Development and validation of a risk prediction model for repeated indwelling urinary catheterization in patients with cervical cancer after surgery

Objective:To study the factors influencing secondary indwelling catheterisation after cervical cancer surgery and to develop a predictive risk model.Methods:A total of 260 patients in a tertiary hospital in Chongqing were selected from January 2020 to December 2021 via convenience sampling.Relevant information of patients was recorded,including age;body mass index;history of hypertension and diabetes,bladder dysfunction,postoperative urinary retention,and postoperative urinary tract infection;Histology;staging;surgical approach;Operation time;Time of first remove of catheter;indwelling catheter days;Hospitalization days.Least absolute shrinkage and selection operator was used to reduce dimensionality and select patient characteristics,and multivariate analysis was performed based on the selected variables.Based on the outcome of analysis,a line chart model was developed for predicting the risk of secondary catheterization in patients with indwelling catheterization after radical cervical cancer surgery.The coefficient of conformity index(C-index)and calibration curves were used to evaluate the accuracy and fit.The model was internally validated via bootstrapping(1000 random samples),and the clinical utility of the model was assessed via decision curve analysis(DCA).Results:Four characteristic variables were selected,including preoperative bladder function,postoperative urinary tract infection,surgical approach,and Time of first remove of catheter.They are independent risk factors affecting urinary tract.The risk prediction model exhibited good discrimination performance with a C-index of 0.722(95%CI,0.661-0.783)and was well calibrated.The C-index was 0.708 in internal validation analysis.DCA showed that the risk model was clinically useful for predicting secondary catheterization,and clinical benefits were observed at the decision threshold of≥11%.Conclusion:A novel model was developed to predict the risk of secondary catheterization.The model was based on preoperative bladder dysfunction,postoperative urinary tract infection,surgical approach,and number of days since the removal of the primary catheter.

Indwelling catheter and conservative measures in the treatment of abdominal compartment syndrome in fulminant acute pancreatitis

AIM： To study the effect of combined indwelling catheter, hemofiltration, respiration support and traditional Chinese medicine （e.g. Dahuang） in treating abdominal compartment syndrome of fulminant acute pancreatitis. METHODS： Patients with fulminant acute pancreatitis were divided randomly into 2 groups of combined indwelling catheter celiac drainage and intra-abdominal pressure monitoring and routine conservative measures group （group 1） and control group （group 2）. Routine non-operative conservative treatments including hemofiltration, respiration support, gastrointestinal TCM ablution were also applied in control group patients. Effectiveness of the two groups was observed, and APACHE Ⅱ scores were applied for analysis. RESULTS： On the second and fifth days after treatment, APACHE Ⅱ scores of group 1 and 2 patients were significantly different. Comparison of effectiveness （abdominalgia and burbulence relief time, hospitalization time） between groups 1 and 2 showed significant difference, as well as incidence rates of cysts formation. Mortality rates of groups 1 and 2 were 10.0% and 20.7%, respectively. For patients in group 1, celiac drainage quantity and intra-abdominal pressure, and hospitalization time were positively correlated （r = 0.552, 0.748, 0.923, P 〈 0.01） with APACHE Ⅱ scores. CONCLUSION： Combined indwelling catheter celiac drainage and intra-abdominal pressure monitoring, short veno-venous hemofiltration （SVVH）, gastrointestinal TCM ablution, respiration support have preventive and treatment effects on abdominal compartment syndrome of fulminant acute pancreatitis.

Management of recurrent malignant pleural effusions with a tunneled indwelling pleural catheter

In this review, we report on the use of indwelling pleural catheters in the treatment of malignant pleural effusions. We describe the most commonly used catheter. Also, treatment with indwelling pleuralcatheters as compared to talc pleurodesis is reviewed. A comparison of efficacy, costs, effects on quality of life, and complications is made. Only one randomized controlled trial comparing the two is available up to date, but several are underway. We conclude that treatment for malignant pleural effusions with indwelling pleural catheters is a save, cost-effective, and patientfriendly method, with low complication rates.

Indwelling Pleural Catheter Insertion Following Inefficient Thoracoscopic Decortication in Postpneumonic Empyema: Beneficial or Contraindicated?

