Seeing is an important index to evaluate the quality of an astronomical site.To estimate seeing at the Muztagh-Ata site with height and time quantitatively,the European Centre for Medium-Range Weather Forecasts reanal...Seeing is an important index to evaluate the quality of an astronomical site.To estimate seeing at the Muztagh-Ata site with height and time quantitatively,the European Centre for Medium-Range Weather Forecasts reanalysis database(ERA5)is used.Seeing calculated from ERA5 is compared consistently with the Differential Image Motion Monitor seeing at the height of 12 m.Results show that seeing decays exponentially with height at the Muztagh-Ata site.Seeing decays the fastest in fall in 2021 and most slowly with height in summer.The seeing condition is better in fall than in summer.The median value of seeing at 12 m is 0.89 arcsec,the maximum value is1.21 arcsec in August and the minimum is 0.66 arcsec in October.The median value of seeing at 12 m is 0.72arcsec in the nighttime and 1.08 arcsec in the daytime.Seeing is a combination of annual and about biannual variations with the same phase as temperature and wind speed indicating that seeing variation with time is influenced by temperature and wind speed.The Richardson number Ri is used to analyze the atmospheric stability and the variations of seeing are consistent with Ri between layers.These quantitative results can provide an important reference for a telescopic observation strategy.展开更多
This study explores the implementation of computed tomography(CT)reconstruction and simulation techniques for patient-specific valves,aiming to dissect the mechanical attributes of calcified valves within transcathete...This study explores the implementation of computed tomography(CT)reconstruction and simulation techniques for patient-specific valves,aiming to dissect the mechanical attributes of calcified valves within transcatheter heart valve replacement(TAVR)procedures.In order to facilitate this exploration,it derives pertinent formulas for 3D multi-material isogeometric hyperelastic analysis based on Hounsfield unit(HU)values,thereby unlocking foundational capabilities for isogeometric analysis in calcified aortic valves.A series of uniaxial and biaxial tensile tests is executed to obtain an accurate constitutive model for calcified active valves.To mitigate discretization errors,methodologies for reconstructing volumetric parametric models,integrating both geometric and material attributes,are introduced.Applying these analytical formulas,constitutive models,and precise analytical models to isogeometric analyses of calcified valves,the research ascertains their close alignment with experimental results through the close fit in displacement-stress curves,compellingly validating the accuracy and reliability of the method.This study presents a step-by-step approach to analyzing themechanical characteristics of patient-specific valves obtained fromCT images,holding significant clinical implications and assisting in the selection of treatment strategies and surgical intervention approaches in TAVR procedures.展开更多
To evaluate the safety of detergents,the toxicological test results of 580 collected detergents were analyzed.The results showed that,in the acute oral toxicity test,94.4%and 5.6%of the samples were classified as non-...To evaluate the safety of detergents,the toxicological test results of 580 collected detergents were analyzed.The results showed that,in the acute oral toxicity test,94.4%and 5.6%of the samples were classified as non-toxic and toxic respectively.In skin irritation test,95.1%of the samples were mild irritation or below,and 4.9%were moderate irritation or above.In the vaginal mucosa irritation test,79.0%of the samples were very mild irritation or below,while 21.0%were mild irritation or above.In the acute inhalation toxicity test,the proportion of the samples classified as actually non-toxic and toxic were 87.9%and 12.1%respectively.In the eye irritation test,95.7%of the samples belonged to mild irritation or below,and 4.3%of the samples belonged to moderate irritation or above.The products at risk in category A,B and C products account for 6.3%,7.7%and 14.2%respectively.Of the 580 tested samples,90.9%were relatively safe,while 9.1%were at risk.These data showed that most of the tested samples meet the safety requirements for use.展开更多
According to the daily precipitation data in artificial precipitation season during May to September from 1961 to 2008 in Liaoning Province,the maximum consecutive precipitation in the artificial precipitation test ar...According to the daily precipitation data in artificial precipitation season during May to September from 1961 to 2008 in Liaoning Province,the maximum consecutive precipitation in the artificial precipitation test area is studied based on the maximum consecutive precipitation from May to September in 48 years.The results shows that the period of maximum consecutive precipitation in each month is different,and the variance trends of maximum consecutive precipitation in May,July,August and September are decreasing,while the variance trend of maximum consecutive precipitation in June is increasing.展开更多
The effect of a variety of geometrics, initial conditions and material properties on the deformation behavior of thin films in the plane-strain bulge test was systematically scrutinized by performing the finite elemen...The effect of a variety of geometrics, initial conditions and material properties on the deformation behavior of thin films in the plane-strain bulge test was systematically scrutinized by performing the finite element analysis, and then the accuracy of the plane-strain bulge test in determining the mechanical properties of thin films in terms of our finite element results was analyzed. The results indicate that although the determination of the plane-strain modulus in the light of the plane-strain bulge equation is fairly accurate, the calculation of the residual stress is not satisfied as expected, especially for low residual stress. Finally, an approach is proposed for analyzing bulge test data, which will improve the accuracy and reliability of this bulge test technique.展开更多
