An effective approach for the construction of the decalin ring skeleton of labdane diterpenoids was developed based on a key biomimetic cationic polyene cyclization of an epoxy allylsilane precursor. The synthetic a...An effective approach for the construction of the decalin ring skeleton of labdane diterpenoids was developed based on a key biomimetic cationic polyene cyclization of an epoxy allylsilane precursor. The synthetic approach demonstrated here would be useful in the enantioselective and diastereoselective total synthesis of natural labdane diterpenoids in general.展开更多
A highly efficient and convergent approach for the synthesis of octalone 1, the focal intermediate for the synthesis of several sesquiterpenoids, was developed based on the cationic cyclization strategy of the functio...A highly efficient and convergent approach for the synthesis of octalone 1, the focal intermediate for the synthesis of several sesquiterpenoids, was developed based on the cationic cyclization strategy of the functionalized oxabicyclic template 5.展开更多
An enhancive synthesis of (±)-1β, 11-diol-4-en-eudesmol, starting from 2-chloroacrylonitrile, is described. The effect of temperature on the Diels-Alder reaction of 2-chloroacrylonitrile with 2-methylfuran and t...An enhancive synthesis of (±)-1β, 11-diol-4-en-eudesmol, starting from 2-chloroacrylonitrile, is described. The effect of temperature on the Diels-Alder reaction of 2-chloroacrylonitrile with 2-methylfuran and the condition of cationic cyclization of diene were discussed in detail.展开更多
基金financial support from the National Outstanding Youth Fund(No.29925204)
文摘An effective approach for the construction of the decalin ring skeleton of labdane diterpenoids was developed based on a key biomimetic cationic polyene cyclization of an epoxy allylsilane precursor. The synthetic approach demonstrated here would be useful in the enantioselective and diastereoselective total synthesis of natural labdane diterpenoids in general.
基金Supported by the National Natural Science Foundation of China(No20272021)
文摘A highly efficient and convergent approach for the synthesis of octalone 1, the focal intermediate for the synthesis of several sesquiterpenoids, was developed based on the cationic cyclization strategy of the functionalized oxabicyclic template 5.
基金Project supported by the National Natural Science Foundation of China(No.20272021).
文摘An enhancive synthesis of (±)-1β, 11-diol-4-en-eudesmol, starting from 2-chloroacrylonitrile, is described. The effect of temperature on the Diels-Alder reaction of 2-chloroacrylonitrile with 2-methylfuran and the condition of cationic cyclization of diene were discussed in detail.
