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Life Time Attributable Cancer Risk Estimated Using Scanner Reported Dose Length Product during Chest Computed Tomography Imaging in Young Children
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作者 Mousa Bakkari Khaled Soliman +3 位作者 Abdullah Alrushoud Marwan Fahad Alosaimi Hanaa Alsheikh Abdelwahed Alhejaili 《Open Journal of Radiology》 2024年第2期74-82,共9页
This study aims to estimate the lifetime attributable cancer risk (LAR) for pediatric chest computed tomography (CT) examinations in five age groups using recently published age and region-specific conversion coeffici... This study aims to estimate the lifetime attributable cancer risk (LAR) for pediatric chest computed tomography (CT) examinations in five age groups using recently published age and region-specific conversion coefficients multiplying the widely available scanner registered dose length products (DLP) displayed on the CT console and hence calculating the Effective Dose (ED). The ED is then multiplied by the International Commission on Radiological Protection (ICRP) published risk factor for LAR. The obtained LAR values are compared with the international literature. Factors that may affect the LAR value are reported and discussed. The study included one hundred twenty five chest CT examinations for both males and females aged from less than one year to fifteen years. The patients reported data are from one single medical institution and using two CT scanners from June 2022 to December 2023. The results of this study may serve as benchmark for institutional radiation dose reference levels and risk estimation. 展开更多
关键词 Cancer Risk LAR chest CT Pediatric Radiology Radiation Dose DLP
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Comparison of efficacy of lung ultrasound and chest X-ray in diagnosing pulmonary edema and pleural effusion in ICU patients: A single centre, prospective, observational study
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作者 Kunal Tewari Sumanth Pelluru +5 位作者 Deepak Mishra Nitin Pahuja Akash Ray Mohapatra Jyotsna Sharma Om Bahadur Thapa Manjot Multani 《Open Journal of Anesthesiology》 2024年第3期41-50,共10页
Background and Aims While chest X-ray (CXR) has been a conventional tool in intensive care units (ICUs) to identify lung pathologies, computed tomography (CT) scan remains the gold standard. Use of lung ultrasound (LU... Background and Aims While chest X-ray (CXR) has been a conventional tool in intensive care units (ICUs) to identify lung pathologies, computed tomography (CT) scan remains the gold standard. Use of lung ultrasound (LUS) in resource-rich ICUs is still under investigation. The present study compares the utility of LUS to that of CXR in identifying pulmonary edema and pleural effusion in ICU patients. In addition, consolidation and pneumothorax were analyzed as secondary outcome measures. Material and Methods This is a prospective, single centric, observational study. Patients admitted in ICU were examined for lung pathologies, using LUS by a trained intensivist;and CXR done within 4 hours of each other. The final diagnosis was ascertained by an independent senior radiologist, based on the complete medical chart including clinical findings and the results of thoracic CT, if available. The results were compared and analyzed. Results Sensitivity, specificity and diagnostic accuracy of LUS was 