Sperm function testing, once commonly performed for the infertile couple before employing assisted reproductive technology (ART), has fallen out of favour in many reproductive medicine centers throughout the world. ...Sperm function testing, once commonly performed for the infertile couple before employing assisted reproductive technology (ART), has fallen out of favour in many reproductive medicine centers throughout the world. Indeed, the most recent addition of the 'World Health Organisation (WHO) Laboratory Manual for the Examination and Processing of Hu- man Semen' now groups many of these procedures into a section termed Research Procedures. In large part, this reflects the current clinical practice of bypassing the in-depth evaluation of the male partner, while assuming that if a spermatozoon can be found for intracytoplasmic sperm injection (ICSI), it must be a healthy cell capable of achieving fertilization. Never- theless, sperm function testing can provide valuable clinical insights into defects causing male infertility. Admittedly, in some cases, functional sperm deficiencies can be overcome using an ART. In other cases, couples will be empowered by the knowledge of the cause of their infertility, and for some couples, perhaps even the likelihood of ICSI success (relative to the spermatozoa). The knowledge allows them to make truly informed reproductive decisions, including (perhaps) the de- cision to seek donor insemination, to adopt or to remain childless. Knowledge of the cause of their infertility may provide closure for couples and a sense of confidence regarding their choice of reproductive treatment.展开更多
This paper describes shaking table tests of a 1:12 scale model of a special concentrically braced steel frame with pinned connections, which was fabricated according to a one-bay braced frame selected from a typical ...This paper describes shaking table tests of a 1:12 scale model of a special concentrically braced steel frame with pinned connections, which was fabricated according to a one-bay braced frame selected from a typical main factory building of a large thermal power plant. In order to investigate the seismic performance of this type of structure, several ground motion accelerations with different levels for seismic intensity Ⅷ, based on the Chinese Code for Seismic Design of Buildings, were selected to excite the model. The results show that the design methods of the members and the connections are adequate and that the structural system will perform well in regions of high seismicity. In addition to the tests, numerical simulations were also conducted and the results showed good agreement with the test results. Thus, the numerical model is shown to be accurate and the beam element can be used to model this structural system.展开更多
Using wavelet analysis,regression analysis and the Mann-Kendall test,this paper analyzed time-series(1959-2006) weather data from 23 meteorological stations in an attempt to characterize the climate change in the Tari...Using wavelet analysis,regression analysis and the Mann-Kendall test,this paper analyzed time-series(1959-2006) weather data from 23 meteorological stations in an attempt to characterize the climate change in the Tarim River Basin of Xinjiang Uygur Autonomous Region,China.Major findings are as follows:1) In the 48-year study period,average annual temperature,annual precipitation and average annual relative humidity all presented nonlinear trends.2) At the 16-year time scale,all three climate indices unanimously showed a rather flat before 1964 and a detectable pickup thereafter.At the 8-year time scale,an S-shaped nonlinear and uprising trend was revealed with slight fluctuations in the entire process for all three indices.Incidentally,they all showed similar pattern of a slight increase before 1980 and a noticeable up-swing afterwards.The 4-year time scale provided a highly fluctuating pattern of periodical oscillations and spiral increases.3) Average annual relative humidity presented a negative correlation with average annual temperature and a positive correlation with annual precipitation at each time scale,which revealed a close dynamic relationship among them at the confidence level of 0.001.4) The Mann-Kendall test at the 0.05 confidence level demonstrated that the climate warming trend,as represented by the rising average annual temperature,was remarkable,but the climate wetting trend,as indicated by the rising annual precipitation and average annual relative humidity,was not obvious.展开更多
We used spatial, global trend and post-blocking analysis to examine the effectiveness of a progeny trial in a tree breeding program for Chinese fir (Cunninghamia lanceolata (Lamb.) Hook) on a hilly site with an en...We used spatial, global trend and post-blocking analysis to examine the effectiveness of a progeny trial in a tree breeding program for Chinese fir (Cunninghamia lanceolata (Lamb.) Hook) on a hilly site with an environmental gradient from hill top to bottom. Diameter at breast height (DBH) and tree height data had significant spatial auto-correlations among rows and columns. Adding a firstorder separable autoregressive term more effectively modelled the spatial variation than did the incomplete block (IB) model used for the experimental design. The spatial model also accounted for effects of experimental design factors and greatly reduced residual variances. The spatial analysis rel- ative to the IB analysis improved estimation of genetic parameters with the residual variance reduced 13 and 19% for DBH and tree height, respectively; heritability increased 35 and 51% for DBH and tree height, respectively; and genetic gain improved 3-5%. Fitting global trend and postblocking did not improve the analyses under IB model. The use of a spatial model or combined with a design model is recommended for forest genetic trials, particularly with global trend and local spatial variation of hilly sites.展开更多
A Monte Carlo experiment was done to create a statistically significant test table for selecting EOF modes whose signals are above the noise level. Numerical analysis showed that it is feasible to choose a shorter dat...A Monte Carlo experiment was done to create a statistically significant test table for selecting EOF modes whose signals are above the noise level. Numerical analysis showed that it is feasible to choose a shorter data set between temporal and spatial dimensions for conducting an EOF analysis, and thus simplify calculation of the covariance matrix and solution of its eigenvalues and eigenvectors. The experiment showed that the dominant EOF modes remained the same. This approach is more computationally efficient, reducing both computing time and computer memory requirement, while still retaining the dominant signal.展开更多
To avoid the serious accidents caused by the failure fastening bolts on reciprocating compressor cylinder cover,a new nondestructive testing(NDT) technology,metal magnetic memory(MMM) testing,was applied to safety eva...To avoid the serious accidents caused by the failure fastening bolts on reciprocating compressor cylinder cover,a new nondestructive testing(NDT) technology,metal magnetic memory(MMM) testing,was applied to safety evaluating and failure analyzing for the fastening bolts.Based on the dynamic stress calculation of the failure bolts,MMM testing was carried out at workshop.Given are the MMM stress distribution characteristics of the failure bolts and fracture faces.It has been found that the MMM signal variation amplitude of the crack transition zone in the fracture surface is minimal,that of the crack initiation zone is in the middle,and that of the tear fracture zone is maximal.The failure reasons were analyzed with MMM effect.The results of the metallographic examination showed that the validity and feasibility of MMM testing and failure analysis.This means MMM technology is a new,fast and validity method of failure analysis.展开更多
