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Phacoemulsification versus small incision cataract surgery in patients with uveitis 被引量:8
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作者 Rahul Bhargava Prachi Kumar +2 位作者 Shiv Kumar Sharma Manoj Kumar Avinash Kaur 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2015年第5期965-970,共6页
AIMTo compare the safety and efficacy of phacoemulsification and small incision cataract surgery (SICS) in patients with uveitic cataract.METHODSIn a prospective, randomized multi-centric study, consecutive patients w... AIMTo compare the safety and efficacy of phacoemulsification and small incision cataract surgery (SICS) in patients with uveitic cataract.METHODSIn a prospective, randomized multi-centric study, consecutive patients with uveitic cataract were randomized to receive phacoemulsification or manual SICS by either of two surgeons well versed with both the techniques. A minimum inflammation free period of 3mo (defined as less than 5 cells per high power field in anterior chamber) was a pre-requisite for eligibility for surgery. Superior scleral tunnel incisions were used for both techniques. Improvement in visual acuity post-operatively was the primary outcome measure and the rate of post-operative complications and surgical time were secondary outcome measures, respectively. Means of groups were compared using t-tests. One way analysis of variance (ANOVA) was used when there were more than two groups. Chi-square tests were used for proportions. Kaplan Meyer survival analysis was done and means for survival time was estimated at 95% confidence interval (CI). A P value of &#x0003c;0.05 was considered statistically significant.RESULTSOne hundred and twenty-six of 139 patients (90.6%) completed the 6-month follow-up. Seven patients were lost in follow up and another six excluded due to either follow-up less than six months (n=1) or inability implant an intraocular lens (IOL) because of insufficient capsular support following posterior capsule rupture (n=5). There was significant improvement in vision after both the procedures (paired t-test; P&#x0003c;0.001). On first postoperative day, uncorrected distance visual acuity (UDVA) was 20/63 or better in 31 (47%) patients in Phaco group and 26 (43.3%) patients in SICS group (P=0.384). The mean surgically induced astigmatism (SIA) was 0.86&#x000b1;0.34 dioptres (D) in the phacoemulsification group and 1.16&#x000b1;0.28 D in SICS group. The difference between the groups was significant (t-test, P=0.002). At 6mo, corrected distance visual acuity (CDVA) was 20/60 or better in 60 (90.9%) patients in Phaco group and 53 (88.3%) in the manual SICS group (P=0.478). The mean surgical time was significantly shorter in the manual SICS group (10.8&#x000b1;2.9 versus 13.2&#x000b1;2.6min) (P&#x0003c;0.001). Oral prednisolone, 1 mg/kg body weight was given 7d prior to surgery, continued post-operatively and tapered according to the inflammatory response over 4-6wk in patients with previously documented macular edema, recurrent uveitis, chronic anterior uveitis and intermediate