Mechanism of traditional Chinese medicine in the treatment of psoriasis with depression:A review

Psoriasis is a kind of immune-mediated, chronic, inflammatory skin disease, which is often associated with different degrees of psychological disorders. Specifically, there is a significant correlation between psoriasis and depression, and they show the relationships of reciprocal causation and mutual promotion. Psoriasis with depression is more harmful than simple psoriasis, and its prognosis is worse, which brings a huge burden to the family and society and is worthy of clinical attention. Based on the pathogenic factors of western medicine and pathogenesis of traditional Chinese medicine in psoriasis with depression, the paper summarized and elaborated the research progress on the mechanism of traditional Chinese medicine in the treatment of psoriasis with depression, in order to provide new ideas for clinical treatment.

Application and Practice of Traditional Chinese Medicine Characteristic Technology Inheritance in Research and Development of Traditional Chinese Medicine Preparations in Medical Institutions

Medical institution preparations play an important role in the development of hospitals,being one of the main forms of traditional Chinese medicine clinical characteristic medication,as well as an important carrier for the inheritance and innovation of traditional Chinese medicine.In recent years,the research and development of traditional Chinese medicine preparations has become a hot spot in the research and development of preparations by medical institutions.Traditional Chinese medicine preparations prepared by traditional processes and their entrusted preparation matters have changed from the current licensing management to filing management.The registration model of traditional Chinese medicine preparations has undergone significant changes,emphasizing more on real data and evaluation results from the objective world,respecting traditional medication experience,and emphasizing the inheritance and innovative development of traditional technological experience.In the process of following teachers in the inheritance project of traditional Chinese medicine,we combined the inheritance of traditional Chinese medicine characteristic technology with the research and development practice of traditional Chinese medicine preparations in medical institutions,and focused on the analysis and discussion of technical problems such as prescription screening,dosage form selection,process route design and clinical observation of traditional Chinese medicine preparations,hoping to provide reference for scholars in the same field of traditional Chinese medicine.

Through a Century: Traditional Chinese Medicine Since 1912

Since 1912,traditional Chinese medicine(TCM)went through the stages of the struggle,foundation,and growth.The all-round developing TCM is academically progressing and promoted worldwide.Characteristics of the centennial development of TCM have cultural relevance,policy pertinency,mutual supplement between Chinese and western medicine and TCM is treatment directed by pattern diagnosis.Researches show that the historical inevitable development of TCM will benefit the people for generations to come when taken as a national strategy.

Unique Traditional Chinese Medicine Therapy for Painful Diabetic Peripheral Neuropathy

Painful diabetic peripheral neuropathy is one of the common chronic complications of diabetes."Pain"is the most typical symptom in patients,which seriously affects their quality of life.Traditional Chinese medicine(TCM)treatment of the disease includes oral administration of Chinese medicine,TCM fumigation and acupuncture,etc.,which can significantly reduce the pain of patients and reduce the frequency of disease.Chinese decoctions regulate the imbalance of yin and yang in the human body through syndrome differentiation,so as to achieve the balance of yin and yang,which will then eliminate the disease.Chinese medicine fumigation make the medicine seep into the body from the skin to exert the medical effects,and nourish and dredge the meridians.There is no pain if the meridians are smooth flowing,there will be pain if the meridians are blocked,fumigation can be used alone or assisted by other treatment methods to enhance the efficacy.The characteristics of acupuncture are rapid painrelief,economic and convenient,and can quickly relieve pain for patients with low tolerance.

