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Adverse Effects of Inactivated Foot-and-Mouth Disease Vaccine—Possible Causes Analysis and Countermeasures 被引量:1
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作者 Keshan Zhang Bingzhou Lu +3 位作者 Huanan Liu Junhao Zhao Haixue Zheng Xiangtao Liu 《World Journal of Vaccines》 2018年第4期81-88,共8页
Foot-and-mouth disease (FMD) is an infectious and sometimes fatal viral disease that affects cloven-hoofed animals, and Chinese government adopts compulsory immunization measures for FMD. The adverse effects of FMD va... Foot-and-mouth disease (FMD) is an infectious and sometimes fatal viral disease that affects cloven-hoofed animals, and Chinese government adopts compulsory immunization measures for FMD. The adverse effects of FMD vaccine to pigs, cattle and goats have been reported increasingly frequent during the spring and autumn seasons when large numbers of farm livestock are vaccinated. The financial losses caused by vaccine adverse effects have been a serious concern for both farmers and primary prevention personnel. There are various causative factors reported to involve into adverse effect of FMD vaccine, including the inappropriate vaccine production, transportation and storage, livestock poor tolerance, and unqualified vaccinating manipulations. Symptomatic treatment and early drug prevention have a certain effect on the adverse effects. To analyze causes and propose countermeasures, in the current study possible reasons during the production and processing procedures of inactivated FMD vaccine were reviewed and corresponding countermeasures were recommended. The review may provide references for better use of vaccine to prevent FMD. 展开更多
关键词 Foot-and-Mouth Disease INACTIVATED Vaccine ADVERSE effects causeS ANALYSIS and COUNTERMEASURES
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Giant Volume Magnetostriction Caused by Itinerant Electron Metamagnetic Transition and Pronounced Invar Effects in La(Fe_xSi_(1-x))_(13) Compounds 被引量:1
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作者 K.Fukamichi and A.Fujita (Department of Materials Science, Graduate School of Engineering, Tohoku University, Aoba-yama 02, Sendai 980-8579, Japan) 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2000年第2期167-171,共5页
A first-order itinerant electron metamagnetic (IEM) transition above the Curie temperature Tc for ferromagnetic La(Fe_xSi_1-x)13 compounds has been confirmed by applying magnetic field. The volume change just above T_... A first-order itinerant electron metamagnetic (IEM) transition above the Curie temperature Tc for ferromagnetic La(Fe_xSi_1-x)13 compounds has been confirmed by applying magnetic field. The volume change just above T_C for x=0.88 is huge of about 1.5%, which is caused by a large magnetic moment induced by the IEM transition. These compounds have a possibility for practical applications as giant magnetostrictive materials. Pronounced Invar effects bring about a negative thermal expansion below TC, closely correlated with the negative mode-mode coupling among spin fluctuations. 展开更多
关键词 COMPOUNDS Fe_xSi Giant Volume Magnetostriction caused by Itinerant Electron Metamagnetic Transition and Pronounced Invar effects in La
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THE PROTECTIVE EFFECT OF Na^+ CHANNEL BLOCKERS AGAINST CELL DAMAGE CAUSED BY ISCHEMIA 被引量:1
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作者 Zhu Zhongliang, Li Hui, Fan Xiaoli et al(Department of Physiology, Xi’an Medical University)$$$$ 《Journal of Pharmaceutical Analysis》 CAS 1999年第2期156-156,共1页
