We read with great interest the recent article by Erenson(2023)entitled“Dispersion characteristics of clayey soils containing waste rubber particles”.The author has studied the dispersion characteristics of clayey s...We read with great interest the recent article by Erenson(2023)entitled“Dispersion characteristics of clayey soils containing waste rubber particles”.The author has studied the dispersion characteristics of clayey soils containing different percentages of waste rubber particles(WRPs)by performing several tests(viz.consistency limit,linear shrinkage limit,double hydrometer,crumb test and pinhole test)and scanning electron microscopy(SEM)analysis on five clayey(viz.Na-activated bentonite,refined ball clay,Ukrainian kaolin,Avanos kaolin and Afyon clay)samples containing 0%,5%,10%and 15%WRPs.It should be noted that Erenson(2023)has presented some interesting observations,but there are some serious issues that we want to share through this discussion and request the author of the original paper to address them to avoid their persistence in the scientific literature.展开更多
AIM: To understand the distinct, clinical features of myotonia congenita in China. METHODS: Case reports of myotonia congenita were retrieved from the Chinese Journal Full-text database, dating between 1980 and 2007...AIM: To understand the distinct, clinical features of myotonia congenita in China. METHODS: Case reports of myotonia congenita were retrieved from the Chinese Journal Full-text database, dating between 1980 and 2007, and analyzed for clinical characteristics of myotonia congenita. RESULTS: There were 35 published reports and 258 cases about myotonia congenita. Six reports (62 cases) were excluded due to lack of clinical data, imprecise diagnosis, or duplication. Finally, 29 published reports and 196 cases (140 males and 56 females) were included in this analysis. About 78.6% of patients were diagnosed with myotonia congenita before the age of 20, and among these, 86.1% were classified as dominant inheritance. Lower and upper extremities were frequently affected with severe symptoms. Eyelids, mouth and lingual muscles, and trunk muscles and cervical muscles were less frequently involved. However, muscles for swallowing, sphincter muscles, and smooth muscles were not involved. There were no reports of cataracts, cardiac conduction block, or dyscrinism. myotonia congenita symptoms were induced or aggravated by cold temperatures in 71.9% of the patients and warming-up effect occurred in 95.6% of the patients. Muscle hypertrophy was observed in 69.6% and percussion of muscles in 76.5% of the patients. Myotonia potential or myotonia-like potential was detected in all patients using electromyography. Muscle fiber swelling or hypertrophy was frequently detected through muscular biopsy. CONCLUSION: Myotonia congenita frequently occurs in males before the age of 20, in particular as the autosomal dominant form of myotonia congenita. Skeletal muscles throughout the body, especially the lower and upper extremities, are involved. However, muscles for swallowing, sphincter muscles, and smooth muscles are not involved. Warming-up effect is the main characteristic of myotonia congenita.展开更多
As an important branch of literature, children's literature is exerting a pivotal role in social education. From the perspec-tive of reception aesthetics, English version of Cao Wenxuan's work Bronze and Sunfl...As an important branch of literature, children's literature is exerting a pivotal role in social education. From the perspec-tive of reception aesthetics, English version of Cao Wenxuan's work Bronze and Sunflower is studied from four aspects:horizon of expectation, indeterminacy, aesthetic distance and fusion of horizons. In reception aesthetics, target readers-children are the center of the reading. So translation methods are to satisfy children's demand. It has also been found out that there are some features for children's literature translation include using colloquial words, concise sentence structure and the combination of domestication and foreignization.展开更多
It is analyzed from the time and society development background that the social nature was subject to concrete changes in the early Qing Dynasty,middle and latter periods of Qing Dynasty and the late Qing Dynasty due ...It is analyzed from the time and society development background that the social nature was subject to concrete changes in the early Qing Dynasty,middle and latter periods of Qing Dynasty and the late Qing Dynasty due to different China's social development backgrounds,but the establishing target of the national thought subject in the literature development characteristics is not transferred. The revitalization of national development is considered as the fundamental to establish positive national spirit and directly safeguard and defend the national dignity,so that the literature in the Qing Dynasty becomes the cultural thought action force to promote developing and growing Chinese nation.展开更多