95%, 94.4%, 94.67% for pleural effusion;and 98.33%, 97.78%, 98.00% for pulmonary edema respectively. Corresponding values with CXR were 48.33%, 76.67%, 65.33% for pleural effusion;and 36.67%, 82.22% and 64.00% for pulmonary edema respectively. Sensitivity, specificity and diagnostic accuracy of LUS was 91.30%, 96.85%, 96.00% for consolidation;and 100.00%, 79.02%, 80.00% for pneumothorax respectively. Corresponding values with CXR were 60.87%, 81.10%, 78.00% for consolidation;and 71.3%, 97.20%, 96.00% for pneumothorax respectively. Conclusion LUS has better diagnostic accuracy in diagnosis of pleural effusion and pulmonary edema when compared with CXR and is thus recommended as an effective alternative for diagnosis of these conditions in acute care settings. Our study recommends that a thoracic CT scan can be avoided in most of such cases. 展开更多
关键词 chest X ray (CXR) CONSOLIDATION Pulmonary edema Pleural effusion Lung ultrasound (LUS) PNEUMOTHORAX
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Pulmonary Edema and Pleural Effusion Detection Using Efficient Net-V1-B4 Architecture and AdamW Optimizer from Chest X-Rays Images
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作者 Anas AbuKaraki Tawfi Alrawashdeh +4 位作者 Sumaya Abusaleh Malek Zakarya Alksasbeh Bilal Alqudah Khalid Alemerien Hamzah Alshamaseen 《Computers, Materials & Continua》 SCIE EI 2024年第7期1055-1073,共19页
This paper presents a novelmulticlass systemdesigned to detect pleural effusion and pulmonary edema on chest Xray images,addressing the critical need for early detection in healthcare.A new comprehensive dataset was f... This paper presents a novelmulticlass systemdesigned to detect pleural effusion and pulmonary edema on chest Xray images,addressing the critical need for early detection in healthcare.A new comprehensive dataset was formed by combining 28,309 samples from the ChestX-ray14,PadChest,and CheXpert databases,with 10,287,6022,and 12,000 samples representing Pleural Effusion,Pulmonary Edema,and Normal cases,respectively.Consequently,the preprocessing step involves applying the Contrast Limited Adaptive Histogram Equalization(CLAHE)method to boost the local contrast of the X-ray samples,then resizing the images to 380×380 dimensions,followed by using the data augmentation technique.The classification task employs a deep learning model based on the EfficientNet-V1-B4 architecture and is trained using the AdamW optimizer.The proposed multiclass system achieved an accuracy(ACC)of 98.3%,recall of 98.3%,precision of 98.7%,and F1-score of 98.7%.Moreover,the robustness of the model was revealed by the Receiver Operating Characteristic(ROC)analysis,which demonstrated an Area Under the Curve(AUC)of 1.00 for edema and normal cases and 0.99 for effusion.The experimental results demonstrate the superiority of the proposedmulti-class system,which has the potential to assist clinicians in timely and accurate diagnosis,leading to improved patient outcomes.Notably,ablation-CAM visualization at the last convolutional layer portrayed further enhanced diagnostic capabilities with heat maps on X-ray images,which will aid clinicians in interpreting and localizing abnormalities more effectively. 展开更多
关键词 Image classification decision support system EfficientNet-V1-B4 AdamW optimizer pulmonary edema pleural effusion chest X-rays