Randomized control study in the influence of different training methods of Tai Chi on Chinese medicine constitution of international students with depression or depression tendency

目的：探讨太极拳不同训练方式对留学生抑郁或抑郁倾向的影响.方法：38名留学生被随机分为太极拳单纯动作练习组（简称单纯动作组）和太极拳动作练习配合呼吸吐纳组（简称呼吸吐纳组）,并比较两组实验前后中医体质的均分变化.结果：与训练前相比,38名留学生中偏颇体质的平均得分明显下降（P〈0.05）.与训练前相比,呼吸吐纳组中气虚型、阳虚型、痰湿型、气滞型的偏颇体质的平均得分显著降低（P〈0.05）.单纯动作组的阳虚型、血瘀型、气滞型的偏颇体质的平均得分也显著下降（P〈0.05）.另外,气虚型、阳虚型、阴虚型、痰湿型、气滞型的偏颇体质的平均得分均显著低于单纯运动组中这些体质的得分,提示太极拳动作练习配合呼吸吐纳的方法优于太极拳单纯动作练习（P〈0.01）.结论：与呼吸吐纳法结合,太极拳动作练习对改善与抑郁或抑郁倾向相关的偏颇体质有更好的效果.

Comparison of intestinal absorption characteristics between rhubarb traditional Chinese medicine preparation and activity ingredients using in situ and in vitro model

Objective: The intestinal absorption characteristics of active ingredients are very important for oral administration of traditional Chinese medicine(TCM) to achieve the desired therapeutic effect.However, a deeper understanding about active ingredients absorption characteristics is still lack. The aim of this study was to investigate the absorption properties and mechanism of rhubarb active ingredients in TCM preparation and pure form.Methods: The intestinal absorption behavior of active ingredients in Shenkang extract(SKE) and rhubarb anthraquinone ingredients(RAI) were investigated by in situ single-pass intestinal perfusion model. And the bidirectional transport characteristics of these active ingredients were assessed by in vitro Caco-2 cell monolayer model.Results: In situ experiment on Sprague-Dawley rats, the effective permeability coefficient values of aloeemodin, emodin and chrysophanol in RAI were higher than those in SKE, and the value of rhein in RAI was lower than that in SKE. But the easily absorbed segments of intestine were consistent for all ingredients,whether in SKE or in RAI. In vitro experiment, the apparent permeability coefficient values of rhein, emodin and chrysophanol in RAI were higher than those in SKE, and this value of aloe-emodin in RAI was lower than that in SKE. But their efflux ratio(ER) values in SKE and RAI were all similar.Conclusion: Four rhubarb anthraquinone ingredients in SKE and RAI have similar absorption mechanism and different absorption behavior, and the microenvironment of the study models influenced their absorption behavior. The results may provide an aid for understanding of the absorption characteristics of the TCM active ingredients in complex environments and the complementarities of different research models.

Multifactor dimensionality reduction analysis of syndrome characteristics of chronic persistent asthma

Objective:To analyze the syndrome characteristics in patients with chronic persistent asthma.Methods:365 patients(121 males,244 females,60.829.1 years old)with chronic persistent asthma were enrolled in this cross-sectional study.The information of syndrome,symptoms,signs,tongue coating and pulse were collected from all patients.The syndrome characteristics of chronic persistent asthma were examined through the multifactor dimensionality reduction(MDR)analysis and the results were verified by the Chi-square test.Results:The results of the MDR analysis and the Chi-square test showed the following positive correlation of the interaction among:the deficiency syndrome of the lung and spleen and deep pulse,disinclination to talk due to lack of qi,fatigue,lassitude and thick tongue coating;the deficiency syndrome of the lung and kidney and dizziness and disinclination to talk due to lack of qi,fatigue,lassitude and pallid complexion;the syndrome of phlegm-heat obstructing the lung and rapid pulse,abdominal distension,disinclination to talk due to lack of qi,frequent urination and lassitude;the syndrome of phlegm-dampness obstructing the lung and disinclination to talk due to lack of qi,greasy coating,fatigue and lassitude.(P<.05 for all).Conclusion:The syndrome of chronic persistent asthma is characterized by fatigue and lassitude due to dysfunction of the lung,spleen and kidney.

