Career Development of Higher Education Teachers:Opportunities,Challenges,and Strategies for Success

Career development for higher education teachers plays a crucial role in enhancing both the quality of education and the professional satisfaction of academic staff.This essay explores the various stages of career development for educators,including entry into academia,professional growth,and leadership advancement.It examines the challenges these educators face-such as the balance between teaching,research,and service-and presents strategies that institutions and individuals can adopt to foster career growth.Key factors like mentorship,continuing education,and institutional support are discussed as critical to enabling sustainable career progression.The essay concludes by underscoring the importance of ongoing development to ensure teachers can meet evolving educational demands.

Study on the Coordination Mechanism Between Higher Vocational Students’Career Development Planning and School Management

The coordination mechanism between the career development planning of vocational students and the management of vocational colleges is an important means to improve the quality of education and students’vocational competitiveness.The application of synergy theory in the field of education emphasizes the interaction and coordination of various elements in the system and pursues the optimization of overall efficiency.Based on the theory of coordination and its relevance to the management of higher vocational colleges,this paper analyzes the current development status and problems of the coordination mechanism and puts forward the strategy of building an efficient coordination mechanism designed to enhance the students’employment competitiveness,promote the all-round development,and provide theoretical and practical support for the reform and development of higher vocational education.

Research Progress on Career Development of Nursing Staff

There are few studies on career development as an exclusive concept in the field of nursing in China.Currently,research related to the career development of nursing staff primarily relies on inductive evaluation tools,and there is less systematic summarization of this research.This paper reviews the concept,evaluation tools,and influencing factors of nursing career development,aiming to provide a reference for future research in this area.

New aspects of a small GTPase RAB35 in brain development and function

In eukaryotic cells,organelles in the secretory,lysosomal,and endocytic pathways actively exchange biological materials with each other through intracellular membrane trafficking,which is the process of transporting the cargo of proteins,lipids,and other molecules to appropriate compartments via transport vesicles or intermediates.These processes are strictly regulated by various small GTPases such as the RAS-like in rat brain(RAB)protein family,which is the largest subfamily of the RAS superfamily.Dysfunction of membrane trafficking affects tissue homeostasis and leads to a wide range of diseases,including neurological disorders and neurodegenerative diseases.Therefore,it is important to understand the physiological and pathological roles of RAB proteins in brain function.RAB35,a member of the RAB family,is an evolutionarily conserved protein in metazoans.A wide range of studies using cultured mammalian cells and model organisms have revealed that RAB35 mediates various processes such as cytokinesis,endocytic recycling,actin bundling,and cell migration.RAB35 is also involved in neurite outgrowth and turnover of synaptic vesicles.We generated brain-specific Rab35 knockout mice to study the physiological roles of RAB35 in brain development and function.These mice exhibited defects in anxiety-related behaviors and spatial memory.Strikingly,RAB35 is required for the precise positioning of pyramidal neurons during hippocampal development,and thereby for normal hippocampal lamination.In contrast,layer formation in the cerebral cortex occurred superficially,even in the absence of RAB35,suggesting a predominant role for RAB35 in hippocampal development rather than in cerebral cortex development.Recent studies have suggested an association between RAB35 and neurodegenerative diseases,including Parkinson's disease and Alzheimer's disease.In this review,we provide an overview of the current understanding of subcellular functions of RAB35.We also provide insights into the physiological role of RAB35 in mammalian brain development and function,and discuss the involvement of RAB35 dysfunction in neurodegenerative diseases.

Establishment of human cerebral organoid systems to model early neural development and assess the central neurotoxicity of environmental toxins

