In colon cancer surgery,ensuring the complete removal of the primary tumor and draining lymph nodes is crucial.Lymphatic drainage in the colon follows the vascular supply,typically progressing from pericolic to paraao...In colon cancer surgery,ensuring the complete removal of the primary tumor and draining lymph nodes is crucial.Lymphatic drainage in the colon follows the vascular supply,typically progressing from pericolic to paraaortic lymph nodes.While NCCN guidelines recommend the removal of 10-12 lymph nodes for ade-quate oncological resection,achieving complete oncological resection involves more than just meeting these numerical targets.Various techniques have been developed and studied over time to attain optimal oncological outcomes.A key technique central to this goal is identifying the ileocolic vessels at their origin from the superior mesenteric vessels.Complete excision of the visceral and parietal mesocolon ensures the intact removal of the specimen,while D3 lymphade-nectomy targets all draining regional lymph nodes.Although these principles emphasize different aspects,they ultimately converge to achieve the same goal of complete oncological resection.This article aims to simplify the surgical steps that align with the principle of central vascular ligation and mesocolon mobilization while ensuring adequate D3 dissection.展开更多
Since the 19th century,appropriate lymphadenectomy has been considered a cornerstone of oncologic surgery and one of the most important prognostic factors.This approach can be applied to any surgery for gastrointestin...Since the 19th century,appropriate lymphadenectomy has been considered a cornerstone of oncologic surgery and one of the most important prognostic factors.This approach can be applied to any surgery for gastrointestinal cancer.During surgery for colon and rectal cancer,an adequate portion of the mesentery is removed together with the segment of bowel affected by the disease.The adequate number of lymph nodes to be removed is standardized and reported by several guidelines.It is mandatory to determine the appropriate extent of lymphadenectomy and to balance its oncological benefits with the increased morbidity associated with its execution in cancer patients.Our review focuses on the concept of“complete mesenteric excision(CME)with central vascular ligation(CVL),”a radical lymphadenectomy for colorectal cancer that has gained increasing interest in recent years.The aim of this study was to evaluate the evolution of this approach over the years,its potential oncologic benefits and potential risks,and the improvements offered by laparoscopic techniques.Theoretical advantages of CME are improved local-relapse rates due to complete removal of the intact mesocolic fascia and improved distance recurrence rates due to ligation of vessels at their origin(CVL)which guarantees removal of a larger number of lymph nodes.The development and worldwide diffusion of laparoscopic techniques minimized postoperative trauma in oncologic surgery,providing the same oncologic results as open surgery.This has been widely applied to colorectal cancer surgery;however,CME entails a technical complexity that can limit its wide minimally-invasive application. This review analyzesresults of these procedures in terms of oncological outcomes, technical feasibilityand complexity, especially within the context of minimally invasive surgery.展开更多
We give a local analytic characterization that a minimal surface in the 3-sphere S3 C R4 defined by an irreducible cubic polynomial is one of the Lawson＇s minimal tori. This provides an alternative proof of the resul...We give a local analytic characterization that a minimal surface in the 3-sphere S3 C R4 defined by an irreducible cubic polynomial is one of the Lawson＇s minimal tori. This provides an alternative proof of the result by Perdomo （Characterization of order 3 algebraic immersed minimal surfaces of S3, Geom. Dedicata 129 （2007）, 23 34）.展开更多