In recent years,China’s public diplomacy has flourished,with literary exchanges and external communication undoubtedly becoming an essential part.Particularly with the progress of Chinese technology,science fiction l...In recent years,China’s public diplomacy has flourished,with literary exchanges and external communication undoubtedly becoming an essential part.Particularly with the progress of Chinese technology,science fiction literature has become a focal point both domestically and internationally.This paper investigates the background of the Chinese science fiction literature’s national characteristics,the manifestation of these characteristics in works,and the advantages of communication from three aspects.It also explores new ideas for the external communication of Chinese science fiction literature from the perspective of public diplomacy,inspiring new pathways for the integration of Chinese culture with the world,and telling Chinese stories to the world.展开更多
Alice's Adventures in Wonderland literature development has been blocked by the monotonous theme orientation and plots off the real life. In this paper, Alice has served as an illustrative case study to present so...Alice's Adventures in Wonderland literature development has been blocked by the monotonous theme orientation and plots off the real life. In this paper, Alice has served as an illustrative case study to present some enlightenment to show creation should base on child-orientation and give detail opinions to help Chinese children's literary writers rethink the children's literature before and during the creation.展开更多
With the development of global economic integration in recent years, Chinese culture is influenced by the penetration of Western culture, and there are many excellent English literature works. This paper focuses on ho...With the development of global economic integration in recent years, Chinese culture is influenced by the penetration of Western culture, and there are many excellent English literature works. This paper focuses on how to translate excellent English literature into appropriate Chinese. It shows the key meaning of English literary translation which embodies artistic characteristics and aesthetic value. Then it analyzes how to reflect aesthetic value and artistic characteristics in English literary translation.展开更多
Reading is a fundmental activity for children,while to some degree british children can not gain emotional experienceand aesthetic experience in contemporary children's literature.Education system、modern technolo...Reading is a fundmental activity for children,while to some degree british children can not gain emotional experienceand aesthetic experience in contemporary children's literature.Education system、modern technology as well as patents should be responsible for the dilemma of emotional deficiency。展开更多
Purpose The paper shows the interpretive impact of different constructions of the point of view available to the reader/viewer in book and animated movie versions of a children's picture book,a novel for pre-adole...Purpose The paper shows the interpretive impact of different constructions of the point of view available to the reader/viewer in book and animated movie versions of a children's picture book,a novel for pre-adolescents/early teenagers,and a graphic novel for adolescents and adults.Design/Approach/Methods Excerpts from book and animated movie versions of the same story are compared using multimodal analysis of interpersonal meaning to show how the reader/viewer is positioned in relation to the characters in each version,complemented by analyses of ideational meaning to show the effect of point of view on interpretive possibilities.Findings Focusing mainly on multimodal construction of point of view,the analyses show how interpretive possibilities of ostensibly the same story are significantly reconfigured in animated adaptations compared with book versions even when the verbal narrative remains substantially unchanged.Originality/Value The study shows that it is crucial to students’critical appreciation of,and their creative contribution to,their evolving digital literary culture that in this new era of educational technology,attention in literacy and literary education focuses on developing understandings of digital multimodal narrative art,and that animated movie adaptations are not presented pedagogically as isomorphic with,or simply adjunct to,corresponding book versions.展开更多