The over-load protective relay is widely used directly affects the safe running of a motor. The reliability for motor protection. The reliability of the over-load protective relay testing and reliability analysis of t...The over-load protective relay is widely used directly affects the safe running of a motor. The reliability for motor protection. The reliability of the over-load protective relay testing and reliability analysis of the over-load protective relay is an important way to improve the reliability of products. In this paper, the reliability test method of the over-load protective relay is studied, and the reliability tests of the typical products are carried out on a reliability tester developed by authors. In terms of the testing results, the reliability analysis is finished. The failure reasons are found and the measures are put forward to improve the reliability of the products.展开更多
Due to the large differences in physico-mechanical pro perties of composite strata,jamming,head sinking and other serious consequences occur frequently during tunnel boring machine(TBM)excavation.To analyse the stabil...Due to the large differences in physico-mechanical pro perties of composite strata,jamming,head sinking and other serious consequences occur frequently during tunnel boring machine(TBM)excavation.To analyse the stability of surrounding rocks in composite strata under the disturbance of TBM excavation,a geomechanical model test was carried out based on the Lanzhou water supply project.The evolution patterns and distribution characteristics of the strain,stress,and tunnel deformation and fracturing were analysed.The results showed that during TBM excavation in the horizontal composite formations(with upper soft and lower hard layers and with upper hard and lower soft layers),a significant difference in response to the surrounding rocks can be observed.As the strength ratio of the surrounding rocks decreases,the ratio of the maximum strain of the hard rock mass to that of the relatively soft rock mass gradually decreases.The radial stress of the relatively soft rock mass is smaller than that of the hard rock mass in both types of composite strata,indicating that the weak rock mass in the composite formation results in the difference in the mechanical behaviours of the surrounding rocks.The displacement field of the surrounding rocks obtained by the digital speckle correlation method(DSCM)and the macro-fracture morphology after tunnel excavation visually reflected the deformation difference of the composite rock mass.Finally,some suggestions and measures were provided for TBM excavation in composite strata,such as advance geological forecasting and effective monitoring of weak rock masses.展开更多
Selection of quantitative characteristics, division of their expression ranges, and selection of example varieties are key issues on developing DUS Test Guidelines, which are more crucial for quantitative characterist...Selection of quantitative characteristics, division of their expression ranges, and selection of example varieties are key issues on developing DUS Test Guidelines, which are more crucial for quantitative characteristics since their expressions vary in different degrees. Taking the development of DUS Test Guideline of Ranunculus asiaticus L. as an example, this paper applied statistic-based approaches for the analyses of quantitative characteristics. We selected 9 quantitative characteristics from 18 pre-selected characteristics, based on within-variety uniformity, stability between different growing cycles, and correlation among characteristics, by the analyses of coefficient of variation, paired-samples t-test and partial correlation. The expression ranges of the 9 selected quantitative characteristics were divided into different states using descriptive statistics and distribution frequency of varieties. Eight of the 9 selected quantitative characteristics were categorized as standard characteristics as they showed one peak in distribution frequency of 120 varieties in various expressions of the characteristics, whereas, plant height can be categorized as grouping characteristic since it gave two peaks, and can group the varieties into pot and cut varieties. Finally, box-plot was applied to visually select the example varieties, and varieties 7, 12, and 28 were determined as the example varieties for plant height. The methods described in this paper are effective for the selection of quantitative characteristics, division of expression ranges, and selection of example varieties in Ranunculus asiaticus L. for DUS test, and may also be interest for other plant genera.展开更多
This paper clarifies the essence of the significance test of singular value decomposition analysis (SVD), and investigates four rules for testing the significance of coupled modes of SVD, including parallel analysis...This paper clarifies the essence of the significance test of singular value decomposition analysis (SVD), and investigates four rules for testing the significance of coupled modes of SVD, including parallel analysis, nonparametric bootstrap, random-phase test, and a new rule named modified parallel analysis. A numerical experiment is conducted to quantitatively compare the performance of the four rules in judging whether a coupled mode of SVD is significant as parameters such as the sample size, the number of grid points, and the signal-to-noise ratio vary. The results show that the four rules perform better with lower ratio of the number of grid points to sample size. Modified parallel analysis and nonparametric bootstrap perform best to abandon the spurious coupled modes, but the latter is better than the former to retain the significant coupled modes when the sample size is not much larger than the number of grid points. Parallel analysis and random-phase test are robust to abandon the spurious coupled modes only when either (1) the observations at the grid points are spatially uncorrelated, or (2) the coupled signal is very strong for parallel analysis and is not weak for random-phase test. The reasons affecting the accuracy of the test rules are discussed.展开更多
