基于旅游价值链模型的旅游业态团化进程及模式探究——以华侨城为例

高质量发展是中国式现代化的本质要求。旅游业态团化作为产业高质量供给的一种体现,其研究具有重要意义。文章界定旅游业态团化概念,对华侨城旅游事业发展历程展开案例研究,凝练出旅游业态团化路径图,为产业及企业发展提供启示。研究发现:1)以旅游价值链为基础的旅游业态团化进程分为线型无核、线型单核和树型多核3阶段,3阶段旅游业态是由点到组、由组到团的演进过程;2)旅游业态团化模式有环节渗透式、链条重组式和网状重构式,3种模式是旅游产业从内部融合到跨界融合再到叠式融合的递进过程;3)旅游业态团化过程表征着产业大融合,揭示了产业纵横交错、深度融合的路径和方式。

Forming process chain for manufacturing complex conical-section profiled rings:On a co-design method

The final quality of complex conical-section rings depends on co-design of multiple processes in forming process chain.In this study,for a complex aeroengine casing ring with a large slope and a flange on its end,a co-design method of the forming process chain is put forward towards the objective of precision forming,which not only proposes a standard process route composed of multiple processes of upsetting,punching,rectangular ring rolling,loose tooling forging and profiled ring rolling,but also presents co-design methods of dies and blanks for all the processes.For profiled ring rolling,a design method of preformed blank that makes the blank and the target conical-section ring have the same axial volume distribution is proposed.By the method,the axial metal redistribution during the process can be alleviated greatly thus improving the forming stability and precision of the ring.Based on the geometric features of designed preformed blank,design methods of blanks and dies for loose tolling forging,rectangular ring rolling,punching and upsetting are proposed sequentially.In view of the key roles of loose tooling forging(manufacturing the preformed blank)and profiled ring rolling on the final quality of the conical ring parts,inherited FE simulations for these two processes are performed to verify the proposed design methods and determine appropriate design parameter.It is demonstrated that the proposed design method has significant advantages in improving forming precision.Besides,a suggestive value 1.5 of the rolling ratio for profiled ring rolling(a key design parameter)is given based on comprehensive consideration of multiple indicators such as ring roundness,deformation uniformity and forming load.The corresponding industrial experiments performed illustrate that a high forming precision of the conical-section aeroengine casing ring is achieved.

边双链刮板结构设计研究

边双链刮板输送机链条布置在刮板的两端,刮板链运转过程中主要承受两端链条的牵引力和输送物料产生的阻力,物料产生的阻力主要集中在刮板上,刮板链运行过程中刮板受力近似为简支梁结构,不同于中双链刮板工作时的受力状态,边双链刮板的设计要充分考虑其工作特性,在不显著增加刮板质量的同时提高刮板抗弯强度。

传统村落文化景观基因信息链的提取与空间特征研究——以张谷英村为例

传统村落作为我国文化遗产的重要组成部分,积淀着中国传统民族精神和中国智慧。现有传统村落文化景观的形态研究,尚未从整体视角系统分析文化景观基因信息链的空间形态特征。本文以张谷英村为例,结合文化景观基因信息链,运用形态特征基本分析模式探究信息链的空间形态特征,分析空间组织规律和影响因素。结果表明:①张谷英村文化景观基因信息链空间形态特征的基本类型有等级型、文脉型和风水型。等级型的民居信息链依宗族礼制的秩序演化,呈中轴对称、主次分明的“丰”字形;文脉型的耕读信息链以耕读文化为脉络隐性发育,呈线性模糊、散点分布的串珠形;风水型的龙形风水信息链是在山水环境和风水文化的共同作用下,呈虚实相间、巨龙戏珠的树枝形。②三类信息链都彰显了联通性、有序性、向心性和韵律性的空间组织规律。③信息链的发育和形成主要受自然山水、宗族血缘、儒家礼制和风水思想四个方面的影响。

基于SEI-ET的高等院校双创人才培养模式探索与实践

当前我国高等教育在培养具有初创能力的创业实践团队方面还存在一定短板,无法打造可直接服务于国民经济与行业发展的初创团队。基于此,本文介绍了基于SEI-ET的双创人才培养模式,并分别从培养理念、培养方案、配套课程与积分体系、考核机制、师资力量与创业氛围6个方面进行探索实践并提出合理化建议。最后得出基于SEI-ET的双创人才培养模式有利于我国综合性大学培养更多直接服务于国民经济与行业发展的创业实践团队。