When translating children's literature, the characteristics of the target readers can not be neglected. However, in thetranslation of literary works in China, translation of children's literature in China has ...When translating children's literature, the characteristics of the target readers can not be neglected. However, in thetranslation of literary works in China, translation of children's literature in China has always been ignored. E-C translation practicein children's literature and the theoretical study are of imbalance. When it comes to the theoretical study of E-C translation of chil-dren's literature, it is far backward. Skopostheorie holds that the purpose of translation is the primary rule to be followed, and pro-vides children's literature translation with theory evidence. The Borrowers was introduced into China in 1990, highly appreciatedby readers. However, the related research in the translation of this book is poor. This paper takes Skopostheorie as the theoreticalframework and combines the characteristics of children's literature, discussing the different Chinese translation versions of the Brit-ish children's literature The Borrowers. This paper makes a comparative analysis on the advantages and disadvantages of differentChinese versions, and summarizes the methods of translating children's literature.展开更多
OBJECTIVE: To thoroughly explore the clinical characteristics of Huntington disease in China. METHODS: A computer-based online search of China National Knowledge Infrastructure was performed to review case reports c...OBJECTIVE: To thoroughly explore the clinical characteristics of Huntington disease in China. METHODS: A computer-based online search of China National Knowledge Infrastructure was performed to review case reports concerning Huntington disease published between 1980 and 2008; the clinical characteristics were analyzed. RESULTS: A total of 80 studies involving 243 patients (142 males and 101 females) were collected, 82.0% of which were from provinces of North China. In addition, 97.1% of the cases had a family history of Huntington disease, and paternal inheritance (64.6%) was greater than maternal inheritance (35.4%). Moreover, onset age was significantly less than from maternal inheritance. The mean onset age of Huntington disease was (35.2 ± 11.5) years, mean age of death was (45.6 ± 13.5) years, and the mean course of disease from onset to death was (11.6 ± 5.6) years. Onset characterized by involuntary movement accounted for 47.7%, including 66.4% in the entire body, 16.4% in the upper limbs, and 14.7% in the head and face. Psychiatric symptoms accounted for 18.1%, and disturbed intelligence accounted for 2.1%. With disease progression, 99.5% of patients exhibited involuntary movement, 69.8% displayed cognitive impairment, and 39.2% suffered from psychiatric symptoms. In addition, 38.7% of patients were complicated by dysarthria, dysphagia, and cough after drinking. A total of 70.8% of patients exhibited an abnormal electroencephalogram, 18.8% had mild abnormalities in the cerebrospinal fluid, and 70.1% displayed brain atrophy and lateral ventriculomegaly on CT or MRI. A total of 88.9% of patients scored ≤ 23 in the Mini-Mental State Examination (MMSE). Of the reported patients, only 22 underwent/T15 gene testing with positive results. CONCLUSION: Huntington disease is more frequently detected in males than females, and the majority has a family history. The disease has high incidence in Northern China, in particular with paternal inheritance. In addition, the disease often struck middle-aged people, and the time of onset in paternal inheritance was earlier than maternal inheritance. There were no significant differences in age of onset between males and females, and the course of disease was not related to paternal or maternal inheritance. The symptoms of onset included involuntary movement, complicated by psychiatric symptoms, and rarely cognitive impairment. In addition, involuntary movement of the pharynx was commonly observed in patients. Genetic detection has been the gold standard for clinical diagnosis of Huntington disease, and more attention should be paid to this detection method.展开更多
OBJECTIVE: To thoroughly investigate clinical characteristics of progressive supranuclear palsy (PSP) in a Chinese population. METHODS: Computer-based online searches through China National Knowledge Infrastructur...OBJECTIVE: To thoroughly investigate clinical characteristics of progressive supranuclear palsy (PSP) in a Chinese population. METHODS: Computer-based online searches through China National Knowledge Infrastructure and Weipu Periodical Database were performed to collect case reports of PSP published between 1980 and 2009. Clinical characteristics were analyzed. RESULTS: A total of 58 studies comprising 105 patients (76 males and 29 females) were included. All cases were sporadic and free of family history. The mean age at onset was 60.6 _+ 9.1 years, and the mean course from onset of symptoms to diagnosis was 3.4 + 2.4 years. The male-to-female ratio was