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Relationship between neonatal respiratory distress syndrome pulmonary ultrasonography and respiratory distress score,oxygenation index,and chest radiography grading
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作者 Hai Yang Li-Jun Gao +5 位作者 Jing Lei Qiang Li Liu Cui Xiao-Hua Li Wu-Xuan Yin Sen-Hua Tian 《World Journal of Clinical Cases》 SCIE 2024年第20期4154-4165,共12页
BACKGROUND Accurate condition assessment is critical for improving the prognosis of neonatal respiratory distress syndrome(RDS),but current assessment methods for RDS pose a cumulative risk of harm to neonates.Thus,a ... BACKGROUND Accurate condition assessment is critical for improving the prognosis of neonatal respiratory distress syndrome(RDS),but current assessment methods for RDS pose a cumulative risk of harm to neonates.Thus,a less harmful method for assessing the health of neonates with RDS is needed.AIM To analyze the relationships between pulmonary ultrasonography and respiratory distress scores,oxygenation index,and chest X-ray grade of neonatal RDS to identify predictors of neonatal RDS severity.METHODS This retrospective study analyzed the medical information of 73 neonates with RDS admitted to the neonatal intensive care unit of Liupanshui Maternal and Child Care Service Center between April and December 2022.The pulmonary ultrasonography score,respiratory distress score,oxygenation index,and chest Xray grade of each newborn before and after treatment were collected.Spearman correlation analysis was performed to determine the relationships among these values and neonatal RDS severity.RESULTS The pulmonary ultrasonography score,respiratory distress score,oxygenation index,and chest X-ray RDS grade of the neonates were significantly lower after treatment than before treatment(P<0.05).Spearman correlation analysis showed that before and after treatment,the pulmonary ultrasonography score of neonates with RDS was positively correlated with the respiratory distress score,oxygenation index,and chest X-ray grade(ρ=0.429–0.859,P<0.05).Receiver operating characteristic curve analysis indicated that pulmonary ultrasonography screening effectively predicted the severity of neonatal RDS(area under the curve=0.805–1.000,P<0.05).CONCLUSION The pulmonary ultrasonography score was significantly associated with the neonatal RDS score,oxygenation index,and chest X-ray grade.The pulmonary ultrasonography score was an effective predictor of neonatal RDS severity. 展开更多
关键词 Neonatal respiratory distress syndrome Pulmonary ultrasonography Ultrasonography score Respiratory distress score Oxygenation index chest X-ray grading
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Chest Radiography: General Practitioners’ Compliance with Recommendations
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作者 Milckisédek Judicaël Marouruana Some Aïda Ida Tankoano +3 位作者 Pakisba Ali Ouedraogo Bassirou Kindo Nina-Astrid Ouedraogo Mohammed Ali Harchaoui 《Open Journal of Medical Imaging》 2024年第2期56-63,共8页