Video assisted thoracic surgery in advanced stage postpneumonic empyema aims for thorough debridement and washout of the pleural space followed by an attempt to release the entrapped lung (decortication). When the latter isn’t successful, and the patient is in a poor performance status, applying tube thoracostomy is the usual routine, to avoid conversion to thoracotomy and open decortication. Tube thoracostomy, however, is associated with complications necessitating further surgery, needs long term follow up and also entails quality of life distorting issues. To overcome these disadvantages, we instead inserted a PleurX&reg indwelling pleural catheter in four patients in the above situation. The method brought success (lung re-expansion and complete or partial pleurodesis) without the need for further surgery or quality of life problems in either patient. Although the use of the indwelling pleural catheter in infected pleural space is not recommended by manufacturers, we noted no complications.

Effect of Cluster Nursing in Preventing Urinary Tract Infection in Postoperative Patients with Indwelling Urinary Catheter

Objective:This paper expounds and analyzes the effect of cluster nursing in preventing urinary tract infection in postoperative patients with indwelling urinary catheter.Methods:A total of 400 postoperative patients with indwelling urinary catheter,treated in Yancheng No.1 People’s Hospital in recent two years,were recruited as research subjects.The patients were equally divided into group A and group B,with 200 patients in each group,and all received routine anti-infectives.The patients in group A(200 cases)received routine nursing.On the basis of group A,cluster nursing was implemented for patients in group B(200 cases).Results:The indwelling time of urinary catheter,the disappearance time of bladder irritation symptoms,and the probability of urinary tract infection were compared between both groups,which showed that the nursing effect of group B was better than that of group A(P<0.05).Conclusion:The implementation of cluster nursing in postoperative patients with indwelling urinary catheter can improve the deficiency of routine nursing,consolidate the treatment effect,and reduce the complication rate of urinary tract infection.

Effect of modified puncture method on catheter-related bloodstream infection after PICC catheterization in patients with tumor

Objective: To explore the preventive effect of modified puncture method on catheter-related bloodstream infection after PICC catheterization in patients with tumor. Methods: A total of 95 cases of tumor admitted to our hospital from February 2015 to February 2017 were selected according to the order of admission, divided into the study group (n=47) and the control group (n=48). In the control group, the traditional blind catheterization was carried out, and the research group improved the puncture method. The rate of puncture success (onetime puncture success rate, total success rate), puncture time and complication rate were compared between the two groups. Results: The total success rate (77.1%) of the study group (97.9%) was significantly higher than control group, The puncture time of the study group was significantly shorter than control group. Incidence of complications in the study group (4.3%) was significantly lower than that in the control group (22.9%). Conclusions: The improved puncture method can significantly reduce the incidence of complications after PICC catheterization, shorten the puncture time and improve the success rate of puncture, which is worthy of reference and promotion.

Clinical analysis of central venous catheter-related infections in patients in the emergency ICU

BACKGROUND:Catheter-related infection(CRI)of the central vein is a common cause of nosocomial infection.This study was undertaken to investigate the pathogen culturing and risk factors of CRI in emergency intensive care unit(EICU)in order to provide the beneficial reference.METHODS:From January 2008 to December 2010,a total of 1 363 patients were subjected to catheterization.In these patients,the peak CRI rate of the patients was determined by bacterial cultivation and blood bacterial cultivation.RESULTS:CRI happened in 147 of the 1 363 patients using the central venous catheter.The peak rate of CRI was 10.79%,with an incidence of 3.05 episodes per 1 000 catheter days.Of the147 patients,46.94%had gram-negative bacilli,40.14%had gram-positive cocci,and 12.92%had fungi.Unconditional logistic regression analysis suggests that multiple catheterization,femoral vein catheterization,the application of multicavity catheter,and the duration of catheterization were the independent risk factors for CRI.CONCLUSION:The risk factors for catheter-related infections should be controlled to prevent the occurrence of nosocomial infection.