八段锦联合放松功对轻中度抑郁的影响研究

【目的】探究中医行为心理疗法八段锦联合放松功干预轻中度抑郁的效果。【方法】将40例轻中度抑郁患者随机分为干预组和对照组,每组各20例。干预组给予八段锦锻炼联合放松功干预治疗,对照组给予西药氢溴酸西酞普兰片治疗,疗程为6周。观察2组患者干预前后汉密尔顿抑郁量表(HAMD)评分、蒙哥马利抑郁量表(MADRS)评分、匹兹堡睡眠质量指数(PSQI)评分以及生活质量综合评定问卷(GQOL-74)评分的变化情况,并评价2组患者的抑郁改善疗效。【结果】(1)抑郁改善疗效方面,治疗6周后,干预组的总有效率为95.0%(19/20),对照组为90.0%(18/20),组间比较(χ2检验),差异无统计学意义(P>0.05)。(2)抑郁程度方面,治疗后,2组患者的HAMD评分和MADRS评分均较治疗前明显下降(P<0.01),但治疗后组间比较,差异均无统计学意义(P>0.05)。(3)生活质量方面,治疗后,2组患者的GQOL-74的躯体功能、心理功能、社会功能、物质生活等各项评分及总分均较治疗前明显改善(P<0.01),但治疗后组间比较,差异均无统计学意义(P>0.05)。(4)睡眠质量方面,治疗后,2组患者的PSQI的睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、催眠药物和日间功能等各项评分及总分均较治疗前明显改善(P<0.01),且干预组对PSQI的睡眠质量、入睡时间评分及总分的改善作用明显优于对照组(P<0.05)。【结论】八段锦锻炼联合放松功干预对轻中度抑郁症状的改善有明确的疗效,可以为轻中度抑郁症患者提供更广泛的选择可能,特别是对西药治疗不耐受的患者更具有一定的优势。

湖湘古代中医药文献的类型与特点述略

湖湘中医药文献既是湖湘先人认识疾病的重要途径,又是湖湘地区中医药知识的重要宝库。从早期的口头传承到简帛、竹木简牍,再到纸质文献,湖湘中医药文献呈现了丰富多样的类型和独特的发展轨迹。周秦两汉时期,湖湘中医药文献开始萌芽,主要以简帛文献为主;魏晋隋唐时期,文献载体逐渐向竹木简牍转变,且养生文献得到发展;宋金元时期,方书集合文献占据主导地位,中医药知识体系更趋完善;明清时期,见证了湖湘中医药文献的鼎盛,特别是处理时疫的文献得到广泛流传。通过厘清湖湘古代中医药文献的类型与特点,展示和挖掘湖湘中医药知识和理论的构建历程,从而促进湖湘中医药及其文献的研究利用。

中医治疗银屑病伴抑郁症的机制研究进展

银屑病是由免疫介导的慢性、炎症性皮肤病,常伴不同程度的心理障碍,其中,银屑病与抑郁症具有显著的关联性,呈现互为因果、互相促进的紧密关系。银屑病伴抑郁症较单纯银屑病危害更大,预后更差,给家庭及社会带来巨大负担,值得临床关注。本文基于银屑病伴抑郁症的西医发病因素及中医病机认识,总结阐述中医治疗银屑病抑郁机制的研究进展,以期为临床诊疗提供新的思路。

中医传统功法在卒中后认知障碍患者中应用效果的Meta分析

目的系统评价中医传统功法对卒中后认知障碍患者的干预效果。方法利用计算机检索The Cochrane Library、PubMed、Embase、Web of Science、中国生物医学文献数据库、中国知网、万方数据知识服务平台、维普中文科技期刊数据库中有关中医传统功法干预卒中后认知障碍患者的随机对照试验,检索时限为建库至2023年12月31日,采用RevMan 5.4软件进行Meta分析。结果共纳入15项随机对照试验研究,包括918例研究对象。Meta分析结果显示,中医传统功法在提高卒中后认知障碍患者的认知功能[SMD=0.86,95%CI(0.68,1.04),P<0.001]、缩短P300检测的潜伏时间[MD=-11.52,95%CI(-16.06,-6.98),P<0.001]、增加P300检测的波幅高度[MD=1.06,95%CI(0.44,1.67),P<0.001]等方面均优于对照组。结论中医传统功法可有效提高卒中后认知障碍患者的认知功能。

