To assess the impact of disease characteristics on the quality of life (QOL) in children with inflammatory bowel diseases (IBD).METHODSThis was a cross-sectional study conducted at the First Department of Pediatrics o...To assess the impact of disease characteristics on the quality of life (QOL) in children with inflammatory bowel diseases (IBD).METHODSThis was a cross-sectional study conducted at the First Department of Pediatrics of the University of Athens at the “Aghia Sophia” Children’s Hospital. Children diagnosed with Crohn’s disease (CD) or ulcerative colitis (UC), who were followed as outpatients or during a hospitalization, participated, after informed consent was obtained from their legal representative. QOL was assessed by the IMPACT-III questionnaire. Demographic data and disease characteristics were also collected. Statistical analyses included parametric (Student’s t-test and Pearson’s r) and non-parametric (Mann-Whitney test, Fisher’s test and Spearman’s rho) procedures.RESULTSNinety-nine patients (UC: 37, 73.0% females, CD: 62, 51.6% females), aged 12.8 ± 2.6 years were included. Overall, as well as, sub-domain scores did not differ between UC and CD (overall score: 73.9 ± 13.3 vs 77.5 ± 11.2, respectively, P = 0.16). In the entire sample, total score was related to physician’s global assessment (PGA, patients classified as “mild/moderate” active disease had, on average, 14.8 ± 2.7 points lower total scores compared to those “in remission”, P < 0.001) and age at IMPACT completion (Pearson’s r = 0.29, P = 0.05). Disease activity assessed by the indices Pediatric Ulcerative Colitis activity index, Pediatric Crohn’s disease activity index or PGA was significantly associated with all subdomains scores. Presence of extraintestinal manifestations had a negative impact on emotional and social functioning domains.CONCLUSIONDisease activity is the main correlate of QOL in children with IBD, underlining the importance of achieving and sustaining clinical remission展开更多
The World Children's Art Festival will be held in Shanghai from July 22 to 28 this year.The event will be sponsored by the China Welfare Institute,the Shanghai Association for Friendship with For-eign Countries an...The World Children's Art Festival will be held in Shanghai from July 22 to 28 this year.The event will be sponsored by the China Welfare Institute,the Shanghai Association for Friendship with For-eign Countries and the Shanghai Soong Ching Ling Foundation.The theme will be"Peace,Friendship and the Future,"and children's literary and art groups from across the world are welcome to take part.Participants can range between eight and 17 in age.Music and dance will be the main activities,and all performances must be national in character.展开更多
Henry David Thoreau was wholeheartedly in love with nature and he devoted almost all his life time to observation,appreciation and study of nature.Thus he formed a deep understanding of nature.In 1845,Thoreau began a ...Henry David Thoreau was wholeheartedly in love with nature and he devoted almost all his life time to observation,appreciation and study of nature.Thus he formed a deep understanding of nature.In 1845,Thoreau began a two-year and twomonth residence at Walden Pond.His life was lonely but full of fragrance.He wanted to live meaningfully,confront the essential facts of life and live a simple life.Based on the review of the literature related to this topic,this paper aims to study Henry David Thoreau’s spiritual world,especially reflected in his famous book—Walden.展开更多
Hypersphere World-Universe Model (WUM) is, in fact, a Paradigm Shift in Cosmology [1]. In this paper, we provide seven Pillars of WUM: Medium of the World;Inter-Connectivity of Primary Cosmological Parameters;Creation...Hypersphere World-Universe Model (WUM) is, in fact, a Paradigm Shift in Cosmology [1]. In this paper, we provide seven Pillars of WUM: Medium of the World;Inter-Connectivity of Primary Cosmological Parameters;Creation of Matter;Multicomponent Dark Matter;Macroobjects;Volcanic Rotational Fission;Dark Matter Reactors. We describe the evolution of the World from the Beginning up to the birth of the Solar System and discuss the condition of the Early Earth before the beginning of life on it.展开更多
