Effect of Warm Acupuncture on “Dinghui Acupoint” and “Heart Acupoint” in Traditional Mongolian Medicine on Behaviors and Hypothalamic Inflammatory Cytokines in Rats with Chronic Fatigue Syndrome

Objective: To observe the effects of warm acupuncture on “Dinghui Acupoint” and “Heart Acupoint” in Traditional Mongolian Medicine on behavior and hypothalamic inflammatory cytokines IL-1β, IL-6 and IFN-r in Rats with Chronic Fatigue Syndrome. Methods: SD rats were randomly divided into normal group, model group, warm acupuncture group and moxibustion positive control group. The latter three groups of rats were used to establish a model of rats with chronic fatigue syndrome (CFS) using a combination of physical fatigue and mental fatigue. When establishing the model of warm acupuncture group,“Dinghui Acupoint” and “Heart Acupoint” intervention was carried out;when establishing the model of moxibustion positive control group,“Zusanli Acupoint” intervention was carried out on both sides. Behavioral observations (body weight, exhaustive swimming time, tail suspension experiment, water maze) were performed before and after modeling. The hypothalamic inflammatory cytokines IL-1β, IL-6 and IFN-r were detected by ELISA method after warm acupuncture and moxibustion intervention. Results: After 21 days of modeling, the body weight of the rats in each group was significantly lower than that in the normal group, and there was a significant difference (P<0.01);Compared with the model group, the weight of the rats in the warm acupuncture group increased significantly, and there was a significant difference (P<0.01);Compared with the model group, the exhaustive swimming time of the rats in the warm acupuncture group was significantly prolonged, and there was a significant difference (P<0.01);Compared with the moxibustion group, the exhaustion time of the rats in the warm acupuncture group was relatively prolonged, and there was a significant difference (P<0.05);Compared with the normal group, the tail suspension time of the model group was significantly prolonged, and there was a significant difference (P<0.05);Compared with the model group, there was a significant difference in the duration of the suspension of the warm acupuncture group and the moxibustion group (P<0.01);Compared with the normal group, the total distance of the water maze test was shorter in the model group, and there was a significant difference (P<0.01);Compared with the model group, both the warm acupuncture group and the moxibustion group were prolonged, and there was a significant difference (P<0.05);Compared with the moxibustion group, the distance between the rats in the warm acupuncture group was relatively longer, but there was no significant difference (P>0.05);Compared with the normal group, IL-1β, IL-6 and IFN-r increased significantly in the model group and there was a significant difference (P<0.05);Compared with the model group, IL- 1β and IL-6 in the warm acupuncture group was significantly decreased (P<0.05), and the IL-6 in the moxibustion group was significantly different (P<0.05);Compared with the model group, there was no significant difference between the IFN-r group and the moxibustion group (P>0.05);Compared with the moxibustion group, the levels of IL-1β, IL-6 and IFN-r were not significantly different (P>0.05). Conclusion: Warm acupuncture on “Dinghui Acupoint” and “Heart Acupoint” in Traditional Mongolian Medicine has the ability to improve the body’s defense and self-healing ability, improve chronic fatigue syndrome (CFS), and thus play a preventive role. The results of this research indicate that the warm acupuncture group and the moxibustion group have the same effect.

TREATMENT OF TEN CASES OF CHRONIC FATIGUE SYNDROME WITH CHINESE HERBS,ACUPUNCTURE, AND DIET PRECAUTIONS

Ten cases of chronic fatigue syndrome (CFS) were treated for 4 weeks by acupuncture, Chinese herbs and diet precautions. Diagnosis of CFS was determined by conventional medicine criteria(CDC criteria for CFS), physical examination, and routine laboratory tests. TCM diagnosis of CFS relied on Four Examination Methods and Eight Principal Patterns. They were diagnosed as Ganyu Qizhi (liver and qi stagnation) and Pixu Qiruo (spleen and qi deficiency). The treatment method is to disperse the liver and facilitate qi, rehabilitate the spleen and strengthen qi (Shugan Liqi, Jianpi Yiqi). The result of the treatment indicated that the total effective rate was 100% in terms of fatigue, difficulty concentrating, headache, sore throat, muscle pain, joint aches, feverishness, rapid pulse, insomnia, depression, irregular menses, abdominal cramps, and night sweats. The percentages of specific symptoms of CFS in the patients were comparable to the conventional medical record (Table 1).