造血干细胞移植患者中医序贯式运动方案的构建及应用

目的探讨中医序贯式运动方案对造血干细胞移植患者的康复效果。方法干预小组基于循证方法学,构建造血干细胞移植患者序贯式中医运动方案。选取44例患者作为研究对象,将患者随机分为干预组和对照组各22例。对照组实施常规造血干细胞移植运动康复方案,干预组在此基础上实施序贯式中医运动康复方案。比较两组不同时间简易体能状况、疲劳严重程度、身体质量指数、改良Barthel指数和运动康复过程中不良事件发生率、运动康复依从性。结果移植后14 d、28 d,干预组体能状况、疲劳严重程度、改良Barthel指数和运动康复依从性评分显著优于对照组(均P<0.05),均未发生运动相关不良事件。结论对造血干细胞移植患者实施中医序惯运动方案可行和安全,可提高造血干细胞移植患者运动能力,促进康复。

岭南中医妇科课程标准化教学改革

地域特色课程是中医药院校的新兴课程,是我国发展中医药事业和高等中医药教育教学改革的重要组成部分,课程质量是培育人才的基石。文章基于岭南中医妇科课程标准化建设研究,通过分析目前的中医人才的培育要求及中医院校课程标准化的现状,指出该课程教学改革的必要性,从教材编写、教学设计、教学比例、教师队伍、教学形式、教学方法及考评方式等方面提出思考及实践总结,强调思政立德树人,跟师守正创新。以期为同类课程设置及教学实践提供参考。

中医正骨学古今教学特点刍议

中医正骨学是一门技术性学科,在古今都占有着重要的医疗地位。文章针对中医正骨学的古代和现代教学特点进行讨论,并根据发展的实际情况分析教学模式的变化特点,以便更好地保持我国中医药治疗的特色和优势,使中医正骨学保持学科特色、发挥学科优势,充分利用现代科学技术,走在科技的前线,与现代高新技术相结合,促进其教学发展。

中西医结合康复对不完全性脊髓损伤的影响

目的探讨中西医结合康复对不完全性脊髓损伤(ISCI)患者的影响。方法选择64例不完全性脊髓损伤患者,采用随机数字表简单化分组法(余数法)分为观察组与对照组,各32例,对照组给予常规物理治疗+康复训练,观察组在对照组基础上联合针刺+中医特色功能训练。通过评估美国脊柱损伤学会运动评分(ASIA-MS)、疼痛视觉模拟评分(VAS)、日常生活能力评分(ADL)、10 m最快步行速度测试(10MWT)、6 min步行耐力测试(6MWT)、计时起立-行走测试(TUGT)、Berg平衡量表(BBS)变化情况,分析2组康复效果。结果康复治疗4周时,观察组ASIA-MS、ADL评分高于对照组(P<0.05),VAS评分低于对照组(P<0.05);治疗4周、6周、8周时,观察组10MWT均低于对照组(P<0.05),6MWT均高于对照组(P<0.05);观察组治疗8周时TUGT低于对照组(P<0.05);观察组治疗8周、12周时BBS评分高于对照组(P<0.05)。结论中西医结合康复治疗有利于不完全性脊髓损伤神经再生修复,促进患者步行能力、平衡能力提升。

川派中药炮制技艺的历史源流与特色

川派中药炮制技术作为全国四大炮制流派之一,历来在中药炮制界占据十分重要的地位,是国家级非物质文化遗产。本研究通过对其发展源流进行考证,并总结其发展规律,完善对川派中药炮制的认识与研究,找出川派中药炮制的独到之处,推动川派中药炮制的保护传承与创新发展。