uveitis. Rate of complications like macular edema (Chi-square, P=0.459), persistent uveitis (Chi-square, P=0.289) and posterior capsule opacification (Chi-square, P=0.474) were comparable between both the groups.CONCLUSIONManual SICS and phacoemulsification do not differ significantly in complication rates and final CDVA outcomes. However, manual SICS is significantly faster. It may be the preferred technique in settings where surgical volume is high and access to phacoemulsification is limited, such as in eye camps. It may also be the appropriate technique for uveitic cataract under such circumstances. 展开更多
关键词 small incision cataract surgery PHACOEMULSIFICATION uveitis corrected distance visual acuity uncorrected distance visual acuity
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Therapeutic potential of pupilloplasty combined with phacomulsification and intraocular lens implantation against uveitis-induced cataract
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作者 Hui Lu Dou-Dou Chen Si-Quan Zhu 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2022年第10期1598-1603,共6页
AIM: To evaluate the therapeutic effect of pupilloplasty combined with phacomulsification and intraocular lens implantation(PPI) in uveitis-induced cataract.METHODS: Total 28 patients with uveitis-induced cataract wer... AIM: To evaluate the therapeutic effect of pupilloplasty combined with phacomulsification and intraocular lens implantation(PPI) in uveitis-induced cataract.METHODS: Total 28 patients with uveitis-induced cataract were enrolled. Within 3 mo before the PPI, 7 cases accompanied with glaucoma maintained carteolol hydrochloride for lowering intraocular pressure, and 1 case maintained glucocorticoid for anti-inflammation. The baseline characteristics, treatment processes, and outcomes of enrolled cases were retrospectively analyzed. Hematoxylin and eosin(HE) staining was performed to reveal the histopathological changes of iris tissues.RESULTS: Iris hemorrhage was the only intraoperative complication observed in 2 cases. After the surgery, normal intraocular pressure, right position of intraocular lens, and improved visual gain [best corrected visual acuity(BCVA)>0.5] were achieved. Postoperative keratic precipitates was observed in 2 cases, which was recovered within 1 wk. During the follow-up of 5-10 y, no recurrence of uveitis was found in 27 cases(96.43%). Uveitis only recurred in one case with the onset of ankylosing spondylitis. HE staining showed iris stroma(all samples), pigment cell hyperplasia in pigment epithelium(n=9) and stroma(n=19), inflammatory cell infiltration in iris(n=7), and neovascularization in iris surface(n=2).CONCLUSION: PPI improves the visual gain and prevents the long-term recurrence of uveitis in patients with uveitis-induced cataract, including those with preoperative intraocular pressure abnormality(glaucoma) and inflammation(active uveitis). Uveitis presents stroma atrophy, pigment cell hyperplasia, and inflammatory cell infiltration, even in a quiet state. 展开更多
关键词 uveitis cataract GLAUCOMA HISTOPATHOLOGY RECURRENCE