Diabetes mellitus is a metabolic disease that is ranked among the top 10 causes of death by the world health organization.During the last few years,an alarming increase is observed worldwide with a 70%rise in the dise...Diabetes mellitus is a metabolic disease that is ranked among the top 10 causes of death by the world health organization.During the last few years,an alarming increase is observed worldwide with a 70%rise in the disease since 2000 and an 80%rise in male deaths.If untreated,it results in complications of many vital organs of the human body which may lead to fatality.Early detection of diabetes is a task of significant importance to start timely treatment.This study introduces a methodology for the classification of diabetic and normal people using an ensemble machine learning model and feature fusion of Chi-square and principal component analysis.An ensemble model,logistic tree classifier(LTC),is proposed which incorporates logistic regression and extra tree classifier through a soft voting mechanism.Experiments are also performed using several well-known machine learning algorithms to analyze their performance including logistic regression,extra tree classifier,AdaBoost,Gaussian naive Bayes,decision tree,random forest,and k nearest neighbor.In addition,several experiments are carried out using principal component analysis(PCA)and Chi-square(Chi-2)fea-tures to analyze the influence of feature selection on the performance of machine learning classifiers.Results indicate that Chi-2 features show high performance than both PCA features and original features.However,the highest accuracy is obtained when the proposed ensemble model LTC is used with the proposed fea-ture fusion framework-work which achieves a 0.85 accuracy score which is the highest of the available approaches for diabetes prediction.In addition,the statis-tical T-test proves the statistical significance of the proposed approach over other approaches.展开更多
AIM:To compare the costs and effectiveness of no screening and no eradication therapy, the population- based Helicobacter pylori (H pylori) serology screening with eradication therapy and 13C-Urea breath test (UBT) wi...AIM:To compare the costs and effectiveness of no screening and no eradication therapy, the population- based Helicobacter pylori (H pylori) serology screening with eradication therapy and 13C-Urea breath test (UBT) with eradication therapy. METHODS:A Markov model simulation was carried out in all 237 900 Chinese males with age between 35 and 44 from the perspective of the public healthcare provider in Singapore. The main outcome measures were the costs, number of gastric cancer cases prevented, life years saved, and quality-adjusted life years (QALYs) gained from screening age to death. The uncertainty surrounding the cost-effectiveness ratio was addressed by one-way sensitivity analyses. RESULTS:Compared to no screening, the incremental cost-effectiveness ratio (ICER) was $16 166 per life year saved or $13 571 per QALY gained for the serology screening, and $38 792 per life year saved and $32 525 per QALY gained for the UBT. The ICER was $477 079 per life year saved or $390 337 per QALY gained for the UBT compared to the serology screening. The cost- effectiveness of serology screening over the UBT was robust to most parameters in the model. CONCLUSION:The population-based serologyscreening for H pylori was more cost-effective than the UBT in prevention of gastric cancer in Singapore Chinese males.展开更多
Medical research on neurologic ailments requires representative animal models to validate treatments before they are translated to human clinical trials.Rodents are the predominant animal model used in neurological re...Medical research on neurologic ailments requires representative animal models to validate treatments before they are translated to human clinical trials.Rodents are the predominant animal model used in neurological research despite limited anatomic and physiologic similarities to humans.As a result,functional testing designed to assess locomotor recovery after neurologic impairment is well established in rodent models.Comparatively,large r,more clinically relevant models have not been as well studied.To achieve similar locomotor testing standardization in larger animals,the models must be accessible to a wide array of researchers.Non-human primates are the most relevant animal model fo r translational research,however ethical and financial barriers limit their accessibility.This review focuses on swine,sheep,and goats as large animal alternatives for transitional studies between rodents and non-human primates.The objective of this review is to compare motor testing and data collection methods used in swine,sheep,and goats to encourage testing standardization in these larger animal models.The PubMed database was analyzed by searching combinations of swine,sheep,and goats,neurologic injuries,and functional assessments.Findings were categorized by animal model,data collection method,and assessment design.Swine and sheep were used in the majority of the studies,while only two studies were found using goats.The functional assessments included open pen analysis,treadmill walking,and guided free walking.Data collection methods included subjective behavioral rating scales and objective tools such as pressure-sensitive mats and image-based analysis software.Overall,swine and sheep were well-suited for a variety of assessment designs,with treadmill walking and guided free walking offering the most consistency across multiple trials.Data collection methods varied,but image-based gait analysis software provided the most robust analysis.Future studies should be conducted to standardize functional testing methods after neurologic impairment in large animals.展开更多
To study the distribution law and random characteristics of casting defects in steel castings,24 civil engineering structural cast steel joints were divided into two groups:simple cast steel joints and complex cast st...To study the distribution law and random characteristics of casting defects in steel castings,24 civil engineering structural cast steel joints were divided into two groups:simple cast steel joints and complex cast steel joints.Three kinds of nondestructive testing(NDT)methods,namely,visual,magnetic particle,and ultrasonic inspections,were used to detect the macroscopic defects in joints.The NDT results were then statistically analyzed.The results show that the unfused core support is a common defect of complex cast steel joints,and the defect can be seen visually,so excavation and repair welding should be carried out before castings leave factories.Casting cracks are extremely likely to occur in the intersection area of tubes,which is called the ultrasonic inspection blind zone.The occurrence probability of gas pores on simple cast steel joints is the largest,and the occurrence probability of core support incomplete fusions on complex cast steel joints is the largest.However,when cast steel joints are counted as a whole sample,the occurrence probability of gas pores is larger than that of core support incomplete fusions.Therefore,it is the most common defect in cast steel joints.展开更多