approximately 3: 1. Onset was characterized by akinetic-dgid features and accounted for 34.3% of all cases, followed by early postural instability (25.5%), pseudobulbar palsy (9.8%), cognitive impairment (9.8%), and vertical supranuclear ophthalmoplegia (7.8%). With disease progression, vertical supranuclear ophthalmoplegia was reported in 95.1% of cases, followed by akinetic-rigid features (83.3%), pseudobulbar palsy (82.4%), axial dystonia (75.5%), cognitive impairment (72.5%), and early postural instability (69.6%). A total of 70.5% of patients exhibited abnormal electroencephalograms, and 21.4% exhibited mild abnormalities in cerebrospinal fluid. Brain CT scanning results of 37 patients showed 37.8% with midbrain and concurrent cerebral hemisphere atrophy, and 5.4% and 24.3% with midbrain and cerebral hemisphere atrophy, respectively. Brain MRI scanning results of 55 patients revealed a total of 16.4% patients with midbrain atrophy, 23.6% with midbrain and concurrent cerebral hemisphere atrophy, 32.7% with cerebral hemisphere atrophy, and 11% with brainstem atrophy. The percentage of midbrain atrophy revealed by MRI was greater than by CT. All 11 patients subjected to Mini-Mental State Examination scored 〈 23. A total of 10 patients underwent brain electrophysiological examination, and 80% presented with abnormalities of cerebral-evoked potential. A total of 33.3% patients presented with neurogenic damage of anal sphincter electromyography. Nine cases were neuropathologically diagnosed, and all displayed tau-positive argyrophilic globous neurofibrillary tangles, tuft-shaped astrocytes, and coiled bodies. Gene diagnosis was not performed. A total of 40 patients were misdiagnosed, including 23 (58%) as Parkinson's disease and seven (18%) as Parkinsonism; 44 patients were treated by madopar, artane, or amantadine, and only seven (16%) improved in movement. No patients exhibited improved eye movement. Of 4 patients treated with madopar and dopa agonists, 2 improved in movement. In addition, movement improved in 3 patients treated with madopar and monoamine oxidase B. CONCLUSION: PSP is a sporadic disease that often strikes middle or elderly individuals. There are no significant differences in age of onset between male and female patients, although disease progression is more rapid in female patients, likely because the time from symptom onset to disease diagnosis in females is less than in male. Akinetic-rigid features and early postural instability are the most common symptoms of onset. With disease progression, the incidence of vertical supranuclear ophthalmoplegia and akinetic-rigid features increases. MRI is a common, sensitive, and noninvasive supplemental test. However, PSP is frequently misdiagnosed as Parkinson's disease or Parkinsonism during the early stage, and anti-Parkinson treatments remain ineffective.展开更多
Singapore's Chinese literature education has continuously evolved and advanced over the years, forming a unique style in global Chinese education, which can be described as: "Singapore pie". Through its bilingual ...Singapore's Chinese literature education has continuously evolved and advanced over the years, forming a unique style in global Chinese education, which can be described as: "Singapore pie". Through its bilingual policy, the Singapore government has been committed to creating a pool of bicultural talents, by supplementing the teaching of Chinese language with classes on Chinese literature and culture. This thesis seeks to understand the pros and cons of Chinese literature education in Singapore by analysing its development over the years. The teaching of Chinese literature began with the first wave of Chinese migration to Nanyang in the 19th century, and from there, it went through three phases of development: relocation, adjustment, and burgeoning.展开更多
British and American literary classics are very rich,and they are the bright pearls in the treasure house of world literature.British and American literary creations are produced under unique regional cultures.Differe...British and American literary classics are very rich,and they are the bright pearls in the treasure house of world literature.British and American literary creations are produced under unique regional cultures.Different regional cultures have their own language characteristics and connotations.To understand the work deeply,they must have a deep understanding and understanding of their background culture.British and American literature is an important reflection of British and American culture.By analyzing the language characteristics of British and American literature,we can better understand the development characteristics of British and American culture and strengthen our understanding of the background and connotation of British and American culture.Next,this paper will analyze the linguistic characteristics of British and American literary works from a cross-cultural perspective to strengthen the understanding and cognition of British and American culture.展开更多