Clinical Observation on the Effects of Bo’s Abdominal Acupuncture in 40 Cases of Chronic Fatigue Syndrome

Objective: To observe the curative effect of Bo’s abdominal acupuncture on chronic fatigue syndrome (CFS). Methods: Forty cases with CFS were treated by Bo’s abdominal acupuncture at the points for conducting qi back to its origin and 4 points on the abdomen once a day for 2 weeks. Scores for symptoms and scores for fatigue questionnaires were compared before and after treatment. Results: After treatment, the clinical symptoms of patients were differently alleviated, and scores for symptoms, mental condition and neural feeling in questionnaires on fatigue were obviously reduced (P<0.01-0.05). Conclusion: Bo’s abdominal acupuncture has a good curative effect on general disease with complex symptoms, especially on lassitude, anorexia, insomnia, amnesia, diarrhea, and general pain.

Clinical Observation on Treatment of Chronic Fatigue Syndrome by Combined Acupuncture and Cupping

Objective： To observe the clinical therapeutic effect of needling the acupoints of Governor Vessel and Bladder Meridian plus cupping on chronic fatigue syndrome. Methods： Fifty cases of chronic fatigue syndrome were divided into the treatment group（n= 25） and the control group（n= 25）. The patients in the treatment group were treated by needling Dazhui （GV 14）, Zhiyang （GV 9）, Xinshu （BL 15）, Geshu （BL 17）, Mingmen （GV 4）, Shenshu （BL 23） and Changqiang （GV 1）. Even reinforcing and reducing manipulation was used. Every time after the needles were withdrawn, the glass jar with thick and smooth mouth was selected to go on the back. The patients in the control group were treated by taking Chinese medicinal herbs, Caili composition, orally. Results： After 3 durations of treatment, the therapeutic effects of the two groups were 92. 0% and 64.0% respectively. There was significant difference in the therapeutic effect between the two groups（x^2 = 7.29,P 〈 0.05）.Conclusion： Acupuncture plus cupping is an effective method in treating chronic fatigue syndrome.

Clinical Observation on Acupuncture Therapy for Chronic Fatigue Syndrome

Objective： To observe the clinical effect of acupuncture in treating chronic fatigue syndrome and its effect on anxiety. Methods： Ninety patients who accord with the inclusion criteria were divided into 2 groups, 45 patients in the treatment group received acupuncture therapy, and 45 patients in the control group received medicine therapy. The anxiety state was evaluated with Self-rating Anxiety Scale （SAS） before and after treatments in the two groups. Results： SAS scores of the CFS patients in the two groups decreased after treatment （P〈0.01）. There was no statistical difference of the SAS score between the two groups （P〉0.05）. Conclusion： Both acupuncture and medicine treatments could improve the anxiety symptoms of CFS patient.

Randomized controlled study on acupuncture treatment for chronic fatigue syndrome

Objective To observe the therapeutic effect of acupuncture treatment for chronic fatigue syndrome （CFS）. Methods Ninety cases of CFS were randomly divided into an observation group and a control group, 45 cases in each group. The observation group was treated with acupuncture at Renying （人迎 ST 9）, Fengfu（风府 GV 16）, Batihui （百会 GV 20）; the control group was treated with 250 mL 5% Glucose injeetio combined with 20 mL Shenmai injectio （参脉注射液）. Fatigue Scale （FS） was used to compare the scores between the two groups after treatment. Results The total scores in the observation group ,were 9.37±2.33 and 5.41±1.96 before and after treatment respectively, and in the control group, they were 9.08±2.27 and 7.34±2.03 respectively. FS brainwork integral, physical fatigue integral, and total integral all decreased after treatment in two groups （all P〈0.001）, and it decreased much more obviously in the observation group （P〈0.05, P〈0.01）. Conclusion Both of the acupuncture treatment and Shenmai injectio are able to decrease Fatigue Scale score, improve the fatigue symptoms of CFS patients, and the effect of acupuncture treatment is obviously superior to that of Shenmai injectio.

Tuina plus Acupuncture for Chronic Fatigue Syndrome:A Report of 87 Cases

Officially defined by the US Centers for DiseaseControl and Prevention(CDC),Chronic FatigueSyndrome(CFS)is mainly characterized by apersistent or intermittent fatigue and can greatlyendanger human health.The author treated 87 CFScases in the past two years with tuina plusacupuncture.The report is now as follows.

