Solvent extraction phenol from coal tar were carried out with novel composite YH-3 as extraction agent, and the high flux centrifugal extractor was used as extraction device. Under the premise of high phenol extractio...Solvent extraction phenol from coal tar were carried out with novel composite YH-3 as extraction agent, and the high flux centrifugal extractor was used as extraction device. Under the premise of high phenol extraction rate, composite YH-3 extraction agent reduces n-n interaction between phenolic compounds and aromatic hydrocarbons, thus decreasing the entrainment of neutral oil. The optimization of operation conditions, such as the diameter of heavy phase weir HWD, the flow ratio, the total flow rate and the rotation speed, are necessary. For single stage extraction experiment, the mass transfer efficiency was up to 84% while the rate of extraction agent loss was lower than 0.28% with the operation conditions of 29 mm of the heavy phase weir diameter （HWD）, 1：1-1.4：1 of the flow ratio range, 160-200 mL/min of the total flow rate and the rotation speed varied from 2200 to 2600 r/min. For three stage counter-current test, the mass transfer efficiency reached up to 92.6% with the optimum operation condition of 29 mm of the HWD, 1：1 of the flow ratio, 200 rnL/min of the total flow rate and 2400 r/rain of the rotation speed. The results indicated that phenol could be extracted effectively from coal tar in the process of multistage continuous count current centrifugal extraction.展开更多
In this study,extraction of p-cresol from the simulated wastewater has been studied using centrifugal extractors and QH-1 extractant.The distribution ratio of p-cresol was approximately 308.5 in the QH-1-p-cresol(pH=2...In this study,extraction of p-cresol from the simulated wastewater has been studied using centrifugal extractors and QH-1 extractant.The distribution ratio of p-cresol was approximately 308.5 in the QH-1-p-cresol(pH=2.0)system.The extraction stage efficiency of the single-stage centrifugal extractor was higher than 92%,and the extraction rate of the three-stage cascade was higher than 99%.When 15% NaOH was used for the stripping of p-cresol in QH-1 solution,the stripping rate of the three-stage cascade reached 100%.A mathematical model of multistage countercurrent extraction process that considers the phase volume change,extraction stage efficiency,and phase entrainment was used to simulate the extraction of p-cresol using centrifugal extractors.The calculated results using this model were in good agreement with the experimental results.展开更多
Continuous manufacturing is considered as one of the future trends of pharmaceutical engineering. In this work, continuous liquid-liquid extraction for sinomenine purification was realized with the usage of centrifuga...Continuous manufacturing is considered as one of the future trends of pharmaceutical engineering. In this work, continuous liquid-liquid extraction for sinomenine purification was realized with the usage of centrifugal extractors. Chloroform was used as the extractant because of the high distribution coefficient (>100). Higher extraction ratio can be obtained when using the centrifugal extractor of Model CWL50-N. The extraction ratio of the second-stage extraction was higher than that of the first-stage extraction. The extraction ratio of the second-stage countercurrent extraction was higher than that of second-stage cross-flow extraction. When chloroform phase was recycled for liquid-liquid extraction, the extraction ratio was also higher than 95%. This work can also be an example of continuous liquid-liquid extraction for the separation of other Chinese medicine components.展开更多
The annular centrifugal extractor(ACE)integrates mixing and separation.It has been widely used in many industrial fields because of its low residence time,compact structure,and high mass transfer efficiency.Most of th...The annular centrifugal extractor(ACE)integrates mixing and separation.It has been widely used in many industrial fields because of its low residence time,compact structure,and high mass transfer efficiency.Most of the literature has focused on flow instabilities,flow visualization,and computational fluid dynamics simulations.More recently,research on hydrodynamic behavior and structural optimization has received widespread attention.With the development of ACE technology,applications have been broadened into several new areas.Hence,this paper reviews research progress regarding ACE in terms of hydrodynamic characteristics and the structural improvements.The latest applications covering hydrometallurgy,nuclear fuel reprocessing,bio-extraction,catalytic reaction,and wastewater treatment are presented.We also evaluate future work in droplet breakup and coalescence mechanisms,structural improvements specific to different process requirements,scaling-up methods,and stability and reliability after scaling-up.展开更多