With rapid development of urbanization and regional interaction and interdependence, regional urban agglomeration planning becomes more and more important in China, in order to promote integrated development of variou...With rapid development of urbanization and regional interaction and interdependence, regional urban agglomeration planning becomes more and more important in China, in order to promote integrated development of various cities with close interrelationship. However, it is still arguable academically on how to define the boundary or which cities to be included for the urban agglomeration of a region. This paper aims to shed lights on how to identify urban spheres of influence scientifically by introducing field modeling method and by practicing a case study on 168 cities in Central China. In our field modeling method, the influence intensities of cities were measured by a compre-ensive index and urban spheres of influence were represented spatially by field intensity. Then, their classification and spatial distribution characteristics of study area in 2007 were identified and explored by using GIS and statistical methods. The result showed that： 1） Wuhan is the absolute dominant city in Central China; 2） the provincial capital cities dominate their own provinces and there are no other lower grade agglomeration centers; and 3） the basic types of organization form of urban sphere of influence are single-polar type, agglomeration type, close-related group type and loose-related group type.展开更多
A number of urban and regional plans have been developed with the advancement of urbanization and regional integration, among which the delineation of sphere of urban influence and improvement of integration between t...A number of urban and regional plans have been developed with the advancement of urbanization and regional integration, among which the delineation of sphere of urban influence and improvement of integration between the city and its hinterland have be- come vital important for guiding practices. In terms of delineating sphere of urban influence, existing studies have been focused on static study by using single year data or single method, resulting in a lack of time-series longitudinal analysis or comprehensive analysis based on multiple methods This study emphasizes on comparing two methods from both the theoretical and empirical perspective. Both gravity model and improwd field model are applied to the selected study area for measurements and comparison, to explore their strengths and weaknesses. A research framework for comprehensive analysis on delineating sphere of urban influence is proposed. In the end, the differences of deli：aeating methods are illustrated and the feasibility of comprehensive analysis is discussed. Recommendations are provided for selecting appropriate methods for delineating sphere of urban influence or developing regional hierarchy system plans and urban spatial structure schemes.展开更多
For a finite group G, let S（G） be the set of minimal subgroups of odd order,which are complemented in G. It is proved that if every minimal subgroup X of odd orderof G which does not belong to S（G）, CG（X） is eit...For a finite group G, let S（G） be the set of minimal subgroups of odd order,which are complemented in G. It is proved that if every minimal subgroup X of odd orderof G which does not belong to S（G）, CG（X） is either subnormal or abnormal in G. Then Gsolvable.展开更多
目的:探讨流式细胞术(FCM)检测初诊儿童急性淋巴细胞白血病(ALL)患者的脑脊液状态及与预后的相关性。方法:回顾性分析华中科技大学同济医学院附属武汉儿童医院2020年9月至2021年12月资料完整的75例新诊断ALL患儿的临床资料、脑脊液常规...目的:探讨流式细胞术(FCM)检测初诊儿童急性淋巴细胞白血病(ALL)患者的脑脊液状态及与预后的相关性。方法:回顾性分析华中科技大学同济医学院附属武汉儿童医院2020年9月至2021年12月资料完整的75例新诊断ALL患儿的临床资料、脑脊液常规细胞学(CC)检查、不同时期骨髓及脑脊液微小残留病灶(MRD)等结果。通过FCM与CC对比分析脑脊液状态,分析初诊时不同脑脊液状态患儿的临床特征及其预后。结果:75例新诊断ALL患儿中,FCM检出16例(21%)中枢神经系统浸润(central nervous system infiltration,CNSI)阳性患儿,而CC检出异常幼稚细胞2例(3%),FCM检测CNSI阳性率明显高于常规细胞学检查(P<0.05)。与CNSI^(-)ALL患儿相比,CNSI^(+)ALL患儿初诊时的中位年龄更小[2.6(0.3-12.0)岁vs 4.5(0.8-14.5)岁]且血小板中位计数更低[23(2-180)×10^(9)/L vs 65(5-355)×10^(9)/L],具有统计学差异(P<0.05)。截至随访终点(2022年8月31日),4例ALL患儿死亡,其中CNSI^(+)患儿1例;复发3例,其中CNSI^(+)患儿1例。不同CNSI状态患儿的总体生存(OS)率及无复发生存(RFS)率均无明显统计学差异。结论:对使用FCM评估初诊ALL患儿的CNSI状态比CC更敏感。初诊时不同CNSI状态的ALL患儿接受积极治疗后OS率及RFS率无明显差异。展开更多
