BACKGROUND Chondroid syringoma(CS)is a rare tumor of the apocrine or eccrine glands.CS of the lower back is rare,and its clinical manifestations are similar to those of lipoma,which is a common misdiagnosis for this d...BACKGROUND Chondroid syringoma(CS)is a rare tumor of the apocrine or eccrine glands.CS of the lower back is rare,and its clinical manifestations are similar to those of lipoma,which is a common misdiagnosis for this disease.CASE SUMMARY A 39-year-old woman presented with a 2-year history of an asymptomatic subcutaneous mass on the lower back.The lesions increased progressively over time.The patient denied any history.Dermatological examination showed that there was a subcutaneous mass,ranging from 3-4 cm in diameter,with a clear boundary on the lower back.The surface of the skin was smooth without ulceration or scaling.Histopathologic examination was consistent with the diagnosis of CS.CONCLUSION CS is a rare tumor of the apocrine or eccrine glands.It usually presents as a wellcircumscribed and single subcutaneous masses.Histopathology showed the tumor was located in the dermis,with nests,sheets,and cords of basal-like cells,mucin deposition,and chondroid structures.We herein report a case of CS located in the lower back.CS of the lower back is rare,and its clinical manifestations are similar to those of lipoma,for which it is commonly misdiagnosed.展开更多
目的研究皮肤混合瘤(mixed tumor of the skin,MTS)的临床及组织病理特点。方法回顾性归纳分析本院1980-2007年26例MTS的临床病理资料。结果26例患者中23例为大汗腺性MTS,其中8例出现毛囊和/或皮脂腺分化,5例呈软骨样变,8例出现多少不...目的研究皮肤混合瘤(mixed tumor of the skin,MTS)的临床及组织病理特点。方法回顾性归纳分析本院1980-2007年26例MTS的临床病理资料。结果26例患者中23例为大汗腺性MTS,其中8例出现毛囊和/或皮脂腺分化,5例呈软骨样变,8例出现多少不等的脂肪组织,8例出现浆细胞样细胞,并有1例出现明显软骨及骨样化生;另外4例小汗腺性MTS出现透明细胞,26例MTS肿瘤间质成分均有不同程度的黏液样物质沉积。结论MTS可向毛囊和/或皮脂腺分化,间质表现多样化。展开更多
目的探讨皮肤混合瘤(mixed tumor of the skin,MTS)的临床表现、病理特点及治疗、预后。方法回顾性分析西安交通大学第二附属医院2011年11月—2022年7月经组织病理确诊的74例MTS患者的病史、临床特点、病理特征、治疗效果等资料。结果7...目的探讨皮肤混合瘤(mixed tumor of the skin,MTS)的临床表现、病理特点及治疗、预后。方法回顾性分析西安交通大学第二附属医院2011年11月—2022年7月经组织病理确诊的74例MTS患者的病史、临床特点、病理特征、治疗效果等资料。结果74例患者中男45例,女29例,平均发病年龄(44.23±13.74)岁,病程中位数为2(1.0,3.75)年。皮损多位于面部(69例,93.24%),其中以鼻部(14例,18.92%)、口鼻间(17例,22.97%)、面颊部(20例,27.03%)多见,也可见于耳部(3例)、头皮(1例)、背部(1例)。皮损表现为大小0.5~3.0 cm孤立、境界清楚、质韧或中等硬度、肤色或红色的结节丘疹,71例(95.95%)皮损表面光滑,3例皮损表面可见顶针状凹陷。17例(22.97%)病例皮损表面可见毛细血管扩张。组织病理:62例混合瘤位于真皮,1例位于皮下脂肪层,11例未见表皮,瘤体位置不明确。54例境界清楚,其中53例有假包膜,20例境界不清。肿瘤由比例不定的上皮及间质成分组成。根据上皮组织成分,63例向顶泌汗腺分化,11例向外泌汗腺分化。17例患者电话随访疗效时失访,其余57例随访2个月~10年9个月无复发。结论MTS临床较少见,临床易误诊,主要依靠病理学诊断,但其预后较好,多数皮损手术切除后无复发。展开更多
基金Supported by Shenzhen Sanming Project,No.SZSM201812059Shenzhen Key Medical Discipline Construction Fund,No.SZXK040。
文摘BACKGROUND Chondroid syringoma(CS)is a rare tumor of the apocrine or eccrine glands.CS of the lower back is rare,and its clinical manifestations are similar to those of lipoma,which is a common misdiagnosis for this disease.CASE SUMMARY A 39-year-old woman presented with a 2-year history of an asymptomatic subcutaneous mass on the lower back.The lesions increased progressively over time.The patient denied any history.Dermatological examination showed that there was a subcutaneous mass,ranging from 3-4 cm in diameter,with a clear boundary on the lower back.The surface of the skin was smooth without ulceration or scaling.Histopathologic examination was consistent with the diagnosis of CS.CONCLUSION CS is a rare tumor of the apocrine or eccrine glands.It usually presents as a wellcircumscribed and single subcutaneous masses.Histopathology showed the tumor was located in the dermis,with nests,sheets,and cords of basal-like cells,mucin deposition,and chondroid structures.We herein report a case of CS located in the lower back.CS of the lower back is rare,and its clinical manifestations are similar to those of lipoma,for which it is commonly misdiagnosed.
文摘目的研究皮肤混合瘤(mixed tumor of the skin,MTS)的临床及组织病理特点。方法回顾性归纳分析本院1980-2007年26例MTS的临床病理资料。结果26例患者中23例为大汗腺性MTS,其中8例出现毛囊和/或皮脂腺分化,5例呈软骨样变,8例出现多少不等的脂肪组织,8例出现浆细胞样细胞,并有1例出现明显软骨及骨样化生;另外4例小汗腺性MTS出现透明细胞,26例MTS肿瘤间质成分均有不同程度的黏液样物质沉积。结论MTS可向毛囊和/或皮脂腺分化,间质表现多样化。
文摘目的探讨皮肤混合瘤(mixed tumor of the skin,MTS)的临床表现、病理特点及治疗、预后。方法回顾性分析西安交通大学第二附属医院2011年11月—2022年7月经组织病理确诊的74例MTS患者的病史、临床特点、病理特征、治疗效果等资料。结果74例患者中男45例,女29例,平均发病年龄(44.23±13.74)岁,病程中位数为2(1.0,3.75)年。皮损多位于面部(69例,93.24%),其中以鼻部(14例,18.92%)、口鼻间(17例,22.97%)、面颊部(20例,27.03%)多见,也可见于耳部(3例)、头皮(1例)、背部(1例)。皮损表现为大小0.5~3.0 cm孤立、境界清楚、质韧或中等硬度、肤色或红色的结节丘疹,71例(95.95%)皮损表面光滑,3例皮损表面可见顶针状凹陷。17例(22.97%)病例皮损表面可见毛细血管扩张。组织病理:62例混合瘤位于真皮,1例位于皮下脂肪层,11例未见表皮,瘤体位置不明确。54例境界清楚,其中53例有假包膜,20例境界不清。肿瘤由比例不定的上皮及间质成分组成。根据上皮组织成分,63例向顶泌汗腺分化,11例向外泌汗腺分化。17例患者电话随访疗效时失访,其余57例随访2个月~10年9个月无复发。结论MTS临床较少见,临床易误诊,主要依靠病理学诊断,但其预后较好,多数皮损手术切除后无复发。
