Background: To compare central corneal thickness (CCT) values measured in diabetic eyes and compare the CCT values in normal patients without diabetes. Methods: A total of 83 diabetic patients and 83 non-diabetic pati...Background: To compare central corneal thickness (CCT) values measured in diabetic eyes and compare the CCT values in normal patients without diabetes. Methods: A total of 83 diabetic patients and 83 non-diabetic patients were prospectively enrolled in this comparative case series. CCT was measured using a Topcon CT-1P non-contact automated pachymeter, and values were compared. Results: Mean age was 57 ± 11 years, with a range of 23 and 80 years. The mean CCT was 508.87 ± 35.83 μm for diabetic patients and 513.41 ± 37.22 μm for non-diabetic patients. There was no statistically significant difference between the CCT of diabetic patients compared to non-diabetic patients (p = 0.260). We did not find a significant correlation between the CCT of diabetic patients and clinical characteristics of diabetes. However, there was a positive and statistically significant linear correlation between the CCT of diabetic patients and intra ocular pressure (IOP). Conclusion: The mean CCT in diabetic patients was lower than in non-diabetic control patients, although there was no statistically significant difference.展开更多
Objective Central obesity is considered to be a central component of metabolic syndrome. Waist circumference （WC） has been widely used as a simple indicator of central obesity. This study is aimed to evaluate the se...Objective Central obesity is considered to be a central component of metabolic syndrome. Waist circumference （WC） has been widely used as a simple indicator of central obesity. This study is aimed to evaluate the sensitivity of WC cut-off values for predicting metabolic risk factors in middle-aged Chinese. Methods The study involved 923 subjects aged according to the Chinese Joint Committee for 40-65 years. The metabolic risk factors were defined Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. WC cut-off 85-90 cm and 〉90 cm were used as cut-off values of central pre-obesity and central obesity in males, respectively, while WC 80-85 cm and 〉85 cm were used as cut-off values of central pre-obesity and central obesity in females. Results First, WC values corresponding to body mass index （BMI） 24 kg/m2 and visceral fat area （VFA） 80 cm2 were 88.55 cm and 88.51 cm in males, and 82.46 cm and 82.52 cm in females respectively. Second, receiver operating characteristic curves showed that the optimal WC cut-off of value was 88.75 cm in males, higher than that in females （81.75 cm）. Third, the subjects with higher WC values were more likely to have accumulating metabolic risk factors. The prevalence of metabolic risk factors increased linearly and significantly in relation to WC levels. Conclusion WC cut-off values of central pre-/central obesity are optimal to predict multiple metabolic risk factors.展开更多
目的总结血液肿瘤患者PICC相关并发症预防的最佳证据,为临床实践提供参考。方法系统检索中国知网、万方数据库、维普数据库、中国生物医学文献数据库、医脉通、美国国立指南库、英国国家卫生与临床优化研究所网站、乔安娜布里格斯研究所...目的总结血液肿瘤患者PICC相关并发症预防的最佳证据,为临床实践提供参考。方法系统检索中国知网、万方数据库、维普数据库、中国生物医学文献数据库、医脉通、美国国立指南库、英国国家卫生与临床优化研究所网站、乔安娜布里格斯研究所(JBI)数据库、国际指南协作网、苏格兰校际指南网站、WHO网站、BMJ、Up To Date、Embase、PubMed、Web of Science、Cochrane Library关于血液科肿瘤患者PICC并发症预防的相关文献,检索时间为建库至2022年6月30日,对符合纳入排除标准的文献进行质量评价、证据分级及整合。结果最终纳入11篇文献,其中指南3篇、系统评价3篇、干预性研究2篇、专家共识3篇,总结出包括PICC评估与管理、置管前预防、置管中预防、置管后预防和健康教育5个方面的31条证据。结论本研究总结的血液肿瘤患者PICC相关并发症预防的最佳证据具有良好的科学性和系统性,可为提高患者治疗效果、减轻其经济负担提供循证依据,但应结合临床现况,针对性地运用最佳证据。展开更多
文摘Background: To compare central corneal thickness (CCT) values measured in diabetic eyes and compare the CCT values in normal patients without diabetes. Methods: A total of 83 diabetic patients and 83 non-diabetic patients were prospectively enrolled in this comparative case series. CCT was measured using a Topcon CT-1P non-contact automated pachymeter, and values were compared. Results: Mean age was 57 ± 11 years, with a range of 23 and 80 years. The mean CCT was 508.87 ± 35.83 μm for diabetic patients and 513.41 ± 37.22 μm for non-diabetic patients. There was no statistically significant difference between the CCT of diabetic patients compared to non-diabetic patients (p = 0.260). We did not find a significant correlation between the CCT of diabetic patients and clinical characteristics of diabetes. However, there was a positive and statistically significant linear correlation between the CCT of diabetic patients and intra ocular pressure (IOP). Conclusion: The mean CCT in diabetic patients was lower than in non-diabetic control patients, although there was no statistically significant difference.
基金supported by the Major Science and Technology Project of Zhejiang Province(Grant NO.2009C03010-4)the National Key Technology R&D Program of China(Grants No.2012BAI02B03 and No.2009BAI80B00)
文摘Objective Central obesity is considered to be a central component of metabolic syndrome. Waist circumference （WC） has been widely used as a simple indicator of central obesity. This study is aimed to evaluate the sensitivity of WC cut-off values for predicting metabolic risk factors in middle-aged Chinese. Methods The study involved 923 subjects aged according to the Chinese Joint Committee for 40-65 years. The metabolic risk factors were defined Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. WC cut-off 85-90 cm and 〉90 cm were used as cut-off values of central pre-obesity and central obesity in males, respectively, while WC 80-85 cm and 〉85 cm were used as cut-off values of central pre-obesity and central obesity in females. Results First, WC values corresponding to body mass index （BMI） 24 kg/m2 and visceral fat area （VFA） 80 cm2 were 88.55 cm and 88.51 cm in males, and 82.46 cm and 82.52 cm in females respectively. Second, receiver operating characteristic curves showed that the optimal WC cut-off of value was 88.75 cm in males, higher than that in females （81.75 cm）. Third, the subjects with higher WC values were more likely to have accumulating metabolic risk factors. The prevalence of metabolic risk factors increased linearly and significantly in relation to WC levels. Conclusion WC cut-off values of central pre-/central obesity are optimal to predict multiple metabolic risk factors.
文摘目的总结血液肿瘤患者PICC相关并发症预防的最佳证据,为临床实践提供参考。方法系统检索中国知网、万方数据库、维普数据库、中国生物医学文献数据库、医脉通、美国国立指南库、英国国家卫生与临床优化研究所网站、乔安娜布里格斯研究所(JBI)数据库、国际指南协作网、苏格兰校际指南网站、WHO网站、BMJ、Up To Date、Embase、PubMed、Web of Science、Cochrane Library关于血液科肿瘤患者PICC并发症预防的相关文献,检索时间为建库至2022年6月30日,对符合纳入排除标准的文献进行质量评价、证据分级及整合。结果最终纳入11篇文献,其中指南3篇、系统评价3篇、干预性研究2篇、专家共识3篇,总结出包括PICC评估与管理、置管前预防、置管中预防、置管后预防和健康教育5个方面的31条证据。结论本研究总结的血液肿瘤患者PICC相关并发症预防的最佳证据具有良好的科学性和系统性,可为提高患者治疗效果、减轻其经济负担提供循证依据,但应结合临床现况,针对性地运用最佳证据。