Human brain development is a complex process,and animal models often have significant limitations.To address this,researchers have developed pluripotent stem cell-derived three-dimensional structures,known as brain-like organoids,to more accurately model early human brain development and disease.To enable more consistent and intuitive reproduction of early brain development,in this study,we incorporated forebrain organoid culture technology into the traditional unguided method of brain organoid culture.This involved embedding organoids in matrigel for only 7 days during the rapid expansion phase of the neural epithelium and then removing them from the matrigel for further cultivation,resulting in a new type of human brain organoid system.This cerebral organoid system replicated the temporospatial characteristics of early human brain development,including neuroepithelium derivation,neural progenitor cell production and maintenance,neuron differentiation and migration,and cortical layer patterning and formation,providing more consistent and reproducible organoids for developmental modeling and toxicology testing.As a proof of concept,we applied the heavy metal cadmium to this newly improved organoid system to test whether it could be used to evaluate the neurotoxicity of environmental toxins.Brain organoids exposed to cadmium for 7 or 14 days manifested severe damage and abnormalities in their neurodevelopmental patterns,including bursts of cortical cell death and premature differentiation.Cadmium exposure caused progressive depletion of neural progenitor cells and loss of organoid integrity,accompanied by compensatory cell proliferation at ectopic locations.The convenience,flexibility,and controllability of this newly developed organoid platform make it a powerful and affordable alternative to animal models for use in neurodevelopmental,neurological,and neurotoxicological studies.

Postnatal development of rat retina:a continuous observation and comparison between the organotypic retinal explant model and in vivo development

The organotypic retinal explant culture has been established for more than a decade and offers a range of unique advantages compared with in vivo experiments and cell cultures.However,the lack of systematic and continuous comparison between in vivo retinal development and the organotypic retinal explant culture makes this model controversial in postnatal retinal development studies.Thus,we aimed to verify the feasibility of using this model for postnatal retinal development studies by comparing it with the in vivo retina.In this study,we showed that postnatal retinal explants undergo normal development,and exhibit a consistent structure and timeline with retinas in vivo.Initially,we used SOX2 and PAX6 immunostaining to identify retinal progenitor cells.We then examined cell proliferation and migration by immunostaining with Ki-67 and doublecortin,respectively.Ki-67-and doublecortin-positive cells decreased in both in vivo and explants during postnatal retinogenesis,and exhibited a high degree of similarity in abundance and distribution between groups.Additionally,we used Ceh-10 homeodomain-containing homolog,glutamate-ammonia ligase(glutamine synthetase),neuronal nuclei,and ionized calcium-binding adapter molecule 1 immunostaining to examine the emergence of bipolar cells,Müller glia,mature neurons,and microglia,respectively.The timing and spatial patterns of the emergence of these cell types were remarkably consistent between in vivo and explant retinas.Our study showed that the organotypic retinal explant culture model had a high degree of consistency with the progression of in vivo early postnatal retina development.The findings confirm the accuracy and credibility of this model and support its use for long-term,systematic,and continuous observation.

An Investigation Into Career Development Contexts of University Russian Language Teachers in China(1949-2019)From the Perspective of Ecological Theory

Although much research has been conducted on the interactions between the career development of foreign language teachers and their contexts around the world,a literature review reveals that there exists scanty research on the relationship between university Russian language teachers’career development and their contexts in China since 1949.Based on relevant studies on the career development of foreign language teachers and the ecological theory,this paper involves research on the impact that different ecological systems(micro-,meso-,macro-and exo-ones)have played in the career development of Russian language teachers in China.Participants are 10 Chinese Russian teachers of different ages from different universities in different parts of China.Via literature review,narration methods and semi-structured(in-depth)interviews with the help of NVivo,this research finds that Russian language teachers’career development results from multi-faceted interactions of the following contexts:ideology,Russian language educational policies and personal factors as well as college contexts.This paper concludes with some suggestions for improving Russian language teachers’career development in China.

Predicament of College Students with Economic Difficulties in Career Development and Assistance Strategies

College students with economic difficulties are the vulnerable groups who are easy to fall into the predicament of career development. They are mainly characterized as weak career awareness,unclear self-awareness,lack of social resources,and poor comprehensive quality. This paper comprehensively analyzed the predicament of college students and causes. On the basis of causes,it came up with strategies including establishing a perfect whole-process education mechanism,strengthening psychological health and ideological and political education,actively expanding social practice internship platform,and vigorously cultivating employment competitiveness,so as to help students with economic difficulties to get out of their predicament and realize sustainable and comprehensive career development.

A Study on the Management of Career Development of Young Teachers in Higher Education Institutions from the Perspective of Career Anchors

In January 2021,six departments in China,including the Ministry of Education jointly issued the Guiding Opinions on Strengthening Reform in HEI Teacher Capacity Building for the New Era which emphasizes support for career development of young teachers.From the perspective of the career anchor theory,this paper takes human resource management as a tool to analyze organizational environment at the macro and micro levels to find out how to facilitate career development of young teachers in higher education institutions.

