BACKGROUND Many patients have inadequate long-term analgesia,respiratory distress,and hypoxemia due to a long-standing substantial smoking history or the presence of primary pulmonary diseases;analgesic treatment is n...BACKGROUND Many patients have inadequate long-term analgesia,respiratory distress,and hypoxemia due to a long-standing substantial smoking history or the presence of primary pulmonary diseases;analgesic treatment is not valid in these patients.Even if the imaging findings of rib fractures are relatively mild,rib fractures may cause severe position limitation,respiratory distress,and hypoxemia.AIM To investigate the curative effect of surgical treatment for patients with severe non-flail chest rib fractures.METHODS A total of 78 patients from our hospital with severe noncontinuous thoracic rib fractures from September 2016 to September 2018 were enrolled in our study.Thirty-nine patients underwent surgical treatment,and 39 underwent conservative treatment.The surgical treatment group received surgery performed with titanium plates,and the screws were inserted with open reduction and internal fixation.The conservative treatment group received analgesia and symptomatic treatment.The pain scores at 72 h,1 wk,2 wk,4 wk,6 wk,3 mo,and 6 mo were compared,and the SF-36 quality of life scores were compared atthe 3rd and 6th months.RESULTS Pain relief in the surgical group was significantly better than that in the conservative group at each time point(72 h,1 wk,2 wk,4 wk,6 wk,3 mo,and 6 mo after surgery,P<0.001).The SF-36 scores were significantly higher in the surgical group than in the conservative group at 1 mo and 6 mo(P<0.05).CONCLUSION Patients with severe non-flail chest rib fractures have a better quality of life following surgical treatment than following conservative treatment,and surgical treatment is also useful for relieving pain.We should pay more attention to the physiological functions and clinical manifestations of patients with severe rib fractures.In patients with non-flail chest rib fractures,surgical treatment is feasible and effective.展开更多
目的评估标准化急诊预检分诊模式在急诊胸痛患者中的应用效果。方法选择2023年2—5月福建省泉州市第一医院城东院区急诊科接诊的50例急性胸痛患者为对照组,2023年6—9月福建省泉州市第一医院城东院区急诊科接诊的50例急性胸痛患者为研...目的评估标准化急诊预检分诊模式在急诊胸痛患者中的应用效果。方法选择2023年2—5月福建省泉州市第一医院城东院区急诊科接诊的50例急性胸痛患者为对照组,2023年6—9月福建省泉州市第一医院城东院区急诊科接诊的50例急性胸痛患者为研究组。对照组采用传统急诊预检分诊方法,研究组采用基于改良早期预警评分系统(modified early warning score,MEWS)的标准化急诊预检分诊模式。比较2组患者急诊处理时间、急性冠脉综合征患者首次医疗接触到球囊开通时间(first medical contact to balloon,FMC-to-B)、进入医院大门至球囊开通时间(door to ballon,D-to-B)、不良事件发生情况。结果研究组预检分诊时间[(2.2±0.5)min vs.(3.6±1.4)min]、首份心电图时间[(6.1±1.9)min vs.(8.9±2.6)min]、床旁即时检测完成时间[(21.4±3.2)min vs.(30.6±6.8)min]、急诊科停留时间[(40.2±7.6)min vs.(54.6±11.8)min]均短于对照组(P<0.05)。研究组急性冠脉综合征患者FMC-to-B[(50.4±9.3)min vs.(71.3±14.7)min]与D-to-B[(78.6±11.7)min vs.(106.9±15.4)min]短于对照组(P<0.05)。研究组心力衰竭、休克、心律失常累计发生率低于对照组(10.0%vs.28.0%,P<0.05)。结论基于MEWS的标准化急诊预检分诊模式可提升急性胸痛救治效率,改善患者预后。展开更多
目的探讨宿迁地区基层胸痛中心发病至送达胸痛中心大门(symptom onset to door,StoD)时间的影响因素及对策。方法选择2022年1月—2023年6月宿迁市中西医结合医院胸痛中心收治的81例急性心肌梗死患者为研究对象。根据患者StoD时间分为≤...目的探讨宿迁地区基层胸痛中心发病至送达胸痛中心大门(symptom onset to door,StoD)时间的影响因素及对策。方法选择2022年1月—2023年6月宿迁市中西医结合医院胸痛中心收治的81例急性心肌梗死患者为研究对象。根据患者StoD时间分为≤6 h组50例与>6 h组31例。统计人口学资料以及相关影响因子,利用单因素分析与多因素logistic回归分析胸痛中心StoD时间的影响因素。结果2组疼痛程度评分、通过120入院还是自行来院、社区医生是否通过网络将心电图结果传输至胸痛中心、发病症状是否典型、家属态度是否积极、有无心血管疾病危险因素、是否夜间发病、发病地点与就诊医院的距离等指标比较,差异有统计学意义(P<0.05)。单因素分析及多因素logistic回归分析显示,自行来院、发病症状不典型、有心血管疾病危险因素、夜间发病、发病地点与就诊医院距离远均是胸痛中心StoD时间的危险因素,家属态度积极为保护因素(P<0.05)。结论基层胸痛中心StoD时间受患者来院途径、症状表现以及发病时间等影响,而家属积极态度有利于缩短StoD时间,需提高家属对疾病的认识,发挥区域诊疗中心协同救治的作用,缩短StoD时间及提高救治效率。展开更多
目的探究标准化急诊预检分诊模式在区域性胸痛中心中的应用价值。方法选取2020年7月—2022年1月陆军第七十三集团军医院未实施标准化急诊预检分诊模式时间段内接诊的100例急性胸痛患者设为对照组,将2022年2月—2023年6月陆军第七十三集...目的探究标准化急诊预检分诊模式在区域性胸痛中心中的应用价值。方法选取2020年7月—2022年1月陆军第七十三集团军医院未实施标准化急诊预检分诊模式时间段内接诊的100例急性胸痛患者设为对照组,将2022年2月—2023年6月陆军第七十三集团军医院开展标准化急诊预检分诊模式后接诊的100例急性胸痛患者为研究组。对比2组患者抢救指标、临床效果、急诊工作效率以及不良反应发生情况差异。结果研究组患者的预检分诊时间[(2.03±0.21)minvs.(3.05±0.29)min]、首份心电图时间[(5.06±1.01)minvs.(6.23±1.51)min]、开放静脉通路时间[(9.11±2.01)minvs.(11.63±2.01)min]、床旁测试(point-of-care-testing,POCT)+检验报告时间[(18.98±2.65)min vs.(23.65±2.81)min]均明显短于对照组(P<0.05)。研究组患者的首次医疗接触(first medical contact,FMC)至经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)(FMC-to-B)[(43.20±3.65)minvs.(56.96±5.18)min]、自送到医院至接受正规治疗总时间(total time from hospital to receiving formal treatment,D-to-B)[(72.36±6.23)min vs.(110.15±13.23)min]以及肌钙蛋白Ⅰ获得时间[(21.02±2.65)minvs.(31.05±3.11)min]均显著低于对照组(P<0.05)。研究组患者的急诊处置时间[(10.23±2.09)min vs.(16.32±3.01)min]以及急诊候诊时间[(0.98±0.31)min vs.(3.55±0.59)min]均明显短于对照组(P<0.05)。2组患者在预检分诊准确率比较,差异无统计学意义(P>0.05)。研究组患者出现心律失常1例,心力衰竭1例,不良反应总发生率为2.00%(2/100),显著低于对照组患者的9.00%(9/100)(P<0.05)。结论对急性胸痛患者开展标准化急诊预检分诊模式有助于提高患者预检分诊效率、改善临床治疗效果,对降低不良反应发生率具有积极意义。展开更多