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Surgical outcomes of complicated cataract with pediatric trematode granulomatous uveitis
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作者 Mahmoud M.Farouk Amr Mounir +2 位作者 Mortada Ahmed Abozaid Engy Mohamed Mostafa Marwa Mahmoud Abdellah 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2023年第3期354-360,共7页
AIM:To describe the clinical characteristics and surgical outcomes of complicated cataract with pediatric trematodal granulomatous uveitis(TGU).METHODS:Patients of cataract with TGU in the membranous(inactive) stage u... AIM:To describe the clinical characteristics and surgical outcomes of complicated cataract with pediatric trematodal granulomatous uveitis(TGU).METHODS:Patients of cataract with TGU in the membranous(inactive) stage underwent cataract surgery with intraocular lens(IOL) implantation.Preoperative history and ophthalmic examination were conducted for all cases,whereas Schimphlug imaging and corneal topography were done for some patients.Postoperative follow up was done on the 1st,2nd,and 5th postoperative days after surgery.Then,it was done at least at one,three,and six months postoperatively.Intraoperative and postoperative complications and the methods of their management were reported.RESULTS:Twelve eyes of 12 male children were included in this study ranging from 8 to 16y.The mean best corrected Snellen visual acuity(BCVA) was significantly improved from 0.09±0.06 preoperatively to 0.37±0.11 at the final visit 6mo postoperatively(P<0.001).Schimphlug imaging and corneal topography showed flattening of the anterior surface of the inferior cornea.Intraoperative difficulties and complications included the poor dilatability of the drown down pupil,strong posterior synechia between the anterior lens capsule and the iris at the site of the inferior retrocorneal vascularized membrane and hyphema.All cases underwent primary hydrophobic IOL implantation.CONCLUSION:Surgery for this type of cataract is relatively safe and effective.It is associated with some specific difficulties and complications that should be considered during surgery and follow up. 展开更多
关键词 complicated cataract trematode granulomatous uveitis surgical outcomes
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Clinical Outcome of Intracameral Dexamethasone in Paediatric Cataract Surgery in a Nigerian Missionary Hospital
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作者 S. O. Abu A. A. Onua B. Fiebai 《Open Journal of Ophthalmology》 2018年第4期224-231,共8页
Paediatric cataract surgery is associated with several complications among which is high ocular inflammatory response. Conventionally immediate post-operative subconjunctival steroid with adjuvant systemic and frequen... Paediatric cataract surgery is associated with several complications among which is high ocular inflammatory response. Conventionally immediate post-operative subconjunctival steroid with adjuvant systemic and frequent topical steroids have been used to control post-operative inflammation. Studies have reported the advantage of intracameral dexamethasone in decreasing postoperative