A measure of the“goodness”or efficiency of the test suite is used to determine the proficiency of a test suite.The appropriateness of the test suite is determined through mutation analysis.Several Finite State Machi...A measure of the“goodness”or efficiency of the test suite is used to determine the proficiency of a test suite.The appropriateness of the test suite is determined through mutation analysis.Several Finite State Machine(FSM)mutants are produced in mutation analysis by injecting errors against hypotheses.These mutants serve as test subjects for the test suite(TS).The effectiveness of the test suite is proportional to the number of eliminated mutants.The most effective test suite is the one that removes the most significant number of mutants at the optimal time.It is difficult to determine the fault detection ratio of the system.Because it is difficult to identify the system’s potential flaws precisely.In mutation testing,the Fault Detection Ratio(FDR)metric is currently used to express the adequacy of a test suite.However,there are some issues with this metric.If both test suites have the same defect detection rate,the smaller of the two tests is preferred.The test case(TC)is affected by the same issue.The smaller two test cases with identical performance are assumed to have superior performance.Another difficulty involves time.The performance of numerous vehicles claiming to have a perfect mutant capture time is problematic.Our study developed three metrics to address these issues:FDR/|TS|,FDR/|TC|,and FDR/|Time|;In this context,most used test generation tools were examined and tested using the developed metrics.Thanks to the metrics we have developed,the research contributes to eliminating the problems related to performance measurement by integrating the missing parameters into the system.展开更多
基金funded by the National Natural Science Foundation of China(NSFC)the Chinese Academy of Sciences(CAS)(grant No.U2031209)the National Natural Science Foundation of China(NSFC,grant Nos.11872128,42174192,and 91952111)。
文摘Seeing is an important index to evaluate the quality of an astronomical site.To estimate seeing at the Muztagh-Ata site with height and time quantitatively,the European Centre for Medium-Range Weather Forecasts reanalysis database(ERA5)is used.Seeing calculated from ERA5 is compared consistently with the Differential Image Motion Monitor seeing at the height of 12 m.Results show that seeing decays exponentially with height at the Muztagh-Ata site.Seeing decays the fastest in fall in 2021 and most slowly with height in summer.The seeing condition is better in fall than in summer.The median value of seeing at 12 m is 0.89 arcsec,the maximum value is1.21 arcsec in August and the minimum is 0.66 arcsec in October.The median value of seeing at 12 m is 0.72arcsec in the nighttime and 1.08 arcsec in the daytime.Seeing is a combination of annual and about biannual variations with the same phase as temperature and wind speed indicating that seeing variation with time is influenced by temperature and wind speed.The Richardson number Ri is used to analyze the atmospheric stability and the variations of seeing are consistent with Ri between layers.These quantitative results can provide an important reference for a telescopic observation strategy.
基金supported by the Natural Science Foundation of China(Project Nos.52075340 and 61972011)the Shanghai Special Research Project on Aging Population and Maternal and Child Health(Project No.2020YJZX0106).
文摘This study explores the implementation of computed tomography(CT)reconstruction and simulation techniques for patient-specific valves,aiming to dissect the mechanical attributes of calcified valves within transcatheter heart valve replacement(TAVR)procedures.In order to facilitate this exploration,it derives pertinent formulas for 3D multi-material isogeometric hyperelastic analysis based on Hounsfield unit(HU)values,thereby unlocking foundational capabilities for isogeometric analysis in calcified aortic valves.A series of uniaxial and biaxial tensile tests is executed to obtain an accurate constitutive model for calcified active valves.To mitigate discretization errors,methodologies for reconstructing volumetric parametric models,integrating both geometric and material attributes,are introduced.Applying these analytical formulas,constitutive models,and precise analytical models to isogeometric analyses of calcified valves,the research ascertains their close alignment with experimental results through the close fit in displacement-stress curves,compellingly validating the accuracy and reliability of the method.This study presents a step-by-step approach to analyzing themechanical characteristics of patient-specific valves obtained fromCT images,holding significant clinical implications and assisting in the selection of treatment strategies and surgical intervention approaches in TAVR procedures.
文摘To evaluate the safety of detergents,the toxicological test results of 580 collected detergents were analyzed.The results showed that,in the acute oral toxicity test,94.4%and 5.6%of the samples were classified as non-toxic and toxic respectively.In skin irritation test,95.1%of the samples were mild irritation or below,and 4.9%were moderate irritation or above.In the vaginal mucosa irritation test,79.0%of the samples were very mild irritation or below,while 21.0%were mild irritation or above.In the acute inhalation toxicity test,the proportion of the samples classified as actually non-toxic and toxic were 87.9%and 12.1%respectively.In the eye irritation test,95.7%of the samples belonged to mild irritation or below,and 4.3%of the samples belonged to moderate irritation or above.The products at risk in category A,B and C products account for 6.3%,7.7%and 14.2%respectively.Of the 580 tested samples,90.9%were relatively safe,while 9.1%were at risk.These data showed that most of the tested samples meet the safety requirements for use.
文摘According to the daily precipitation data in artificial precipitation season during May to September from 1961 to 2008 in Liaoning Province,the maximum consecutive precipitation in the artificial precipitation test area is studied based on the maximum consecutive precipitation from May to September in 48 years.The results shows that the period of maximum consecutive precipitation in each month is different,and the variance trends of maximum consecutive precipitation in May,July,August and September are decreasing,while the variance trend of maximum consecutive precipitation in June is increasing.
基金Project(11172258)supported by the National Natural Science Foundation of China
文摘The effect of a variety of geometrics, initial conditions and material properties on the deformation behavior of thin films in the plane-strain bulge test was systematically scrutinized by performing the finite element analysis, and then the accuracy of the plane-strain bulge test in determining the mechanical properties of thin films in terms of our finite element results was analyzed. The results indicate that although the determination of the plane-strain modulus in the light of the plane-strain bulge equation is fairly accurate, the calculation of the residual stress is not satisfied as expected, especially for low residual stress. Finally, an approach is proposed for analyzing bulge test data, which will improve the accuracy and reliability of this bulge test technique.