Acute chest syndrome (ACS) is a leading cause of death from sickle cell disease worldwide accounting for about 25% of all deaths. The aim of this study was to determine the prevalence, clinical features and outcome in...Acute chest syndrome (ACS) is a leading cause of death from sickle cell disease worldwide accounting for about 25% of all deaths. The aim of this study was to determine the prevalence, clinical features and outcome in Port Harcourt, Nigeria. Materials and Methods: A retrospective cohort study during a five year period. Records of all patients with sickle cell anaemia (SCA) admitted into the Wards were examined. Those enrolled for the study satisfied two criteria: 1) lower respiratory tract symptoms and 2) new pulmonary infiltrates on the chest radiograph. Sociodemographics, genotype, clinical and laboratory features, treatment given and outcome were obtained. Data were analysed by descriptive statistics. Variables were compared by students’ t-test. P value ≤ 0.05 was regarded as significant. Results: A total of 345 children with sickle cell anaemia were admitted during the 5 year period. Twelve of them had acute chest syndrome (3.5%). Majority 7 (58.3%) of them were under 5 years. There were more males 8 (66.7%) than female 4 (33.3%). The most common clinical features were fever 12 (100%), cough 10 (83.3%), chest pain 5 (41.7%), pulmonary consolidation 12 (100%), and respiratory distress 12 (100%). The admitting diagnosis were bronchopneumonia 6 (50%), severe malaria 3 (25%) and vaso-occlusive crises 3 (25%). There were very high levels of leukocyte. Received ceftriaxone or ampicillin + gentamicin ± oral erythromycin), paracetamol 12 (100%), ibuprofen 8 (66.7%), tramadol 3 (25.0%), pentazocine 8 (66.7%) and blood transfusion 9 (75%). The average length of stay was 7 days (range 4 - 14 days). One patient died (8.3%). Conclusion: ACS is not uncommon in children with SCA in Port Harcourt. Education of parents on the need to recognize early symptoms of the disease is essential. Clinicians must be trained to correctly diagnose and manage it promptly and efficiently to avoid its related disastrous consequences.展开更多
Liver transplantation is a major abdominal operation and the intimate anatomic relation of the liver with the right hemidiaphragm predisposes the patient to various manifestations in the chest cavity.Furthermore,chron...Liver transplantation is a major abdominal operation and the intimate anatomic relation of the liver with the right hemidiaphragm predisposes the patient to various manifestations in the chest cavity.Furthermore,chronic liver disease affects pulmonary function before and after liver transplantation resulting in a considerable percentage of patients presenting with morbidity related to chest complications.This review aims to identify the potential chest complications of surgical interest during or after liver transplantation.Complications of surgical interest are defined as those conditions that necessitate an invasive procedure(such as thoracocentesis or a chest tube placement)in the chest or a surgical intervention performed by a thoracic surgeon.These complications will be classified as perioperative and postoperative;the latter will be categorized as early and late.Although thoracocentesis or a chest tube placement is usually sufficient when invasive measures are deemed necessary,in some patients,thoracic surgical interventions are warranted.A high index of suspicion is needed to recognize and treat these conditions promptly.A close collaboration between abdominal surgeons,intensive care unit physicians and thoracic surgeons is of paramount importance.展开更多