Acupuncture on back-shu points of five zang for chronic fatigue syndrome:A randomized control trial

Objective: To observe the clinical efficacy of acupuncture on back-shu points of five zang in treating chronic fatigue syndrome(CFS).Methods: Sixty patients were randomized into treatment group and control group. In treatment group,the back-shu points of five zang organs were adopted for acupuncture. Shènshū(肾俞 BL23) was perpendicularly needled 15-30 mm in depth. The rest of the selected points were inserted obliquely 15-30 mm in the direction of the spine with even method of lifting-thrusting and twisting-twirling, 10 s for each acupoint. In control group, the acupoints were approximately 1.5-2 cm away outward from the back-shu points of five zang organs(about on the middle of the two sidelines of the bladder meridian of foottaiyang) and the points from the bladder meridian of foot-taiyang were excluded. Acupoints were needled6-9 mm in depth, and deqi was not required, without any manipulation. The treatments were carried out twice a week for twenty minutes each time, a total of eight treatments were given. The clinical efficacy of acupuncture treatment for CFS was evaluated through the Fatigue Scale-14(FS-14) and the Symptom Check-List 90(SCL-90) after treatment.Results: The total effective rate was 86.67% in the treatment group and 53.33% in the control group(P<0.01). In treatment group, FS-14 total scores, somatic fatigue scores, and mental fatigue scores were significantly reduced than before treatment(all P<0.01). In control group, FS-14 total scores and somatic fatigue scores were significantly reduced(both P<0.01). The improvement of FS-14 total scores, somatic fatigue scores, and mental fatigue scores in the treatment group were better than those in the control group(P<0.01, P<0.05). After treatment, SCL-90 total scores and somatization, compulsion, interpersonal sensitivity, depression, anxiety, hostility, psychoticism, and other factors scores were significantly reduced in the treatment group compared with before treatment(P<0.01). In control group, the SCL-90 total scores and the scores of somatization, compulsion, hostility, and other factors after treatment were lower than those before treatment(P< 0.01). The total scores of SCL-90 and somatization, compulsion, interpersonal sensitivity, depression, anxiety, psychoticism, and other factors in the treatment group were significantly lower than those in the control group(P< 0.01, P< 0.05).Conclusions: Acupuncture on back-shu points of five zang can significantly improve the somatic fatigue and mental fatigue of the patients, and at the same time improve their psychological status. Significant therapeutic effect was found on CFS. Compared with the control group, the acupuncture treatment can significantly improve the patient’s somatic fatigue, mental fatigue and psychological status.

Acupuncture for Chronic Fatigue Syndrome:An Overview of Systematic Reviews

Objective To evaluate the quality of the existing studies and summarize evidence of important outcomes of meta-analyses/systematic reviews(MAs/SRs)of CFS.Methods Potentially eligible studies were searched in the following electronic databases from inception to 1 September,2019:Chinese Biomedical Literature Database(CBM),China Science and Technology Journal Database(VIP),China National Knowledge Infrastructure(CNKI),WanFang Database(WF),Web of Science,Embase,PubMed and Cochrane Library.Grades of Recommendation,Assessment,Development,and Evaluation(GRADE)was used to evaluate the quality of evidence.The methodological quality of the literature was evaluated by A Measure Tool to Assess Systematic Reviews-2(AMSTAR-2)and the quality of the report was assessed by Preferred Reporting Items for Systematic Reviews and Meta-analyses(PRISMA).The intra-class correlation coefficient was used to assess the consistency of the reviewers,with an overall intraclass correlation coefficient score of 0.967.Results Ten MAs/SRs were included.The overall conclusions were that acupuncture had good safety and efficacy in the treatment of CFS,but some of these results were contradictory.The GRADE indicated that out of the 17 outcomes,high-quality evidence was provided in 0(0%),moderate in 3(17.65%),low in 10(58.82%),and very low in 4(23.53%).The results of AMSTAR-2 showed that the methodological quality of all included studies was critically low.The PRISMA statement revealed that 8 articles(80%)were in line with 20 of the 27-item checklist,and 2 articles(20%)matched with 10-19 of the 27 items.Conclusion We found that acupuncture on treating CFS has the advantage for efficacy and safety,but the quality of SRs/MAs of acupuncture for CFS need to be improved.

