2% artichoke extracts (with content of chlorogenic acid 2.5%) in a dose of intradermal injection 0.13 mg twice at weeks during 4 weeks. Influence of artichoke extracts restored skin relative weight and led to an increase of solubility in neutral salt and acid, and decreased pepsin solubility collagen fraction, restored the hexosamine/collagen (hydroxyproline) ratio and decreased the activity of nuclear transcription factor (NF-kB). Local prolonged treatment with artichoke extracts improved collagen metabolism and attenuated the progression of inflammation in D-galactose induced skin aging model. 展开更多
关键词 Skin Aging Collagen Pure Water Cynara cardunculus L. VAR. Cynara scolymus L. EXTRACT Nuclear Transcription Factor KAPPA B
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Influence of Mycorrhizal Inoculation on the Salt Tolerance of Artichoke Hybrid Seedlings
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作者 Angela Campanelli Claudia Ruta Irene Morone-Fortunato Giuseppe De Mastro 《Journal of Agricultural Science and Technology(A)》 2012年第9期1071-1079,共9页
The role of mycorrhizal symbiosis in the alleviation of salinity stress induced by sodium chloride (NaCI) was investigated. Three artichoke hybrids, Madrigal F1, Opal FI, and Concerto FI (Nunhems company), were gr... The role of mycorrhizal symbiosis in the alleviation of salinity stress induced by sodium chloride (NaCI) was investigated. Three artichoke hybrids, Madrigal F1, Opal FI, and Concerto FI (Nunhems company), were grown in pot in controlled environment with two different mycorrhizal treatments (with or without Glomus viscosum). Two months after inoculation, the fungus established well on roots of the Madrigal and Opal plants with higher colonization and dependency values, instead the Concerto plants showed lower mycorrhizal dependency and colonization rate. Mycorrhizal symbiosis generally improved plant vegetative growth and sustained plant physiology increasing stomatal conductance and SPAD values. The root systems of two months old artichoke plantlets, both inoculated and non inoculated, were placed in distilled water enriched with different salt concentrations (0, 100, 150, 200, 250 mM NaCI) to study the wilting response. A visual rating system was developed defining various wilting indexes (TO, no wilting; T1, foliar damage on less than 50% of vegetal tissues of basal leaves; T2, initial wilting and foliar damage on more than 50% of vegetal tissues of basal leaves; T3, foliar damage on the apical leaves; and T4, total wilting). Mycorrhizal plants reached later the wilting indexes than non-mycorrhizal plants. Electrolyte leakage by leaves after salinity imposition was higher in non-mycorrhizal plants and the vegetal tissues were severely damaged especially in the basal leaves. The greater tolerance observed in the mycorrhizal plants could be in agreement with the improvement in growth stimulated by mycorrhizal symbiosis, which leads to the dilution of toxic ions. 展开更多
关键词 Glomus viscosum Cynara cardunculus L. subsp scolymus (L.) Hayek salt stress wilting index electrolyte leakage salttolerance.
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