In order to observe it blockers of sodium channel obsesses the neuroprotective effect on hippocampal CA 1 pyramidal cell under the condition of transient brain ischemia, the present experiment used 24 male Wistar rat... In order to observe it blockers of sodium channel obsesses the neuroprotective effect on hippocampal CA 1 pyramidal cell under the condition of transient brain ischemia, the present experiment used 24 male Wistar rats aged 9 months and divided them into four groups. Lidocaine and/or furosemide were injected introcerebroventicularlly (I.C.V). Stained with H E and accounted the CA 1 pyramidal cell numbers by computer in each group suggested following findings: Although 5 μl of 2% lidocaine was injected I.C.V, the results indicated lidocaine didn't have any blockade to pyramidal cell injuries in hippocampal CA 1 area (P<0 05). In the group medicated with 2 5μl of both 2% lidocaine and 2% furosemide, the results showed that the combined approach had a blockade to injuries of pyramidal cells compared with control group (P<0 01). The present experiment indicates that the combined blockade of lidocaine and furosemide injected I.C.V. to Na + channel can prevent the injuries from hippocampal neurons owing to ischemia. 展开更多
关键词 THE PROTECTIVE effect OF Na AGAINST CELL DAMAGE causeD BY ISCHEMIA CHANNEL BLOCKERS
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A Cross-Sectional Study of the Causes, Effects and Management Strategies for Stress and Burnout among Nurses in the Fako Division, Cameroon
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作者 Acha Anwi Therese Ateh Stanislas Ketum +5 位作者 Mohamed Isah Thiery Pechap Ayafor Agbornkwai Nyenty Agbor Acha Therese Fomundam Anwi Malika Esembeson Nahyeni Bassah Esoh 《Journal of Biosciences and Medicines》 2020年第7期17-27,共11页
<strong>Introduction: </strong>Stress and burnout are a reality which nurses encounter and try to cope with especially in the Emergency Department (ED) so that they can provide optimal patient care. Nurses... <strong>Introduction: </strong>Stress and burnout are a reality which nurses encounter and try to cope with especially in the Emergency Department (ED) so that they can provide optimal patient care. Nurses who work in ED are front line providers of immediate medical care needed to stabilize patients. With the known critical shortage of health workforce in Cameroon, nurses are overloaded with work and often experience stress and burnout. <strong>Aim: </strong>This study aimed at determining the causes, effects and management strategies of stress and burnout among nurses working in the ED in hospitals in the Fako Division, Cameroon. <strong>Methods:</strong> This study was a descriptive cross-sectional study. The sample consisted of seventy nurses from five different hospitals. A purposive sampling technique was used and data was analyzed using SPSS version 16.0. Data was collected using a structured questionnaire developed from the International Stress Management Scale. <strong>Results: </strong>The highest reported cause of stress in this study was heavy workload (12.88%) and the least was no experience in handling the challenges of the department. The leading reported effect of stress was the development of musculoskeletal disorders such as joint and back pain (16.48%) and the least effect was contemplating quitting the profession (5.99%). The major management strategy used was humour (8.27%), while the least was crying out stress to feel relieved (2.18%).<strong> Conclusion: </strong>The major cause of stress and burnout among nurses in our study setting was heavy workload, which mostly results in joint and back pain. Moreover, humour was the prime management strategy for stress and burnout among nurses in the emergency department in the study setting. Thus more nurses should be employed and the working conditions of nurses improved to reduce the workload in the study hospitals. 展开更多
关键词 STRESS BURNOUT Nurses causeS effect and Management Cameroon
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THE FEED BACK INHIBITION EFFECT ON THEINFECTIOUS DEVELOPMENT CAUSED BY N'-ACYL-N-PHENYLHYDRAZINE
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作者 Ping CHEN Ren De SUN De Shui ZHENG Institute of Photographic Chemistry,Academia Sinica,Beijing 100101 《Chinese Chemical Letters》 SCIE CAS CSCD 1992年第1期5-8,共4页