Clinical Study on Electroacupuncture plus Interferential Current Therapy for Chronic Fatigue Syndrome

Objective: To observe the clinical efficacy of electroacupuncture plus interferential current therapy(ICT) in treating chronic fatigue syndrome(CFS), and to explore the mechanism. Methods: Sixty eligible CFS patients were randomized into a treatment group and a control group, 30 in each group. The treatment group was intervened by electroacupuncture plus ICT, while the control group was by electroacupuncture alone. The therapeutic efficacies were evaluated after 2 treatment courses and compared between the two groups. Results: The recovery rate and total effective rate were respectively 43.3% and 93.3% in the treatment group, versus 20.0% and 80.0% in the control group. There were significant differences in comparing the recovery rate and total effective rate between the two groups(P<0.05), showing that the recovery rate and total effective rate in the treatment group were higher than those in the control group. Conclusion: Electroacupuncture plus ICT can produce a remarkable efficacy in treating CFS.

Treatment of 22 Cases of Chronic Fatigue Syndrome by Puncturing Back-Shu Points

Objective： To observe the clinical effect of puncturing Back-Shu points in treating chronic fatigue syndrome. Methods： Twenty-two subjects were recruited and treated by puncturing corresponding Back-Shu points based on syndrome differentiation. The short-form General Health Survey （MOSSF GHS） and the Chalder Questionnaires for Fatigue were adopted for evaluating the therapeutic effects. Results： Of the 22 patients, 4 cases showed a marked effect, 11 got effect, 7 got failure, and the total effective rate was 68.2%. Conclusion： Puncturing Back-Shu points is effective in relieving the symptoms of chronic fatigue syndrome and enhancing the patients＇ health standard.

Chronic fatigue syndrome treated by the traditional Chinese proce-dure abdominal tuina:a randomized controlled clinical trial

OBJECTIVE: To evaluate the effect of the traditional Chinese procedure abdominal Tuina(AT) on chronic fatigue syndrome(CFS).METHODS: This randomized, single assessor-blinded clinical trial was carried out from May 2014 to April 2015. Eighty participants in the trial were divided randomly into two groups: experimental group and control. The experimental group(40 cases) was treated by AT and the control group(40 cases) by acupuncture. Each treatment was conducted once a day, 5 d for one course, at an interval of 2 d between each course. The whole treatment course lasted for 4 weeks. To ascertain the effect of AT and acupuncture, Fatigue Scale-14(FS-14), Self-rating Anxiety Scale(SAS) and Hamilton Rating Scale for Depression(HAMD) scores were used before and after treatment. Patients were followed up for3 months after treatment.RESULTS: After treatment for 4 weeks, 77 patients(39 cases in the experimental group and 38 cases in the control group) completed the trial. The FS-14,SAS and HAMD scores decreased(P < 0.05) significantly compared with those before treatment in both groups. The FS-14 and HAMD(P < 0.05) scores in the experimental group were much lower than those in the control group. The difference in SAS scores between the two groups was not significant.In the final follow-up, CFS in two cases in the experimental group and three in the control group recurred, but the difference was not significant. The scores for the FS-14, SAS and HAMD in the experimental group were superior to those of the control group, and the difference was significant(P < 0.05).No serious adverse events and few adverse events were observed.CONCLUSION: AT elicited a more efficacious effect than acupuncture alone on CFS.

Clinical observation of abdominal acupuncture for subhealth insomnia

Objective： To assess the clinical efficacy of abdominal acupuncture for subhealth insomnia. Methods： Eighty-two cases of subhealth insomnia were randomly divided into an observation group （41 cases） and a control group （41 cases）. The control group was treated with conventional acupuncture. The observation group was treated with Bo＇s abdominal acupuncture on the basis of conventional acupuncture. Six treatments constituted one treatment course. The measuring scale of traditional Chinese medicine syndrome for subhealth state （MSSSHS） and Pittsburgh sleep quality index （PSQI） scores were compared between the two groups after two courses, to estimate the efficacy of abdominal acupuncture for subhealth insomnia. Results： One case dropped out from the observation group, while 2 cases dropped out from the control group. The MSSSHS score and PSQI score both declined after the treatment in the two groups （all P〈0.05）. The MSSSHS and PSQI scores in the observation group were significantly lower than those in the control group （both P〈0.05）. Conclusion： The abdominal acupuncture is effective for subhealth insomnia, and it can enhance the effect of conventional acupuncture.

