Experiences with the Use of Vaginal Dilator by Cervical Cancer Women Who Received Pelvic Radiotherapy at Cancer Diseases Hospital, Lusaka Zambia

Background: Cancer of the cervix is the commonest cancer in women seen at Cancer Diseases Hospital in Zambia and Pelvic Radiotherapy is the main treatment modality used on cervical cancer patients. Radiotherapy to the pelvis has a potential to causes vaginal stenosis but the stenosis can be prevented by regular sexual intercourse or use of vaginal dilators as recommended by cancer organizations. Despite the well-established benefits of vaginal dilators, there was reluctance by women to adopt this practice as seen by the number of survivors with vaginal stenosis at Cancer Diseases Hospital. The objective of this study was to explore experiences with the use of vaginal dilators by cervical cancer women who received Pelvic Radiotherapy. Methodology: A descriptive phenomenological design was used to explore experiences with the use of vaginal dilators by cervical cancer women. The study was conducted at Cancer Diseases Hospital in Lusaka District of Zambia. Participants were identified and purposefully sampled during the follow up clinics, they were then followed for interviews into their homes in Lusaka and data saturation was attained after interviewing 22 participants. Data were analyzed using thematic analysis. Results: Five themes from the study emerged on how women with cervical cancer experienced the use of vaginal dilator;such as uncomfortable dilators, pity for the husband, changed lifestyle, embarrassment and fear. Conclusion: It was acknowledged that the use of vaginal dilator was associated with negative experiences such as uncomfortable dilators, pity for the husband, changed lifestyle, fear and embarrassment. Therefore, this study recommends that Health care providers from CDH and other health institutions should give appropriate information to patients concerning the use of vaginal dilators and the Ministry of Health to provide vaginal dilators instead of 50 milliliter syringes currently in use.

Cervical dilation and improvement of reproductive performance in fat-tailed ewes via cervical dilator treatments

Objective:To determine the effect of different cervical dilators on cervical dilation and reproductive performance of fat-tailed ewes.Methods: In experiment 1140 ewes were divided into seven groups with seven different treatments as following: 10 mL normal saline (control group), 100 IU oxytocin (OT group), 100 μg estradiol and 100 IU oxytocin (E2+OT group), 5 mL relaxin (R group), 2 mL sensiblex (SEN group), 200 μg misoprostol (MIS group) or 200 μg dinoprostone (DIN group). In experiment 2, artificial insemination was applied for evaluation of reproductive performance in experimental groups.Results: In experiment 1, the highest cervical dilation was observed in OT (90%) and E2+OT (100%) groups (P<0.05), while no significant differences was found among DIN, MIS, SEN and R groups (80%, 75%, 70% and 65%, respectively). In addition, the lowest cervical dilation was observed in control group. Experiment 2 found no significant differences among control, OT and E2+OT groups. The highest pregnancy rate, parturition rate and lambing rate were observed in OT groups (60%, 60% and 70%, respectively) and E2+OT groups (65%, 60% and 70%, respectively) compared to SEN, R, MIS and DIN groups (P<0.05).Conclusions:Oxytocin treatment alone or with estradiol could be used as a suitable dilator for improving reproductive efficiency during artificial insemination in fat-tailed ewes.

Changing Trends in Rate of Cervical Dilation in First Stage of Labor: Prospective Longitudinal Study