The phenyl and methyl phenyl free radicals,formed in the oxidation-hydrolysis process of N’-acyl-N-phenylhydrazine, have been studied by ESR spectrometry.It was found that the free radical is the chief cause which pr... The phenyl and methyl phenyl free radicals,formed in the oxidation-hydrolysis process of N’-acyl-N-phenylhydrazine, have been studied by ESR spectrometry.It was found that the free radical is the chief cause which produces the feed-back inhibition effect in the hydrazine-promoted infectious development of silver halide. 展开更多
关键词 ESR ACYL-N-PHENYLHYDRAZINE THE FEED BACK INHIBITION effect ON THEINFECTIOUS DEVELOPMENT causeD BY N
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The effects of the environmental factors on Laminaria disease caused by alginic acid decomposing bacteria
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作者 Ding Meili Institute of Oceanology, Academia Sinica, Qingdao 266071, China 《Acta Oceanologica Sinica》 SCIE CAS CSCD 1992年第1期123-130,共8页
-The rot disease of Laminaria occurs often in nurseries of sporeling and commercial cultivation in the sea and results in economic loss greatly. Usually the disease outbreaks accompanied with massive multiplication of... -The rot disease of Laminaria occurs often in nurseries of sporeling and commercial cultivation in the sea and results in economic loss greatly. Usually the disease outbreaks accompanied with massive multiplication of alginic acid decomposing bacteria. From the section of the decaying Lamuutria which resulted from the inoculation of alginic acid decomposing bacteria, it was observed that the bacteria invaded the epiderm of the Laminaria surface at first, then entered the ex-odermis, endodermis and pith. In addition, there were a great amount of bacteria in the intercellular region and a lot of free cells of the algae in the decaying areas. The wall of some free cells was decomposed, which led to soft tissue or disintegration. Alginic acid decomposing bacteria are normal epiphytic microorganisms growing on Lamuutria surface. These bacteria do not cause disease at normal environmental conditions. The experiments showed that the unfavourable conditions, e. g. , wounding, overcrowding, high temperature reduced the ability of antibacterial activity and made the algae more susceptible to the pathogens and favoured the multiplication of alginic acid decomposing bacteria and finally led to the disease outbreak. The unfavourable environmental factors which resulted from a variety of reasons were the main cause of the disease. 展开更多
关键词 The effects of the environmental factors on Laminaria disease caused by alginic acid decomposing bacteria ACID
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Analysis of therapeutic effect of Tongkangning girdle on pain caused by hepatocarcinoma
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作者 王凯 王东盛 +1 位作者 徐玉梅 杨敏 《中国组织工程研究与临床康复》 CAS CSCD 2001年第18期147-,共1页
关键词 Analysis of therapeutic effect of Tongkangning girdle on pain caused by hepatocarcinoma
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Analysis of effects of radiotherapy on pain caused by metastic tumor of bone
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作者 张洪祥 陈法爱 张友平 《中国组织工程研究与临床康复》 CAS CSCD 2001年第24期152-,共1页
关键词 Analysis of effects of radiotherapy on pain caused by metastic tumor of bone
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Clinical study on the effect of abdominal cavity chemotherapy by hot perfusion and sustained low losmatic pressure on malignant ascites caused by gastrointestinal tumors
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作者 杨光 刘长安 《中国组织工程研究与临床康复》 CAS CSCD 2001年第18期152-,共2页
关键词 Clinical study on the effect of abdominal cavity chemotherapy by hot perfusion and sustained low losmatic pressure on malignant ascites caused by gastrointestinal tumors
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The environmental effect caused by the extraction of Karst groundwater in the city of Guiyang