温针灸干预慢性疲劳综合征大鼠骨骼肌PINK1/Parkin通路的变化

背景:研究发现慢性疲劳综合征患者线粒体的功能异常,给予辅酶后可改善症状,温针灸是治疗该病的重要方法之一,但其作用机制尚不明确。目的:采用温针灸干预慢性疲劳综合征大鼠骨骼肌PINK1/Parkin通路,明确温针灸对慢性疲劳综合征的治疗机制。方法:将32只雄性SD大鼠适应性喂养3 d后随机分为正常组、模型组、温针灸组和辅酶组,每组各8只,除正常组外,其余各组大鼠以游泳力竭、慢性束缚及禁食多因素方法制备慢性疲劳综合征模型。造模成功后正常组、模型组大鼠采取相同固定及灌胃操作,温针灸组大鼠选用关元、中脘、足三里(双)穴进行治疗,1次/d,进针后将艾柱置于针柄点燃,每次治疗3壮,共15 min;辅酶组按照1 mg/kg进行灌胃,1次/d,共治疗14 d。记录实验期间各组大鼠体质量、力竭游泳时间及治疗期间的食物利用率。治疗结束后,取各组大鼠双侧腓肠肌,苏木精-伊红染色法观察各组大鼠腓肠肌病理形态,透射电镜观察各组大鼠腓肠肌线粒体形态结构及自噬体,免疫组化法检测各组大鼠骨骼肌中微管相关蛋白1轻链3(microtubule associated protein 1 light chain 3,LC3)Ⅱ蛋白表达水平,Western blot法检测各组骨骼肌中PINK1、Parkin、LC3蛋白的表达。结果与结论:①与正常组相比,模型组腓肠肌细胞核固缩、凝聚,数目增多,细胞排列紊乱,腓肠肌纤维排列紧密;温针灸组和辅酶组腓肠肌纤维排列间隙较模型组增加,细胞核减少,细胞排列较模型组整齐。②与正常组比较,模型组骨骼肌线粒体肿胀、融合及空泡化,线粒体膜断裂,基质较多溶解,嵴断裂、消失;存在自噬现象。与模型组比较,温针灸组及辅酶组线粒体数量增多,排列相对整齐,线粒体空泡化及线粒体嵴断裂情况改善,膜结构相对完整;存在自噬现象。③与正常组相比,模型组骨骼肌中PINK1蛋白表达上调(P<0.05)、而Parkin、LC3Ⅱ、LC3Ⅱ/Ⅰ蛋白的表达稍有上调(P>0.05);与模型组相比,温针灸组和辅酶组骨骼肌中PINK1、Parkin、LC3Ⅱ、LC3Ⅱ/Ⅰ蛋白表达明显上调(P<0.05),温针灸组蛋白表达上调更为显著。④结果说明,温针灸可能通过激活PINK1/Parkin通路,上调LC3Ⅱ表达,形成线粒体自噬体,促进降解受损线粒体的相关内容物,改善线粒体质量,从而发挥治疗慢性疲劳综合征的作用。

符文彬从心胆论治慢性疲劳综合征临床经验

符文彬教授根据多年临床经验提出从心胆论治慢性疲劳综合征(CFS),运用“一针二灸三巩固”的针灸治疗方法,整合针刺、精灸、皮内针等针灸适宜技术,选取手太阴心经及足少阳胆经相关腧穴施治,可有效缓解CFS患者疲乏、疼痛及情绪障碍等躯体及心理相关症状。

基于“调神”理论针刺治疗慢性疲劳综合征的临床疗效及对外周血辅助性T细胞1/辅助性T细胞2平衡的影响

目的观察基于“调神”理论指导的针刺治疗慢性疲劳综合征(CFS)患者的疗效及对外周血辅助性T细胞1(Th1)/Th2平衡的影响。方法将90例CFS患者按照随机数字表法分为2组,对照组45例予常规针刺法进行治疗,治疗组45例采用基于“调神”理论指导的针刺法治疗。2组均治疗4周。比较2组治疗前后疲劳量表-14(FS-14)、疲劳评定量表(FAI)、汉密尔顿焦虑量表(HAMA)评分及血清干扰素γ(IFN-γ)、白细胞介素4(IL-4)水平,并统计2组总有效率。结果治疗组总有效率93.33%(42/45),对照组总有效率77.78%(35/45),治疗组临床疗效优于对照组(P<0.05)。2组治疗后FS-14躯体疲劳评分、脑力疲劳评分及总分均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。2组治疗后FAI、HAMA评分均较本组治疗前降低(P<0.05),且治疗组治疗后均低于对照组(P<0.05)。2组治疗后血清IFN-γ水平及IFN-γ/IL-4均较本组治疗前升高(P<0.05),且治疗组治疗后均高于对照组(P<0.05),2组治疗后IL-4水平均降低(P<0.05),且治疗组治疗后低于对照组(P<0.05)。结论基于“调神”理论指导的针刺治疗CFS患者疗效显著,能够改善患者疲劳、焦虑状态,促进Th1/Th2平衡。