Effectiveness and Safety of Double-balloon Catheter versus Intra-amniotic Injection of Ethacridine Lactate for Termination of Second Trimester Pregnancy in Patients with Liver Dysfunction

Severe liver dysfunction in pregnancy（SLDP） is rare but serious complications with high mortality rate. This study compared the effectiveness and safety of double-balloon catheter versus intra-amniotic injection of ethacridine lactate for the termination of second trimester pregnancy in patients with SLD. A total of 55 patients with indications of labor induction were enrolled and analyzed by retrospective control analysis method. Twenty-three cases adopted Cook double balloon dilation as Cook group, and 32 cases received intra-amniotic injection of ethacridine lactate as EL group. The primary outcome was evaluated by successful abortion rate and the difference in the induction-to-abortion interval. Secondary outcomes included liver function recovery and the frequency of adverse events. Both Cook and EL regimens were effective, with successful abortion rate of 87.0% and 93.8%, respectively（P=0.639）. The induction-to-delivery interval was similar between Cook group and EL group（38.1±21.5 vs. 41.3±17.4, P=0.543）. The liver disease status was more severe in Cook group than in EL group, but it did not show any significant difference after pregnancy termination between the two groups and the improvement rate also did not show any significant difference. Both treatments were safe and there was no significant difference in bleeding and cervical laceration adverse events between the two groups. Our study firstly compared double-balloon catheter and ethacridine lactate for the induction of labor in women with SLD during second trimester pregnancy.

Clinical Study on the Treatment of 325 Cases of Atrioventricular Node Reentrant Tachycardia by Radiofrequency Catheter Ablation

In order to improve the efficacy of modified inferior method or middle method of radiofrequency catheter ablation (RFCA) in the treatment of atrioventricular node reentrant tachycardia (AVNRT), the clinical data of 325 cases of AVNRT from March 1992 to Feb. 2000 being subjected to the treatment of RFCA were retrospectively analyzed. The results showed that the successful rate was increased and recurrence was decreased year by year. In the recent 4 years the effective rate was up to 100 %. The complication of three grade of AVB occurred in 3 % and recurrent rate in 9.1 % before March 1996, but both of them were zero in the last 3 years. The time of RFCA procedure and X ray exposure was significantly reduced. It was concluded that ablating more than 3 targets by modified inferior method or middle method with energy titrating and strict endpoint was the crux of obtaining satisfactory therapeutic effects and preventing recurrence.

Inadvertent placement of a urinary catheter into the ureter: A report of 3 cases and review of the literature

We describe three cases of inadvertent placement of the urinary catheter into the ureter.An 85-year-old gentleman on long-term indwelling catheter(IDC)for neurogenic bladder presented with fever and right flank pain.CT of abdomen and pelvis demonstrated the tip of the IDC to be located within the right vesicoureteric junction with acute right hydronephrosis and acute pyelonephritis.A 74-year-old woman,on long-term IDC for neurogenic bladder was found to have hydronephrosis on ultrasound imaging.Contrast-enhanced CT intravenous pyelography done subsequently showed the IDC was in the right distal ureter.A 47-year-old lady,on IDC for urinary retention and voiding dysfunction likely secondary to schizophrenia and anti-psychotic medications,presented with raised creatinine.A non-enhanced CT of her abdomen and pelvis was done and showed that the tip of the urethral IDC was located up to the left vesicoureteric junction.In all patients,the hydronephrosis resolved after changing the catheter and they were well on discharge.We also review the literature to identify the incidence,outcomes and possible risk factors.To our knowledge,only 20 cases have been reported thus far in the English literature.Although serious complications can occur,the incidence is very low.One risk factor that has been identified is long-term catheterization in patients with neurogenic bladder.We do not recommend routine imaging after catheterization in this group of patients.However,we should still be mindful of the possibility of this occurrence and evaluate and treat as necessary when clinical suspicion arises.

Application of Midline Catheter in Patients with Oral Cavity Malignancies during Perioperative Period

Objective: The study aims to compare the application value of midline catheter and indwelling needle in patients with oral cavity malignancies during perioperative period. Methods: 146 patients with oral cavity malignancies admitted to our hospital from January 2019 to July 2021 were selected as the research subjects. 73 patients treated with midline catheters during the treatment were the experimental group, and another 73 patients were treated with indwelling needles as the control group. The indwelling time, total number of puncturing times, and incidence of adverse reactions of two catheterization methods were compared between the two groups. Meanwhile, each patient was investigated for treatment satisfaction. Result: The indwelling time was significantly longer in the experimental group than in the control group (P < 0.0001), and the total number of puncturing times in the experimental group was significantly lower than that in the control group (P < 0.0001). The incidence of adverse reactions in the experimental group (χ2 = 4.960, P = 0.0259) was significantly lower than that in the control group in terms of catheter occlusion (χ2 = 12.56, P = 0.0004), catheter detachment (χ2 = 8.46, P = 0.0036), drug extravasation (χ2 = 3.27, P = 0.0011), phlebitis (χ2 = 3.62, P = 0.0003), and bleeding from the puncture point (χ2 = 14.98, P = 0.0001). The satisfaction rate (χ2 = 33.45, P < 0.0001) and fundamental satisfaction rate (χ2 = 16.57, P < 0.0001) in the experimental group were significantly higher than those in the control group, while the dissatisfaction rate was significantly lower than that in the control group (χ2 = 11.38, P = 0.0007). The difference is statistically significant. Conclusion: Compared with indwelling needle, the application of midline catheters in patients with oral cavity malignancies during perioperative period can effectively reduce the number of puncturing times and the incidence of catheter-related adverse reactions, with a high satisfaction rate, which is worthy of clinical promotion and application.

