利用导入神经回路内电、磁、光、声等物理因子作用来激发神经系统功能活性,进而改善神经疾病症状、提高生命质量的神经调控技术(neural control technology)在生命科学研究和医学临床诊疗中得到广泛应用.其中尤以低强度聚焦超声(low int...利用导入神经回路内电、磁、光、声等物理因子作用来激发神经系统功能活性,进而改善神经疾病症状、提高生命质量的神经调控技术(neural control technology)在生命科学研究和医学临床诊疗中得到广泛应用.其中尤以低强度聚焦超声(low intensity focused ultrasound,LIFU)具有非损伤性、高穿透能力与时空分辨等优势,更适合用作安全的神经调控物理刺激因子.目前LIFU用于神经调控研究已受到科学界高度关注,进行了大量动物与人类神经调控实验研究并取得可喜成果.本文分别从LIFU用于动物与人类中枢神经调控研究进展、神经调控机制、安全性问题和未来应用前景等方面介绍评述,以期为神经调控研究与应用提供参考.展开更多
The vertical focusing is one of the primary problems in the central region of cyclotrons. This focusing effect brought about by the magnetic field is inclined to be weak near the center of the machine due to the fact ...The vertical focusing is one of the primary problems in the central region of cyclotrons. This focusing effect brought about by the magnetic field is inclined to be weak near the center of the machine due to the fact that the flutter is small, while the electric focusing forces incurred from the dee gaps become very strong. Since the electric focusing effect is dependent on the RF phase, we have proceeded to carry out analytical calculations and numerical simulation about the vertical focusing in the central region of CYCIAE100, including magnetic focusing, electric focusing and the defocusing effect from the space charge effect. All the results have been used for the design of the central region for CYCIAE-100 and a good vertical focusing has been obtained.展开更多
文摘The vertical focusing is one of the primary problems in the central region of cyclotrons. This focusing effect brought about by the magnetic field is inclined to be weak near the center of the machine due to the fact that the flutter is small, while the electric focusing forces incurred from the dee gaps become very strong. Since the electric focusing effect is dependent on the RF phase, we have proceeded to carry out analytical calculations and numerical simulation about the vertical focusing in the central region of CYCIAE100, including magnetic focusing, electric focusing and the defocusing effect from the space charge effect. All the results have been used for the design of the central region for CYCIAE-100 and a good vertical focusing has been obtained.