The restructuring of the manufacturing industry and the development of career path:The dual effect of the sharing economy

With the development of information and communications technology,the sharing economy grows dramatically.For example,the transaction value in China’s sharing economy was about 42942 billion RMB in 2018,increased of 41.6%over the previous year.Critique of the sharing economy points that the presence of the sharing economy prevents its traditional counterpart from developing sustainably by creating unemployment in traditional industries related to the sharing economy.This paper is therefore to study the dual effect of the sharing economy on the restructuring the manufacturing industry and the development of career path.By constructing an economic model,we particularly investigate the change in the labor market structure due to the presence of the sharing economy and the welfare in such a case.We show that the presence of the sharing economy can bring two effects,i.e.,DIVERSIFICATION and INCLUSIVENESS,into the workplace,which enriches the job structure and allows more labor with relative low skills to join.Regardless of the labor skill,the rapid development of the sharing economy provides new paths for their career development.In addition,we demonstrate that the above two effects crucially rely on the characteristic of CORRECTNESS of the government’s policy.The results of the theoretical model explain the necessary of promoting moderate sharing economy in terms of career development and can also be applied in the traditional manufacturing industry to explain the effect of the sharing economy on such industry.

Study on university teachers＇ career development complying with the connotative development in Shanxi province Taking young English teacher from Shaanxi University of Science and Technology for example

With the development of higher education in China, the social responsibility undertaken by higher education is becoming more and more obvious and knowledge innovation in universities, scientific research, teaching and others have played an important role for social and economic development. And the agent and practitioner of all the nature and content of these are teachers in universities and colleges which are the main power of education, teaching and research. Highly qualified team of teachers have an important value for higher education. New mode of higher education has also undergone a significant change from denotative growth gradually to connotative development concerning over personnel training and teaching quality, which bring up more requirements for the quality and ability of university teachers. Thus we will put forward a comprehensive analysis of how to comply with cormotative development and come up with new strategy of teachers＇ pro fessional development.

Development of a career-orientation scale for public health nurses

Objective: The purpose of this study was to develop a career-orientation scale for public health nurses (PHNs) and to validate the scale. Methods: Self-administered questionnaires were sent to 7170 PHNs in 10 prefectures. A retest survey was sent to 252 participants. Results: The valid responses from 2003 PHNs in the first survey were analyzed for major factors by varimax rotation. The analysis resulted in five orientation factors and 19 items being selected. The cumulative contribution ratio was 46.9%, and Cronbach’s coefficient alpha was 0.863. The exact match ratio of test-retest was 59.7% (from 47.7% to 72.1% for each item and from 12.0% to 92.0% for each participant). Conclusions: The reliability and validity of this survey were confirmed;however, further research is required to confirm the reproducibility. This scale can be used as a self-assessment tool when managers need to advise their staff on career development.

Career Development Ability:A New Orientation of Professional Degree Postgraduate Training Concept

Positioning the concept of the professional degree postgraduate cultivation with"professional development abilities"conforms to the essence of the professional degree postgraduate cultivation,clarifies the main body of the professional development,deepens the connotation of the professional degree postgraduate cultivation,and highlights the training objectives of the high-level applied talents.The cultivation of the"career development ability"should be based on the"professional knowledge and scientific research abilities",with the"problem solving ability"as the core,and should be deeply integrated with the industry.

GAMYB transcription factor LoMYB65 from lily plays a vital role in pollen development

