Two Chiral Building Blocks for the Stereocontrolled Synthesis of Anti-and Syn-1,3-Diols

Two chiral building blocks 1 and 2 for anti-and syn-1, 3-diols has been achieved in 8 steps and 7 steps respectively, starting from the readily available and inexpensive D (+)-xylose 3.

Synthesis of an Anti-1,3-Diol Type Chiral Building Block

A chiral building block, anti-1,3-diol 2, has been synthesized in 7 steps, starting from readily available and inexpensive D-(+)-xylose.

Synthesis of （-）-Harzialactone A from a Readily Accessible Epoxy Chiral Building Block

The antipode of （＋）-harzialactone A, an antitumor marine metabolite, was synthesized with the two stereogenic centers in the target structure taken from an optically active epoxy cbiral building block.

Facile and Efficient Synthesis of （R）-4-（Benzyloxy）-3- methylbutanenitrile： Toward Developing a Versatile Chiral Building Block

A practical synthesis of （R）-4-（benzyloxy）-3-methylbutanenitrile, a potential chiral building block, from the corresponding a-keto ester in high yield and large scale was presented.

On the Absolute Configuration of Schweinfurthinol

Through the chiral-pool based synthesis of both enantiomers of schweinfurthinol, it has been proven that this natural product isolated from the seeds of Canarium schweinfurthii possesses an （S） configuration. The optical rotation data for pure schweinfurthinol is also updated.

Synthesis of an Antitumoral Diarylheptanoid Containing 1,3-Diol Functionality

A bioactive derivative of a natural diarylheptanoid containing a 1,3-anti diol motif was synthesized with the oxygen-carrying stereogenic centers taken from an enantiopure epoxy chiral building block derived from inexpensive and readily available D-glucolactone.