This study explores the realization of functional equivalence through a comparative analysis of Ba Jin's and Lin Huiyin's Chinese versions of The Nightingale and the Rose at the levels of meaning,style and cul...This study explores the realization of functional equivalence through a comparative analysis of Ba Jin's and Lin Huiyin's Chinese versions of The Nightingale and the Rose at the levels of meaning,style and culture.Ba's version achieves the highest functional equivalence,especially at the level of style.By contrast,with strong personal style and characteristics of the Republicanperiod,Lin's version is difficult for the children to read and comprehend.Besides,for both translators fail to understand the original texts completely,their versions mislead the readers as to meanings and cultural interpretations.展开更多
基于Web of Science数据库1900—2020年资源配置扭曲相关文献,采用文献计量法和内容分析法,探讨资源配置扭曲领域的文献外部特征和学科知识结构。结果表明:第一,资源配置扭曲领域发文量呈上升趋势,且研究多涉及经济学和商学领域;第二,...基于Web of Science数据库1900—2020年资源配置扭曲相关文献,采用文献计量法和内容分析法,探讨资源配置扭曲领域的文献外部特征和学科知识结构。结果表明:第一,资源配置扭曲领域发文量呈上升趋势,且研究多涉及经济学和商学领域;第二,来自欧美国家的学者、期刊和科研机构在资源配置扭曲领域处于领先地位,国内学者、期刊和科研机构尚未形成稳定的影响力;第三,资源配置扭曲领域的学科知识结构包括四部分:扭曲成因研究、扭曲测度研究、扭曲效应研究和扭曲治理研究。最后,从研究范围、研究方法、形成机理和治理框架四个方面对资源配置扭曲领域未来研究方向提出建议。展开更多
文摘We read with great interest the recent article by Erenson(2023)entitled“Dispersion characteristics of clayey soils containing waste rubber particles”.The author has studied the dispersion characteristics of clayey soils containing different percentages of waste rubber particles(WRPs)by performing several tests(viz.consistency limit,linear shrinkage limit,double hydrometer,crumb test and pinhole test)and scanning electron microscopy(SEM)analysis on five clayey(viz.Na-activated bentonite,refined ball clay,Ukrainian kaolin,Avanos kaolin and Afyon clay)samples containing 0%,5%,10%and 15%WRPs.It should be noted that Erenson(2023)has presented some interesting observations,but there are some serious issues that we want to share through this discussion and request the author of the original paper to address them to avoid their persistence in the scientific literature.
文摘AIM: To understand the distinct, clinical features of myotonia congenita in China. METHODS: Case reports of myotonia congenita were retrieved from the Chinese Journal Full-text database, dating between 1980 and 2007, and analyzed for clinical characteristics of myotonia congenita. RESULTS: There were 35 published reports and 258 cases about myotonia congenita. Six reports (62 cases) were excluded due to lack of clinical data, imprecise diagnosis, or duplication. Finally, 29 published reports and 196 cases (140 males and 56 females) were included in this analysis. About 78.6% of patients were diagnosed with myotonia congenita before the age of 20, and among these, 86.1% were classified as dominant inheritance. Lower and upper extremities were frequently affected with severe symptoms. Eyelids, mouth and lingual muscles, and trunk muscles and cervical muscles were less frequently involved. However, muscles for swallowing, sphincter muscles, and smooth muscles were not involved. There were no reports of cataracts, cardiac conduction block, or dyscrinism. myotonia congenita symptoms were induced or aggravated by cold temperatures in 71.9% of the patients and warming-up effect occurred in 95.6% of the patients. Muscle hypertrophy was observed in 69.6% and percussion of muscles in 76.5% of the patients. Myotonia potential or myotonia-like potential was detected in all patients using electromyography. Muscle fiber swelling or hypertrophy was frequently detected through muscular biopsy. CONCLUSION: Myotonia congenita frequently occurs in males before the age of 20, in particular as the autosomal dominant form of myotonia congenita. Skeletal muscles throughout the body, especially the lower and upper extremities, are involved. However, muscles for swallowing, sphincter muscles, and smooth muscles are not involved. Warming-up effect is the main characteristic of myotonia congenita.
文摘As an important branch of literature, children's literature is exerting a pivotal role in social education. From the perspec-tive of reception aesthetics, English version of Cao Wenxuan's work Bronze and Sunflower is studied from four aspects:horizon of expectation, indeterminacy, aesthetic distance and fusion of horizons. In reception aesthetics, target readers-children are the center of the reading. So translation methods are to satisfy children's demand. It has also been found out that there are some features for children's literature translation include using colloquial words, concise sentence structure and the combination of domestication and foreignization.