Introduction: Knowledge of change in the duration of stages of labour would be an essential step to reduce the increasing rates of cesarean section reported worldwide. Objective: To study the rate of cervical dilation in the 1st stage of labour in spontaneous and induced labour and in primigravida and multigravida with singleton pregnancy. Methods: A prospective observational study conducted at a multispeciality hospital was carried out for a period of 3 years from Jan 2017 to Dec 2019. A total of 640 patients who were admitted with spontaneous and induced labour having singleton pregnancy with cephalic presentation and intact membranes after 34 weeks who delivered vaginally were included for analysis. Progression of labor in the 1st stage of labour was measured by the rate of cervical dilation as noted by serial per vaginal examination and findings were plotted in partograph. Result: The difference between mean rate of cervical dilation in the study group is statistically significant between 4 - 6 cm and 6 - 10 cm (P < 0.0001). When primigravida & multigravida patients were compared for the cervical dilation rate, statistically significant difference was seen between 4 - 6 cm but not in 6 - 10 cm. Average rate of cervical dilatation was 3.44 (Standard Deviation (SD) = 1.84) in spontaneous labor while average rate of cervical dilatation was 2.69 (SD = 1.18) in induced labor between 6 - 10 cm of cervical dilatation. Conclusion: The active phase of labour starts at 6 cm of cervical dilation in the majority of the patients. In multigravida, cervix dilates at faster rate before 6 cm. In induced labour cervix dilates at a slower rate than spontaneous labour after 6 cm dilation.

Conservative management of cervical pregnancy: The utility of methotrexate treatment and uterine artery embolization

The aim of this retrospective case series report is to evaluate systemic methotrexate therapy in conjunction with uterine artery embolization (UAE) in the conservative management of cervical pregnancy. We examined clinical presentations, treatments, and therapeutic outcomes in fifteen patients with a cervical pregnancy who wished for preservation of fertility, treated at Okayama University Hospital between 1998 and 2012. Twelve patients received systemic methotrexate including five treated with UAE. One was treated with UAE alone. Two patients received neither UAE nor methotrexate because of a low human chorionic gonadotropin (hCG) level and poor blood flow around the gestational sac (GS). An increased GS size and the elevated hCG level during methotrexate therapy might be risk factors for emergent UAE. Two of six patients treated with UAE had subsequent confirmed viable pregnancies. In patients with a cervical pregnancy, methotrexate therapy in combination with UAE can be considered as an option before performing a hysterectomy with suitable counseling about the risk of loss of fertility. Careful observation of the GS size and hCG level during methotrexate therapy might be important for management.

宫腔镜手术应用Lamiken-R一次性宫颈扩张器效果观察

目的探讨Lamiken-R一次性宫颈扩张器用于宫腔镜手术前扩张松弛宫颈的临床疗效及术前不良反应。方法选择2018年1~6月,诊断为子宫内膜息肉,宫腔粘连,子宫纵膈,子宫黏膜下肌瘤,围绝经期异常子宫出血需要进行宫腔镜检查及电切术的患者共142例,随机分为2组,试验组70例,术前1~2h给予宫颈内口放置Lamiken-R一次性宫颈扩张器;对照组72例,术前2h给予阴道后穹窿处放置卡前列甲酯栓1mg(2枚)。观察试验组Lamiken-R一次性宫颈扩张器置入成功率;2组宫颈扩张效果、术前不良反应及患者满意度。结果试验组70例,成功置入68例,成功率97.1%;不同孕产史患者的宫颈扩张程度比较,试验组已产(顺产)20例患者宫颈扩张器号码(8.01±0.65)大于对照组已产(顺产)25例(6.4±0.73),差异有统计学意义(P<0.05)。试验组已产(剖宫产)28例患者宫颈扩张器号码(7.86±0.86)大于对照组已产(剖宫产)31例(6.51±0.74),差异有统计学意义(P<0.05)。试验组未孕未产22例患者宫颈扩张器号码(7.23±0.65)大于对照组16例(5.87±0.62),差异有统计学意义(P<0.05);2组患者出现腹痛、腹泻、恶心呕吐、阴道流血、发热等不良反应的例数比较,试验组明显低于对照组,差异有统计学意义(P<0.05);试验组总满意度为95.7%,对照组总满意度为58.3%,试验组明显高于对照组,差异有统计学意义(P<0.05)。结论Lamiken-R一次性宫颈扩张器用于宫腔镜手术前扩张宫颈效果显著,术前不良反应少,患者痛苦小,患者满意度高,优于传统的卡前列甲酯栓。