文摘Sperm function testing, once commonly performed for the infertile couple before employing assisted reproductive technology (ART), has fallen out of favour in many reproductive medicine centers throughout the world. Indeed, the most recent addition of the 'World Health Organisation (WHO) Laboratory Manual for the Examination and Processing of Hu- man Semen' now groups many of these procedures into a section termed Research Procedures. In large part, this reflects the current clinical practice of bypassing the in-depth evaluation of the male partner, while assuming that if a spermatozoon can be found for intracytoplasmic sperm injection (ICSI), it must be a healthy cell capable of achieving fertilization. Never- theless, sperm function testing can provide valuable clinical insights into defects causing male infertility. Admittedly, in some cases, functional sperm deficiencies can be overcome using an ART. In other cases, couples will be empowered by the knowledge of the cause of their infertility, and for some couples, perhaps even the likelihood of ICSI success (relative to the spermatozoa). The knowledge allows them to make truly informed reproductive decisions, including (perhaps) the de- cision to seek donor insemination, to adopt or to remain childless. Knowledge of the cause of their infertility may provide closure for couples and a sense of confidence regarding their choice of reproductive treatment.
基金Northeast Electric Power Design Institute of China Under Grant No.K07-T716
文摘This paper describes shaking table tests of a 1:12 scale model of a special concentrically braced steel frame with pinned connections, which was fabricated according to a one-bay braced frame selected from a typical main factory building of a large thermal power plant. In order to investigate the seismic performance of this type of structure, several ground motion accelerations with different levels for seismic intensity Ⅷ, based on the Chinese Code for Seismic Design of Buildings, were selected to excite the model. The results show that the design methods of the members and the connections are adequate and that the structural system will perform well in regions of high seismicity. In addition to the tests, numerical simulations were also conducted and the results showed good agreement with the test results. Thus, the numerical model is shown to be accurate and the beam element can be used to model this structural system.
基金Under the auspices of the Second-stage Knowledge Innovation Programs of Chinese Academy of Sciences (No KZCX2-XB2-03,KZCX2-YW-127)National Natural Science Foundation of China (No 40671014)Shanghai Academic Discipline Project (Human Geography) (No B410)
文摘Using wavelet analysis,regression analysis and the Mann-Kendall test,this paper analyzed time-series(1959-2006) weather data from 23 meteorological stations in an attempt to characterize the climate change in the Tarim River Basin of Xinjiang Uygur Autonomous Region,China.Major findings are as follows:1) In the 48-year study period,average annual temperature,annual precipitation and average annual relative humidity all presented nonlinear trends.2) At the 16-year time scale,all three climate indices unanimously showed a rather flat before 1964 and a detectable pickup thereafter.At the 8-year time scale,an S-shaped nonlinear and uprising trend was revealed with slight fluctuations in the entire process for all three indices.Incidentally,they all showed similar pattern of a slight increase before 1980 and a noticeable up-swing afterwards.The 4-year time scale provided a highly fluctuating pattern of periodical oscillations and spiral increases.3) Average annual relative humidity presented a negative correlation with average annual temperature and a positive correlation with annual precipitation at each time scale,which revealed a close dynamic relationship among them at the confidence level of 0.001.4) The Mann-Kendall test at the 0.05 confidence level demonstrated that the climate warming trend,as represented by the rising average annual temperature,was remarkable,but the climate wetting trend,as indicated by the rising annual precipitation and average annual relative humidity,was not obvious.
基金funded by the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(Grant No.15KJA220002)Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)Fujian Province Science and Technology Research funding on the fourth Tree Breeding Cycle Program of Chinese fir(Grant No.Min Lin 2016-1)
文摘We used spatial, global trend and post-blocking analysis to examine the effectiveness of a progeny trial in a tree breeding program for Chinese fir (Cunninghamia lanceolata (Lamb.) Hook) on a hilly site with an environmental gradient from hill top to bottom. Diameter at breast height (DBH) and tree height data had significant spatial auto-correlations among rows and columns. Adding a firstorder separable autoregressive term more effectively modelled the spatial variation than did the incomplete block (IB) model used for the experimental design. The spatial model also accounted for effects of experimental design factors and greatly reduced residual variances. The spatial analysis rel- ative to the IB analysis improved estimation of genetic parameters with the residual variance reduced 13 and 19% for DBH and tree height, respectively; heritability increased 35 and 51% for DBH and tree height, respectively; and genetic gain improved 3-5%. Fitting global trend and postblocking did not improve the analyses under IB model. The use of a spatial model or combined with a design model is recommended for forest genetic trials, particularly with global trend and local spatial variation of hilly sites.
文摘A Monte Carlo experiment was done to create a statistically significant test table for selecting EOF modes whose signals are above the noise level. Numerical analysis showed that it is feasible to choose a shorter data set between temporal and spatial dimensions for conducting an EOF analysis, and thus simplify calculation of the covariance matrix and solution of its eigenvalues and eigenvectors. The experiment showed that the dominant EOF modes remained the same. This approach is more computationally efficient, reducing both computing time and computer memory requirement, while still retaining the dominant signal.
基金Sponsored by the National Natural Science Foundation of China (Grant No. 11072056)Natural Science Foundation of Heilongjiang Province of China(Grant No.A200907)Specialized Research Fund for the Doctoral Program of Higher Education (Grant No. 20092322120001)
文摘To avoid the serious accidents caused by the failure fastening bolts on reciprocating compressor cylinder cover,a new nondestructive testing(NDT) technology,metal magnetic memory(MMM) testing,was applied to safety evaluating and failure analyzing for the fastening bolts.Based on the dynamic stress calculation of the failure bolts,MMM testing was carried out at workshop.Given are the MMM stress distribution characteristics of the failure bolts and fracture faces.It has been found that the MMM signal variation amplitude of the crack transition zone in the fracture surface is minimal,that of the crack initiation zone is in the middle,and that of the tear fracture zone is maximal.The failure reasons were analyzed with MMM effect.The results of the metallographic examination showed that the validity and feasibility of MMM testing and failure analysis.This means MMM technology is a new,fast and validity method of failure analysis.