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《Global Geology》 1998年第1期72-72,共1页
关键词 The environmental effect caused by the extraction of Karst groundwater in the city of Guiyang
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Because-因果句的语义概念化 被引量:1
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作者 董星华 《四川外语学院学报》 北大核心 2007年第5期100-105,共6页
一个because-因果句的语义概念化就是按照一般逻辑事理,根据言者的知识结构、相关的语境信息和具体的交际目的或意图,把两个事件或现象之间、两个主观认识之间、两个主观行为或这些事件、现象、认识、言语行为相互之间的联系概念化为因... 一个because-因果句的语义概念化就是按照一般逻辑事理,根据言者的知识结构、相关的语境信息和具体的交际目的或意图,把两个事件或现象之间、两个主观认识之间、两个主观行为或这些事件、现象、认识、言语行为相互之间的联系概念化为因果关系。一个because-因果句语义的概念化的方式具体有:象征概念化、推理概念化、语境选择概念化和跨域概念化。 展开更多
关键词 because一因果句 概念化 象征 推理 语境
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语篇建构的因果关系表征路径研究——以because小句关系的篇章构建为例
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作者 朱丽娟 杨玉晨 《延边大学学报(社会科学版)》 CSSCI 2020年第6期56-64,141,共10页
语篇建构可以通过不同的路径加以展开,而因果关系表征路径是最常用的方法之一。基于小句关系理论,对BNC语料库中高频因果关系because小句关系进行研究,可以清楚直观地体现出because小句关系表征路径对篇章宏观建构所起的统领和意义延伸... 语篇建构可以通过不同的路径加以展开,而因果关系表征路径是最常用的方法之一。基于小句关系理论,对BNC语料库中高频因果关系because小句关系进行研究,可以清楚直观地体现出because小句关系表征路径对篇章宏观建构所起的统领和意义延伸的作用,在微观层面上触发篇章建构特殊句式和词汇网络。因果关系表征路径对语篇建构产生影响,也为其他逻辑关系表征在篇章建构过程中的功能分析提供了新的视角,对语言教学与语言学习也具有重要的理论意义和实践意义。 展开更多
关键词 语篇建构 因果关系表征 小句关系 because小句
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Debates on the Causes of Global Warming 被引量:1
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作者 HUANG Jian-Bin WANG Shao-Wu +2 位作者 LUO Yong ZHAO Zong-Ci WEN Xin-Yu 《Advances in Climate Change Research》 SCIE 2012年第1期38-44,共7页
The controversy between the IPCC and Non-governmental IPCC(NIPCC) on the attribution of global warming are reviewed.IPCC holds that today's global warming is mainly due to anthropogenic activities rather than natu... The controversy between the IPCC and Non-governmental IPCC(NIPCC) on the attribution of global warming are reviewed.IPCC holds that today's global warming is mainly due to anthropogenic activities rather than natural variability,which is emphasized by NIPCC.The surface temperature observations since the mid-20th century support the hypothesis of anthropogenic impact,but for the last one hundred years or so,natural forcings such as solar activity, volcanic eruptions and thermohaline circulation variations also have had great influences on the Earth's climate,especially on inter-decadal timescales.In addition,evidence suggests that the Medieval Warm Period(MWP) and Little Ice Age (LIA) are closely associated with the solar activity over the past 1 thousand years.Over the past 10 thousand years, the North Atlantic cold events and solar activity are closely correlated.Nevertheless,the physical mechanisms of the solar-climate variability and interrelation are not well understood,yet.Notably,a prevailing view recently indicates that galactic cosmic rays may result in climatic cooling through modulating global low cloud cover.However,its process and mechanism need to be further investigated. 展开更多
关键词 全球变暖 原因 太阳活动 自然变异 物理机制 中世纪暖期 人类活动 人为影响
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Causes of Restocking Delays in Absence of Real Time Inventory Tracking of Airtel Airtime
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作者 Eddie Musana Annabella H. Basaza-Ejiri 《Journal of Data Analysis and Information Processing》 2020年第4期320-340,共21页
The <strong><em>purpose</em></strong> of this research was to ascertain causes of Restocking Delays in a Distributor Company of Airtel Airtime (<em>AA</em>) that give justification ... The <strong><em>purpose</em></strong> of this research was to ascertain causes of Restocking Delays in a Distributor Company of Airtel Airtime (<em>AA</em>) that give justification for benefits of using Real Time Inventory Tracking (<em>R.T.I.T</em>) in an attempt to mitigate Restocking Delays. From a study out at the Private Marketing and Trading Services (<em>PMTS</em>) an Authorized Distributor of Airtel Products undertaken in 2017 evidenced by Airtime scratch card and Electronic, <strong><em>E-Recharge</em></strong> Airtime among