Lamiken-R宫颈扩张器联合米非司酮配伍米索前列醇终止10～16周妊娠的疗效观察

目的探讨Lamiken-R宫颈扩张器联合米非司酮配伍米索前列醇在妊娠10~16周引产中的效果。方法将60例要求引产的妊娠10~16周孕妇按随机数字表法分为观察组及对照组,每组30例。观察组采用Lamiken-R宫颈扩张器联合米非司酮配伍米索前列醇终止妊娠;对照组采用米非司酮配伍米索前列醇终止妊娠。比较2组孕妇的引产时间(用药至胚胎、胎盘娩出时间)、引产效果、出血量及米索前列醇使用量等,观察2组治疗期间不良反应发生情况。结果观察组引产时间及米索前列醇使用量均较对照组显著减少(P<0.05);2组完全流产率及出血量比较差异均无统计学意义(P>0.05)。2组治疗期间无明显药物不良反应。结论 Lamiken-R宫颈扩张器联合米非司酮配伍米索前列醇终止10~16周妊娠的方法较单纯米非司酮配伍米索前列醇缩短了引产时间及降低了米索前列醇使用量,安全有效。

正性暗示语言对宫颈扩张球囊引产孕妇的效果研究

目的探讨正性暗示语言在宫颈扩张球囊引产孕妇中的实施效果。方法选取2023年1月至6月江西省妇幼保健院收治的300例引产孕妇作为研究对象,采用随机数字表法将其分为常规组(150例)和观察组(150例)。对照组采取常规护理,观察组在常规组基础上加用正性暗示语言干预。比较两组孕妇心理状态、舒适度、宫颈成熟程度、妊娠结局和满意度。结果观察组干预后医院焦虑抑郁量表(HADS)评分低于常规组,差异有统计学意义(P<0.05);观察组干预后舒适状况量表(GCQ)评分高于常规组,差异有统计学意义(P<0.05);观察组干预后宫颈Bishop评分高于常规组,差异有统计学意义(P<0.05);观察组自然分娩率为93.33%高于常规组的85.33%,中转剖宫产率为6.67%低于常规组的14.67%,差异有统计学意义(P<0.05);观察组孕妇满意度为96.67%,高于常规组的90.00%,差异有统计学意义(P<0.05)。结论正性暗示语言应用于宫颈扩张球囊引产孕妇中,可促使产妇保持良好心态,增加其身心舒适度,有助于提升宫颈成熟程度,提高自然分娩率,故孕妇对护理服务较为满意。

Uterine artery pseudoaneurysm caused by hysteroscopic surgery: A case report

BACKGROUND We report a case of uterine artery pseudoaneurysm(UAP)occurrence during hysteroscopic endometrial polypectomy and its treatment via uterine artery embolization(UAE).CASE SUMMARY A 48-year-old primigravid,primiparous patient was incidentally found to have an endometrial polyp during a health checkup,and underwent a hysteroscopic polypectomy at another hospital.Her cervix was dilated with a Laminken-R®device.After the Laminken-R®was withdrawn,a large amount of genital bleeding was observed.This bleeding persisted after the hysteroscopic polypectomy,and,as hemostasis became impossible,the patient was transferred to our hospital by ambulance.On arrival,transvaginal ultrasonography revealed a 3-cm hypoechoic mass with a swirling internal pulse on the right side of the uterus,and color Doppler ultrasonography showed feeder vessels penetrating the mass.Pelvic contrast-enhanced computed tomography(CT)confirmed the presence of a mass at this site,and vascular proliferation was observed within the uterine cavity.Consequently,UAP was diagnosed,and UAE was performed.The patient’s postoperative course was uneventful,and 6 mo post-UAE,no recurrence of blood flow to the UAP was observed.CONCLUSION When abnormal genital bleeding occurs during hysteroscopic surgery,ultrasonography and contrast-enhanced CT can assist in the detection of early UAPs.