The Application of Midline Catheter in Perioperative Period of Patients with Laryngopharyngeal Cancer

Objective: To investigate the application value of midline catheters in patients with larynx cancer during the postoperative period. Methods: 150 patients with larynx cancer treated in our hospital from May 2019 to May 2022 were selected as the study objects. According to the random number method, 75 cases were divided into a control group and a study group. The study group used a midline catheter during treatment, and the control group used a Peripheral venous indwelling needle during treatment. The indwelling time, puncture times, complication rate, daily catheter maintenance cost and catheterization satisfaction rate of the two groups were compared. Result: The retention time of the study group (11.53 ± 6.91 days) was significantly higher than that of the control group (2.92 ± 1.41 days) (P . The total puncture times were significantly lower than that of the control group (P cidence of complications such as catheter blockage, catheter detachment, drug extravasation and phlebitis were lower than those of the control group. The difference was statistically significant (P < 0.05), the average daily maintenance cost of the two groups was not statistically significant (P > 0.05), and the satisfaction rate of the study group was significantly higher than that of the control group, the difference was statistically significant (P Conclusion: Compared with the Peripheral venous indwelling needle, postoperative application of a midline catheter in patients with larynx cancer can effectively reduce the number of puncture times and the incidence of catheter-related adverse reactions, and has higher economic benefits and satisfaction rate, which is worthy of clinical application.

New cannulation method for pancreatic duct cannulationbile duct guidewire-indwelling method

The patient was a 58-year-old male with symptomatic alcoholic chronic pancreatitis.Since a 10 mm calculus was observed in the pancreatic body and abdominal pain occurred due to congestion of pancreatic juice,endoscopic retrograde cholangiopancreatography was conducted for assessment of the pancreatic duct and treatment of pancreatic calculus.Pancreatogram was slightly and insuff iciently obtained by injecting the contrast media via the common channel of the duodenal main papilla.We tried to cannulate selectively into the pancreatic duct for a clear image.However,the selective cannulation of the pancreatic duct was difficult because of instability of the papilla.On the other hand,selective cannulation of the bile duct was relatively easily achieved.Therefore,after the imaging of the bile duct,a guidewire was retained in the bile duct to immobilize the duodenal papilla and cannulation of the pancreatic duct was attempted.As a result,selective pancreatic duct cannulation became possible.It is considered that the bile duct guidewire-indwelling method may serve as one of the useful techniques for cases whose selective pancreatic duct cannulation is diff icult("selective pancreatic duct diff icult cannulation case").

Palliative long-term abdominal drains vs large volume paracenteses for the management of refractory ascites in end-stage liver disease