不同针灸方法对慢性疲劳综合征大鼠运动能力及细胞因子的影响

目的:探讨不同针灸方法对慢性疲劳综合征(CFS)大鼠运动能力及细胞因子的影响。方法:64只SD大鼠随机分为空白对照组、模型组、毫针1组、毫针2组、电针1组、电针2组、艾灸1组、艾灸2组,每组8只。采用慢性多重复合应激法制备CFS大鼠模型。毫针1组、电针1组、艾灸1组选取百会、足三里(双)、三阴交(双)穴,分别采用毫针、电针、艾灸治疗,每天1次,连续治疗18 d。毫针2组、电针2组、艾灸2组操作同1组,隔天1次,连续治疗9次。治疗结束后,记录大鼠负重力竭游泳时间以测评大鼠运动能力,检测大鼠血清IL-4、IL-10、IFN-γ、TNF-α分泌水平。结果:造模完成后,模型组大鼠力竭游泳时间较空白对照组缩短(P<0.05),针灸各组治疗后大鼠力竭游泳时间均较模型组长(P<0.05),其中艾灸1组大鼠力竭游泳时间最长;模型组大鼠血清IL-4、IL-10水平较空白对照组升高,IFN-γ、TNF-α水平较空白对照组降低。针灸治疗后,各组IL-4、IL-10水平均下降,IFN-γ、TNF-α水平均上升,其中艾灸1组对IL-4、IL-10的改善优于其他治疗组。结论:毫针、电针、艾灸均可延长大鼠力竭游泳时间,调节细胞因子的分泌水平,以艾灸每日1次的效果为最佳。

虎符铜砭刮痧配合西药治疗慢性非萎缩性胃炎(肝胃不和型)30例疗效观察

目的:观察虎符铜砭刮痧干预慢性非萎缩性胃炎(肝胃不和证)的临床疗效。方法:60例中医辨证属肝胃不和证慢性非萎缩性胃炎患者,按就诊顺序分为观察组和对照组,每组30例。两组均采用西医常规治疗,奥美拉唑肠溶胶囊20 mg,1次/d,枸橼酸莫沙必利5 mg,3次/d。观察组在常规治疗的基础上加用虎符铜砭刮痧治疗,每周治疗1次,两组均治疗4周。观察两组治疗前后胃脘胀痛、两胁胀满、嗳气、嘈杂反酸、善太息中医证候积分变化,并比较临床疗效。结果:观察组临床有效率为100%,对照组临床有效率为96.7%,观察组疗效优于对照组(P<0.01);两组各项中医证候积分方面差异均具有统计学意义,观察组优于对照组(P<0.01)。结论:西医常规治疗联合虎符铜砭刮痧,较单纯口服药物治疗效果显著。

基于经络理论探析针灸治疗慢性疲劳综合征的思路

慢性疲劳综合征(Chronic Fatigue Syndrome, CFS)患病率呈逐年上涨趋势,严重影响患者生活质量,目前尚未出现针对性的治疗手段。中医常采用中药、针灸、推拿等方法治疗CFS,其中针灸治疗CFS疗效显著且易于推广。经络具有联络脏腑,网络全身,有运行气血,协调阴阳等作用,从经络入手呼应了中医整体观念和辨证论治的原则,有利于从整体上把握CFS的治则治法。因而可基于经络理论、经络与脏腑关系探析CFS的病因病机、临床治疗思路,总结归纳目前的临床进展中分经辨证、分经选穴、针灸施治的实例,从而在经络辨证的角度上进一步拓展针灸治疗CFS的思路。

中医外治法治疗慢性疲劳综合征临床研究进展

慢性疲劳综合征(CFS)是以长期持久或反复发作的疲劳为主要特征,并伴有乏力、肌肉酸痛、淋巴结肿大、注意力不集中、情绪低落、睡眠障碍等躯体及神经精神症状的一组症候群,呈现广泛性、低龄化的发病趋势。通过对近5年来中医外治法治疗CFS的相关文献进行总结,笔者发现中医外治法治疗CFS已得到广泛应用,针刺、灸法、穴位贴敷、推拿、拔罐及综合疗法等治疗CFS具有操作简便、易于接受、无依赖性等优势,但目前仍存在临床研究开展较少,样本量不足,机制研究较少,缺乏客观指标等问题。