宫颈癌放疗病人阴道扩张康复措施证据总结

目的:检索、总结并评价宫颈癌放疗病人阴道扩张的相关证据,为临床实施阴道扩张提供证据。方法:按照循证资源“6S”模型,系统检索国内外数据库、指南网及专业协会网站,收集宫颈癌放疗病人阴道扩张相关文献,检索时限为建库至2023年1月15日。结果:共纳入14篇文献,包括2篇专家共识、3篇临床实践、2篇指南、4篇系统评价、3篇随机对照研究,最终从目标人群、扩张准备、扩张时机、扩张频率、注意事项、性健康指导、随访管理与支持7个方面总结出25条证据。结论:总结的宫颈癌放疗病人阴道扩张康复措施的最佳证据具有科学性及实用性,可为医护人员对宫颈癌放疗病人的阴道康复提供循证依据。

子宫颈扩张球囊对妊娠晚期引产促宫颈成熟的临床疗效及安全性观察

目的探讨妊娠晚期足月引产产妇应用子宫颈扩张球囊促宫颈成熟的临床疗效与安全性。方法选取2019年5月至2020年5月于吉安市妇幼保健院分娩的100名足月妊娠引产产妇作为研究对象,按照随机信封法分为对照组与实验组,每组50名。对照组应用催产素引产,实验组应用子宫颈扩张球囊引产。比较两组引产成功率、促宫颈成熟优良率、产程、产后出血量、母婴结局、新生儿出生质量。结果实验组引产成功率、促宫颈成熟优良率均高于对照组,差异有统计学意义(P<0.05)。实验组第一、第二产程及总产程均短于对照组,产后2h出血量少于对照组,差异有统计学意义(P<0.05)。实验组胎儿宫内窘迫、胎盘早期剥离、产褥感染发生率及剖宫产率均低于对照组,差异有统计学意义(P<0.05)。两组新生儿出生后1、5min的Apgar评分比较差异无统计学意义。结论妊娠晚期足月引产产妇应用子宫颈扩张球囊促宫颈成熟的有效性、安全性更高,值得临床推广应用。

瘢痕子宫妊娠中期引产方法的研究

目的 观察应用宫颈扩张球囊联合乳酸依沙吖啶注射液对瘢痕子宫妊娠患者中期引产的效果及对患者产后心理的影响。方法 选取2022年1月至2023年12月在我院就诊的瘢痕子宫妊娠中期引产患者128例,随机分为观察组和对照组,每组64例。对照组患者采用传统的米非司酮150 mg口服+乳酸依沙吖啶注射液100 mg羊膜腔内注射引产;观察组患者采用COOK宫颈扩张球囊促宫颈成熟+米非司酮150 mg口服+乳酸依沙吖啶注射液50 mg羊膜腔内注射引产。对比2组患者的引产总时间、产程总时间、产后出血量、引产总有效率、软产道裂伤发生率、先兆子宫破裂发生率及产后心理状况。结果 观察组患者的总有效率高于对照组,引产总时间及产程总时间短于对照组,产后出血量少于对照组,差异均有统计学意义(P<0.05)。2组患者并发症发生率比较,差异无统计学意义(P>0.05)。对照组爱丁堡产后抑郁量表(EPDS)阳性患者比例明显高于观察组(t=10.818,P<0.05),2组患者在EPDS中的10个情绪方面比较,差异有统计学意义(P<0.05)。结论 对于瘢痕子宫妊娠中期患者,使用COOK宫颈扩张球囊促宫颈成熟+米非司酮150 mg口服+50 mg乳酸依沙吖啶注射液羊膜腔内注射引产的效果良好,有利于产妇产后心理健康。

宫腔镜术前宫颈软化的临床研究

目的比较宫腔镜术前应用间苯三酚注射液、米索前列醇、一次性宫颈扩张用模具软化宫颈的效果及不良反应。方法选择2020年7月至2022年12月在该院进行宫腔镜手术的150例患者为研究对象,按照随机数字表法分为间苯三酚组(A组)、米索前列醇组(B组)、一次性宫颈扩张用模具组(C组),每组50例。比较3组患者宫颈软化效果、扩宫时间、术中漏水率及不良反应发生率。结果3组患者宫颈软化有效率比较,差异均有统计学意义(P=0.023),A组宫颈软化有效率明显高于B组(P=0.012),C组宫颈软化有效率虽高于B组,但差异无统计学意义(P=0.053)。3组患者扩宫时间比较,差异有统计学意义(P=0.018),A组和C组扩宫时间均短于B组,差异有统计学意义(P=0.008、0.031),A组和C组扩宫时间比较,差异无统计学意义(P=0.600)。3组患者术中漏水率比较,差异无统计学意义(P=0.108)。3组患者不良反应发生率比较,差异有统计学意义(P<0.001)。B组不良反应发生率最高,均明显高于A组与C组(P<0.001、0.011)。结论3种宫颈扩张方法各有利弊,宫腔镜术前需结合手术时间、漏水率、医疗成本、不良反应等综合考虑,选择软化宫颈的方式。