This paper focuses on the fairytale style in Peter Pan which is James Matthew Barrie's masterpiece. This work belongs to fairytale and the protagonist who named Peter Pan never grows up. Through the analysis of Pe...This paper focuses on the fairytale style in Peter Pan which is James Matthew Barrie's masterpiece. This work belongs to fairytale and the protagonist who named Peter Pan never grows up. Through the analysis of Peter Pan and his little friends' experience in real world and Neverland, readers can know the fairytale style in Peter Pan. At the same time, this paper also points out the characterization of Peter pan reflected the writer's attitude to growing up and the fairytale style as bridge between the virtual world and the real world. It is the fairytale style that adds the artistic charm of Peter Pan.展开更多
文摘To assess the impact of disease characteristics on the quality of life (QOL) in children with inflammatory bowel diseases (IBD).METHODSThis was a cross-sectional study conducted at the First Department of Pediatrics of the University of Athens at the “Aghia Sophia” Children’s Hospital. Children diagnosed with Crohn’s disease (CD) or ulcerative colitis (UC), who were followed as outpatients or during a hospitalization, participated, after informed consent was obtained from their legal representative. QOL was assessed by the IMPACT-III questionnaire. Demographic data and disease characteristics were also collected. Statistical analyses included parametric (Student’s t-test and Pearson’s r) and non-parametric (Mann-Whitney test, Fisher’s test and Spearman’s rho) procedures.RESULTSNinety-nine patients (UC: 37, 73.0% females, CD: 62, 51.6% females), aged 12.8 ± 2.6 years were included. Overall, as well as, sub-domain scores did not differ between UC and CD (overall score: 73.9 ± 13.3 vs 77.5 ± 11.2, respectively, P = 0.16). In the entire sample, total score was related to physician’s global assessment (PGA, patients classified as “mild/moderate” active disease had, on average, 14.8 ± 2.7 points lower total scores compared to those “in remission”, P < 0.001) and age at IMPACT completion (Pearson’s r = 0.29, P = 0.05). Disease activity assessed by the indices Pediatric Ulcerative Colitis activity index, Pediatric Crohn’s disease activity index or PGA was significantly associated with all subdomains scores. Presence of extraintestinal manifestations had a negative impact on emotional and social functioning domains.CONCLUSIONDisease activity is the main correlate of QOL in children with IBD, underlining the importance of achieving and sustaining clinical remission
文摘The World Children's Art Festival will be held in Shanghai from July 22 to 28 this year.The event will be sponsored by the China Welfare Institute,the Shanghai Association for Friendship with For-eign Countries and the Shanghai Soong Ching Ling Foundation.The theme will be"Peace,Friendship and the Future,"and children's literary and art groups from across the world are welcome to take part.Participants can range between eight and 17 in age.Music and dance will be the main activities,and all performances must be national in character.
文摘Henry David Thoreau was wholeheartedly in love with nature and he devoted almost all his life time to observation,appreciation and study of nature.Thus he formed a deep understanding of nature.In 1845,Thoreau began a two-year and twomonth residence at Walden Pond.His life was lonely but full of fragrance.He wanted to live meaningfully,confront the essential facts of life and live a simple life.Based on the review of the literature related to this topic,this paper aims to study Henry David Thoreau’s spiritual world,especially reflected in his famous book—Walden.
文摘Hypersphere World-Universe Model (WUM) is, in fact, a Paradigm Shift in Cosmology [1]. In this paper, we provide seven Pillars of WUM: Medium of the World;Inter-Connectivity of Primary Cosmological Parameters;Creation of Matter;Multicomponent Dark Matter;Macroobjects;Volcanic Rotational Fission;Dark Matter Reactors. We describe the evolution of the World from the Beginning up to the birth of the Solar System and discuss the condition of the Early Earth before the beginning of life on it.
文摘This paper focuses on the fairytale style in Peter Pan which is James Matthew Barrie's masterpiece. This work belongs to fairytale and the protagonist who named Peter Pan never grows up. Through the analysis of Peter Pan and his little friends' experience in real world and Neverland, readers can know the fairytale style in Peter Pan. At the same time, this paper also points out the characterization of Peter pan reflected the writer's attitude to growing up and the fairytale style as bridge between the virtual world and the real world. It is the fairytale style that adds the artistic charm of Peter Pan.