Introduction: Chest radiography is the most frequently prescribed imaging test in general practice in France. We aimed to assess the extent to which general practitioners follow the recommendations of the French Natio... Introduction: Chest radiography is the most frequently prescribed imaging test in general practice in France. We aimed to assess the extent to which general practitioners follow the recommendations of the French National Authority for Health in prescribing chest radiography. Methodology: We conducted a retrospective analysis study, in two radiology centers belonging to the same group in Saint-Omer and Aire-sur-la-Lys, of requests for chest radiography sent by general practitioners over the winter period between December 22, 2013, and March 21, 2014, for patients aged over 18 years. Results: One hundred and seventy-seven requests for chest X-rays were analyzed, 71.75% of which complied with recommendations. The most frequent reason was the search for bronchopulmonary infection, accounting for 70.08% of prescriptions, followed by 11.2% for requests to rule out pulmonary neoplasia, whereas the latter reason did not comply with recommendations. Chest X-rays contributed to a positive diagnosis in 28.81% of cases. The positive diagnosis was given by 36.22% of the recommended chest X-rays, versus 10% for those not recommended. Conclusion: In most cases, general practitioners follow HAS recommendations for prescribing chest X-rays. Non-recommended chest X-rays do not appear to make a major contribution to diagnosis or patient management, confirming the value of following the recommendations of the French National Authority for Health. 展开更多
关键词 chest X-Ray RECOMMENDATIONS General Practitioners PRESCRIPTION
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Rib Osteosynthesis for Sub-Acute Management of a Flail Chest in a Tertiary Centre in a Low-Middle Income Country of Sub-Saharan Africa: Case Report at Douala Laquintinie Hospital
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作者 Fabrice Stéphane Arroye Betou Nyankoue Mebouinz Ferdinand +11 位作者 Guy Aristide Bang Kobe Folkabo Zephany Banga Nkomo Douglas Moussa Seck Diop Abdoul Lahad Mbeng Marcella Derboise Christelle Biyouma Noel Essomba Souleyman Diatta Handy Eone Daniel Arthur Essomba Hassan Ndiaye Maurice Aurelien Sosso 《Open Journal of Thoracic Surgery》 2024年第1期1-16,共16页
Background: Costal fracture surgical is still a debate, therefore we shall select between early and delay surgical management. Case Report: We are reporting two cases of post road traffic clash delay ribs fractures os... Background: Costal fracture surgical is still a debate, therefore we shall select between early and delay surgical management. Case Report: We are reporting two cases of post road traffic clash delay ribs fractures osteosynthesis involving a 63-year-old man with multistage fractures on the left and pulmonary pinning of one of the costal arches, complicated by a homolateral haemothorax and a 41-year-old man with a bilateral flail chest. Conclusion: The simple postoperative course and the immediate postoperative improvement in the patient’s clinical respiratory condition enabled us to discuss the time frame for management, in this case the indication for early or later surgery. 展开更多
关键词 Flail chest Fixation Plate Rib Fracture OSTEOSYNTHESIS
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Impact of Optimizing Emergency Nursing Processes on Resuscitation Success in Patients with Acute Chest Pain
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作者 Xiaohan Chen 《Journal of Clinical and Nursing Research》 2024年第5期150-155,共6页