BACKGROUND Long-term abdominal drains(LTAD)are a cost-effective palliative measure to manage malignant ascites in the community,but their use in patients with end-stage chronic liver disease and refractory ascites is not routine practice.The safety and cost-effectiveness of LTAD are currently being studied in this setting,with preliminary positive results.We hypothesised that palliative LTAD are as effective and safe as repeat palliative large volume paracentesis(LVP)in patients with cirrhosis and refractory ascites and may offer advantages in patients’quality of life.AIM To compare the effectiveness and safety of palliative LTAD and LVP in refractory ascites secondary to end-stage chronic liver disease.METHODS A retrospective,observational cohort study comparing the effectiveness and safety outcomes of palliative LTAD and regular palliative LVP as a treatment for refractory ascites in consecutive patients with end-stage chronic liver disease followed-up at our United Kingdom tertiary centre between 2018 and 2022 was conducted.Fisher’s exact tests and the Mann-Whitney U test were used to compare qualitative and quantitative variables,respectively.Kaplan-Meier survival estimates were generated to stratify time-related outcomes according to the type of drain.RESULTS Thirty patients had a total of 35 indwelling abdominal drains and nineteen patients underwent regular LVP.The baseline characteristics were similar between the groups.Prophylactic antibiotics were more frequently prescribed in patients with LTAD(P=0.012),while the incidence of peritonitis did not differ between the two groups(P=0.46).The incidence of acute kidney injury(P=0.014)and ascites/drain-related hospital admissions(P=0.004)were significantly higher in the LVP group.The overall survival was similar in the two groups(log-rank P=0.26),but the endpoint-free survival was significantly shorter in the LVP group(P=0.003,P<0.001,P=0.018 for first ascites/drain-related admission,acute kidney injury and drain-related complications,respectively).CONCLUSION The use of LTAD in the management of refractory ascites in palliated end-stage liver disease is effective,safe,and may reduce hospital admissions and utilisation of healthcare resources compared to LVP.

心房颤动导管消融围手术期患者体验测量工具的初步构建

目的初步构建心房颤动(atrial fibrillation,AF)导管消融围手术期患者体验测量工具,为改善患者围手术期体验提供可量化的依据。方法于2022年6月至2023年4月采用文献分析、质性研究、德尔菲专家咨询及层次分析法,确定房颤导管消融围手术期患者体验测量问卷的内容及各测量内容的权重。结果3轮专家的积极性均为100%,专家的权威系数分别为0.946、0.961、0.976,第2、3轮专家咨询的肯德尔协调系数为0.130、0.370(P<0.001)。初步构建的AF导管消融围手术期患者体验测量工具包含操作及技术质量体验、舒适度管理体验、信息与沟通交流体验、情感支持体验、服务流程与响应体验5个维度,共46个测量条目。结论根据专科特点初步构建的AF导管消融围手术期患者体验测量工具,不仅可以精准化评估患者体验现状,而且可以为有针对性地开展相关改进医疗机构服务质量提供依据。

仅用生理盐水冲封管在三向瓣膜式中长导管留置输液中的应用效果

目的:探讨仅用生理盐水冲封管在三向瓣膜式中长导管留置输液中的应用效果。方法:回顾性分析2021年3月至2022年2月在该院行静脉留置导管输液治疗的160例肺结核病患者的临床资料,根据封管方式不同将其分为对照组和观察组各80例。两组均留置三向瓣膜式中长导管输液7周左右,对照组采用生理盐水脉冲式冲管联合100 U/mL肝素溶液正压封管,观察组仅用生理盐水冲封管。比较两组导管留置时间、住院时间、单次封管费用、封管平均用时、不良事件发生率及护理满意度。结果:观察组导管留置时间长于对照组,住院时间短于对照组,差异均有统计学意义(P<0.05);观察组单次封管费用少于对照组,封管平均用时短于对照组,差异均有统计学意义(P<0.05);两组导管堵塞、血流感染、静脉炎发生率比较,差异均无统计学意义(P>0.05);观察组护理满意度为96.25%(77/80),高于对照组81.25%(65/80),差异有统计学意义(P<0.05)。结论:仅用生理盐水冲封管用于三向瓣膜式中长导管留置输液患者能有效延长导管留置时间,缩短封管平均用时和住院时间,降低封管费用,提高护理满意度,且不增加导管堵塞、血流感染、静脉炎的发生率,效果优于生理盐水冲管联合肝素溶液封管。