inflammation. Aim: To evaluate the clinical outcome of intracameral dexamethasone in paediatric cataract surgery in Evangelical Church of West Africa (ECWA) Eye Hospital, Kano. Method: This was a prospective study of 694 paediatric cataract surgeries from January 2006 to December 2014. All the patients were given intracameral dexamethasone 0.4 mg (0.1 ml) immediately after surgery. Each patient had surgical intervention on one eye. Evaluation was done on first, third postoperative day, one week and four weeks later (follow up visits). Outcomes were measured on the fourth week post-operation. Examination of children was done with help of slit lamp for cells, flare or any other sign of inflammation. In case of non-cooperative children examination was done with microscope under sedation/general anaesthesia for fibrinous reaction, exudative membrane, posterior synechiae and red reflex. Results: There were total of 694 patients with age range of 0 to 11 years. Mean age of participants was 2.03 ± 2.5 years. The mean duration of cataract before presentation to the hospital was 5.7 ± 4.3 months with a range of 0 to 16 months. Post operative complications, likely to be associated with intracameral dexamethasone were corneal opacity (0.6%) and raised intraocular pressure (12.5%). In 31 patients (4.5%) there was no post operative complication. Conclusion: Intracameral injection of dexamethasone has a role in preventing immediate postoperative anterior uveitis in paediatric cataract but may not be without complication. 展开更多
关键词 INTRACAMERAL DEXAMETHASONE PAEDIATRIC cataract Surgery Postoperative uveitis
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Phacoemulsification in Patients with Secondary Glaucoma Caused by Uveitis 被引量:1
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作者 Mingkai Lin, Jian Ge, Yizhi Liu, Yuqing Lan, Yehong ZhouZhongshan Ophthalmic Center, Sun Yat-Sen University of Medical Sciences. Guangzhou, 510060, China 《Eye Science》 CAS 2001年第1期8-10,共3页
Purposes: To evaluate the effect of phacoemulsification in the patients with uveitis,secondary glaucoma and complicated cataract. Methods: Phacoemulsification and implantation of a foldable intraocular len was perform... Purposes: To evaluate the effect of phacoemulsification in the patients with uveitis,secondary glaucoma and complicated cataract. Methods: Phacoemulsification and implantation of a foldable intraocular len was performed in 12 patients(13 eyes) with uveitis, secondary glaucoma and complicated cataract. The complications, intraocular pressures (IOP), and visual acuity were observed postoperatively. Results: No severe complication was found in the patients postoperatively or within the operation procedure. The visual acuity was improved after the operation ( P < 0.05) .The intraocular pressures and/or the number of antiglaucoma medications reduced in 3months of the follow-up time. Conclusion: phacoemulsification is the best way to treat the patients with secondary glaucoma and complicated cataract caused by uveitis. Eye Science 2001; 17: 8 ~ 10. 展开更多
关键词 晶状体囊炎 青光眼 并发症 葡萄膜炎 病因