other forms to encourage <em>R.T.I.T</em> among other products in Telecom Companies and other Business Enterprises. The research comprises of the following areas among which included a detailed focus on a <strong><em>Qualitative</em></strong> and <strong><em>Quantitative approach</em></strong> in obtaining different <strong><em>categories</em></strong> of Restocking Delays in form of <strong><em>Themes</em></strong> and <strong><em>Sub Themes</em></strong> encountered in the Distribution Supply Chain (<em>SC</em>) of <em>AA</em> that is contained in this paper. This research continues to capture an in-depth explanation of the <strong><em>Managerial</em></strong> and <strong><em>Operational</em></strong> causes of restocking delays in respect to <em>AA</em>. Similarly, fast consumer products and services other than <em>AA</em> require a solution to <strong><em>Restocking Delays</em></strong> through implementation of Real Time Inventory Tracking Model (<em>R.T.I.T.M</em>) of <em>AA</em> among Distributor Companies (<em>DCs</em>). This paper also elaborated on Literature, Methodology and Findings obtained from the study. The <strong><em>results</em></strong> were obtained from <strong><em>regression analysis</em></strong> by using the Statistical Package for Social Sciences (<em>SPSS</em>) that showed a higher significance of <strong><em>Stock Turnover Period</em></strong> and<strong><em> Airtime Denomination</em></strong> as a contributor to Restocking Delays whereas <strong><em>Messages from Airtel</em></strong> Head office to the Distributor had a non-significant contribution to restocking Delays as in Figure 9. The research recommends a Model for <em>R.T.I.T</em> in Telecom Distribution <em>SC</em> of <em>AA </em>and Omnichannel Inventory Management (<em>OIM</em>) as a significant contributor to timely reliable inventory restocking and promotes higher sales among <em>DCs</em> and retailers through minimized Restocking Delays. It shows that the forces of Demand and Supply change over time with different tastes and preferences of customers. The imbalance in <em>AA</em> stock levels changes at given times due to unforeseen forces of consumer demand experienced by <em>DCs</em>, explained by the “<strong><em>Bullwhip Effect</em></strong>” due to information distortion in the Supply Chain (<em>SC</em>). 展开更多
关键词 Bullwhip effect Distribution Supply Chain Managerial causes Omnichannel Inventory Management Operational causes Restocking Delays and Telecom Company
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The cause of alienation between teacher and university students and companion affects each other obviously 被引量:1
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作者 Xuemei Lv 《Journal of Zhouyi Research》 2014年第4期76-78,共3页
关键词 大学生 原因 老师 教育体系 社会环境 信息交流 归属感 教师
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Human Papillomavirus—The Cause of Human Cervical Cancer
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作者 Ilija Barukcic 《Journal of Biosciences and Medicines》 2018年第4期106-125,共20页
Objective: Cervical cancer is the second most prevalent cancer in females worldwide. Infection with human papillomavirus (HPV) is regarded as the main risk factor of cervical cancer. One objective of this study was to... Objective: Cervical cancer is the second most prevalent cancer in females worldwide. Infection with human papillomavirus (HPV) is regarded as the main risk factor of cervical cancer. One objective of this study was to conduct a qualitative systematic review of some case-control studies and to examine the role of human papillomavirus (HPV) in the development of human cervical cancer (CC) beyond any reasonable doubt. Methods: We conducted a systematic review and re-analysis of some impressive key studies aimed to answer the following question. Is there a cause-effect relationship between human papillomavirus and cervical cancer? The method of the conditio sine qua non relationship was used to proof the hypothesis whether