As a branch of applied mathematics, coding theory plays an important role. Among them, cyclic codes have attracted much attention because of their good algebraic structure and easy analysis performance. In this paper,...As a branch of applied mathematics, coding theory plays an important role. Among them, cyclic codes have attracted much attention because of their good algebraic structure and easy analysis performance. In this paper, we will study one class of cyclic codes over F<sub>3</sub>. Given the length and dimension, we show that it is optimal by proving its minimum distance is equal to 4, according to the Sphere Packing bound.展开更多
文摘In colon cancer surgery,ensuring the complete removal of the primary tumor and draining lymph nodes is crucial.Lymphatic drainage in the colon follows the vascular supply,typically progressing from pericolic to paraaortic lymph nodes.While NCCN guidelines recommend the removal of 10-12 lymph nodes for ade-quate oncological resection,achieving complete oncological resection involves more than just meeting these numerical targets.Various techniques have been developed and studied over time to attain optimal oncological outcomes.A key technique central to this goal is identifying the ileocolic vessels at their origin from the superior mesenteric vessels.Complete excision of the visceral and parietal mesocolon ensures the intact removal of the specimen,while D3 lymphade-nectomy targets all draining regional lymph nodes.Although these principles emphasize different aspects,they ultimately converge to achieve the same goal of complete oncological resection.This article aims to simplify the surgical steps that align with the principle of central vascular ligation and mesocolon mobilization while ensuring adequate D3 dissection.
文摘Since the 19th century,appropriate lymphadenectomy has been considered a cornerstone of oncologic surgery and one of the most important prognostic factors.This approach can be applied to any surgery for gastrointestinal cancer.During surgery for colon and rectal cancer,an adequate portion of the mesentery is removed together with the segment of bowel affected by the disease.The adequate number of lymph nodes to be removed is standardized and reported by several guidelines.It is mandatory to determine the appropriate extent of lymphadenectomy and to balance its oncological benefits with the increased morbidity associated with its execution in cancer patients.Our review focuses on the concept of“complete mesenteric excision(CME)with central vascular ligation(CVL),”a radical lymphadenectomy for colorectal cancer that has gained increasing interest in recent years.The aim of this study was to evaluate the evolution of this approach over the years,its potential oncologic benefits and potential risks,and the improvements offered by laparoscopic techniques.Theoretical advantages of CME are improved local-relapse rates due to complete removal of the intact mesocolic fascia and improved distance recurrence rates due to ligation of vessels at their origin(CVL)which guarantees removal of a larger number of lymph nodes.The development and worldwide diffusion of laparoscopic techniques minimized postoperative trauma in oncologic surgery,providing the same oncologic results as open surgery.This has been widely applied to colorectal cancer surgery;however,CME entails a technical complexity that can limit its wide minimally-invasive application. This review analyzesresults of these procedures in terms of oncological outcomes, technical feasibilityand complexity, especially within the context of minimally invasive surgery.
文摘We give a local analytic characterization that a minimal surface in the 3-sphere S3 C R4 defined by an irreducible cubic polynomial is one of the Lawson＇s minimal tori. This provides an alternative proof of the result by Perdomo （Characterization of order 3 algebraic immersed minimal surfaces of S3, Geom. Dedicata 129 （2007）, 23 34）.
