Cortical hem signaling center: functions, development, and potential implications for evolution and brain disorders

Development of the telencephalon relies upon several signaling centers-localized cellular populations that supply secreted factors to pattern the cortical neuroepithelium.One such signaling center is the cortical hem,which arises during embryonic development at the telencephalic dorsal midline,adjacent to the choroid plexus and hippocampal primordium(Figure 1A).While the cortical hem has also been described in reptiles and birds,most of our knowledge about the developmental roles of the cortical hem is derived from the analysis in mice.The cortical hem produces several types of secreted molecules,including wingless-related integration site(Wnt)and bone morphogenetic(Bmp)proteins.The cortical hem is particularly important for the development of the hippocampus,which is involved in learning and memory,and the neocortex,which is the most complex brain region that mediates multiple types of behavior and higher cognitive functions(Mangale et al.,2008;Dal-Valle-Anton and Borrell,2022).

Construction and realization of the knowledge base and inference engine of an IDSS model for air-conditioning cooling/heating sources selection

The knowledge representation mode and inference control strategy were analyzed according to the specialties of air-conditioning cooling/heating sources selection. The constructing idea and working procedure for knowledge base and inference engine were proposed while the realization technique of the C language was discussed. An intelligent decision support system (IDSS) model based on such knowledge representation and inference mechanism was developed by domain engineers. The model was verified to have a small kernel and powerful capability in list processing and data driving, which was successfully used in the design of a cooling/heating sources system for a large-sized office building.

Application of water loop variable refrigerant flow air-conditioning system in large-scale buildings in northern China

A water loop variable refrigerant flow（WLVRF）air-conditioning system is designed to be applied in large-scale buildings in northern China.The system is energy saving and it is an integrated system consisting of a variable refrigerant flow（VRF）air-conditioning unit,a water loop and an air source heat pump.The water loop transports energy among different regions in the buildings instead of refrigerant pipes,decreasing the scale of the VRF air-conditioning unit and improving the performance.Previous models for refrigerants and building loads are cited in this investigation.Mathematical models of major equipment and other elements of the system are established using the lumped parameter method based on the DATAFIT software and the MATLAB software.The performance of the WLVRF system is simulated.The initial investments and the running costs are calculated based on the results of market research.Finally,a contrast is carried out between the WLVRF system and the traditional VRF system.The results show that the WLVRF system has a better working condition and lower running costs than the traditional VRF system.

Entropy Assessment on Environmental Influence of Condense Heat in Recovery System in Air-Conditioning Refrigerating Machine

This paper presented an entropy evaluation method for the influences of condense heat recovery system on the environment.Aiming at the damage of the condense heat to the environment,an entropy of resource loss and an emission entropy from the condense heat recovery system in the air conditioning refrigerating machine were introduced.For the evaluation of the entropies,we developed a new algorithm for the parameter identification,called the composite influence coefficient,based on the Least Squares Support Vector Machine method.By simulation,the numerical experiments shows that the Least Squares Support Vector Machine method is one of the powerful methods for the parameter identification to compute the damage entropy of the condense heat,with the largest training error being-0.025(the relative error being-3.56%),and the biggest test error being 0.015(the relative error being 2.5%).

Impact of summer office set air-conditioning temperature on energy consumption and thermal comfort

To explore the relationship between summer office set air-conditioning temperature and energy consumption related to air conditioning use to provide human thermal comfort,a comparison experiment was conducted in three similar offices at temperatures of 24,26 and 28 ℃ respectively. A thermal comfort questionnaire survey was conducted. It is demonstrated that air-conditioner energy consumption at the set temperature of 28 ℃ is 113% and 271% lower than at 26 ℃ and 24 ℃,respectively. A linear relationship exists between air-conditioner energy consumption and the indoor and outdoor temperature difference. When comfortably dressed,over 80% of research participants accept the set temperature of 28 ℃. The regression analysis leads to a neutral temperature of 26.2 ℃ and an acceptable temperature of 28.2 ℃ for over 80% of the research participants subjects,indicating that the current 26 ℃ set temperature for offices in summer,required by Chinese General Office of the State Council,can be increased to 28 ℃. Moreover,analysis of predicted mean vote(PMV) index shows that a set temperature of 27 ℃,not 26 ℃,is sufficiently comfortable for office staff wearing long-sleeve shirts,long pants and leather shoes.