Rationale:Acute complications of cirrhosis can be life-threatening.One of the less common acute complications is hepatic hydrothorax whose medical management is rarely successful and is still controversial.Patient con...Rationale:Acute complications of cirrhosis can be life-threatening.One of the less common acute complications is hepatic hydrothorax whose medical management is rarely successful and is still controversial.Patient concerns:A 51-year-old patient presenting to the emergency room for a massive pleural effusion.Diagnosis:A hepatic hydrothorax with a placed chest tube whose removal was not possible.Interventions:Increased doses of diuretics with a strict salt-free diet.Outcomes:An improvement of the clinical state,with no recurrent pleural effusion up to one month.Lessons:Medical management of hepatic hydrothorax is possible.展开更多
Pulmonary alveolar microlithiasis(PAM)(MIM265100)is a rare disease characterized by the diffuse deposit of microlithiasis in alveolar spaces.PAM could occur worldwide with high prevalence in Asia and Europe.Familial o...Pulmonary alveolar microlithiasis(PAM)(MIM265100)is a rare disease characterized by the diffuse deposit of microlithiasis in alveolar spaces.PAM could occur worldwide with high prevalence in Asia and Europe.Familial occurrence indicates its autosomal recessive trait and the SLC34A2 gene was identified as the responsible gene for the disease.In spite of the versatile mutation sites in patients from other countries,exon 7and exon 8 might be the most liable gene in Chinese and Japanese patients.Most mutations caused the premature termination of proteins and produced truncated proteins,leading to the blocking of the recycling and degrading of outdated surfactant which is full of phospholipids.The most outstanding clinical feature of PAM is the discrepancy between the paucity of symptoms and the degree of pulmonary involvement.Diagnosis is easy to establish based on typical chest radiograph image and nuclear medicine improves its early diagnosis and active evaluation.Pathology of the unique intra-alveolar lamellar microliths gives strong support for diagnosis.No effective treatment is considered valid currently.However,lung transplantation is effective for advanced-stage patients,and long term treatment of disodium etidronate seems promising.展开更多
文摘BACKGROUND Many patients have inadequate long-term analgesia,respiratory distress,and hypoxemia due to a long-standing substantial smoking history or the presence of primary pulmonary diseases;analgesic treatment is not valid in these patients.Even if the imaging findings of rib fractures are relatively mild,rib fractures may cause severe position limitation,respiratory distress,and hypoxemia.AIM To investigate the curative effect of surgical treatment for patients with severe non-flail chest rib fractures.METHODS A total of 78 patients from our hospital with severe noncontinuous thoracic rib fractures from September 2016 to September 2018 were enrolled in our study.Thirty-nine patients underwent surgical treatment,and 39 underwent conservative treatment.The surgical treatment group received surgery performed with titanium plates,and the screws were inserted with open reduction and internal fixation.The conservative treatment group received analgesia and symptomatic treatment.The pain scores at 72 h,1 wk,2 wk,4 wk,6 wk,3 mo,and 6 mo were compared,and the SF-36 quality of life scores were compared atthe 3rd and 6th months.RESULTS Pain relief in the surgical group was significantly better than that in the conservative group at each time point(72 h,1 wk,2 wk,4 wk,6 wk,3 mo,and 6 mo after surgery,P<0.001).The SF-36 scores were significantly higher in the surgical group than in the conservative group at 1 mo and 6 mo(P<0.05).CONCLUSION Patients with severe non-flail chest rib fractures have a better quality of life following surgical treatment than following conservative treatment,and surgical treatment is also useful for relieving pain.We should pay more attention to the physiological functions and clinical manifestations of patients with severe rib fractures.In patients with non-flail chest rib fractures,surgical treatment is feasible and effective.