基金Under the auspices of National Natural Science Foundation of China (No. 40971102)Knowledge Innovation Programs of Chinese Academy of Sciences (No. KZCX2-YW-322)Special Grant for Postgraduates' Scientific Innovation and Social Practice in 2008
文摘With rapid development of urbanization and regional interaction and interdependence, regional urban agglomeration planning becomes more and more important in China, in order to promote integrated development of various cities with close interrelationship. However, it is still arguable academically on how to define the boundary or which cities to be included for the urban agglomeration of a region. This paper aims to shed lights on how to identify urban spheres of influence scientifically by introducing field modeling method and by practicing a case study on 168 cities in Central China. In our field modeling method, the influence intensities of cities were measured by a compre-ensive index and urban spheres of influence were represented spatially by field intensity. Then, their classification and spatial distribution characteristics of study area in 2007 were identified and explored by using GIS and statistical methods. The result showed that： 1） Wuhan is the absolute dominant city in Central China; 2） the provincial capital cities dominate their own provinces and there are no other lower grade agglomeration centers; and 3） the basic types of organization form of urban sphere of influence are single-polar type, agglomeration type, close-related group type and loose-related group type.
基金Under the auspices of National Natural Science Foundation of China(No.40901088)
文摘A number of urban and regional plans have been developed with the advancement of urbanization and regional integration, among which the delineation of sphere of urban influence and improvement of integration between the city and its hinterland have be- come vital important for guiding practices. In terms of delineating sphere of urban influence, existing studies have been focused on static study by using single year data or single method, resulting in a lack of time-series longitudinal analysis or comprehensive analysis based on multiple methods This study emphasizes on comparing two methods from both the theoretical and empirical perspective. Both gravity model and improwd field model are applied to the selected study area for measurements and comparison, to explore their strengths and weaknesses. A research framework for comprehensive analysis on delineating sphere of urban influence is proposed. In the end, the differences of deli：aeating methods are illustrated and the feasibility of comprehensive analysis is discussed. Recommendations are provided for selecting appropriate methods for delineating sphere of urban influence or developing regional hierarchy system plans and urban spatial structure schemes.
基金Supported by the Natural Science Foundation of Guangxi Autonomous Region（0249001）
文摘For a finite group G, let S（G） be the set of minimal subgroups of odd order,which are complemented in G. It is proved that if every minimal subgroup X of odd orderof G which does not belong to S（G）, CG（X） is either subnormal or abnormal in G. Then Gsolvable.
文摘目的:探讨流式细胞术(FCM)检测初诊儿童急性淋巴细胞白血病(ALL)患者的脑脊液状态及与预后的相关性。方法:回顾性分析华中科技大学同济医学院附属武汉儿童医院2020年9月至2021年12月资料完整的75例新诊断ALL患儿的临床资料、脑脊液常规细胞学(CC)检查、不同时期骨髓及脑脊液微小残留病灶(MRD)等结果。通过FCM与CC对比分析脑脊液状态,分析初诊时不同脑脊液状态患儿的临床特征及其预后。结果:75例新诊断ALL患儿中,FCM检出16例(21%)中枢神经系统浸润(central nervous system infiltration,CNSI)阳性患儿,而CC检出异常幼稚细胞2例(3%),FCM检测CNSI阳性率明显高于常规细胞学检查(P<0.05)。与CNSI^(-)ALL患儿相比,CNSI^(+)ALL患儿初诊时的中位年龄更小[2.6(0.3-12.0)岁vs 4.5(0.8-14.5)岁]且血小板中位计数更低[23(2-180)×10^(9)/L vs 65(5-355)×10^(9)/L],具有统计学差异(P<0.05)。截至随访终点(2022年8月31日),4例ALL患儿死亡,其中CNSI^(+)患儿1例;复发3例,其中CNSI^(+)患儿1例。不同CNSI状态患儿的总体生存(OS)率及无复发生存(RFS)率均无明显统计学差异。结论:对使用FCM评估初诊ALL患儿的CNSI状态比CC更敏感。初诊时不同CNSI状态的ALL患儿接受积极治疗后OS率及RFS率无明显差异。
文摘As a branch of applied mathematics, coding theory plays an important role. Among them, cyclic codes have attracted much attention because of their good algebraic structure and easy analysis performance. In this paper, we will study one class of cyclic codes over F<sub>3</sub>. Given the length and dimension, we show that it is optimal by proving its minimum distance is equal to 4, according to the Sphere Packing bound.