Genetic Optimization Algorithm of PID Decoupling Control for VAV Air-Conditioning System

Variable-air-volume (VAV) air-conditioning system is a multi-variable system and has multi coupling control loops. While all of the control loops are working together, they interfere and influence each other. A multivariable decoupling PID controller is designed for VAV air-conditioning system. Diagonal matrix decoupling method is employed to eliminate the coupling between the loop of supply air temperature and that of thermal-space air temperature. The PID controller parameters are optimized by means of an improved genetic algorithm in floating point representations to obtain better performance. The population in the improved genetic algorithm mutates before crossover, which is helpful for the convergence. Additionally the micro mutation algorithm is proposed and applied to improve the convergence during the later evolution. To search the best parameters, the optimized parameters ranges should be amplified 10 times the initial ideal parameters. The simulation and experiment results show that the decoupling control system is effective and feasible. The method can overcome the strong coupling feature of the system and has shorter governing time and less over-shoot than non-optimization PID control.

Selection of Weather Parameters for Air-Conditioning System Design for Buildings with Long Thermal Lag

Two building factors-a longer thermal lag of more than one hour for building envelops and a lag of indoor radiation to convert into cooling load-have impact on the instantaneous heat input and instantaneous cooling load.So the two factors should be taken into account when selecting the weather parameters for air-conditioning system design.This paper developed a new statistic method for the rational selection of coincident solar irradiance,dry-bulb and wet-bulb temperatures.The method was applied to historic weather records of 25 years in Hong Kong to generate coincident design weather data.And the results show that traditional design solar irradiance,dry-bulb and wet-bulb temperatures may be significantly overestimated in many conditions,and the design weather data for the three different constructions is not kept constant.

The Experiment and Simulation of Solid Desiccant Dehumidification for Air-Conditioning System in a Tropical Humid Climate

The aim of this research was to study and design a solid desiccant dehumidification system suitable for tropical climate to reduce the latent load of air-conditioning system and improve the thermal comfort. Different dehumidifiers such as desiccant column and desiccant wheel were investigated. The ANSYS and TRASYS software were used to predict the results of dehumidifiers and the desiccant cooling systems, respectively. The desiccant bed contained approximately 15 kg of silica-gel, with 3 mm average diameter. Results indicated that the pressure drop and the adsorption rate of desiccant column are usually higher than those of the desiccant wheel. The feasible and practical adsorption rate of desiccant wheel was 0.102 kgw/h at air flow rate 1.0 kg/min, regenerated air temperature of 55?C and at a wheel speed of 2.5 rpm. The humidity ratio of conditioning space and cooling load of split-type air conditioner was decreased to 0.002 kgw/kgda (14%) and 0.71 kWth (19.26%), respectively. Consequently, the thermal comfort was improved from 0.5 PMV (10.12% PPD) to 0.3 PMV (7.04% PPD).

An Energy-Saving Control Strategy on Central Air-Conditioning System

An energy-saving control strategy based on predictive control for central air-conditioning systems is proposed in this paper. The cold load model is developed to describe the dynamic characteristics of temperature control systems, and then parameters in the cold load model and in the central air-conditioning system model are estimated. Generalized predictive control (GPC) is used to establish an optimization model to minimize the consumption of energy and the control error of temperature. The simulated annealing (SA) algorithm, combined with quadratic programming, is adopted to solve the optimal problem. Contrasted with the simulation of traditional PID control, the results prove the effectiveness of this proposed strategy.