基金Project (No. E2005000039) supported by the Natural Science Foun-dation of Hebei Province, China
文摘The over-load protective relay is widely used directly affects the safe running of a motor. The reliability for motor protection. The reliability of the over-load protective relay testing and reliability analysis of the over-load protective relay is an important way to improve the reliability of products. In this paper, the reliability test method of the over-load protective relay is studied, and the reliability tests of the typical products are carried out on a reliability tester developed by authors. In terms of the testing results, the reliability analysis is finished. The failure reasons are found and the measures are put forward to improve the reliability of the products.
基金supported by the National Natural Science Foundation of China(Grant No.41941018)the National Program on Key Basic Research of China(973 Program)(Grant No.2014CB046902)The partial support from the Hubei Province Natural Science Foundation Innovation Group(Grant No.2018CFA013)。
文摘Due to the large differences in physico-mechanical pro perties of composite strata,jamming,head sinking and other serious consequences occur frequently during tunnel boring machine(TBM)excavation.To analyse the stability of surrounding rocks in composite strata under the disturbance of TBM excavation,a geomechanical model test was carried out based on the Lanzhou water supply project.The evolution patterns and distribution characteristics of the strain,stress,and tunnel deformation and fracturing were analysed.The results showed that during TBM excavation in the horizontal composite formations(with upper soft and lower hard layers and with upper hard and lower soft layers),a significant difference in response to the surrounding rocks can be observed.As the strength ratio of the surrounding rocks decreases,the ratio of the maximum strain of the hard rock mass to that of the relatively soft rock mass gradually decreases.The radial stress of the relatively soft rock mass is smaller than that of the hard rock mass in both types of composite strata,indicating that the weak rock mass in the composite formation results in the difference in the mechanical behaviours of the surrounding rocks.The displacement field of the surrounding rocks obtained by the digital speckle correlation method(DSCM)and the macro-fracture morphology after tunnel excavation visually reflected the deformation difference of the composite rock mass.Finally,some suggestions and measures were provided for TBM excavation in composite strata,such as advance geological forecasting and effective monitoring of weak rock masses.
基金supported by the Special Fund for Agroscientific Research in the Public Interest of Ministry of Agriculture,China(200903008-14)
文摘Selection of quantitative characteristics, division of their expression ranges, and selection of example varieties are key issues on developing DUS Test Guidelines, which are more crucial for quantitative characteristics since their expressions vary in different degrees. Taking the development of DUS Test Guideline of Ranunculus asiaticus L. as an example, this paper applied statistic-based approaches for the analyses of quantitative characteristics. We selected 9 quantitative characteristics from 18 pre-selected characteristics, based on within-variety uniformity, stability between different growing cycles, and correlation among characteristics, by the analyses of coefficient of variation, paired-samples t-test and partial correlation. The expression ranges of the 9 selected quantitative characteristics were divided into different states using descriptive statistics and distribution frequency of varieties. Eight of the 9 selected quantitative characteristics were categorized as standard characteristics as they showed one peak in distribution frequency of 120 varieties in various expressions of the characteristics, whereas, plant height can be categorized as grouping characteristic since it gave two peaks, and can group the varieties into pot and cut varieties. Finally, box-plot was applied to visually select the example varieties, and varieties 7, 12, and 28 were determined as the example varieties for plant height. The methods described in this paper are effective for the selection of quantitative characteristics, division of expression ranges, and selection of example varieties in Ranunculus asiaticus L. for DUS test, and may also be interest for other plant genera.
基金This work was supported by the National Natural Science Foundation of China under Grant No. 40233027.
文摘This paper clarifies the essence of the significance test of singular value decomposition analysis (SVD), and investigates four rules for testing the significance of coupled modes of SVD, including parallel analysis, nonparametric bootstrap, random-phase test, and a new rule named modified parallel analysis. A numerical experiment is conducted to quantitatively compare the performance of the four rules in judging whether a coupled mode of SVD is significant as parameters such as the sample size, the number of grid points, and the signal-to-noise ratio vary. The results show that the four rules perform better with lower ratio of the number of grid points to sample size. Modified parallel analysis and nonparametric bootstrap perform best to abandon the spurious coupled modes, but the latter is better than the former to retain the significant coupled modes when the sample size is not much larger than the number of grid points. Parallel analysis and random-phase test are robust to abandon the spurious coupled modes only when either (1) the observations at the grid points are spatially uncorrelated, or (2) the coupled signal is very strong for parallel analysis and is not weak for random-phase test. The reasons affecting the accuracy of the test rules are discussed.
基金supported by the Florida Center for Advanced Analytics and Data Science funded by Ernesto.Net(under the Algorithms for Good Grant).
文摘Diabetes mellitus is a metabolic disease that is ranked among the top 10 causes of death by the world health organization.During the last few years,an alarming increase is observed worldwide with a 70%rise in the disease since 2000 and an 80%rise in male deaths.If untreated,it results in complications of many vital organs of the human body which may lead to fatality.Early detection of diabetes is a task of significant importance to start timely treatment.This study introduces a methodology for the classification of diabetic and normal people using an ensemble machine learning model and feature fusion of Chi-square and principal component analysis.An ensemble model,logistic tree classifier(LTC),is proposed which incorporates logistic regression and extra tree classifier through a soft voting mechanism.Experiments are also performed using several well-known machine learning algorithms to analyze their performance including logistic regression,extra tree classifier,AdaBoost,Gaussian naive Bayes,decision tree,random forest,and k nearest neighbor.In addition,several experiments are carried out using principal component analysis(PCA)and Chi-square(Chi-2)fea-tures to analyze the influence of feature selection on the performance of machine learning classifiers.Results indicate that Chi-2 features show high performance than both PCA features and original features.However,the highest accuracy is obtained when the proposed ensemble model LTC is used with the proposed fea-ture fusion framework-work which achieves a 0.85 accuracy score which is the highest of the available approaches for diabetes prediction.In addition,the statis-tical T-test proves the statistical significance of the proposed approach over other approaches.
