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冠心病患者血清lncRNA H19、CHAST的表达水平及临床意义
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作者 李鹏 王勋 +3 位作者 韩翠敏 汪明琅 王怡练 孙黎明 《医学研究杂志》 2024年第1期121-125,共5页
目的探讨冠心病(coronary heart disease,CHD)患者血清长链非编码RNA(lncRNA)H19、CHAST的表达水平及临床意义。方法选取2021年6月~2022年5月在笔者科室住院的冠心病患者135例,其中急性冠状动脉综合征76例,慢性冠状动脉综合征59例,选取... 目的探讨冠心病(coronary heart disease,CHD)患者血清长链非编码RNA(lncRNA)H19、CHAST的表达水平及临床意义。方法选取2021年6月~2022年5月在笔者科室住院的冠心病患者135例,其中急性冠状动脉综合征76例,慢性冠状动脉综合征59例,选取同期住院且经冠状动脉造影排除CHD的对照组62例。采用实时荧光定量PCR(RT-PCR)法测量各组血清lncRNA H19、lncRNA CHAST的表达水平,同时检测各组血清超敏C反应蛋白(high sensitivity C-reactive protein,hs-CRP)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、白细胞介素(interleukin,IL)-6、低密度脂蛋白(low density lipoprotein,LDL)、高密度脂蛋白(high density lipoprotein,HDL)等指标。采用ROC曲线分析血清lncRNA H19、lncRNA CHAST表达水平对CHD的诊断价值;Pearson相关性分析评估lncRNA H19、lncRNA CHAST表达水平与hs-CRP、TNF-α、IL-6、LDL、HDL等因素的相关性;Logistics回归分析CHD的危险因素。结果CHD组血清lncRNA H19、lncRNA CHAST表达水平较对照组升高(P<0.05)。CHD组hs-CRP、IL-6、TNF-α、LDL水平高于对照组(P<0.05),HDL水平低于对照组(P<0.05),lncRNA H19、lncRNA CHAST表达水平与hs-CRP、IL-6、TNF-α、LDL等指标呈正相关(P<0.05),与HDL呈负相关(P<0.05)。lncRNA H19、lncRNA CHAST为CHD的危险因素,且两者能较好的诊断CHD。结论lncRNA H19、lncRNA CHAST为CHD发病的危险因素,可作为诊断CHD的血清指标,且二者联合诊断CHD的价值更高。 展开更多
关键词 冠心病 lncRNA H19 lncRNA CHAST
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Metaphor Analysis Based on Image Schema——Take the Poem Jie Fu Yin and its English Translation as an Example
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作者 程中芳 《海外英语》 2015年第4期180-182,共3页
There are many implied metaphors in the poetry of Tang dynasty. In this paper, the poem Reply of a Chaste Wife and its English version are analyzed through the image schema theory to explore the explanatory power of i... There are many implied metaphors in the poetry of Tang dynasty. In this paper, the poem Reply of a Chaste Wife and its English version are analyzed through the image schema theory to explore the explanatory power of image schema to the poems of Tang dynasty.At the same time, a new perspective to the appreciation of the metaphors in the poems of Tang dynasty is provided. 展开更多
关键词 cognitive LINGUISTICS image schema METAPHOR REPLY of a chaste WIFE
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Shen Queying: A Reform Martyr's Widow or a Martyress of Her Own Causes?
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作者 Nanxiu QIAN 《Frontiers of Literary Studies in China-Selected Publications from Chinese Universities》 2018年第2期254-280,共27页
The late Qing woman poet Shen queying (1877-19oo) had lived in the shadow of her husband, the reform martyr Lin Xu (1875-98). This paper subverts the conventional portrayal of Shen queying as a chaste widow throug... The late Qing woman poet Shen queying (1877-19oo) had lived in the shadow of her husband, the reform martyr Lin Xu (1875-98). This paper subverts the conventional portrayal of Shen queying as a chaste widow through reading her poems and song-lyrics in comparison with the poetic works of Lin Xu, to show that she herself was a reformer in her own right, and in this she was Lin Xu's vocal soul-mate rather than his mute wife and then widow. In her poems and song-lyrics, Shen Queying made clear that she had endeavored in poetic learning for expressing "the grand ambition of a racing steed," and her poetry sent unmistakable message to become a political player herself in China's reform era, fighting for the welfare of the country and the people. For some subtle reasons, however, she was not able to fulfill this ambition by personally participating in the reform activities. Frustrated, she resolved to be a supporter and protector of her husband. Precisely because Shen queying had put so much of her reform ideal into her husband's career, the execution of Lin Xu fell on her as a double blow. Her pining away to death, although conforming to a seemingly late imperial lien^J model, transcends this traditional image and bears a clear mark of the reform era, when a woman tied her personal life closely to the destiny of the country and the people. 展开更多
关键词 Shen Queying Lin Xu Hundred Days' Reform chaste widow women's poetry
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