文摘Solvent extraction phenol from coal tar were carried out with novel composite YH-3 as extraction agent, and the high flux centrifugal extractor was used as extraction device. Under the premise of high phenol extraction rate, composite YH-3 extraction agent reduces n-n interaction between phenolic compounds and aromatic hydrocarbons, thus decreasing the entrainment of neutral oil. The optimization of operation conditions, such as the diameter of heavy phase weir HWD, the flow ratio, the total flow rate and the rotation speed, are necessary. For single stage extraction experiment, the mass transfer efficiency was up to 84% while the rate of extraction agent loss was lower than 0.28% with the operation conditions of 29 mm of the heavy phase weir diameter （HWD）, 1：1-1.4：1 of the flow ratio range, 160-200 mL/min of the total flow rate and the rotation speed varied from 2200 to 2600 r/min. For three stage counter-current test, the mass transfer efficiency reached up to 92.6% with the optimum operation condition of 29 mm of the HWD, 1：1 of the flow ratio, 200 rnL/min of the total flow rate and 2400 r/rain of the rotation speed. The results indicated that phenol could be extracted effectively from coal tar in the process of multistage continuous count current centrifugal extraction.
文摘In this study,extraction of p-cresol from the simulated wastewater has been studied using centrifugal extractors and QH-1 extractant.The distribution ratio of p-cresol was approximately 308.5 in the QH-1-p-cresol(pH=2.0)system.The extraction stage efficiency of the single-stage centrifugal extractor was higher than 92%,and the extraction rate of the three-stage cascade was higher than 99%.When 15% NaOH was used for the stripping of p-cresol in QH-1 solution,the stripping rate of the three-stage cascade reached 100%.A mathematical model of multistage countercurrent extraction process that considers the phase volume change,extraction stage efficiency,and phase entrainment was used to simulate the extraction of p-cresol using centrifugal extractors.The calculated results using this model were in good agreement with the experimental results.
文摘Continuous manufacturing is considered as one of the future trends of pharmaceutical engineering. In this work, continuous liquid-liquid extraction for sinomenine purification was realized with the usage of centrifugal extractors. Chloroform was used as the extractant because of the high distribution coefficient (>100). Higher extraction ratio can be obtained when using the centrifugal extractor of Model CWL50-N. The extraction ratio of the second-stage extraction was higher than that of the first-stage extraction. The extraction ratio of the second-stage countercurrent extraction was higher than that of second-stage cross-flow extraction. When chloroform phase was recycled for liquid-liquid extraction, the extraction ratio was also higher than 95%. This work can also be an example of continuous liquid-liquid extraction for the separation of other Chinese medicine components.
基金the financial support from the National Natural Science Foundation of China(Grant No.22078102)the Shanghai Sailing Program,China(Grant No.21YF1409500).
文摘The annular centrifugal extractor(ACE)integrates mixing and separation.It has been widely used in many industrial fields because of its low residence time,compact structure,and high mass transfer efficiency.Most of the literature has focused on flow instabilities,flow visualization,and computational fluid dynamics simulations.More recently,research on hydrodynamic behavior and structural optimization has received widespread attention.With the development of ACE technology,applications have been broadened into several new areas.Hence,this paper reviews research progress regarding ACE in terms of hydrodynamic characteristics and the structural improvements.The latest applications covering hydrometallurgy,nuclear fuel reprocessing,bio-extraction,catalytic reaction,and wastewater treatment are presented.We also evaluate future work in droplet breakup and coalescence mechanisms,structural improvements specific to different process requirements,scaling-up methods,and stability and reliability after scaling-up.