文摘AIM:To compare the costs and effectiveness of no screening and no eradication therapy, the population- based Helicobacter pylori (H pylori) serology screening with eradication therapy and 13C-Urea breath test (UBT) with eradication therapy. METHODS:A Markov model simulation was carried out in all 237 900 Chinese males with age between 35 and 44 from the perspective of the public healthcare provider in Singapore. The main outcome measures were the costs, number of gastric cancer cases prevented, life years saved, and quality-adjusted life years (QALYs) gained from screening age to death. The uncertainty surrounding the cost-effectiveness ratio was addressed by one-way sensitivity analyses. RESULTS:Compared to no screening, the incremental cost-effectiveness ratio (ICER) was $16 166 per life year saved or $13 571 per QALY gained for the serology screening, and $38 792 per life year saved and $32 525 per QALY gained for the UBT. The ICER was $477 079 per life year saved or $390 337 per QALY gained for the UBT compared to the serology screening. The cost- effectiveness of serology screening over the UBT was robust to most parameters in the model. CONCLUSION:The population-based serologyscreening for H pylori was more cost-effective than the UBT in prevention of gastric cancer in Singapore Chinese males.
文摘Medical research on neurologic ailments requires representative animal models to validate treatments before they are translated to human clinical trials.Rodents are the predominant animal model used in neurological research despite limited anatomic and physiologic similarities to humans.As a result,functional testing designed to assess locomotor recovery after neurologic impairment is well established in rodent models.Comparatively,large r,more clinically relevant models have not been as well studied.To achieve similar locomotor testing standardization in larger animals,the models must be accessible to a wide array of researchers.Non-human primates are the most relevant animal model fo r translational research,however ethical and financial barriers limit their accessibility.This review focuses on swine,sheep,and goats as large animal alternatives for transitional studies between rodents and non-human primates.The objective of this review is to compare motor testing and data collection methods used in swine,sheep,and goats to encourage testing standardization in these larger animal models.The PubMed database was analyzed by searching combinations of swine,sheep,and goats,neurologic injuries,and functional assessments.Findings were categorized by animal model,data collection method,and assessment design.Swine and sheep were used in the majority of the studies,while only two studies were found using goats.The functional assessments included open pen analysis,treadmill walking,and guided free walking.Data collection methods included subjective behavioral rating scales and objective tools such as pressure-sensitive mats and image-based analysis software.Overall,swine and sheep were well-suited for a variety of assessment designs,with treadmill walking and guided free walking offering the most consistency across multiple trials.Data collection methods varied,but image-based gait analysis software provided the most robust analysis.Future studies should be conducted to standardize functional testing methods after neurologic impairment in large animals.
基金The National Key R&D Program of China(No.2017YFC0805100)the National Natural Science Foundation of China(No.51578137)+1 种基金the Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutionsthe Open Research Fund Program of Jiangsu Key Laboratory of Engineering Mechanics。
文摘To study the distribution law and random characteristics of casting defects in steel castings,24 civil engineering structural cast steel joints were divided into two groups:simple cast steel joints and complex cast steel joints.Three kinds of nondestructive testing(NDT)methods,namely,visual,magnetic particle,and ultrasonic inspections,were used to detect the macroscopic defects in joints.The NDT results were then statistically analyzed.The results show that the unfused core support is a common defect of complex cast steel joints,and the defect can be seen visually,so excavation and repair welding should be carried out before castings leave factories.Casting cracks are extremely likely to occur in the intersection area of tubes,which is called the ultrasonic inspection blind zone.The occurrence probability of gas pores on simple cast steel joints is the largest,and the occurrence probability of core support incomplete fusions on complex cast steel joints is the largest.However,when cast steel joints are counted as a whole sample,the occurrence probability of gas pores is larger than that of core support incomplete fusions.Therefore,it is the most common defect in cast steel joints.
文摘A measure of the“goodness”or efficiency of the test suite is used to determine the proficiency of a test suite.The appropriateness of the test suite is determined through mutation analysis.Several Finite State Machine(FSM)mutants are produced in mutation analysis by injecting errors against hypotheses.These mutants serve as test subjects for the test suite(TS).The effectiveness of the test suite is proportional to the number of eliminated mutants.The most effective test suite is the one that removes the most significant number of mutants at the optimal time.It is difficult to determine the fault detection ratio of the system.Because it is difficult to identify the system’s potential flaws precisely.In mutation testing,the Fault Detection Ratio(FDR)metric is currently used to express the adequacy of a test suite.However,there are some issues with this metric.If both test suites have the same defect detection rate,the smaller of the two tests is preferred.The test case(TC)is affected by the same issue.The smaller two test cases with identical performance are assumed to have superior performance.Another difficulty involves time.The performance of numerous vehicles claiming to have a perfect mutant capture time is problematic.Our study developed three metrics to address these issues:FDR/|TS|,FDR/|TC|,and FDR/|Time|;In this context,most used test generation tools were examined and tested using the developed metrics.Thanks to the metrics we have developed,the research contributes to eliminating the problems related to performance measurement by integrating the missing parameters into the system.