the presence of human papillomavirus guarantees the presence of cervical carcinoma. In other words, if human cervical cancer is present, then human papillomavirus is present too. The mathematical formula of the causal relationship k was used to proof the hypothesis, whether there is a cause-effect relationship between human papillomavirus and cervical carcinoma. Significance was indicated by a p-value of less than 0.05. Result: The studies analyzed (sample size N = 7657) were able to provide strict evidence that human papillomavirus is a necessary condition (a conditio sine qua non) of cervical carcinoma. Furthermore, the studies analyzed provide impressive evidence of a cause-effect relationship (k = +0.723669245, p value < 0.00001) between human papillomavirus and cervical carcinoma. Conclusion: Human papillomavirus is the cause of human cervical carcinoma. 展开更多
关键词 Human Papillomavirus Cervical Cancer cause effect Relationship causALITY
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根因分析法3C护理对消毒供应中心护理质控成效的影响
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作者 李晓云 邹玫 高丽真 《中国卫生标准管理》 2024年第5期175-178,共4页
目的探讨消毒供应中心在开展护理管理过程中运用根因分析法3C护理模式对降低护理缺陷事件发生率以及质控成效的影响。方法福建省立医院消毒供应中心2022年6月1日开始运用根因分析法进行3C护理,分析实施前后各1年(2021年6月—2023年6月)... 目的探讨消毒供应中心在开展护理管理过程中运用根因分析法3C护理模式对降低护理缺陷事件发生率以及质控成效的影响。方法福建省立医院消毒供应中心2022年6月1日开始运用根因分析法进行3C护理,分析实施前后各1年(2021年6月—2023年6月)消毒供应中心护理管理工作质量。结果评估实施前后各护理管理质量,实施后环境管理(93.01±3.11)分、安全管理(94.15±1.86)分、物品管理(92.11±1.86)分、检查管理(93.46±1.58)分,均明显高于管理前的(82.14±2.34)分、(81.45±1.86)分、(83.45±1.45)分、(80.05±2.34)分(P<0.05)。随机抽选两观察时间段患者500例,实施后护理缺陷事件发生率为0.20%,低于实施前的5.00%(P<0.05)。实施后院内感染率为1.00%,低于实施前的9.40%(P<0.05)。实施后对消毒供应中心护理工作满意度为98.00%,高于实施前的92.00%(P<0.05)。结论消毒供应中心在开展日常护理管理过程中将根因分析法3C护理进行运用,可以降低护理缺陷事件发生率,提升质量控制效果,对于提升消毒供应中心护理工作质量有重要作用。 展开更多
关键词 根因分析法 3C护理 消毒供应中心 护理缺陷事件 质控成效 护理满意度
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基于AIE效应的内源性硫化氢荧光探针的研究进展
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作者 刘冰弥 宫达诚 +1 位作者 田璐 生慧 《辽宁大学学报(自然科学版)》 CAS 2024年第2期130-140,共11页
合理设计监测内源性硫化氢的荧光探针分子有助于充分了解其生理和病理功能.目前,在研的检测硫化氢的小分子荧光探针多存在聚集诱导猝灭效应,因此克服此缺陷的聚集诱导发光效应荧光探针的研究受到越来越多的关注.本文结合研究实践简要综... 合理设计监测内源性硫化氢的荧光探针分子有助于充分了解其生理和病理功能.目前,在研的检测硫化氢的小分子荧光探针多存在聚集诱导猝灭效应,因此克服此缺陷的聚集诱导发光效应荧光探针的研究受到越来越多的关注.本文结合研究实践简要综述了近几年具有聚集诱导发光效应的化学反应型硫化氢活体成像荧光探针的研究进展及设计思想并进行展望,以期对该领域研究提供一些借鉴和思考. 展开更多
关键词 内源性硫化氢 聚集诱导发光效应 聚集诱导猝灭效应 荧光探针 活体成像
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玉米“适应性负效应”现象探讨——西南喀斯特石漠化成因新解
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作者 杨成 李秀英 《怀化学院学报》 2024年第3期26-33,共8页
南方的石漠化,北方的沙漠化,是困扰中国的两大生态环境问题。为探寻西南喀斯特石漠化的形成原因,利用文献法、参与式田野调查法以及经验实证法,梳理了近四十年来西南喀斯特石漠化形成的各种成因说,并以贵州为例,详细论述了石漠化形成的... 南方的石漠化,北方的沙漠化,是困扰中国的两大生态环境问题。为探寻西南喀斯特石漠化的形成原因,利用文献法、参与式田野调查法以及经验实证法,梳理了近四十年来西南喀斯特石漠化形成的各种成因说,并以贵州为例,详细论述了石漠化形成的三个阶段,以及石漠化与玉米的关系。在此基础上揭示了玉米在石漠化地区存在“适应性负效应”,合理地解释了西南喀斯特石漠化形成原因。此观点的提出,可为西南喀斯特石漠化形成原因做出新的阐释,同时也可为西南石漠化治理提供理论支持与科学依据。 展开更多
关键词 西南喀斯特 石漠化成因 玉米种植 适应性负效应
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基于医疗失效模式与效应分析框架的社区2型糖尿病临床惰性形成原因及对策研究
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作者 李殿江 潘恩春 +4 位作者 王苗苗 孙中明 文进博 樊宏 沈冲 《中国全科医学》 北大核心 2024年第5期570-576,共7页
背景自2009年起,社区2型糖尿病(T2DM)健康管理作为国家基本公共卫生服务项目在全国得到推广实施,但由于临床惰性(即发现问题未能及时采取干预措施)的影响,造成患者血糖长期控制效果不佳,因此如何克服临床惰性以提高血糖控制率是优化糖... 背景自2009年起,社区2型糖尿病(T2DM)健康管理作为国家基本公共卫生服务项目在全国得到推广实施,但由于临床惰性(即发现问题未能及时采取干预措施)的影响,造成患者血糖长期控制效果不佳,因此如何克服临床惰性以提高血糖控制率是优化糖尿病健康管理所面临的一项重要而紧迫的任务。目的识别社区T2DM健康管理过程中临床惰性发生的关键失效模式,系统分析关键失效模式的发生原因,并提出相应的干预对策措施。方法立足社区实情,以医疗失效模式与效应分析(HFMEA)框架为指导,通过实地调研、访谈及文献归纳分析法初步明确社区T2DM健康管理流程、临床惰性发生的原因及干预措施。文献检索时间为2020-01-01—2023-06-30。在此基础上,应用德尔菲法,选择16名专家于2022-01-10—02-25期间进行两轮专家咨询,最终确定社区T2DM健康管理过程中临床惰性发生的关键失效模式、发生原因和干预措施。结果第一轮和第二轮专家权威系数分别为0.791和0.729。最终通过计算风险优先指数(RPN)量化确定了社区T2DM健康管理过程中临床惰性发生的10个关键失效模式,按RPN从大到小,依次为未(及时)胰岛素治疗、未(及时)戒酒、未(及时)常规转诊、未(及时)戒烟、未(及时)紧急转诊、未(及时)三联治疗、未(及时)控制体质量、未(及时)调整膳食结构、未(及时)二联治疗和未(及时)发现低血糖,并从患者、医生及卫生系统层面阐明了关键失效模式形成的根本原因,制定了针对性的干预措施。结论制定的临床惰性干预措施具有较高的科学性和权威性,为优化社区T2DM健康管理模式奠定了基础。 展开更多
关键词 糖尿病 2型 健康管理 临床惰性 形成原因 社区 医疗失效模式与效应分析
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