基金Phased objectives of financing scheme"research on Yan-Li School--with the center of Li Gong"for young core teachers in Henan institutions of higher education in 2012,project No.:2012 GGJS-155.
文摘It is analyzed from the time and society development background that the social nature was subject to concrete changes in the early Qing Dynasty,middle and latter periods of Qing Dynasty and the late Qing Dynasty due to different China's social development backgrounds,but the establishing target of the national thought subject in the literature development characteristics is not transferred. The revitalization of national development is considered as the fundamental to establish positive national spirit and directly safeguard and defend the national dignity,so that the literature in the Qing Dynasty becomes the cultural thought action force to promote developing and growing Chinese nation.
基金supported by the foundation of SFLEP National University Foreign Language Teaching Research Project(No.2019SH0039B)and Hebei Provincial Social Science Foundation(No.HB19WW007).
文摘In recent years,China’s public diplomacy has flourished,with literary exchanges and external communication undoubtedly becoming an essential part.Particularly with the progress of Chinese technology,science fiction literature has become a focal point both domestically and internationally.This paper investigates the background of the Chinese science fiction literature’s national characteristics,the manifestation of these characteristics in works,and the advantages of communication from three aspects.It also explores new ideas for the external communication of Chinese science fiction literature from the perspective of public diplomacy,inspiring new pathways for the integration of Chinese culture with the world,and telling Chinese stories to the world.
文摘Alice's Adventures in Wonderland literature development has been blocked by the monotonous theme orientation and plots off the real life. In this paper, Alice has served as an illustrative case study to present some enlightenment to show creation should base on child-orientation and give detail opinions to help Chinese children's literary writers rethink the children's literature before and during the creation.
文摘With the development of global economic integration in recent years, Chinese culture is influenced by the penetration of Western culture, and there are many excellent English literature works. This paper focuses on how to translate excellent English literature into appropriate Chinese. It shows the key meaning of English literary translation which embodies artistic characteristics and aesthetic value. Then it analyzes how to reflect aesthetic value and artistic characteristics in English literary translation.
文摘Reading is a fundmental activity for children,while to some degree british children can not gain emotional experienceand aesthetic experience in contemporary children's literature.Education system、modern technology as well as patents should be responsible for the dilemma of emotional deficiency。
文摘Purpose The paper shows the interpretive impact of different constructions of the point of view available to the reader/viewer in book and animated movie versions of a children's picture book,a novel for pre-adolescents/early teenagers,and a graphic novel for adolescents and adults.Design/Approach/Methods Excerpts from book and animated movie versions of the same story are compared using multimodal analysis of interpersonal meaning to show how the reader/viewer is positioned in relation to the characters in each version,complemented by analyses of ideational meaning to show the effect of point of view on interpretive possibilities.Findings Focusing mainly on multimodal construction of point of view,the analyses show how interpretive possibilities of ostensibly the same story are significantly reconfigured in animated adaptations compared with book versions even when the verbal narrative remains substantially unchanged.Originality/Value The study shows that it is crucial to students’critical appreciation of,and their creative contribution to,their evolving digital literary culture that in this new era of educational technology,attention in literacy and literary education focuses on developing understandings of digital multimodal narrative art,and that animated movie adaptations are not presented pedagogically as isomorphic with,or simply adjunct to,corresponding book versions.
文摘When translating children's literature, the characteristics of the target readers can not be neglected. However, in thetranslation of literary works in China, translation of children's literature in China has always been ignored. E-C translation practicein children's literature and the theoretical study are of imbalance. When it comes to the theoretical study of E-C translation of chil-dren's literature, it is far backward. Skopostheorie holds that the purpose of translation is the primary rule to be followed, and pro-vides children's literature translation with theory evidence. The Borrowers was introduced into China in 1990, highly appreciatedby readers. However, the related research in the translation of this book is poor. This paper takes Skopostheorie as the theoreticalframework and combines the characteristics of children's literature, discussing the different Chinese translation versions of the Brit-ish children's literature The Borrowers. This paper makes a comparative analysis on the advantages and disadvantages of differentChinese versions, and summarizes the methods of translating children's literature.