文摘目的评估标准化急诊预检分诊模式在急诊胸痛患者中的应用效果。方法选择2023年2—5月福建省泉州市第一医院城东院区急诊科接诊的50例急性胸痛患者为对照组,2023年6—9月福建省泉州市第一医院城东院区急诊科接诊的50例急性胸痛患者为研究组。对照组采用传统急诊预检分诊方法,研究组采用基于改良早期预警评分系统(modified early warning score,MEWS)的标准化急诊预检分诊模式。比较2组患者急诊处理时间、急性冠脉综合征患者首次医疗接触到球囊开通时间(first medical contact to balloon,FMC-to-B)、进入医院大门至球囊开通时间(door to ballon,D-to-B)、不良事件发生情况。结果研究组预检分诊时间[(2.2±0.5)min vs.(3.6±1.4)min]、首份心电图时间[(6.1±1.9)min vs.(8.9±2.6)min]、床旁即时检测完成时间[(21.4±3.2)min vs.(30.6±6.8)min]、急诊科停留时间[(40.2±7.6)min vs.(54.6±11.8)min]均短于对照组(P<0.05)。研究组急性冠脉综合征患者FMC-to-B[(50.4±9.3)min vs.(71.3±14.7)min]与D-to-B[(78.6±11.7)min vs.(106.9±15.4)min]短于对照组(P<0.05)。研究组心力衰竭、休克、心律失常累计发生率低于对照组(10.0%vs.28.0%,P<0.05)。结论基于MEWS的标准化急诊预检分诊模式可提升急性胸痛救治效率,改善患者预后。
文摘目的探究标准化急诊预检分诊模式在区域性胸痛中心中的应用价值。方法选取2020年7月—2022年1月陆军第七十三集团军医院未实施标准化急诊预检分诊模式时间段内接诊的100例急性胸痛患者设为对照组,将2022年2月—2023年6月陆军第七十三集团军医院开展标准化急诊预检分诊模式后接诊的100例急性胸痛患者为研究组。对比2组患者抢救指标、临床效果、急诊工作效率以及不良反应发生情况差异。结果研究组患者的预检分诊时间[(2.03±0.21)minvs.(3.05±0.29)min]、首份心电图时间[(5.06±1.01)minvs.(6.23±1.51)min]、开放静脉通路时间[(9.11±2.01)minvs.(11.63±2.01)min]、床旁测试(point-of-care-testing,POCT)+检验报告时间[(18.98±2.65)min vs.(23.65±2.81)min]均明显短于对照组(P<0.05)。研究组患者的首次医疗接触(first medical contact,FMC)至经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)(FMC-to-B)[(43.20±3.65)minvs.(56.96±5.18)min]、自送到医院至接受正规治疗总时间(total time from hospital to receiving formal treatment,D-to-B)[(72.36±6.23)min vs.(110.15±13.23)min]以及肌钙蛋白Ⅰ获得时间[(21.02±2.65)minvs.(31.05±3.11)min]均显著低于对照组(P<0.05)。研究组患者的急诊处置时间[(10.23±2.09)min vs.(16.32±3.01)min]以及急诊候诊时间[(0.98±0.31)min vs.(3.55±0.59)min]均明显短于对照组(P<0.05)。2组患者在预检分诊准确率比较,差异无统计学意义(P>0.05)。研究组患者出现心律失常1例,心力衰竭1例,不良反应总发生率为2.00%(2/100),显著低于对照组患者的9.00%(9/100)(P<0.05)。结论对急性胸痛患者开展标准化急诊预检分诊模式有助于提高患者预检分诊效率、改善临床治疗效果,对降低不良反应发生率具有积极意义。
文摘Acute chest syndrome (ACS) is a leading cause of death from sickle cell disease worldwide accounting for about 25% of all deaths. The aim of this study was to determine the prevalence, clinical features and outcome in Port Harcourt, Nigeria. Materials and Methods: A retrospective cohort study during a five year period. Records of all patients with sickle cell anaemia (SCA) admitted into the Wards were examined. Those enrolled for the study satisfied two criteria: 1) lower respiratory tract symptoms and 2) new pulmonary infiltrates on the chest radiograph. Sociodemographics, genotype, clinical and laboratory features, treatment given and outcome were obtained. Data were analysed by descriptive statistics. Variables were compared by students’ t-test. P value ≤ 0.05 was regarded as significant. Results: A total of 345 children with sickle cell anaemia were admitted during the 5 year period. Twelve of them had acute chest syndrome (3.5%). Majority 7 (58.3%) of them were under 5 years. There were more males 8 (66.7%) than female 4 (33.3%). The most common clinical features were fever 12 (100%), cough 10 (83.3%), chest pain 5 (41.7%), pulmonary consolidation 12 (100%), and respiratory distress 12 (100%). The admitting diagnosis were bronchopneumonia 6 (50%), severe malaria 3 (25%) and vaso-occlusive crises 3 (25%). There were very high levels of leukocyte. Received ceftriaxone or ampicillin + gentamicin ± oral erythromycin), paracetamol 12 (100%), ibuprofen 8 (66.7%), tramadol 3 (25.0%), pentazocine 8 (66.7%) and blood transfusion 9 (75%). The average length of stay was 7 days (range 4 - 14 days). One patient died (8.3%). Conclusion: ACS is not uncommon in children with SCA in Port Harcourt. Education of parents on the need to recognize early symptoms of the disease is essential. Clinicians must be trained to correctly diagnose and manage it promptly and efficiently to avoid its related disastrous consequences.