Application of Fuzzy Comprehensive Evaluation to Air-conditioning Competitive Power Analysis

As the conceptual design of air-conditioning is done using the theory of Quality Function Deployment (QFD),cus- tomer requirements should be understood and the product competitive power be analyzed as exactly as possible for new product de- signing.Lots of information in the process of this research is fuzzy and uncertain,but traditional QFD can not deal with it well. Fuzzy theory can solve the problem.So a fuzzy model for analyzing product competitive power is formulated in this paper to im- prove traditional QFD,after that it is applied to analyze air-conditioning competitive power.When air-conditioning competitive power is analyzed using this model,firstly the importance weight of the customer requirements o fair-conditioning is determined us- ing the Analytic Hierarchy Process (AHP) weighting process,then air-conditloning competitive power is evaluated using fuzzy comprehensive evaluation.It is proved that the model is feasible and has good applicability.

Experimental Study of Energy-Saving Air-Conditioner with Hot Water

Energy-saving air-conditioner with hot water is an air source heat pump air-conditioner,which can also supply hot water.The hot water is heated by a double pipe condenser connected with an air-cooled condenser in series in the system.This experiment of the energy-saving air-conditioner was carried out in the enthalpy-difference air-conditioner laboratory.The hot water temperature and the compressor's discharge and suction pressure were recorded in the working condition,where the ambient temperature was at 43 ℃,35 ℃,21 ℃,7 ℃,and 2 ℃ separately.The results showed that the system operated stably and reliably.This system can supply 240 L hot water at 50 ℃ in the whole year,and its coefficience of performance(COP)is much higher than the conventional air source heat pump system.Its energy conservation was proved by comparing the thermal efficiency with other sourece water heaters.

Application of Dual Throttling Air-Conditioning System to Explosion-Proof Frequency Converter

An explosion-proof dual throttling air-conditioning system was put forward to solve the heat dissipation and internal dewing problems of explosion-proof frequency converter in the underground coal mine. This study investigated the feasibility and benefits of explosion-proof dual throttling cooling and dehumidification air-conditioning system applied to the explosion-proof frequency converter. The physical model of dual throttling air-conditioning system was established and its performance parameter was described by mathematical method. The design calculation of the system has also been done. The experimental result showed that the system reached the steady state at the refrigeration mode after running 45 min, and the maximum internal temperature of the flame-proof cavity was 31.0 ℃. The system reached the steady state at the dehumidification mode after running 37 min. The maximum internal relative humidity and temperature of the flame-proof cavity were 33.4% and 36.3 ℃, respectively. Therefore, the proposed system had excellent ability of heat dissipation and avoided internal dewing. Compared with water cooling system, it was more energy-saving and economical. The airflow field of dual throttling air-conditioning system was also studied by CFD simulation. It was found that the result of CFD numerical simulation was highly consistent with the experimental data.

Simulation of Artificial Intelligence for Automotive Air-conditioning System

The artificial intelligence is applied to the simulation of the automotive air-conditioning system ( AACS )According to the system's characteristics a model of AACS, based on neural network, is developed. Different control methods of AACS are discussed through simulation based on this model. The result shows that the neural- fuzzy control is the best one compared with the on-off control and conventional fuzzy control method.It can make the compartment's temperature descend rapidly to the designed temperature and the fluctuation is small.

Energy performance assessment on central air-conditioning system of commercial building: A case study in China

Energy performance assessment on central air-conditioning system is essential to optimize operating, reduce operating costs, improve indoor environmental quality, and determine whether the retrofitting of the equipment is necessary. But it is difficult to evaluate it reasonably and comprehensively due to its complexity. A "holistic" approach was discussed to evaluate the energy performance of central air-conditioning system for an extra-large commercial building in a subtropical city. All procedures were described in detail, including field investigation method, field measurement instruments, data processing and data analyzing. The main factors affecting energy consumption of air-conditioning system were analyzed and the annual cooling-energy use intensity of this building was calculated and also compared with other shopping malls and other types of buildings in Guangzhou. And COP(coefficient of performance) of chiller, water transfer factor of chilled water system and cooling water system were taken into consideration. At last, the thermal comfort and indoor air quality issues were addressed. The results show that the chilled water pumps are over-sized and the indoor environmental quality should be improved. The purpose of this work is to provide reference for energy performance assessment method for air-conditioning system.

