It has been known that enterohepatic circulation of bile acids is essential for regular cycling of migrating motor complex (MMC). An important component of the enterohepatic circulation is the active reabsorption of...It has been known that enterohepatic circulation of bile acids is essential for regular cycling of migrating motor complex (MMC). An important component of the enterohepatic circulation is the active reabsorption of conjugated bile acids in the terminal ileum, with special reference to bile acid pool size that may be defined as the total mass of bile acids in the enterohepatic circulation. However, because of technical difficulties in measuring of bile acid pool size in human being, the role of the bile acid pool has little been investigated, and the exact mechanism of change in bile acid pool size has not yet been clear. Therefore, were there two changes of small intestinal motility and bile acid pool size in cholesterol gallstone patients? and, if so, was there correlated relationship between both alterations require further investigation?展开更多
文摘It has been known that enterohepatic circulation of bile acids is essential for regular cycling of migrating motor complex (MMC). An important component of the enterohepatic circulation is the active reabsorption of conjugated bile acids in the terminal ileum, with special reference to bile acid pool size that may be defined as the total mass of bile acids in the enterohepatic circulation. However, because of technical difficulties in measuring of bile acid pool size in human being, the role of the bile acid pool has little been investigated, and the exact mechanism of change in bile acid pool size has not yet been clear. Therefore, were there two changes of small intestinal motility and bile acid pool size in cholesterol gallstone patients? and, if so, was there correlated relationship between both alterations require further investigation?
基金The present chapter is written in the context of the project FOIE GRAS,which has received funding from the European Union’s Horizon 2020 Research and Innovation program under the Marie Sklodowska-Curie Grant Agreement No.722619.