Agent Architecture and Collaboration for Supply Chain Management

Recently multi-agent system(MAS)is regarded as a powerful paradigm to develop and simulate complex system. Because supply chain(SC)is a complex network,it is hard to improve supply chain management(SCM)efficiency and automate SC operating process.Researchers have applied MAS in SCM viewing enterprises in SC as different functional agents collaborating to achieve common goal.In this paper a MAS-based supply chain management framework(MSF)is developed on which agents can collaborate to conduct business activities of enterprises and customers.Six kinds of functional agents are designed,namely, management agent,order receiving agent,order decomposing agent,resource agent,manufacturing-controlling agent and trans- portation agent.Through the agents’ collaboration the MSF can support SC dynamic forming and operating process.For partner selection the method to transmit customers’ order into demand matrix,and transmit enterprise’s resource capacity into resource matrix is described in detail.The MSF users decide which algorithm to be applied in matching the two matrixes,and algorithms are stored in model base.Finally the generic agent architecture is put formard.

基于扇形非均匀电场的水滴成链及碰撞实验

为研究高压方波脉冲电场内油包水乳液中水滴的成链及碰撞特性,基于水滴极化运动理论,并采用扇形非均匀电场进行显微实验。结果表明:水滴成链速度随电压单调递增,但电压过大会加剧链上水滴的聚结,而破坏水滴排列影响成链速度;成链速度随频率的增加先增大后减小,当频率为300 Hz时有极大值0.251 5μm/s。小水滴向大水滴运动并发生碰撞,而尺寸相近的水滴做相向运动;塑性碰撞发生后,小水滴液膜破裂并融入到大水滴中聚结为一个水滴,且增大电压和减小频率,聚结行为显著增强。频率对碰撞速度的影响最大,其次是体积差和电压。得到了电压、频率和体积差对水滴极化后运动的影响规律,为电破乳器的研制提供借鉴。

Application of PCR-SSCP in detecting rpoB drug resistant gene polymorphism of M. tuberculosis L-form from pneumoconiosis patients with tuberculosis

Objective: To study the relationship between the polymorphism of drug resistant gene rpoB and drug resistance against rifampicin(RFP) of M. tuberculosis L-forms, and to evaluate its clinical application. Methods: A total of 52 clinical isolated strains of M. tuberculosis L-forms were collected. rpoB gene polymorphism was analyzed by polymerase chain reaction and single-strand conformation polymorphism (PCR-SSCP) and conventional antimicrobial susceptibility test (AST). Their results were compared. Results: AST results showed that 38 of 52 clinical isolated strains were drug resistance (73.08％),while PCR-SSCP indicated 65.38％ (32/52) rpoB gene polymorphism. There was no statistic significance(χ2= 2.4914) between the 2 methods. Conclusion:Combined the application of PCR-SSCP with AST in detecting rpoB drug resistant gene polymorphism of M. tuberculosis L-form from pneumoconiosis patients with tuberculosis may have advantages at earlier diagnosis and guidance of clinical medications.

Hierarchy of mesenchymal stem cells: Comparison of multipotentmesenchymal stromal cells with fibroblast colony forming units

The organization of the compartment of mesenchymal stem cells is still obscure. Two types of human stromal precursor cells are known. Both of them are analyzed in in vitro system: mesenchymal multipotent stromal cells (MMSC) and fibroblast colony forming units (CFU-F). The aim of this study was to compare the main characteristics of MMSC and CFU-F derived from the bone marrow of 24 healthy donors. Growth and differentiation parameters, as well as relative expression levels of different genes were analyzed in MMSC and CFU-F. MMSC were cultivated for 5 passages. CFU-F concentration was determined for each bone marrow sample. The data obtained demonstrated the heterogeneity and hierarchical organization of both studied populations of stromal precursor cells-MMSC and CFU-F. These two types of stromal precursor cells turned to be different in most parameters studied. Altogether MMSC seemed to be more immature cells than CFU-F and took up the higher position in hierarchical tree of mesenchymal stem cells. The rate of differentiation and proliferative potential decreased with the donor’s age in both populations MMSC and CFU-F.

