Both enantiomers R-1 and S-1 of a chiral C60 derivative were synthesized by the reactions of C60 with 1, 1'-bi-2-naphthol bis(azidoacetates) and characterized by FD-MS, fT-IR,1H NMR, 13C NMR, UV-VIS, CD spectra.
Organic photovoltaic devices(OPVs) using chiral cyclohexene-fused [C_(60)]-fullerene derivatives that have(l)-menthyl ester moiety have been prepared and their properties evaluated as acceptor molecules with P3 HT pol...Organic photovoltaic devices(OPVs) using chiral cyclohexene-fused [C_(60)]-fullerene derivatives that have(l)-menthyl ester moiety have been prepared and their properties evaluated as acceptor molecules with P3 HT polymer: racemic cyclohexene-fused [C_(60)] fullenene,(RS)-(1 R,2 S,5 R)-2 a showed higher PCE(2.81%) than that of standard [C_(60)]-PCBM(2.64%) under the same analysis conditions. On the contrary, devices using chiral(R)-(1 R,2 S,5 R)-2 a and(S)-(1 R,2 S,5 R)-2 a, showed PCE as 1.08% and 1.10%, respectively. The main origin of the differences in PCE was found to be their poor Jsc values. The results indicate that the aggregation state might influence the interaction state with P3 HT and impact the results of the OPV properties, Jsc values in particular.展开更多
Oxidative stress has been considered as a major cause of cellular injuries in a variety of clinical abnormalities, especially prominent in neural diseases. One of the usable ways to prevent the reactive oxygen species...Oxidative stress has been considered as a major cause of cellular injuries in a variety of clinical abnormalities, especially prominent in neural diseases. One of the usable ways to prevent the reactive oxygen species (ROS)-mediated cellular injury is dietary or pharmaceutical augmentation of some free radical scavenger. Water-soluble amino-fullerene is a novel compound that behaves as a free radical scavenger with excellent biology consistent. In the present study, we have synthesized and characterized a novel cystine C60 derivative for the first time, and investigated the effects on hydrogen peroxide-induced oxidative stress and apoptotic death in cultured rat pheochromocytoma (PC12) cells. PC12 cells treated with hydrogen peroxide underwent apoptotic death as determined by MTT, PI/Hoechst 33342 staining and flow cytometry analysis. These results suggested that cystine C60 derivative has the potential to prevent oxidative stress-induced cell death and has no evident toxicity.展开更多
文摘Both enantiomers R-1 and S-1 of a chiral C60 derivative were synthesized by the reactions of C60 with 1, 1'-bi-2-naphthol bis(azidoacetates) and characterized by FD-MS, fT-IR,1H NMR, 13C NMR, UV-VIS, CD spectra.
基金supported by a Grant-in-Aid for Scientific Research of the GSC Center of Tottori University from the Ministry of Education, Culture, Sports, Science and Technology of Japansupported by a fund for Environmental Research from Tottori Prefecture
文摘Organic photovoltaic devices(OPVs) using chiral cyclohexene-fused [C_(60)]-fullerene derivatives that have(l)-menthyl ester moiety have been prepared and their properties evaluated as acceptor molecules with P3 HT polymer: racemic cyclohexene-fused [C_(60)] fullenene,(RS)-(1 R,2 S,5 R)-2 a showed higher PCE(2.81%) than that of standard [C_(60)]-PCBM(2.64%) under the same analysis conditions. On the contrary, devices using chiral(R)-(1 R,2 S,5 R)-2 a and(S)-(1 R,2 S,5 R)-2 a, showed PCE as 1.08% and 1.10%, respectively. The main origin of the differences in PCE was found to be their poor Jsc values. The results indicate that the aggregation state might influence the interaction state with P3 HT and impact the results of the OPV properties, Jsc values in particular.
文摘Oxidative stress has been considered as a major cause of cellular injuries in a variety of clinical abnormalities, especially prominent in neural diseases. One of the usable ways to prevent the reactive oxygen species (ROS)-mediated cellular injury is dietary or pharmaceutical augmentation of some free radical scavenger. Water-soluble amino-fullerene is a novel compound that behaves as a free radical scavenger with excellent biology consistent. In the present study, we have synthesized and characterized a novel cystine C60 derivative for the first time, and investigated the effects on hydrogen peroxide-induced oxidative stress and apoptotic death in cultured rat pheochromocytoma (PC12) cells. PC12 cells treated with hydrogen peroxide underwent apoptotic death as determined by MTT, PI/Hoechst 33342 staining and flow cytometry analysis. These results suggested that cystine C60 derivative has the potential to prevent oxidative stress-induced cell death and has no evident toxicity.