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Presumed Acquired Retinal Astrocytoma in Association with Anterior Uveitis 被引量:1
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作者 Xibin Zhou Houbin Huang Yifei Huang 《Eye Science》 CAS 2013年第1期51-54,共4页
Purpose:To report a case of presumed acquired retinal astrocytoma in association with anterior uveitis. Methods:A 29-year-old man presented with mutton fat keratic precipitates in the inferiorlower cornea,with complic... Purpose:To report a case of presumed acquired retinal astrocytoma in association with anterior uveitis. Methods:A 29-year-old man presented with mutton fat keratic precipitates in the inferiorlower cornea,with complicated cataract and a circumscribed,solitary,yellowish-white retinal lesion in the right eye.Phacoemulsification with intraocular lens implantation was performed, with election to observeand the lesion was observed periodically. The lesion was followed for over two years without any change in size, shape or, and appearance. The anterior uveitis has not recurred at the time of writing. Results:Systemic medical and laboratory evaluations, including chest computed tomography,cranial magnetic resonance imaging,and serum angiotensin converting enzyme level, were normal. The characteristic fundus, FA,OCT scan, ultrasound scan,and lack of other contributory laboratory findings strongly supported the diagnosis of acquired retinal astrocytoma in this patient. Conclusion:We hypothesized that anterior uveitis may contribute to the growth and maintenance of retinal lesions. (Eye Science 2013; 28:51-54) 展开更多
关键词 星形细胞 视网膜 葡萄 收购 计算机断层扫描 血管紧张素转化酶 协会 实验室评估
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超声生物显微镜在儿科常见眼病中的应用进展
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作者 彭彩霞 罗悦隽 王丹丹 《医学影像学杂志》 2024年第6期134-137,共4页
超声生物显微镜(UBM)是对复杂虹膜-睫状复合体进行高分辨率成像的一种非侵入性超声技术,尤其适用于角膜混浊及其他屈光介质不清的眼前段疾病。UBM成像现已广泛应用于成人,而在儿科人群中,因绝大部分眼前节疾病伴有角膜混浊,且无法提供... 超声生物显微镜(UBM)是对复杂虹膜-睫状复合体进行高分辨率成像的一种非侵入性超声技术,尤其适用于角膜混浊及其他屈光介质不清的眼前段疾病。UBM成像现已广泛应用于成人,而在儿科人群中,因绝大部分眼前节疾病伴有角膜混浊,且无法提供详细病史,检查依存性差,因此UBM在小儿眼科中显得至关重要。本文就UBM在儿科常见眼病中的应用进展进行综述。 展开更多
关键词 原发性先天性青光眼 葡萄膜炎 先天性白内障 肿瘤样病变 超声生物显微镜
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一氧化氮及一氧化氮合酶在眼部疾病中的研究进展
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作者 贺婷 李文慧 +1 位作者 田庆梅 解孝锋 《国际眼科杂志》 CAS 2024年第12期1917-1921,共5页
一氧化氮(NO)是在一氧化氮合酶(NOS)催化下,由内皮细胞产生并存在于人体多器官组织中的内皮源性舒张因子,同时也是介导生物体内多种生理病理过程的关键气体信号分子。NO与NOS具有调节人体血管张力,舒张平滑肌,参与炎症反应,传递神经递... 一氧化氮(NO)是在一氧化氮合酶(NOS)催化下,由内皮细胞产生并存在于人体多器官组织中的内皮源性舒张因子,同时也是介导生物体内多种生理病理过程的关键气体信号分子。NO与NOS具有调节人体血管张力,舒张平滑肌,参与炎症反应,传递神经递质等多方面作用,已在一定范围内用于疾病的治疗。近年来眼科疾病发生多呈上升态势,不同程度降低患者生活质量,但大多数疾病治疗方式有限。研究发现,在眼球多部位组织中均可检测到NO与NOS的存在,两者参与眼表及眼底多种疾病的发生及转归过程。文章将NO、NOS与眼部疾病的相关性进行综述,分析其在疾病发生发展中的机制作用,为眼科疾病的临床治疗提供新思路。 展开更多
关键词 一氧化氮 一氧化氮合酶 白内障 青光眼 葡萄膜炎 近视
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超声乳化摘除白内障治疗葡萄膜炎继发性青光眼的疗效分析
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作者 涂晶晶 《智慧健康》 2024年第21期52-54,58,共4页