帽形件链模成形坯料线预示方法

针对链模成形工艺的特点,基于一步逆成形法提出了帽形件链模成形坯料线预示方法,该方法分析了帽形件成形前后的几何关系、计算了链模成形力和纵向拉力,并将纵向拉力等效到帽形件端面边界上,然后基于虚功原理建立了内外力平衡方程,根据线弹性反向变形理论获得了帽形件链模成形坯料线预示算法的迭代初始解,最后使用Newton-Raphson迭代法求解方程获得了帽形件坯料线。对某一车型梁形件的链模成形进行了有限元仿真与试验,验证了帽形件链模成形坯料线预示方法的准确性。

Detecting drug resistant genetic mutation among pneumoconiosis patients complicated with tuberculosis in Mycobacterium tuberculosis L-forms application of PCR-SSCP technique in Huainan mining district

Objective： To study the relationship between drug resistant genetic mutation and drug resistance in Mycobacterium tuberculosis L-form, discuss the internal relationship between drug resistances and drug-resistant related genes and explore the value of PCR- SSCP to clinical application. Methods： A total of 52 clinically isolated strains of tuberculosis L-form were collected among 97 pneumoconiosis patients complicated with tuberculosis. The gene mutations of katG, rpoB and rpsL were detected by PCR-SSCP, and the results were compared with those analyzed by traditional antimicrobial susceptibility test（AST）. Results： The gene muta- tion rates of katG, rpoB and rpsL by PCR-SSCP were respectively 57.70% （30/52）, 65.38% （32/52） and 40.38% （21/52）. The rate of reversion was 78.85%（41/52） and the result of drag-resistant genes was invariable. The results of AST showed that there were 40 （76.92%） multi-drug resistant strains in 52 clinically isolated strains. The number for three-drug resistant strain was 21 （40.38%） and that of two-drug resistant was 19（36.54%）, but only 12（23.08%） strains were one drug resistant. The rate of total drug-resistance was 100%, but there were 15 strains of allied mutation of three genes, 16 of two mutations and 6 of only one by PCR-SSCP. The coincidences were respectively 71.43%, 84.12% and 50.00%. Then there was no significant difference between the allied mutations of multi-drug resistant gene and the mutations of only one drug resistant gene （P 〉 0.05）. Conclusion： PCR-SSCP technique has a higher sensibility and specificity to detect the genes of katG, rpoB and rpsL in tuberculosis L-form among pneumoconiosis complicated with tuberculosis,and the detecting rate of two drug resistant strains and three drug resistant strains was higher. The combined application of PCR-SSCP and AST has advantages at earlier diagnosis and guidance of clinical medications.

芒针深刺联合穴位贴敷治疗卒中后排便障碍的效果及对肠道SCFAs的影响

目的 探讨芒针深刺联合穴位贴敷治疗卒中后排便障碍的临床效果,观察对肠道短链脂肪酸(short chain fatty acids,SCFAs)含量的影响。方法 选择秦皇岛市中医医院2020年8月至2022年2月收治的卒中后排便障碍患者,随机分为研究组和对照组,对照组(43例)接受脑卒中的常规治疗和神阙穴穴位贴敷,研究组(43例)在对照组的基础上接受芒针深刺治疗,疗程均为4周。比较两组治疗前后临床症状评分(包括排便困难、排便时间、排便频率和腹胀评分)、Bristol粪便性状量表(bristol stool form scale,BSFS)评分、慢性便秘严重度评分量表(chronic constipation severity rating scale, CCS)评分、直肠肛管容量感觉阈值[包括直肠扩张时初始感觉阈值(first sensation volume, FSV)、初始排便阈值(defecating sensation volume, DSV)和最大耐受阈值(maximum tolerable volume, MTV)]、粪便SCFAs含量,并比较两组治疗总有效率。结果 治疗后,两组临床症状评分(包括排便困难、排便时间、排便频率、腹胀评分)、CCS评分、FSV、DSV、MTV均降低(P<0.01),BSFS评分、粪便中丁酸和SCFAs含量均升高(P<0.01);研究组临床症状评分、CCS评分、FSV、DSV、MTV均低于对照组(P<0.01),BSFS评分、粪便中丁酸和SCFAs含量均高于对照组(P<0.01);研究组治疗总有效率高于对照组(P<0.01)。结论 芒针深刺联合穴位贴敷可有效缓解临床症状,增加肠道SCFAs含量,改善粪便性状,降低排便障碍程度,治疗卒中后排便障碍效果显著。

海南不同地区红火蚁社会型鉴定

为明确海南部分地区红火蚁的社会型,通过多重PCR(Multiplex Polymerase Chain Reaction)技术及Gp-9^(b)等位基因扩增2种方法,鉴定分析了采集自海南万宁、琼海、海口、陵水、文昌、屯昌和儋州7个不同地区的红火蚁的社会型。鉴定结果表明,采自7个地区的不同蚁巢社会型均为多蚁后型。本研究对海南地区科学监测红火蚁具有重大意义,同时为增强红火蚁的防治效果提供理论依据。