浅谈中药特色技术传承人才培训项目学习心得

中药特色技术的传承是继承和发展中医药事业的重要环节。通过参加中药特色技术传承人才培训项目的学习,回顾各基地游学经历,结合实际工作情况,从丰富理论知识、提升专业能力,学以致用、加强中医药服务能力,以及弘扬中医药文化、提升教学水平等几个方面总结学习心得。目的是为中医药从业者提供可借鉴的学习经验,也为中药特色技术传承人才培训项目更好地进行人才培训提供参考意见,从而促进中医药事业的继承和发展。

基于固本培元理论探究中医药治疗虚性功能性便秘的临床特色

虚性功能性便秘为内科常见疾病,中医在该病诊疗方面有一定的特色与优势。文章基于固本培元理论,从脾肾功能角度探究虚性功能性便秘的病机。在固本培元理论的指导下,古今医家重视调补气血,补益中焦脾胃并兼顾下焦肾元。治疗上多用方药,寓通于补;辅以针刺,相得益彰;借助艾灸,痼疾得消。通过梳理古代医家临床经验结合现代临床验案,系统整理中医药治疗该病的临床特色,为临床提供诊疗思路。

手指操联合中医情志护理对恢复期脑卒中患者康复效果评价

目的探讨手指操联合中医情志护理对恢复期脑卒中患者的康复效果,为临床护理实践提供理论指导。方法选取宁晋县中西医结合医院2022年2月—2023年2月90例恢复期脑卒中患者为研究对象,按照组间基线资料均衡可比的原则将其分为对照组和观察组,各45例。对照组患者均给予常规基础护理、康复治疗与锻炼、预防并发症护理等,观察组在对照组基础上给予手指操训练联合中医情志护理。分别于干预前及干预后2周、4周、8周,采用改良Barthel指数量表、汉密尔顿焦虑量表(Hamilton Anxiety Scale,HAMA)、汉密尔顿抑郁量表(Hamilton Depression Scale,HAMD)与Fugl-Meyer运动功能评价量表评价两组患者日常生活活动能力、焦虑评分、抑郁评分及上下肢运动功能评分。采用满意度量表评价两组患者的护理满意程度。结果干预后观察组患者焦虑、抑郁评分低于对照组,上、下肢运动功能评分及Barthel指数评分均高于对照组,两组患者HAMA评分、HAMD评分、Fugl-Meyer评分及Barthel指数比较,组间、不同时间点、组间与不同时间点交互作用差异均有统计学意义(P<0.05)。观察组患者护理满意程度高于对照组,差异具有统计学意义(P<0.05)。结论手指操联合中医情志护理可以有效改善脑卒中患者的焦虑、抑郁状态,提高其日常生活自理能力,促进患者上下肢功能恢复,有利于患者早日康复,从而提高患者的满意度。

“互联网+医疗”背景下2020—2022年儿科中医门诊线上与线下就诊人群特征比较研究

目的 为比较儿科中医门诊线上线下就诊模式的人群特征,以提高医疗服务质量和医院管理效率。方法 收集2020年1月至2022年12月,首都医科大学附属北京儿童医院中医科门诊院内信息系统的全数据就诊记录,设置人口学、时间、地区等观察指标。结果 线上诊疗组与线下诊疗组的人口学特征(性别、年龄、民族、就诊时的主要诊断)、时间特征(时间序列分析、就诊日期、就诊班次)、地区特征(人类发展指数分区、地理分区)比较,差异有统计学意义(P<0.01)。少数民族患儿(7.29%vs. 4.04%)、血液及造血器官疾病(48.55%vs. 10.90%)、肌肉和骨骼系统的结缔组织病(1.84%vs. 0.84%)、工作日就诊(96.95%vs. 79.29%)、上午就诊(86.41%vs. 54.80%)、极低人类发展指数地区(0.57%vs. 0.24%)的线上患儿比例更高(P<0.01)。结论“互联网+”医疗模式在儿科中医门诊具备推广意义;线上诊疗方式有效提高医疗服务公平性,有效促进优质医疗资源的下沉;同时两种诊疗方式存在就医倾向性、响应度、诊断内容的差异,医疗机构应因势利导,发挥两种模式的优势,不断完善新时代中医药的发展与转型。