目的 观察超声乳化摘除白内障治疗葡萄膜炎继发性青光眼的疗效。方法 选取2022年1—12月本院接诊的葡萄膜炎继发性青光眼伴白内障患者84例为研究对象,并按照随机数字表法分为对照组和观察组,每组42例。其中,对照组使用常规白内障囊外摘... 目的 观察超声乳化摘除白内障治疗葡萄膜炎继发性青光眼的疗效。方法 选取2022年1—12月本院接诊的葡萄膜炎继发性青光眼伴白内障患者84例为研究对象,并按照随机数字表法分为对照组和观察组,每组42例。其中,对照组使用常规白内障囊外摘除治疗,观察组使用超声乳化摘除白内障治疗。观察两组眼压和视力情况、角膜内皮细胞相关指标情况、临床疗效及并发症情况。结果 治疗前,两组患者视力、眼压比较,差异无统计学意义(P>0.05);治疗后,观察组眼压低于对照组,观察组视力高于对照组,差异有统计学意义(P<0.05)。治疗前,两组角膜中心厚度、平均细胞面积、六角形细胞比率、细胞面积变异系数、角膜内皮细胞密度比较,差异无统计学意义(P>0.05);治疗后,观察组角膜中心厚度、平均细胞面积、六角形细胞比率、细胞面积变异系数高于对照组,观察组角膜内皮细胞密度低于对照组,差异有统计学意义(P<0.05)。观察组治疗有效率高于对照组,差异无统计学意义(P>0.05);观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论 葡萄膜炎继发性青光眼伴白内障患者采用超声乳化摘除白内障治疗效果理想,可以明显改善患者眼压、视力、角膜内皮细胞情况,临床疗效理想,并发症发生率低,可推广应用。 展开更多
关键词 葡萄膜炎 超声乳化摘除白内障治疗 青光眼 视力 眼压
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Intralenticular metallic foreign body: a case report 被引量:1
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作者 S C Reddy 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2011年第3期326-328,共3页
A case of retained intralenticular iron piece with signs of mild anterior uveitis at the time of presentation is reported in a 45 year-old man. His vision improved with topical cycloplegics and corticosteroids. After ... A case of retained intralenticular iron piece with signs of mild anterior uveitis at the time of presentation is reported in a 45 year-old man. His vision improved with topical cycloplegics and corticosteroids. After six months, his vision deteriorated grossly due to cataract formation. He regained good vision following removal of foreign body, extracapsular extraction with posterior chamber intraocular lens implantation. This case highlights the conservative management of the condition till the patient develops cataract resulting in visual disability; and good visual recovery following cataract surgery with intraocular lens implantation. 展开更多
关键词 intralenticular foreign body anterior uveitis traumatic cataract penetrating eye injury
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葡萄膜炎并发性白内障瞳孔粘连的手术治疗
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作者 唐知进 《临床医药实践》 2008年第17期772-774,共3页
目的:探讨葡萄膜炎并发白内障虹膜后粘连小瞳孔状态下手术技巧、时机及疗效。方法:对45例56眼葡萄膜炎并发性白内障小瞳孔患者,在葡萄膜炎控制稳定,炎症消退3个月后,借助粘弹剂分离虹膜后粘连或施行瞳孔环型扩张,再行白内障超声乳化或... 目的:探讨葡萄膜炎并发白内障虹膜后粘连小瞳孔状态下手术技巧、时机及疗效。方法:对45例56眼葡萄膜炎并发性白内障小瞳孔患者,在葡萄膜炎控制稳定,炎症消退3个月后,借助粘弹剂分离虹膜后粘连或施行瞳孔环型扩张,再行白内障超声乳化或囊外摘出及人工晶体植入。结果:术后48眼(85%)视力较术前提高,其中≥0.5者19眼,0.3~0.5者13眼,0.1~0.3者16眼。瞳孔圆形或椭圆形。术后眼压均控制在正常范围。结论:葡萄膜炎并发性白内障虹膜后粘连,可使瞳孔扩大成圆形或椭圆型,有利于实施白内障超声乳化或囊外摘除,且瞳孔括约肌不受损伤,避免术后眩光,可获得良好视力,术中、术后并发症减少。 展开更多
关键词 uveitis COMPLICATED cataract SMALL PUPIL intraocul
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葡萄膜炎并发白内障术后前房注射地塞米松的疗效观察 被引量:12
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作者 张君 杨炜 +2 位作者 张奕霞 赵新荣 齐新刚 《国际眼科杂志》 CAS 2013年第4期749-751,共3页
目的:探索白内障摘除术后前房注射0.1mL地塞米松对葡萄膜炎并发白内障患者术后的影响。方法:试验组术后前房注射0.1mL地塞米松,对照组前房未注射地塞米松,观察两组术后炎症反应。结果:术后前2d两组患者视力间差别有统计学意义(P<0.0... 目的:探索白内障摘除术后前房注射0.1mL地塞米松对葡萄膜炎并发白内障患者术后的影响。方法:试验组术后前房注射0.1mL地塞米松,对照组前房未注射地塞米松,观察两组术后炎症反应。结果:术后前2d两组患者视力间差别有统计学意义(P<0.05),术后第1d角膜水肿程度两组间有统计学差异(P<0.05),前房闪辉差异有统计学意义(P<0.05),且试验组术后患者视力提高者百分比高于对照组。结论:葡萄膜炎并发白内障患者行白内障超声乳化+人工晶状体植入术,术毕前房注射0.1mL地塞米松者可减轻短期术后炎症反应,可更早提高患者视力,对患者术后短期眼压未见明显影响。 展开更多
关键词 葡萄膜炎 并发性白内障 地塞米松 前房注射
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葡萄膜炎并发白内障术中前房注射长效糖皮质激素的疗效 被引量:12