Objective:To analyze the effect of optimizing the emergency nursing process in the resuscitation of patients with acute chest pain and the impact on the resuscitation success rate.Methods:66 patients with acute chest ... Objective:To analyze the effect of optimizing the emergency nursing process in the resuscitation of patients with acute chest pain and the impact on the resuscitation success rate.Methods:66 patients with acute chest pain received by the emergency department of our hospital from January 2022 to December 2023 were selected as the study subjects and divided into two groups according to the differences in the emergency nursing process,i.e.,33 patients receiving routine emergency care were included in the control group,and 33 patients receiving the optimization of emergency nursing process intervention were included in the observation group.Patients’resuscitation effect and satisfaction with nursing care in the two groups were compared.Results:The observation group’s consultation assessment time,reception time,admission to the start of resuscitation time,and resuscitation time were shorter than that of the control group,the resuscitation success rate was higher than that of the control group,and the incidence of adverse events was lower than that of the control group,with statistically significant differences(P<0.05);and the observation group’s satisfaction with nursing care was higher than that of the control group,with statistically significant differences(P<0.05).Conclusion:Optimization of emergency nursing process intervention in the resuscitation of acute chest pain patients can greatly shorten the rescue time and improve the success rate of resuscitation,with higher patient satisfaction. 展开更多
关键词 chest pain Emergency resuscitation Optimization of emergency nursing process
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Application Value of NLR,PLR,LMR,HEART score,and POCT in Early Warning and Accurate Graded Diagnosis of High-Risk Chest Pain in Emergency Medicine
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作者 Shaochang Ma Chunhua Lin +2 位作者 Yanmei Li Yan Chen Guohui Zhang 《Journal of Clinical and Nursing Research》 2024年第4期93-98,共6页
Objective: To evaluate the application value of neutrophils/lymphocytes (NLR), platelets/lymphocytes (PLR), lymphocytes/monocytes (LMR), HEART (history, electrocardiogram, age, risk factors, and troponin) score, and p... Objective: To evaluate the application value of neutrophils/lymphocytes (NLR), platelets/lymphocytes (PLR), lymphocytes/monocytes (LMR), HEART (history, electrocardiogram, age, risk factors, and troponin) score, and point-of- care testing (POCT) in the early warning and precise diagnosis of high-risk chest pain in emergency medicine. Methods: A total of 157 patients with acute chest pain who were admitted to the emergency department and chest pain treatment unit of our hospital between August 2022 and September 2023 were selected. Rapid testing of bedside myocardial markers (ultrasensitive troponin (hs-cTnI), myoglobin (MYO), creatine kinase isoenzyme (CK-MB), D-dimer (D-Dimer), and N-terminal B-type natriuretic peptide precursor (NT-proBNP)) was performed on the patients using a POCT device (ThermoKing BioMQ60proB). A HEART score was used to classify the patients into low (n = 53), intermediate (n = 59), and high-risk (n = 45) groups, and the NLR, PLR, and LMR were calculated. The NLR, PLR, and LMR values were compared among the three groups of patients, and the optimal cutoff values as well as sensitivity and specificity were determined based on receiver operating characteristic (ROC) analysis. Results: The HEART scores of patients in the low-risk, intermediate-risk, and high-risk groups were (2.72 ± 0.24), (4.75 ± 0.56), and (5.32 ± 0.73) respectively, and the differences were statistically significant (P < 0.05). Compared with the low-risk group, the intermediate-risk group and high-risk group had a significantly higher NLR and PLR, and a significantly lower LMR;the high-risk group had higher NLR and PLR and lower values of LMR as compared to the other two groups, and the difference was statistically significant (P < 0.05). The ROC curves suggested that the area under the curve, sensitivity, and specificity of the combined diagnosis of NLR, PLR, LMR, HEART score, and POCT were greater than those of LR, PLR, and LMR with HEART score and POCT alone. Conclusion: The combined application of NLR, PLR, LMR, HEART score, and POCT has significant application value in the early warning and precise diagnosis of emergency high-risk chest pain. It provides a more simple, easy-to-access, and efficient assessment index for the clinical prediction and treatment of emergency high- risk chest pain. 展开更多
关键词 NLR PLR LMR POCT myocardial markers HEART score Emergency high-risk chest pain
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胃食管反流病误诊误治及防误诊与治疗对策
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作者 吕林 黄开月 +3 位作者 王凤云 马祥雪 吕咪 唐旭东 《临床误诊误治》 2025年第3期27-32,共6页
胃食管反流病(GERD)是消化科常见疾病,当患者以食管外症候群就诊时,易被误诊为慢性咳嗽、哮喘、慢性阻塞性肺疾病、冠心病心绞痛、慢性咽喉炎等,虽经相关治疗,效果不佳。GERD的临床症状涉及临床多个专科,当以食管外症状为主要表现甚至... 胃食管反流病(GERD)是消化科常见疾病,当患者以食管外症候群就诊时,易被误诊为慢性咳嗽、哮喘、慢性阻塞性肺疾病、冠心病心绞痛、慢性咽喉炎等,虽经相关治疗,效果不佳。GERD的临床症状涉及临床多个专科,当以食管外症状为主要表现甚至为唯一表现时,极易造成误诊、漏诊。本文分析了该病误诊误治现状及对策,旨在为临床医生在诊断该病时提供参考。 展开更多
关键词 胃食管反流 误诊 哮喘 胸痛 慢性咽喉炎 误治
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基于系统评价和网络药理学分析桂枝茯苓丸治疗冠心病的疗效及其抗动脉粥样硬化的作用机制
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作者 李京 王一名 +3 位作者 赵爽 刘子萌 张明雪 刘宁 《实用中医内科杂志》 2025年第1期1-5,I0001-I0006,共11页
目的运用系统评价对桂枝茯苓丸治疗胸痹心痛患者的疗效进一步确认,同时基于网络药理学考察桂枝茯苓丸对动脉粥样硬化可能作用机制。方法通过计算机检索2005—2023年中国知网(CNKI)、万方、维普及PubMed数据库中收录的关于桂枝茯苓丸治... 目的运用系统评价对桂枝茯苓丸治疗胸痹心痛患者的疗效进一步确认,同时基于网络药理学考察桂枝茯苓丸对动脉粥样硬化可能作用机制。方法通过计算机检索2005—2023年中国知网(CNKI)、万方、维普及PubMed数据库中收录的关于桂枝茯苓丸治疗胸痹心痛的随机对照试验(RCT)文献。经过纳入、排除及筛选标准,最终纳入9篇RCT文献,采用Cochrane协作网及Review Manager 5.1软件分析,同时运用网络药理学分析桂枝茯苓丸对动脉粥样硬化可能作用机制。结果心电图疗效Meta分析结果提示:Z=2.66(P<0.05),OR及95%CI为0.17(0.05,0.30),说明观察组的心电图有效率高于对照组。心绞痛Meta分析结果提示:Z=5.71(P<0.00001),OR及95%CI为4.70(2.76,7.99),说明观察组的心绞痛有效率高于对照组。临床总疗效Meta分析结果提示:Z=4.39(P=0.0001),OR及95%CI为5.31(2.52,11.19),说明观察组的临床总有效率高于对照组。网络药理学分析提示:桂枝茯苓丸治疗动脉粥样硬化的靶点和作用机制发现,FOS、IKBKB、MAPK8和RELA是核心靶点,作用通路包括流体剪切应力、TNF、凋亡或脂质通路。结论Meta分析证实桂枝茯苓丸可以提高胸痹心痛患者的心电图疗效、心绞痛疗效及临床总有效率,但由于纳入文献的质量偏低、未提及具体分组方式、是否盲法及不良反应,确切结论仍需要高质量文献支持;桂枝茯苓丸治疗动脉粥样硬化的靶点和作用机制发现,FOS、IKBKB、MAPK8和RELA是核心靶点,作用通路包括流体剪切应力、TNF、凋亡或脂质通路。 展开更多
关键词 桂枝茯苓丸 胸痹心痛 系统评价 网络药理学 动脉粥样硬化 作用机制
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基于边缘引导多阶段渐进式网络的胸片去噪研究
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作者 张健康 郑津津 +2 位作者 丰穗 苏天成 周洪军 《传感器与微系统》 北大核心 2025年第1期72-75,共4页
针对现有图像去噪方法对胸片去噪时对图像细节的复原程度不高的问题,基于边缘生成网络(Edge Net)和多阶段渐进式网络(MPRNet),提出一个端到端的边缘引导MPRNet。首先,利用边缘生成算法得到清晰胸片的边缘真值作为边缘先验输入网络;然后,... 针对现有图像去噪方法对胸片去噪时对图像细节的复原程度不高的问题,基于边缘生成网络(Edge Net)和多阶段渐进式网络(MPRNet),提出一个端到端的边缘引导MPRNet。首先,利用边缘生成算法得到清晰胸片的边缘真值作为边缘先验输入网络;然后,分3个阶段逐步对图像进行恢复,各阶段分别产生一个恢复图像;最终,将不同尺度得到的去噪结果进行融合。为证明网络的有效性,在公开的胸片数据集上进行了测试。结果表明:本文提出的算法在峰值信噪比(PSNR)和结构相似性(SSIM)指标上均超过了其他经典网络,而且能够在有效去除噪声的同时,保留更多细节。 展开更多
关键词 胸片 去噪 深度学习 边缘引导