宫颈扩张球囊联合缩宫素在足月孕妇引产中的应用效果及对不良妊娠结局的影响

目的:探讨宫颈扩张球囊联合缩宫素在足月孕妇引产中的应用效果及对不良妊娠结局的影响。方法:选取2019年1月—2024年1月广东医科大学顺德妇女儿童医院收治的足月孕妇95例,按照随机数字表法分为两组,其中对照组(n=47)采用缩宫素治疗,观察组(n=48)采用宫颈扩张球囊联合缩宫素治疗。记录并比较两组引产成功率,宫颈成熟度评分,引产成功者产程时间及不良妊娠结局发生率。结果:观察组引产成功率(77.08%)高于对照组(55.32%),差异有统计学意义(P<0.05)。治疗12 h,观察组Bishop评分高于对照组(P<0.05)。观察组中引产成功者各产程时间均短于对照组中引产成功者(P<0.05)。观察组不良妊娠结局发生率(8.33%)低于对照组(25.53%),差异有统计学意义(P<0.05)。结论:宫颈扩张球囊联合缩宫素能提高足月孕妇引产成功率,促进子宫颈成熟并能缩短产程,且能降低不良妊娠结局发生率。

宫颈扩张棒与卡前列甲酯栓对宫颈手术史绝经后妇女取环成功率及宫颈软化度的影响

目的:分析宫颈扩张棒与卡前列甲酯栓在宫颈手术史绝经后妇女中的效果。方法:选取2020年4月至2022年4月于峄城区妇幼保健计划生育服务中心择期行取环术的有宫颈手术史的绝经后妇女68例,按随机数字表法分为两组,各34例。对照组予以宫颈扩张棒,观察组给予卡前列甲酯栓。对比两组一次性取环成功率、术后30min疼痛程度、宫颈软化度。结果:观察组一次性取环成功率[94.12%(32/34)]高于对照组[76.47%(26/34)],术后30min的视觉模拟疼痛量表(VAS)评分[(2.05±0.31)分]低于对照组[(2.67±0.45)分],宫颈软化度[94.12%(32/34)]优于对照组[76.47%(26/34)],有统计学差异(P<0.05)。结论:与宫颈扩张棒相比,卡前列甲酯栓在宫颈手术史绝经后妇女取环术中效果更为显著,可更有效地降低术后疼痛,提高宫颈软化度,获得优良的一次性取环成功率,安全可靠。

子宫颈扩张球囊应用于妊娠晚期女性宫颈成熟和引产的优势评价

目的 评价子宫颈扩张球囊应用于妊娠晚期女性宫颈成熟和引产的优势。方法 方便选取2022年12月—2023年12月武汉真爱妇产医院妇产科引产的62例妊娠晚期产妇,使用随机数字表法分为对照组和研究组,每组31例。对照组患者行缩宫素引产,研究组患者在此基础上行子宫颈扩张球囊引产,对比两组患者的宫颈成熟和引产情况。结果 研究组患者促宫颈成熟有效率(96.77%)高于对照组(80.65%),差异有统计学意义(P<0.05)。研究组患者第一产程时间(7.23±1.67)h、第二产程时间(0.56±0.18)h及总产程时间(8.49±1.35)h短于对照组,产后出血量(210.85±34.41)mL少于对照组,差异有统计学意义(P均<0.05)。研究组患者母婴不良结局总发生率低于对照组,差异有统计学意义(P<0.05)。两组患者并发症总发生率对比,差异无统计学意义(P>0.05)。结论 妊娠晚期应用子宫颈扩张球囊可促进宫颈成熟,提高阴道分娩率,改善母婴结局。