转头前倾法在脑卒中吞咽功能障碍患者留置胃管中的效果观察

目的研究转头前倾法在脑卒中吞咽功能障碍患者留置胃管中的作用。方法临床纳入2022年1月至2023年2月期间我院收治的84例脑卒中吞咽功能障碍患者作为研究对象,将患者分为两组各42例(随机数字表法),所有患者均需留置胃管。其中42例患者采用常规方法进行留置胃管作为对照组;另42例患者采用转头前倾法进行留置胃管作为观察组。观察两组患者置管成功率、不良反应发生率、生活质量以及护理人员对吞咽功能障碍摄食训练相关知识的知晓率情况。结果观察组一次置管成功率和再次置管成功率分别为92.86%、100.00%,均高于对照组的76.19%、30.00%,均有差异(P<0.05)。观察组不良反应发生率明显低于对照组的不良反应发生率(4.76%vs 19.05%),有差异(P<0.05)。干预前两组患者生活质量各评分对比无差异(P>0.05);干预后观察组生活质量各评分均优于对照组,均有差异(P<0.05)。培训后护理人员对吞咽功能障碍摄食训练相关知识的知晓率为96.67%,明显高于培训前的53.33%,有差异(P<0.05)。结论转头前倾法能使护理人员更好掌握吞咽功能障碍摄食训练的相关知识,有效提高脑卒中吞咽功能障碍患者留置胃管的成功率,降低不良反应发生率,进一步提高患者生活质量,值得临床应用及推广。

成人中心静脉导管堵塞处置及预防的证据总结

目的检索、评价并总结成人中心静脉导管(central venous catheter,CVC)堵塞处置及预防措施的相关循证证据,为临床护理实践提供循证依据。方法计算机检索2012年1月—2023年7月共19个中英文文献数据库、临床指南数据库及相关协会网站中关于成人CVC管理、堵塞预防及处置的所有证据,包括指南、专家共识、证据总结、证据实践、系统评价和Meta分析。采用临床指南研究与评价系统Ⅱ(appraisal of guidelines for research and evaluationⅡ,AGREEⅡ)、系统综述评价工具2(a measurement tool to assess systematic reviews 2,AMSTAR 2)及澳大利亚循证卫生保健中心专家意见与专家共识质量评价工具(joanna briggs institute text and expert opinion critical appraisal tool,JBI TEOCAT)进行文献质量评定,采用澳大利亚循证卫生保健中心(joanna briggs institute,JBI)证据分级和推荐系统进行证据质量评定。结果初步检索共获得文献891篇,最终纳入文献15篇,汇总了26条最佳证据。结论CVC的堵塞可从导管的全生命周期和全程管理入手进行有效预防,堵塞发生后应根据堵塞性质尽快处理。临床护士可以应用证据总结,结合实际情况制定护理策略进行CVC管理,降低CVC堵塞发生率。

早产儿PICC置管改良版体外预测量技术的应用与研究

目的 探讨改良版体外预测量方法应用在早产儿经外周置入中心静脉导管(PICC)置管中的可行性。方法选取2018年12月1日至2022年8月31日在首都儿科研究所附属儿童医院行PICC治疗的早产儿95例作为研究对象,按随机数字表法分为对照组47例(采用标准的体外预测量方法 )和试验组48例(采用改良版体外预测量方法 ),比较2组PICC尖端一次性到位率、导管置入长度和留置时间。结果 试验组PICC尖端一次到位率为87.5%,显著优于对照组的59.57%,差异有统计学意义(P <0.05)。试验组与对照组在导管置入长度和留置时间方面差异无统计学意义(P> 0.05)。结论 改良版体外预测量方法与理想置管深度更符合,出现偏差率低,且测量更简便,易操作。

成人外周静脉留置针导管失效风险列线图预测模型的构建

目的识别成人外周静脉留置针导管失效的风险因素,建立成人外周静脉留置针导管失效风险预测模型并检验其预测效果。方法采用便利抽样法选取2021年3-4月某省6家医院的1022例置入外周静脉留置针的患者作为研究对象,根据是否发生导管失效分为非导管失效组(n=336)和导管失效组(n=686)。采用logistic回归分析构建预测模型,采用Bootstrap重抽样法进行内部验证,用受试者工作特征曲线下面积(ROC)和霍斯默-莱梅肖(H-L)拟合优度检验评价模型的预测效果。结果成人外周静脉留置针导管失效的独立风险因素包括通过院内培训获得外周静脉导管维护资质的护士、外科住院患者、健康教育依从性差的患者、穿刺侧肢体活动受限的患者、使用>20 G留置针、使用开放型留置针、患者主诉异常、输注刺激性药物、日输液总量≥1500 mL。风险预测模型ROC曲线下面积为0.731[95%CI(0.700~0.762)]。内部验证后C指数为0.722[95%CI(0.691,0.753)],H-L检验结果显示,χ^(2)=3.414(P=0.755)。结论本研究构建风险预测模型具有良好的预测效能,能为临床早期甄别外周静脉留置针导管失效的高危人群提供参考。