文摘OBJECTIVE: To thoroughly explore the clinical characteristics of Huntington disease in China. METHODS: A computer-based online search of China National Knowledge Infrastructure was performed to review case reports concerning Huntington disease published between 1980 and 2008; the clinical characteristics were analyzed. RESULTS: A total of 80 studies involving 243 patients (142 males and 101 females) were collected, 82.0% of which were from provinces of North China. In addition, 97.1% of the cases had a family history of Huntington disease, and paternal inheritance (64.6%) was greater than maternal inheritance (35.4%). Moreover, onset age was significantly less than from maternal inheritance. The mean onset age of Huntington disease was (35.2 ± 11.5) years, mean age of death was (45.6 ± 13.5) years, and the mean course of disease from onset to death was (11.6 ± 5.6) years. Onset characterized by involuntary movement accounted for 47.7%, including 66.4% in the entire body, 16.4% in the upper limbs, and 14.7% in the head and face. Psychiatric symptoms accounted for 18.1%, and disturbed intelligence accounted for 2.1%. With disease progression, 99.5% of patients exhibited involuntary movement, 69.8% displayed cognitive impairment, and 39.2% suffered from psychiatric symptoms. In addition, 38.7% of patients were complicated by dysarthria, dysphagia, and cough after drinking. A total of 70.8% of patients exhibited an abnormal electroencephalogram, 18.8% had mild abnormalities in the cerebrospinal fluid, and 70.1% displayed brain atrophy and lateral ventriculomegaly on CT or MRI. A total of 88.9% of patients scored ≤ 23 in the Mini-Mental State Examination (MMSE). Of the reported patients, only 22 underwent/T15 gene testing with positive results. CONCLUSION: Huntington disease is more frequently detected in males than females, and the majority has a family history. The disease has high incidence in Northern China, in particular with paternal inheritance. In addition, the disease often struck middle-aged people, and the time of onset in paternal inheritance was earlier than maternal inheritance. There were no significant differences in age of onset between males and females, and the course of disease was not related to paternal or maternal inheritance. The symptoms of onset included involuntary movement, complicated by psychiatric symptoms, and rarely cognitive impairment. In addition, involuntary movement of the pharynx was commonly observed in patients. Genetic detection has been the gold standard for clinical diagnosis of Huntington disease, and more attention should be paid to this detection method.
文摘OBJECTIVE: To thoroughly investigate clinical characteristics of progressive supranuclear palsy (PSP) in a Chinese population. METHODS: Computer-based online searches through China National Knowledge Infrastructure and Weipu Periodical Database were performed to collect case reports of PSP published between 1980 and 2009. Clinical characteristics were analyzed. RESULTS: A total of 58 studies comprising 105 patients (76 males and 29 females) were included. All cases were sporadic and free of family history. The mean age at onset was 60.6 _+ 9.1 years, and the mean course from onset of symptoms to diagnosis was 3.4 + 2.4 years. The male-to-female ratio was approximately 3: 1. Onset was characterized by akinetic-dgid features and accounted for 34.3% of all cases, followed by early postural instability (25.5%), pseudobulbar palsy (9.8%), cognitive impairment (9.8%), and vertical supranuclear ophthalmoplegia (7.8%). With disease progression, vertical supranuclear ophthalmoplegia was reported in 95.1% of cases, followed by akinetic-rigid features (83.3%), pseudobulbar palsy (82.4%), axial dystonia (75.5%), cognitive impairment (72.5%), and early postural instability (69.6%). A total of 70.5% of patients exhibited abnormal electroencephalograms, and 21.4% exhibited mild abnormalities in cerebrospinal fluid. Brain CT scanning results of 37 patients showed 37.8% with midbrain and concurrent cerebral hemisphere atrophy, and 5.4% and 24.3% with midbrain and cerebral hemisphere atrophy, respectively. Brain MRI scanning results of 55 patients revealed a total of 16.4% patients with midbrain atrophy, 23.6% with midbrain and concurrent cerebral hemisphere atrophy, 32.7% with cerebral hemisphere atrophy, and 11% with brainstem atrophy. The