Lily(Lilium spp.)is an important horticultural crop,but its use is limited due to serious pollen contamination problems.There are many studies on pollen development in model plants,but few on flower crops such as lilies.Gibberellin(GA)is a large class of hormones and plays an important role in plant vegetative growth and reproductive development.GAMYB is a group of the R2R3-MYB family upregulated by gibberellin,and plays an important role in anther development.Here,we isolated a novel GAMYB,named LoMYB65,from lily,which was closely related to the AtMYB65 and AtMYB33 in Arabidopsis.Fluorescence quantitative PCR results showed that LoMYB65 was mainly expressed in lily anthers.LoMYB65 could be activated by 288μmol·L^(-1)GA3treatment and the LoMYB65 protein was located in the nucleus and cytoplasm,and had transactivation in yeast and tobacco leaf cells.The conserved motif within 226 amino acids of the C-terminal of LoMYB65 contributed to its transactivation.Overexpression of LoMYB65 caused dwarf phenotype,unnormal tapetum development,less seeds of siliques in transgenic Arabidopsis plants,the transgenic plants showed partly male sterile.Simultaneously,silencing of LoMYB65 with VIGS(Virus Induced Gene Silencing)in lily anthers caused unnormal pollen development and reduced the pollen amount.Overexpression of LoMYB65 in Arabidopsis and silencing of LoMYB65 in lily resulted in decreased pollen counts,so we speculate that LoMYB65 may be dose-dependent.Overall,these findings suggest that LoMYB65 may play an important role in anther development and pollen formation in lily.LoMYB65 may provide a useful candidate gene for pollenless breeding of lily.

Use of cognitive-behavioral career coaching to reduce work anxiety and depression in public employees

BACKGROUND Public employees worldwide are increasingly concerned about work anxiety and depression.Cognitive-behavioral career coaching has emerged as a promising strategy for addressing these mental health disorders,which can negatively impact on a person's overall well-being and performance.AIM To examine whether cognitive-behavioral career coaching reduces work anxiety and depression among Nigerian public employees.METHODS A total of 120 public employees(n=60)suffering from severe anxiety and depression were randomly assigned to the treatment or control groups in this study.Cognitive behavioral coaching was provided twice a week to those in the treatment group,whereas no treatment was given to those in the control group.As part of the study,the Hamilton Anxiety Rating Scales and Beck Depression Inventory were used to collect data.RESULTS Analysis of covariance of the data from participants indicates a significant effect of cognitive-behavioral career coaching on work anxiety and depression.CONCLUSION Insights into the underlying mechanisms by which cognitive behavior career coaching exerts its effects have been gained from this study.Also,the study has gathered valuable data that can inform future practice and guide the development of strategies for supporting mental health at work.

Conventional Geothermal Systems and Unconventional Geothermal Developments: An Overview

This paper provides an overview of conventional geothermal systems and unconventional geothermal developments as a common reference is needed for discussions between energy professionals. Conventional geothermal systems have the heat, permeability and fluid, requiring only drilling down to °C, normal heat flow or decaying radiogenic granite as heat sources, and used in district heating. Medium-temperature (MT) 100°C - 190°C, and high-temperature (HT) 190°C - 374°C resources are mostly at plate boundaries, with volcanic intrusive heat source, used mostly for electricity generation. Single well capacities are °C - 500°C) and a range of depths (1 m to 20 Km), but lack permeability or fluid, thus requiring stimulations for heat extraction by conduction. HVAC is 1 - 2 m deep and shallow geothermal down to 500 m in wells, both capturing °C, with °C are either advanced by geothermal developers at <7 Km depth (Enhanced Geothermal Systems (EGS), drilling below brittle-ductile transition zones and under geothermal fields), or by the Oil & Gas industry (Advanced Geothermal Systems, heat recovery from hydrocarbon wells or reservoirs, Superhot Rock Geothermal, and millimeter-wave drilling down to 20 Km). Their primary aim is electricity generation, relying on closed-loops, but EGS uses fractures for heat exchange with earthquake risks during fracking. Unconventional approaches could be everywhere, with shallow geothermal already functional. The deeper and hotter unconventional alternatives are still experimental, overcoming costs and technological challenges to become fully commercial. Meanwhile, the conventional geothermal resources remain the most proven opportunities for investments and development.

Development and technology status of energy storage in depleted gas reservoirs

Utilizing energy storage in depleted oil and gas reservoirs can improve productivity while reducing power costs and is one of the best ways to achieve synergistic development of"Carbon Peak–Carbon Neutral"and"Underground Resource Utiliza-tion".Starting from the development of Compressed Air Energy Storage(CAES)technology,the site selection of CAES in depleted gas and oil reservoirs,the evolution mechanism of reservoir dynamic sealing,and the high-flow CAES and injection technology are summarized.It focuses on analyzing the characteristics,key equipment,reservoir construction,application scenarios and cost analysis of CAES projects,and sorting out the technical key points and existing difficulties.The devel-opment trend of CAES technology is proposed,and the future development path is scrutinized to provide reference for the research of CAES projects in depleted oil and gas reservoirs.