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中医药防治PCI术后冠状动脉微循环障碍的研究进展
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作者 宋雨晴 符德玉 +4 位作者 周训杰 桂明泰 郑韫霆 王明珠 马玉龙 《中西医结合心脑血管病杂志》 2025年第2期233-237,共5页
经皮冠状动脉介入(PCI)是治疗冠心病的重要血运重建方式,但存在术后心绞痛反复发作的问题。现代医学多使用替罗非班、尼可地尔等药物或应用血栓抽吸等机械方法防治冠状动脉微循环障碍,然而不能达到满意疗效。中医药治疗冠状动脉微循环... 经皮冠状动脉介入(PCI)是治疗冠心病的重要血运重建方式,但存在术后心绞痛反复发作的问题。现代医学多使用替罗非班、尼可地尔等药物或应用血栓抽吸等机械方法防治冠状动脉微循环障碍,然而不能达到满意疗效。中医药治疗冠状动脉微循环障碍通过中药、针灸及功法等疗法,可显著缓解临床症状,改善冠状动脉微循环,提高生活质量。综述中医药治疗冠状动脉微循环障碍的研究进展,以期为中西医结合治疗冠状动脉微循环障碍提供诊疗思路。 展开更多
关键词 冠状动脉微循环障碍 经皮冠状动脉介入 胸痹心痛 综述
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毛德西教授加味大补心汤治疗胸痹心痛验案
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作者 张鸣 张文宗 +1 位作者 孟宁宁 毛德西 《中西医结合心脑血管病杂志》 2025年第2期318-320,共3页
胸痹心痛的发病与心脏功能失调密切相关,《黄帝内经》中“心为阳中之太阳”高度概括了心的发病特点。毛德西教授基于《黄帝内经》“心为阳中之太阳”理论自拟加味大补心汤治疗胸痹心痛(痰浊血瘀证),现总结毛德西教授治疗本病的临床经验。
关键词 胸痹心痛 痰浊血瘀 毛德西
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基于改进ResNet的多标签胸部X光图像分类
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作者 方燕燕 陈辉 《山东理工大学学报(自然科学版)》 CAS 2025年第2期1-9,共9页
针对目前胸部X光图像分类方法存在X光特异性特征表达不充分、高频图像特征提取效果差、疾病样本数量不平衡等问题,提出一种基于改进ResNet的多标签胸部X光图像分类方法(multi-label chest X-ray image classification based on improved... 针对目前胸部X光图像分类方法存在X光特异性特征表达不充分、高频图像特征提取效果差、疾病样本数量不平衡等问题,提出一种基于改进ResNet的多标签胸部X光图像分类方法(multi-label chest X-ray image classification based on improved ResNet, MLC-ResNet)。首先,设计一个多尺度特征提取和融合模块,以获取更丰富的特征信息;其次,将八度卷积替换为残差结构中的普通卷积,解决X光特异性特征表达不充分问题;再次,为改善高频特征提取效果,在ResNet中引入改进后的多层感知器(multilayer perception, MLP),更好地揭示图像的细节和整体结构,增加分类性能;最后,使用加权交叉熵损失函数增加样本数较少的类别权重,改善样本分布不平衡问题。在ChestX-Ray14和CheXpert数据集上进行实验测试,其平均AUC分别是0.858 7和0.844 7,相较于ResNet分类算法分别提高了4.47%和3.20%。通过与现有方法的对比实验,进一步证明MLC-ResNet模型具有更好的性能。 展开更多
关键词 多层感知器 ResNet 加权交叉熵损失函数 胸部X光图像
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从阳微阴弦论治老年难治性胃食管反流病胸痛
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作者 尹一丹 周正华 王威 《天津中医药》 2025年第2期175-178,共4页
难治性胃食管反流病胸痛在中医学上可归为“胸痹”范畴,《金匮要略》指出胸痹病因病机为阳微阴弦,在此基础上,根据阳微阴弦的病因病机,从心-脾-肾角度探讨老年难治性胃食管反流病胸痛的发生、发展、转归及治疗有重要指导意义。
关键词 老年难治性胃食管反流病 胸痛 阳微阴弦
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Local Recurrence of Low-Grade Myofibroblastic Sarcoma of the Chest Wall:Report of a Case and Literatures Review
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作者 吴捷 陈奇勋 朱慧能 《Chinese Journal of Clinical Oncology》 CSCD 2008年第1期72-74,共3页
Myofibroblastic sarcoma, composed primarily of myofibroblast, is a rare malignant tumor. Low-grade myofibroblastic sarcoma (LGMS) has been defined properly as a distinct entity in the 2002 WHO classification of soft... Myofibroblastic sarcoma, composed primarily of myofibroblast, is a rare malignant tumor. Low-grade myofibroblastic sarcoma (LGMS) has been defined properly as a distinct entity in the 2002 WHO classification of soft tissue tumors. Primary sarcoma of the chest wall is also a rare disease. This article describes a case of locally recurrent LGMS of the chest wall. 展开更多
关键词 myofibroblastic sarcoma chest wall recurrence.
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基于某车型Euro NCAP侧面柱碰胸压性能研究分析
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作者 周晓雷 董伟 +2 位作者 王刚刚 李文杰 王坤 《汽车实用技术》 2025年第1期90-96,共7页
文章基于某款新能源车型按欧盟新车评价规程(Euro NCAP)进行的整车安全性能开发,对侧柱碰工况的胸压问题进行的性能研究,通过胸压问题的理论研究得出影响因子,并采用有限元仿真分析、滑台试验和整车碰撞验证结合的研究方式,提出车身结... 文章基于某款新能源车型按欧盟新车评价规程(Euro NCAP)进行的整车安全性能开发,对侧柱碰工况的胸压问题进行的性能研究,通过胸压问题的理论研究得出影响因子,并采用有限元仿真分析、滑台试验和整车碰撞验证结合的研究方式,提出车身结构、气囊包型、座椅发泡设计等的优化方案,最终提升了整车碰撞安全性能。研究表明,乘员的安全空间、气囊对假人安全约束、座椅状态的稳定性等都对胸压性能产生影响,据此提出的方案最后通过实车碰撞试验验证了优化方案的可行性。 展开更多
