Objective:To investigate the association between gastrointestinal heat retention syndrome(GHRS)and adult chronic eczema.Methods:This caseecontrol study compared GHRS/GHRS accompanied by damp-heat syndrome(GHRSDHS)and ...Objective:To investigate the association between gastrointestinal heat retention syndrome(GHRS)and adult chronic eczema.Methods:This caseecontrol study compared GHRS/GHRS accompanied by damp-heat syndrome(GHRSDHS)and other patient characteristics between subjects with(cases)and without chronic eczema(controls)to identify potential factors associated with this condition.Semi-structured questionnaires were used to collect data via face-to-face interviews.Participants were recruited from Dongzhimen Hospital affiliated with Beijing University of Chinese Medicine.A logistic regression analysis was performed on the collected data,and odds ratios(ORs)were calculated.Results:A total of 168 cases and 172 controls were recruited.Among the cases of adult chronic eczema,there were 79 subjects with GHRS and 68 with GHRS-DHS.Sex(P=.02,OR=0.54,95%confidence interval[CI]:0.32-0.91),GHRS(P=.04,OR=1.90,95%CI:1.02-3.51),GHRS-DHS(P<.001,OR=4.89,95%CI:2.36-10.15),high sweet food consumption(P=.04,OR=2.03,95%CI:1.03-3.97),and mental stress(P=.01,OR=2.37,95%CI:1.26-4.47)were each found to be associated with chronic eczema.Furthermore,GHRS had a weak positive correlation with eczema EASI severity as measured by the eczema area and severity index(EASI)(P=003).Conclusion:GHRS/GHRS-DHS may be associated with adult chronic eczema.In the future,prospective cohort studies with larger samples should be conducted to investigate the cause and effect association between GHRS and adult chronic eczema.展开更多
目的:研究壮医脐环穴针刺法对血虚风燥型慢性湿疹患者的临床疗效。方法:将在广西中医药大学第一附属医院壮医门诊就诊的60例慢性湿疹患者随机分为治疗组和对照组,各30例。对照组予甘草酸苷片联合糠酸莫米松乳膏治疗,治疗组予壮医脐环穴...目的:研究壮医脐环穴针刺法对血虚风燥型慢性湿疹患者的临床疗效。方法:将在广西中医药大学第一附属医院壮医门诊就诊的60例慢性湿疹患者随机分为治疗组和对照组,各30例。对照组予甘草酸苷片联合糠酸莫米松乳膏治疗,治疗组予壮医脐环穴针刺法治疗。观察两组患者的湿疹面积及严重度指数评分(Eczema area and severity index,EASI)、视觉模拟评分(Visual Analogue Scale/Score,VAS)、症状积分下降指数(Symptom Score Reduce Index,SSRI)及临床疗效判定。结果:与对照组相比较,治疗后治疗组的EASI评分、VAS评分和SSRI积分更低,差异有统计学意义(t=1.21、3.735、2.182,P<0.05);经秩和检验分析,治疗组总显效率明显高于对照组,差异有统计学意义(Z=2.569,P<0.05)。结论:壮医脐环穴针刺法可明显改善血虚风燥型慢性湿疹患者的临床症状、体征,临床有效。展开更多
基金supported by the Research on Inheritance and Innovation of Experience(Integration of Tao and Shu)of Illustrious Senior Traditional Chinese Medicine Practitioners by adopting Multiple Research Methods(National Key R&D Program of China2018YFC1704100)+2 种基金Research on Methodology System and Paradigms for Mining and Inheriting Illustrious Senior Traditional Chinese Medicine Practitioners’Experience(2018YFC1704101)the National Natural Science Foundation of China(81373769)Fundamental Research Funds for the Central Universities(2018-JYBZZ-XS033).
文摘Objective:To investigate the association between gastrointestinal heat retention syndrome(GHRS)and adult chronic eczema.Methods:This caseecontrol study compared GHRS/GHRS accompanied by damp-heat syndrome(GHRSDHS)and other patient characteristics between subjects with(cases)and without chronic eczema(controls)to identify potential factors associated with this condition.Semi-structured questionnaires were used to collect data via face-to-face interviews.Participants were recruited from Dongzhimen Hospital affiliated with Beijing University of Chinese Medicine.A logistic regression analysis was performed on the collected data,and odds ratios(ORs)were calculated.Results:A total of 168 cases and 172 controls were recruited.Among the cases of adult chronic eczema,there were 79 subjects with GHRS and 68 with GHRS-DHS.Sex(P=.02,OR=0.54,95%confidence interval[CI]:0.32-0.91),GHRS(P=.04,OR=1.90,95%CI:1.02-3.51),GHRS-DHS(P<.001,OR=4.89,95%CI:2.36-10.15),high sweet food consumption(P=.04,OR=2.03,95%CI:1.03-3.97),and mental stress(P=.01,OR=2.37,95%CI:1.26-4.47)were each found to be associated with chronic eczema.Furthermore,GHRS had a weak positive correlation with eczema EASI severity as measured by the eczema area and severity index(EASI)(P=003).Conclusion:GHRS/GHRS-DHS may be associated with adult chronic eczema.In the future,prospective cohort studies with larger samples should be conducted to investigate the cause and effect association between GHRS and adult chronic eczema.
文摘目的:研究壮医脐环穴针刺法对血虚风燥型慢性湿疹患者的临床疗效。方法:将在广西中医药大学第一附属医院壮医门诊就诊的60例慢性湿疹患者随机分为治疗组和对照组,各30例。对照组予甘草酸苷片联合糠酸莫米松乳膏治疗,治疗组予壮医脐环穴针刺法治疗。观察两组患者的湿疹面积及严重度指数评分(Eczema area and severity index,EASI)、视觉模拟评分(Visual Analogue Scale/Score,VAS)、症状积分下降指数(Symptom Score Reduce Index,SSRI)及临床疗效判定。结果:与对照组相比较,治疗后治疗组的EASI评分、VAS评分和SSRI积分更低,差异有统计学意义(t=1.21、3.735、2.182,P<0.05);经秩和检验分析,治疗组总显效率明显高于对照组,差异有统计学意义(Z=2.569,P<0.05)。结论:壮医脐环穴针刺法可明显改善血虚风燥型慢性湿疹患者的临床症状、体征,临床有效。