BMPRⅡ^(+)neural precursor cells isolated and characterized from organotypic neurospheres:an in vitro model of human fetal spinal cord development

Roof plate secretion of bone morphogenetic proteins(BMPs)directs the cellular fate of sensory neurons during spinal cord development,including the formation of the ascending sensory columns,though their biology is not well understood.Type-ⅡBMP receptor(BMPRⅡ),the cognate receptor,is expressed by neural precursor cells during embryogenesis;however,an in vitro method of enriching BMPRⅡ^(+)human neural precursor cells(hNPCs)from the fetal spinal cord is absent.Immunofluorescence was undertaken on intact second-trimester human fetal spinal cord using antibodies to BMPRⅡand leukemia inhibitory factor(LIF).Regions of highest BMPRⅡ^(+)immunofluorescence localized to sensory columns.Parenchymal and meningeal-associated BMPRⅡ^(+)vascular cells were identified in both intact fetal spinal cord and cortex by co-positivity with vascular lineage markers,CD34/CD39.LIF immunostaining identified a population of somas concentrated in dorsal and ventral horn interneurons,mirroring the expression of LIF receptor/CD118.A combination of LIF supplementation and high-density culture maintained culture growth beyond 10 passages,while synergistically increasing the proportion of neurospheres with a stratified,cytoarchitecture.These neurospheres were characterized by BMPRⅡ^(+)/MAP2ab^(+/–)/βⅢ-tubulin^(+)/nestin^(–)/vimentin^(–)/GFAP^(–)/NeuN^(–)surface hNPCs surrounding a heterogeneous core ofβⅢ-tubulin^(+)/nestin^(+)/vimentin^(+)/GFAP^(+)/MAP2ab^(–)/NeuN^(–)multipotent precursors.Dissociated cultures from tripotential neurospheres contained neuronal(βⅢ-tubulin^(+)),astrocytic(GFAP+),and oligodendrocytic(O4+)lineage cells.Fluorescence-activated cell sorting-sorted BMPRⅡ^(+)hNPCs were MAP2ab^(+/–)/βⅢ-tubulin^(+)/GFAP^(–)/O4^(–)in culture.This is the first isolation of BMPRⅡ^(+)hNPCs identified and characterized in human fetal spinal cords.Our data show that LIF combines synergistically with high-density reaggregate cultures to support the organotypic reorganization of neurospheres,characterized by surface BMPRⅡ^(+)hNPCs.Our study has provided a new methodology for an in vitro model capable of amplifying human fetal spinal cord cell numbers for>10 passages.Investigations of the role BMPRⅡplays in spinal cord development have primarily relied upon mouse and rat models,with interpolations to human development being derived through inference.Because of significant species differences between murine biology and human,including anatomical dissimilarities in central nervous system(CNS)structure,the findings made in murine models cannot be presumed to apply to human spinal cord development.For these reasons,our human in vitro model offers a novel tool to better understand neurodevelopmental pathways,including BMP signaling,as well as spinal cord injury research and testing drug therapies.

The Impact of Supervisory Career Support on Employees’Well-Being:A Dual Path Model of Opportunity and Ability

Background:In the pursuit of fostering employees’well-being,leaders are recognized as playing a vital role.However,so far,most of the existing research has focused on leadership behavior and the superficial interaction between leaders and members but has unexpectedly ignored the specific supporting role of supervisors in the career development of employees,that is,supervisory career support.Additionally,the internal mechanism of how career support from supervisors is related to and promotes employees’wellbeing is still unclear.Based on social cognitive career theory(SCCT),this study aimed to explore whether,how,and when supervisory career support affects employee well-being by introducing the two paths of‘career prospect’and‘career confidence.’Methods:During July 2023,this study employed a cross-sectional design.We gathered participants from corporate situated in Southern China.Results:Results based on a large sample of 14,533 employees showed that supervisory career support was positively related to employees’well-being through the dual path of career prospects(opportunity)and career confidence(ability).Employees high in proactive personality experienced the above positive effects most.Conclusion:This study provides meaningful implications for managers to implement personalized support strategies to improve employees’well-being.