地诺前列酮与宫颈扩张球囊用于足月产妇促宫颈成熟及引产的可行性及安全性分析

目的探讨地诺前列酮与宫颈扩张球囊用于足月产妇促宫颈成熟及引产的可行性及安全性。方法选取2020年1月至2023年3月在徐州医科大学附属徐州市立医院住院分娩的足月产妇80例为研究主体进行前瞻性研究,根据其住院ID号将其分至两组中,即地诺前列酮组与球囊组。地诺前列酮组年龄(28.67±2.17)岁;初产妇30例,经产妇10例;孕周37~41(39.12±1.23)周;采用地诺前列酮栓促宫颈成熟。球囊组年龄(28.44±2.12)岁;初产妇31例,经产妇9例;孕周37~42(39.23±1.19)周;采用宫颈扩张球囊促宫颈成熟。比较两组宫颈Bishop评分、促宫颈成熟效果、分娩情况、不良反应发生情况、引产结局。采用独立样本t检验和χ^(2)检验。结果地诺前列酮组引产后Bishop评分为(8.58±0.51)分,与球囊组(8.62±0.58)分比较,差异无统计学意义(t=0.328,P=0.744);地诺前列酮组总有效率92.50%(37/40),与球囊组95.00%(38/40)比较,差异无统计学意义(χ^(2)=0.213,P=0.644);地诺前列酮组干预至临产时间、第一产程、总产程及干预至阴道分娩时间分别为(14.68±3.81)h、(5.67±2.23)h、(6.12±2.24)h及(34.21±5.49)h,均短于球囊组的(20.22±4.26)h、(7.23±1.12)h、(8.02±1.22)h及(45.25±6.58)h(t=6.131、3.954、4.711、8.148,均P<0.001);球囊组胎膜早破及宫缩过频发生率分别为2.50%(1/40)及0,低于地诺前列酮组的22.50%(9/40)及25.00%(10/40)(χ^(2)=7.314、11.429,均P<0.05);地诺前列酮组与球囊组引产结局比较,差异均无统计学意义(均P>0.05)。结论对于足月分娩的产妇,选择宫颈扩张球囊或地诺前列酮促宫颈成熟及引产都是安全有效的,然而采用地诺前列酮可缩短产妇的临产时间和总产程,适用于需要缩短产程的高危产妇,但其易导致子宫过度刺激及血压波动大,导致产妇宫缩过频、胎膜早破,因此,要根据个体病例选择适宜的方式。

初产妇和经产妇应用子宫颈扩张双球囊引产的结局比较

目的:探讨初产妇和经产妇应用子宫颈扩张双球囊引产的结局。方法:回顾性选取2021年1月—2023年9月郎溪县人民医院接受子宫颈扩张双球囊引产的150例产妇,根据产次分为初产妇组和经产妇组,各75例。比较两组球囊放置到分娩时间、球囊放置前后宫颈Bishop评分、促宫颈成熟有效率、引产效果及新生儿结局。结果:球囊放置后,经产妇组宫颈Bishop评分高于初产妇组,差异有统计学意义(P<0.05);经产妇组球囊放置到分娩时间短于初产妇组,促宫颈成熟总有效率高于初产妇组,差异有统计学意义(P<0.05)。经产妇组剖宫产、阴道助产、继发感染、分娩镇痛、发热的发生率均低于初产妇组,差异有统计学意义(P<0.05)。经产妇组新生儿产伤、新生儿窒息率低于初产妇组,差异有统计学意义(P<0.05)。结论:相比于初产妇,经产妇使用子宫颈扩张双球囊引产的效果更好,且副作用较少。初产妇需寻找更有效地促进宫颈成熟方法,以减少剖宫产率和母婴不良结局。