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作者 李锐 袁慧敏 +1 位作者 刘钊臣 李勇 《国际眼科杂志》 CAS 2016年第12期2254-2257,共4页
目的:研究术中前房注射长效糖皮质激素是否能提高葡萄膜炎并发白内障手术的疗效,以期为临床诊疗提供参考。方法:分析2013-01/2015-01我院收治的接受手术治疗的葡萄膜炎并发白内障患者68例71眼的临床资料。依据治疗方法的不同分为观察... 目的:研究术中前房注射长效糖皮质激素是否能提高葡萄膜炎并发白内障手术的疗效,以期为临床诊疗提供参考。方法:分析2013-01/2015-01我院收治的接受手术治疗的葡萄膜炎并发白内障患者68例71眼的临床资料。依据治疗方法的不同分为观察组(术中前房注射曲安奈德,35例37眼)及对照组(术中不注射曲安奈德,33例34眼)。对比两组患者的疗效。结果:观察组术后1mo矫正视力〉0.5比例显著高于对照组,差异有统计学意义(χ~2=4.094,P=0.043)。两组术前及术后眼压比较均无统计学意义(P〉0.05)。观察组患者术后前房炎症反应低于对照组,差异具有统计学意义(χ~2=15.900,P=0.001);术后1wk,观察组房水内SOD水平显著高于对照组,差异有统计学意义(P〈0.05),而MDA及TNF-α水平显著低于对照组水平,差异有统计学意义(P〈0.05)。观察组术后1a累积复发率显著低于对照组,差异有统计学意义(14%,5/35 vs 3%,11/33;Log-rankχ~2=4.004,P=0.045)。结论:术中前房注射曲安奈德可显著提高葡萄膜炎并发白内障患者手术的疗效。 展开更多
关键词 曲安奈德 葡萄膜炎 白内障 手术 复发
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葡萄膜炎并发白内障小瞳孔下行超声乳化及人工晶状体植入术的疗效观察 被引量:17
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作者 高付林 胡莲娜 +1 位作者 赵军 麻南 《眼科新进展》 CAS 北大核心 2009年第9期700-702,共3页
目的探讨葡萄膜炎并发白内障在小瞳孔下行白内障超声乳化及人工晶状体植入术的手术方法及临床效果。方法对17例(30眼)葡萄膜炎并发性白内障、瞳孔直径2.0~4.0mm的患者,用显微虹膜拉钩扩大瞳孔,黏弹剂分离虹膜后粘连,完成白内障超声乳... 目的探讨葡萄膜炎并发白内障在小瞳孔下行白内障超声乳化及人工晶状体植入术的手术方法及临床效果。方法对17例(30眼)葡萄膜炎并发性白内障、瞳孔直径2.0~4.0mm的患者,用显微虹膜拉钩扩大瞳孔,黏弹剂分离虹膜后粘连,完成白内障超声乳化及人工晶状体植入术,观察手术前后患者瞳孔、最佳矫正视力及并发症情况,并观察眼底情况。结果术中扩大瞳孔至4.0~6.0mm,手术顺利进行,术后第1天平均瞳孔直径为(3.70±0.31)mm,术后3个月、6个月瞳孔直径为(3.30±0.27)mm;术后6个月矫正视力≥0.5者24眼,0.3~0.4者3眼,0.1~0.2者2眼,小于0.1者1眼;术后黄斑水肿3眼,后发性白内障2眼,葡萄膜炎复发3眼。结论葡萄膜炎并发白内障在小瞳孔下行白内障超声乳化术,术中应用显微虹膜拉钩有利于扩大瞳孔,术后反应小,瞳孔近似圆形,可获得良好的矫正视力。 展开更多
关键词 葡萄膜炎 小瞳孔 白内障 超声乳化术 显微虹膜拉钩
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手法扩张后不同瞳孔直径对瞳孔闭锁并发性白内障疗效的影响 被引量:10
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作者 王婷 刘军彩 +1 位作者 王姝婷 史伟云 《中华实验眼科杂志》 CAS CSCD 北大核心 2013年第6期592-596,共5页
背景瞳孔闭锁增加了白内障超声乳化手术的难度,瞳孔扩张不当容易产生诸多并发症,探索合适的瞳孔扩张直径和方法对提高手术疗效十分重要。目的评价手法扩张瞳孔术对瞳孔闭锁并发性白内障患者术后瞳孔功能的影响。方法收集2006年5月至2... 背景瞳孔闭锁增加了白内障超声乳化手术的难度,瞳孔扩张不当容易产生诸多并发症,探索合适的瞳孔扩张直径和方法对提高手术疗效十分重要。目的评价手法扩张瞳孔术对瞳孔闭锁并发性白内障患者术后瞳孔功能的影响。方法收集2006年5月至2012年5月在山东省眼科研究所诊治的陈旧性葡萄膜炎致瞳孔闭锁或膜闭并发性白内障患者30例38眼,对患眼行手法扩张瞳孑L术治疗瞳孑L闭锁并发性白内障。按照患眼术中瞳孔扩张的大小分为瞳孔扩大≥6.0mm组15眼和瞳孔扩大4.5~5.5mm组23眼,同时行白内障超声乳化摘出联合人工晶状体(IOL)植人术。手术中首先撕除瞳孔区机化膜,然后应用23G眼科显微剪对瞳孔领的机化纤维条带做均匀锯齿状剪开,左右手虹膜拉钩多点扩张瞳孔。手术后局部与全身应用糖皮质激素药物和非甾体类抗炎药物,局部应用扩张瞳孔药物。术后随访3个月,分析不同瞳孔直径对术眼视力、并发症、畏光症状、眼压等情况的影响。结果瞳孔扩大≥6.0mm组手术中扩张瞳孑L至(6.9±0.4)mm,瞳孔扩大4.5~5.5mm组扩张瞳孔至(5.1±0.3)mm,两组差异有统计学意义(t=16.100,P=0.000)。术后3个月瞳孔扩大≥6.0mm组瞳孔直径为(4.9±0.4)NINl,瞳孔缘有不同程度的撕裂口;瞳孔扩大4.5~5.5mm组瞳孔直径为(3.5±0.5)mm,瞳孔缘撕裂口少见,2个组瞳孔直径的差异有统计学意义(t=9.820,P=0.000)。瞳孔扩大≥6.0mm组瞳孔对光反射迟钝或消失者11眼,明显高于瞳孔扩大4.5~5.5mm组的6眼,差异有统计学意义(x2=8.200,P=0.005)。瞳孔扩大≥6.0mm组主观畏光感为2~3级者12眼,瞳孔扩大4.5~5.5mm组者仅2眼,差异有统计学意义(H=19.840,P=0.000)。瞳孔扩大≥6.0mm组术中虹膜出血者7眼,明显高于瞳孑L扩大4.5~5.5mm组的3眼,差异有统计学意义(x2=5.290,P=0.030)。术后3个月2个组患眼的视力均有不同程度的提高。结论陈旧性葡萄膜炎瞳孔闭锁并发性白内障患眼手术中可采用均匀松解、扩张瞳孔的方法,瞳孔扩张直径不超过5.5mm时可获得满意的近似生理性瞳孔,提高患者的视觉质量。 展开更多
关键词 瞳孔闭锁 并发性白内障 瞳孔直径 葡萄膜炎
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超声乳化人工晶状体植入治疗葡萄膜炎并发性白内障 被引量:14
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作者 朱江 孙红艳 +1 位作者 吴艳 黄振平 《国际眼科杂志》 CAS 2016年第10期1933-1936,共4页