中药材百年发展历程与供应链的关系及启示

我国中药材供应链的发展可以分为四个阶段:从新民主主义革命时期的萌芽,到计划经济时期的曲折发展,到改革开放后的快速发展,再到党的十八大以来的提质增效,百年来中药材供应链呈现出鲜明的规律特征。一百年来,中药材供应链由量变走向质变,中药材供应链形态不断完善,现代中药材供应链逐渐成形且不断优化。中药材供应链百年发展历程取得了巨大的成就,并积累了丰富且宝贵的经验:坚持党的领导是发展中药材供应链的基本前提;政策支持是促进中药材供应链发展的重要驱动力;注重科技创新是中药材供应链发展的内生动力;充分发挥龙头企业在中药材供应链发展中的引领带动作用。这些经验为持续推动中药材供应链高质量发展提供了重要借鉴和启示。

轿车底盘整体合装成功概率计算与误差分布模型

底盘盒装是整车装配关键环节,合装部件的形位公差决定合装成功率和成本。文章首先描述了合装误差概率的物理模型,然后运用尺寸链理论将其抽象为一个适当简化的合装数学模型,对合装成功率进行了公式推导和概率计算。最终在相关工装设备的公差、精度要求条件下得出理论上99.986%的成功概率,相比于实际值较大,经分析考虑到模型经适度简化且有假设条件此差异符合预期。该模型已广泛运用于多条标准化多平台汽车混合装配线。

供应链的产业经济属性及其发展趋势

我国相关国家标准将供应链界定为“供需链状网”和“网链结构”,随着经济全球化步伐加快、现代科技的迅猛发展、产业分工日益精细化、各类资本的参与以及产业经济理论的不断进步,供应链的新型业态不断涌现,已经呈现出高度的组织化产业特征。目前,以美国为主要代表的西方发达国家已经从整体上将全球供应链安全上升至国家战略高度,这对我国具有重要的启发意义。有必要从产业经济学角度对供应链的产业属性和价值、供应链产业形成的时代条件,以及供应链产业的新发展趋势等内容进行研究,以深入理解供应链的产业经济属性,掌握供应链的发展规律,为切实提升供应链的韧性和安全水平,更好适应全球供应链的竞争与合作提供理论支撑。

磺酸钠两性型表面活性剂聚集体形态的研究

为研究疏水碳链长度和浓度对两性型表面活性剂聚集行为的影响,以具有不同疏水碳链长度的磺酸盐两性型表面活性剂作为研究对象,借助动态光散射技术(DLS)测定了疏水碳链长度(m)分别为12,14,16,18的产品在浓度分别为2CMC、10CMC、50CMC的聚集体形态。以光强与流体力学半径的关系分析可知,聚集体的形态随着浓度升高更趋向于形成粒径较大的聚集体,随着疏水碳链长度的增加,聚集体的形态也基本趋向于小粒径分布。

计算机网络的组网形式与设备配置分析

阐述计算机网络组网形式中的路由网络、交换网络、共享网络,探讨计算机网络设备配置技术,包括网域地址设置、逻辑链设置、私有网络设置。

基于有限元方法的车身B柱全工序焊接变形研究及应用

为研究不同车身结构对焊接变形的影响,对欧版原型车和产品安全措施(product safety measure,PSM)项目车型的B柱区域同时建立电阻焊有限元焊接模型。应用热弹塑性有限元方法模拟B柱区域的焊接变形量,并进行B柱区域全工序链式仿真,得到整体焊接变形量。结果表明,B柱区域在电阻焊后产生最大0.85 mm的变形,与实际变形量0.90 mm吻合。利用全工序链式仿真获得的整体变形量比各个工序简单累加的结果小,实际应用中效果良好。

矿业开发环境地质链及其控制

从环境地质问题形成机制入手 ,研究矿业开发环境地质链的形成及结构 ,进而探讨矿业开发环境地质链时空特征以及环境地质链的控制思想和原则。最后以平顶山矿区矿业开发环境地质链控制为实例 ,阐述矿业开发环境地质链的控制方法和模型 ,在一定程度上为今后利用环境地质链控制的新方法和新思想解决矿山环境地质问题、实现矿业开发的可持续发展提供了理论和实践依据。