percentage of midbrain atrophy revealed by MRI was greater than by CT. All 11 patients subjected to Mini-Mental State Examination scored 〈 23. A total of 10 patients underwent brain electrophysiological examination, and 80% presented with abnormalities of cerebral-evoked potential. A total of 33.3% patients presented with neurogenic damage of anal sphincter electromyography. Nine cases were neuropathologically diagnosed, and all displayed tau-positive argyrophilic globous neurofibrillary tangles, tuft-shaped astrocytes, and coiled bodies. Gene diagnosis was not performed. A total of 40 patients were misdiagnosed, including 23 (58%) as Parkinson's disease and seven (18%) as Parkinsonism; 44 patients were treated by madopar, artane, or amantadine, and only seven (16%) improved in movement. No patients exhibited improved eye movement. Of 4 patients treated with madopar and dopa agonists, 2 improved in movement. In addition, movement improved in 3 patients treated with madopar and monoamine oxidase B. CONCLUSION: PSP is a sporadic disease that often strikes middle or elderly individuals. There are no significant differences in age of onset between male and female patients, although disease progression is more rapid in female patients, likely because the time from symptom onset to disease diagnosis in females is less than in male. Akinetic-rigid features and early postural instability are the most common symptoms of onset. With disease progression, the incidence of vertical supranuclear ophthalmoplegia and akinetic-rigid features increases. MRI is a common, sensitive, and noninvasive supplemental test. However, PSP is frequently misdiagnosed as Parkinson's disease or Parkinsonism during the early stage, and anti-Parkinson treatments remain ineffective.
文摘Singapore's Chinese literature education has continuously evolved and advanced over the years, forming a unique style in global Chinese education, which can be described as: "Singapore pie". Through its bilingual policy, the Singapore government has been committed to creating a pool of bicultural talents, by supplementing the teaching of Chinese language with classes on Chinese literature and culture. This thesis seeks to understand the pros and cons of Chinese literature education in Singapore by analysing its development over the years. The teaching of Chinese literature began with the first wave of Chinese migration to Nanyang in the 19th century, and from there, it went through three phases of development: relocation, adjustment, and burgeoning.
文摘British and American literary classics are very rich,and they are the bright pearls in the treasure house of world literature.British and American literary creations are produced under unique regional cultures.Different regional cultures have their own language characteristics and connotations.To understand the work deeply,they must have a deep understanding and understanding of their background culture.British and American literature is an important reflection of British and American culture.By analyzing the language characteristics of British and American literature,we can better understand the development characteristics of British and American culture and strengthen our understanding of the background and connotation of British and American culture.Next,this paper will analyze the linguistic characteristics of British and American literary works from a cross-cultural perspective to strengthen the understanding and cognition of British and American culture.
文摘This study explores the realization of functional equivalence through a comparative analysis of Ba Jin's and Lin Huiyin's Chinese versions of The Nightingale and the Rose at the levels of meaning,style and culture.Ba's version achieves the highest functional equivalence,especially at the level of style.By contrast,with strong personal style and characteristics of the Republicanperiod,Lin's version is difficult for the children to read and comprehend.Besides,for both translators fail to understand the original texts completely,their versions mislead the readers as to meanings and cultural interpretations.
文摘基于Web of Science数据库1900—2020年资源配置扭曲相关文献,采用文献计量法和内容分析法,探讨资源配置扭曲领域的文献外部特征和学科知识结构。结果表明:第一,资源配置扭曲领域发文量呈上升趋势,且研究多涉及经济学和商学领域;第二,来自欧美国家的学者、期刊和科研机构在资源配置扭曲领域处于领先地位,国内学者、期刊和科研机构尚未形成稳定的影响力;第三,资源配置扭曲领域的学科知识结构包括四部分:扭曲成因研究、扭曲测度研究、扭曲效应研究和扭曲治理研究。最后,从研究范围、研究方法、形成机理和治理框架四个方面对资源配置扭曲领域未来研究方向提出建议。