目的:探讨白内障超声乳化联合人工晶状体植入手术治疗葡萄膜炎并发性白内障的手术疗效。方法:本研究采用系统性回顾研究,选取2015-01/12在南京军区南京总医院眼科诊断为葡萄膜炎并发性白内障的患者57例57眼,所有患者均行白内障超声乳化... 目的:探讨白内障超声乳化联合人工晶状体植入手术治疗葡萄膜炎并发性白内障的手术疗效。方法:本研究采用系统性回顾研究,选取2015-01/12在南京军区南京总医院眼科诊断为葡萄膜炎并发性白内障的患者57例57眼,所有患者均行白内障超声乳化联合人工晶状体植入术,对患者的术中并发症,术后效果及并发症情况进行回顾分析。对手术前后视力进行非参数Wilcoxon检验。结果:所选患者超声乳化术中发生虹膜出血21眼(37%),后囊膜破裂4眼(7%),人工晶状体无法植入4眼(7%),术后裸眼视力获得不同程度提高,术前裸眼视力≥0.1者8眼(14%),术后3mo裸眼视力≥0.1者42眼(74%),差异有统计学意义(Z=23.42,P<0.001)。术后1d发生角膜水肿17眼(30%)、葡萄膜炎2眼(4%)、高眼压1眼(2%),术后1wk发生角膜水肿3眼(5%),术后1mo发生葡萄膜炎1眼(2%),术后3mo发生角膜水肿1眼(2%)、葡萄膜炎2眼(4%)、高眼压1眼(2%)、后发性白内障3眼(5%)。结论:白内障超声乳化联合人工晶状体植入手术治疗葡萄膜炎并发性白内障,术后效果好,并发症少。 展开更多
关键词 葡萄膜炎 白内障 裸眼视力 超声乳化
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葡萄膜炎并发性白内障31例的手术治疗 被引量:12
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作者 黄瑞华 王梅芳 +1 位作者 汪金方 郁文国 《国际眼科杂志》 CAS 2005年第3期555-557,共3页
目的:探讨葡萄膜炎并发性白内障虹膜后粘连小瞳孔状态下手术技巧、时机及疗效。方法:对葡萄膜炎并发性白内障小瞳孔患者31例35眼,在葡萄膜炎控制稳定,炎症消退3mo后,借助粘弹剂分离虹膜后粘连或施行虹膜环形切除,再行白内障超声乳化或... 目的:探讨葡萄膜炎并发性白内障虹膜后粘连小瞳孔状态下手术技巧、时机及疗效。方法:对葡萄膜炎并发性白内障小瞳孔患者31例35眼,在葡萄膜炎控制稳定,炎症消退3mo后,借助粘弹剂分离虹膜后粘连或施行虹膜环形切除,再行白内障超声乳化或囊外摘出及人工晶状体植入。结果:术后32眼(91%)视力较术前提高,其中≥0.5者13眼,0.3~0.5者12眼,0.1~03者7眼。瞳孔圆形或椭圆形。术后眼压均控制在正常范围。结论:葡萄膜炎并发性白内障虹膜后粘连,可使瞳孔扩大成圆形或椭圆型,有利于实施白内障超声乳化或囊外摘除,且瞳孔括约肌不受损伤,避免术后眩光,可获得良好视力,术中术后并发症减少。 展开更多
关键词 葡萄膜炎 并发症 白内障 瞳孔
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葡萄膜炎并发白内障的手术效果分析 被引量:21
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作者 叶纹 冯佩丽 《眼科新进展》 CAS 2001年第3期197-198,共2页
目的分析葡萄膜炎并发性白内障的手术效果。方法对 2 9例 31眼葡萄膜炎并发性白内障患者施行超声乳化白内障摘出术。其中虹膜睫状体炎 14眼 ,Fuchs异色性虹膜睫状体炎 7眼 ,中间葡萄膜炎 7眼 ,Vogt-小柳 -原田综合征 2眼 ,交感性眼炎 1... 目的分析葡萄膜炎并发性白内障的手术效果。方法对 2 9例 31眼葡萄膜炎并发性白内障患者施行超声乳化白内障摘出术。其中虹膜睫状体炎 14眼 ,Fuchs异色性虹膜睫状体炎 7眼 ,中间葡萄膜炎 7眼 ,Vogt-小柳 -原田综合征 2眼 ,交感性眼炎 1眼。随访 5~ 2 8mo,平均 15 mo,并进行回顾性分析。结果术后矫正视力≥ 0 .5者占 80 % ,1眼(Vogt-小柳 -原田综合征 )术后出现较严重的前部葡萄膜炎症 ,1眼 (虹膜睫状体炎 )见 IOL表面纤维素性渗出膜 ,2眼(中间葡萄膜炎 ) IOL表面见片状白色碎屑。结论采用对眼组织损伤较小的超声乳化技术 ,术中避免刺激虹膜 ,尽量清除晶状体皮质 ,并将 IOL 植入囊袋内 ,对于在炎症相对静止期的葡萄膜炎 ,同样可获得较轻的术后炎症反应、较少的并发症和较好的视力。 展开更多
关键词 白内障 葡萄膜炎 超声乳化术 并发症
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人工晶状体植入术后迟发性葡萄膜炎发病机制探讨 被引量:10
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作者 张建华 盖秀花 +2 位作者 许国强 杜耀武 刘卫华 《眼外伤职业眼病杂志》 北大核心 2003年第6期365-366,共2页
目的 观察后房人工晶状体植入术后循环免疫复合物的变化过程,探讨迟发性急性葡萄膜炎的发病机制。方法 成年大耳白兔20只,完成右眼透明晶状体乳化吸出囊袋内人工晶状体植入术,分别在术前及术后不同时间采耳静脉血,用聚乙二醇比浊法测定... 目的 观察后房人工晶状体植入术后循环免疫复合物的变化过程,探讨迟发性急性葡萄膜炎的发病机制。方法 成年大耳白兔20只,完成右眼透明晶状体乳化吸出囊袋内人工晶状体植入术,分别在术前及术后不同时间采耳静脉血,用聚乙二醇比浊法测定循环免疫复合物;并在裂隙灯下观察眼内炎症反应情况。结果 术后循环免疫复合物显著升高(t′=15.07,P<0.01),并在术后2~4周内维持较高水平。早期服内炎症反应在术后2周内基本消失。结论 后房人工晶状体植入术后迟发性急性葡萄膜炎是由免疫复合物介导的急性葡萄膜炎症反应。 展开更多
关键词 人工晶状体植入术 术后 迟发性葡萄膜炎 发病机制 循环免疫复合物 白内障
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超声乳化吸除治疗葡萄膜炎并发白内障的研究 被引量:4
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作者 赵保文 代海燕 +1 位作者 郝琳娜 朴天华 《国际眼科杂志》 CAS 2012年第3期542-543,共2页
目的:探讨施行超声乳化吸除人工晶状体植入治疗葡萄膜炎并发白内障的疗效。方法:回顾分析32例38眼葡萄膜炎并发白内障患者超声乳化手术治疗前后的情况。手术中先用黏弹剂钝性分离,瞳孔不能扩大者,用囊内剪沿瞳孔缘做环形剪除,做连续环... 目的:探讨施行超声乳化吸除人工晶状体植入治疗葡萄膜炎并发白内障的疗效。方法:回顾分析32例38眼葡萄膜炎并发白内障患者超声乳化手术治疗前后的情况。手术中先用黏弹剂钝性分离,瞳孔不能扩大者,用囊内剪沿瞳孔缘做环形剪除,做连续环形撕囊,囊袋内植入人工晶状体,观察手术并发症和术后视力,观察时间为术后6mo。结果:术后1mo有33眼(87%)视力较术前提高,其中>0.5者22眼,0.3~0.5者6眼,0.1~0.25者7眼,<0.1者3眼,术后瞳孔接近圆形。部分瞳孔恢复对光反应,无严重并发症发生。结论:本手术方法对葡萄膜炎并发白内障有良好的疗效,手术损伤小。 展开更多
关键词 超声乳化吸除 并发性白内障 葡萄膜炎
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