关键词 侧柱碰 胸压性能 Euro NCAP 气囊 座椅
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桃仁红花煎中活血药与理气药配伍在防治胸痹中的应用研究
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作者 顾烜烨 张国勇 +2 位作者 周迎春 谢凌鹏 吴玉婷 《实用中医内科杂志》 2025年第1期31-33,共3页
“气为血之帅、血为气之母”,“气血”生理上相互依存,病理上相互影响。“气行则血行,气止则血止……气有一息之不运,则血有一息之不行”。故胸痹血瘀之证,常在活血祛瘀剂中配伍理气之品以助血行,既照顾了气血间“气行则血行”的生理关... “气为血之帅、血为气之母”,“气血”生理上相互依存,病理上相互影响。“气行则血行,气止则血止……气有一息之不运,则血有一息之不行”。故胸痹血瘀之证,常在活血祛瘀剂中配伍理气之品以助血行,既照顾了气血间“气行则血行”的生理关系,又顾及了气滞、血瘀、痰浊、寒邪等病邪于病理上的相互影响。文章从中医学血瘀在介导胸痹发病中的作用及“理气”法与“活血”法配伍在防治胸痹中的应用出发,探讨桃仁红花煎中活血药与理气药配伍在防治胸痹中的应用机制,并进一步阐释“理气活血”法配伍在防治胸痹中的科学内涵。 展开更多
关键词 桃仁红花煎 胸痹 活血法 理气法
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The chemical composition, quality control and pharmacological effects of Gualou-Xiebai-Banxia Decoction: a review
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作者 Yan-Tao Wang Yin-Yan Lai +4 位作者 Li Wang Xiao-Li Zheng Hong-Ju Li Su-Hong Chen Zheng Xiang 《Traditional Medicine Research》 2025年第4期72-82,共11页
Gualou-Xiebai-Banxia Decoction(GXBD)is a traditional Chinese herbal formula including four traditional Chinese medicines:Gualou(Trichosanthis Fructus,TF),Xiebai(Allii Macrostemonis Bulbus,AMB),Banxia(Pinelliae Rhizoma... Gualou-Xiebai-Banxia Decoction(GXBD)is a traditional Chinese herbal formula including four traditional Chinese medicines:Gualou(Trichosanthis Fructus,TF),Xiebai(Allii Macrostemonis Bulbus,AMB),Banxia(Pinelliae Rhizoma,PR)and yellow wine.It is a classical therapy for chest stuffiness and pain syndrome and is widely used in the clinical treatment of coronary heart disease.It also shows significant therapeutic effects on pulmonary heart disease,hyperlipidemia,and arrhythmia.This study conducted a literature review and collected information on GXBD from databases such as PubMed,Web of Science,China National Knowledge Infrastructure,and ScienceDirect.The result indicated that the main active ingredients of GXBD are steroids,flavonoids,terpenoids,alkaloids,amino acids,and organic acids.Trigonelline,macrostemonoside and cucurbitacin B can provide reference for its quality control.GXBD may exert therapeutic effects on coronary heart disease through AMPK,PI3K-AKT,oxLDL,VEGF,and NF-κB signal pathways.This review provides a comprehensive analysis and summary of the chemical composition and in vivo metabolism of three traditional Chinese medicines(TF,AMB,and PR),along with an evaluation of the chemical composition,quality control,pharmacological effects,and clinical application of GXBD.Based on these,areas requiring further research on GXBD have been proposed to provide a reference for its further development and new drug research. 展开更多
关键词 Gualou-Xiebai-Banxia Decoction chemical composition chest stuffiness quality control pharmacological mechanism
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基于“四位一体”理论探讨瓜蒌薤白半夏汤治疗经皮冠脉介入术后心绞痛
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作者 王春宝 王丹 +1 位作者 张龙 司国民 《山东中医杂志》 2025年第1期33-37,共5页
“四位一体”理论提供了一种从性、位、势、证四要素研究经方的新思路。本文先从“四位一体”理论出发,探析瓜蒌薤白半夏汤的性、位、势、证四要素:“方性”为寒温并用,合以辛温,佐以苦寒;“方位”为心胸连及背部;“方势”为散中有泻,... “四位一体”理论提供了一种从性、位、势、证四要素研究经方的新思路。本文先从“四位一体”理论出发,探析瓜蒌薤白半夏汤的性、位、势、证四要素:“方性”为寒温并用,合以辛温,佐以苦寒;“方位”为心胸连及背部;“方势”为散中有泻,以散为主;“方证”为阳微阴弦之胸阳不足、痰阻心脉证。在此基础上,再以“四位一体”理论阐释瓜蒌薤白半夏汤治疗经皮冠脉介入术后心绞痛的原理,并结合1则医案进行讨论分析。 展开更多
关键词 “四位一体”理论 瓜蒌薤白半夏汤 经皮冠脉介入术 心绞痛 胸痹 经方
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