宫颈扩张球囊联合缩宫素对足月妊娠引产产妇宫颈成熟及母婴结局的影响

目的探讨宫颈扩张球囊与缩宫素联用对足月妊娠引产产妇宫颈成熟及母婴结局的影响。方法选择2021年6月至2022年12月我院130例足月妊娠引产产妇,根据随机数字表法将所有产妇两组,每组65例。对照组采用缩宫素进行引产,观察组联合宫颈扩张球囊进行引产。对比两组宫颈成熟情况、分娩情况、应激反应、引产期间并发症情况、母婴不良结局。结果比较两组宫颈成熟情况,观察组Bishop宫颈成熟度评分(9.13±0.36)分、促宫颈成熟总有效率为(95.38%),比对照组的(7.61±0.32)分、83.08%高,差异有统计学意义(P<0.05);比较两组分娩情况,观察组临产时间(14.28±2.19)h、总产程时间(6.18±1.13)h短于对照组的(18.37±2.62)h、(8.65±1.56)h,产后出血量(206.47±8.52)m L少于对照组(223.45±10.72)m L,引产成功率(95.38%)高于对照组(83.08%),剖宫产率(4.62%)低于对照组(16.92%),差异有统计学意义(P<0.05);比较两组生产前应激反应,差异无统计学意义(P>0.05);观察组生产后皮质醇(Cor)(53.66±2.84)ng/L、儿茶酚胺(CA)(249.37±7.51)ng/L、谷氨酸(GLU)(5.56±0.58)mmol/L水平均低于对照组的(69.78±3.12)ng/L、(326.45±10.61)ng/L、(7.27±0.89)mmol/L,差异有统计学意义(P<0.05);观察组引产期间并发症发生率(6.16%)低于对照组(18.46%),差异有统计学意义(P<0.05);观察组母婴不良结局发生率(7.70%)低于对照组(23.10%),差异有统计学意义(P<0.05)。结论宫颈扩张球囊与缩宫素联合作用,可显著加快足月妊娠产妇宫颈成熟度,改善母婴结局,值得临床借鉴。

宫颈扩张球囊联合缩宫素在足月妊娠引产中的应用效果

目的:观察宫颈扩张球囊联合缩宫素在足月妊娠引产中的应用效果。方法:回顾性分析2022年3月至2023年3月该院收治的84例足月妊娠引产产妇的临床资料,按照引产方法不同将其分为观察组和对照组各42例。对照组采用缩宫素引产,观察组在对照组基础上联合宫颈扩张球囊引产。比较两组促宫颈成熟效果、临产开始时间、总产程时间、分娩方式和并发症发生率。结果:观察组促宫颈成熟总有效率为92.86%(39/42),高于对照组的73.81%(31/42),差异有统计学意义(P<0.05);观察组临产开始时间、总产程时间均短于对照组,差异有统计学意义(P<0.05);观察组自然分娩率高于对照组,剖宫产率低于对照组,差异均有统计学意义(P<0.05);观察组并发症发生率为7.14%(3/42),低于对照组的26.19%(11/42),差异有统计学意义(P<0.05)。结论:宫颈扩张球囊联合缩宫素应用于足月妊娠引产中可提高促宫颈成熟总有效率,缩短临产开始时间和总产程时间,改善分娩方式,降低并发症发生率,效果优于单纯缩宫素引产。

探讨米索前列醇在妊娠早期人工流产中的应用方法及价值评价

目的探讨米索前列醇在妊娠早期人工流产中的应用价值。方法选取62例行人工流产手术的妊娠早期孕妇,根据随机抽签法分为对照组(采用常规手术)与研究组(采用米索前列醇),每组31例。比较两组不良反应发生率,宫颈扩张效果及临床指标。结果研究组的不良反应发生率为3.23%,对照组不良反应发生率为25.81%,比较差异有统计学意义(P<0.05)。研究组宫颈扩张有效率高于对照组(P<0.05)。研究组术中出血量少于对照组,手术时间短于对照组,且宫缩幅度大于对照组(P<0.05)。结论妊娠早期人工流产孕妇采用米索前列醇,能增强宫缩扩张力,同时具备时效性强及安全可靠价值,值得临床推广。