Research on the Arrangement of Dew Point Temperature Detectors of Capillary Plane Radiation Air-Conditioning

Based on analysis of the reason and process of condensation on ceiling radiant cooling panels, two kinds of arrangement of detectors are put forward. The physical model is established, the results show that detectors are arranged as the form of triangle is more suitable. It can not only satisfy the use requirement but also it is economical and practical. Finally we can conclude that the inlet water temperature 0.5°C higher than dew point temperature is safe and reliable.

Analysis of Solar Direct-Driven Organic Rankine Cycle Powered Vapor Compression Cooling System Combined with Electric Motor for Office Building Air-Conditioning

Solar energy powered organic Rankine cycle vapor compression cycle(ORC-VCC)is a good alternative to convert solar heat into a cooling effect.In this study,an ORC-VCC system driven by solar energy combined with electric motor is proposed to ensure smooth operation under the conditions that solar radiation is unstable and discontinuous,and an office building located in Guangzhou,China is selected as a case study.The results show that beam solar radiation and generation temperature have considerable effects on the system performance.There is an optimal generation temperature at which the system achieves optimum performance.Also,as a key indicator,the cooling power per square meter collector should be considered in the hybrid solar cooling system in design process.Compared to the vapor compression cooling system,the hybrid cooling system can save almost 68.23%of electricity consumption.

Analysis of Fresh Air Volume of Air-conditioning System for Railway Vehicles

The relevant standard requirements both in domestic and abroad provide the basis for designing air-conditioning system of railway vehicles present. However, there are great differences in the fresh air volume indicators among different standards requirements, and the requirements of each vehicle procurement contracts are also different. The design of air-conditioning become difficult above these. In this paper, the fresh air volume of different type railway vehicles is analyzed from health and equipment electricity consumption according to the railway vehicles air-conditioning system standard requirements in domestic and abroad. Some advises for designing air-conditioning system of railway vehicles through the fresh air volume calculation and comparison for domestic air-conditioning system of railway vehicles was provided.

Activating d^(10)electronic configuration to regulate p-band centers as efficient active sites for solar energy conversion into H_(2)by surface atomic arrangement

Relationship between the activity for photocatalytic H_(2)O overall splitting(HOS)and the electron occupancy on d orbits of the active component in photocatalysts shows volcanic diagram,and specially the d^(10)electronic configuration in valley bottom exhibits inert activity,which seriously fetters the development of catalytic materials with great potentials.Herein,In d^(10)electronic configuration of In_(2)O_(3)was activated by phosphorus atoms replacing its lattice oxygen to regulate the collocation of the ascended In 5p-band(Inɛ5p)and descended O 2p-band(Oɛ2p)centers as efficient active sites for chemisorption to*OH and*H during forward HOS,respectively,along with a declined In 4d-band center(Inɛ4d)to inhibit its backward reaction.A stable STH efficiency of 2.23%under AM 1.5 G irradiation at 65°C has been obtained over the activated d^(10)electronic configuration with a lowered activation energy for H_(2)evolution,verified by femtosecond transient absorption spectroscopy,in situ diffuse reflectance infrared Fourier transform spectroscopy and theoretical calculations of dynamics.These findings devote to activating d^(10)electronic configuration for resolving the reaction energy barrier and dynamical bottleneck of forward HOS,which expands the exploration of high-efficiency catalytic materials.

Uniform isochronous center of a class of higher degree polynomial differential systems

In this paper,we give the necessary and sufficient conditions for a class of higher degree polynomial systems to have a uniform isochronous center.At the same time,we prove that for this system the composition conjecture is correct.

Preparing highly entangled states of nanodiamond rotation and NV center spin

A nanodiamond with an embedded nitrogen-vacancy(NV)center is one of the experimental systems that can be coherently manipulated within current technologies.Entanglement between NV center electron spin and mechanical rotation of the nanodiamond plays a fundamental role in building a quantum network connecting these microscopic and mesoscopic degrees of motions.Here we present a protocol to asymptotically prepare a highly entangled state of the total quantum angular momentum and electron spin by adiabatically boosting the external magnetic field.