文摘Liver transplantation is a major abdominal operation and the intimate anatomic relation of the liver with the right hemidiaphragm predisposes the patient to various manifestations in the chest cavity.Furthermore,chronic liver disease affects pulmonary function before and after liver transplantation resulting in a considerable percentage of patients presenting with morbidity related to chest complications.This review aims to identify the potential chest complications of surgical interest during or after liver transplantation.Complications of surgical interest are defined as those conditions that necessitate an invasive procedure(such as thoracocentesis or a chest tube placement)in the chest or a surgical intervention performed by a thoracic surgeon.These complications will be classified as perioperative and postoperative;the latter will be categorized as early and late.Although thoracocentesis or a chest tube placement is usually sufficient when invasive measures are deemed necessary,in some patients,thoracic surgical interventions are warranted.A high index of suspicion is needed to recognize and treat these conditions promptly.A close collaboration between abdominal surgeons,intensive care unit physicians and thoracic surgeons is of paramount importance.
文摘Rationale:Acute complications of cirrhosis can be life-threatening.One of the less common acute complications is hepatic hydrothorax whose medical management is rarely successful and is still controversial.Patient concerns:A 51-year-old patient presenting to the emergency room for a massive pleural effusion.Diagnosis:A hepatic hydrothorax with a placed chest tube whose removal was not possible.Interventions:Increased doses of diuretics with a strict salt-free diet.Outcomes:An improvement of the clinical state,with no recurrent pleural effusion up to one month.Lessons:Medical management of hepatic hydrothorax is possible.
基金Supported by Zhejiang Provincial Science and Technology Project,No.2011C37073
文摘Pulmonary alveolar microlithiasis(PAM)(MIM265100)is a rare disease characterized by the diffuse deposit of microlithiasis in alveolar spaces.PAM could occur worldwide with high prevalence in Asia and Europe.Familial occurrence indicates its autosomal recessive trait and the SLC34A2 gene was identified as the responsible gene for the disease.In spite of the versatile mutation sites in patients from other countries,exon 7and exon 8 might be the most liable gene in Chinese and Japanese patients.Most mutations caused the premature termination of proteins and produced truncated proteins,leading to the blocking of the recycling and degrading of outdated surfactant which is full of phospholipids.The most outstanding clinical feature of PAM is the discrepancy between the paucity of symptoms and the degree of pulmonary involvement.Diagnosis is easy to establish based on typical chest radiograph image and nuclear medicine improves its early diagnosis and active evaluation.Pathology of the unique intra-alveolar lamellar microliths gives strong support for diagnosis.No effective treatment is considered valid currently.However,lung transplantation is effective for advanced-stage patients,and long term treatment of disodium etidronate seems promising.
