Purpose: To clarify the impact of bone metabolism disorder on lumbago in Parkinson’s Disease (PD). Methods: Data was retrospectively analyzed from 52 patients with PD in our outpatient clinic for more than 1 year (me...Purpose: To clarify the impact of bone metabolism disorder on lumbago in Parkinson’s Disease (PD). Methods: Data was retrospectively analyzed from 52 patients with PD in our outpatient clinic for more than 1 year (mean age, 63 ± 4 years old;mean duration from onset, 6.3 ± 0.8 years). Patients’ characteristics, comorbid musculoskeletal disorders, serum bone metabolism biomarkers, and bone mineral density were examined. Results: Twenty-one PD patients (40.2%) had chronic lumbago. Severe comptocormia and scoliosis were the most common musculosketal disorders in this group (47.6%) affected by lumbago, followed by osteoporosis (14.3%), compression fracture (4.8%). There was no significant difference in the duration of PD, body mass index, frequency of falls, bone mineral density, tartrate-resistant acid phosphatase-5b, osteocalcin, and N-terminal telopeptide between PD patients with or without chronic lumbago. Multivaritae logistic regression analysis identified the independent predictors of chroni lumbago in PD patients as Hoen-Yahr stage (odds ration [OR] = 2.794, 95%CI 1.103 - 7.076), and elevated serum 1,25-OH<sub>2</sub> vitamin D level ([OR] = 0.92, 95%CI 0.86 - 98). Conclusion: Bone metabolism disorders are found to be associated with chronic lumbago in PD patients.展开更多
目的此研究旨在研究局部密集针刺结合筋膜松解干预治疗慢性非特异性腰痛(Chronic nonspecific low back pain,CNLBP)的临床疗效。方法将60例CNLBP患者随机分为观察组(30例)和对照组(30例),对照组采用局部密集针刺治疗,观察组在对照组基...目的此研究旨在研究局部密集针刺结合筋膜松解干预治疗慢性非特异性腰痛(Chronic nonspecific low back pain,CNLBP)的临床疗效。方法将60例CNLBP患者随机分为观察组(30例)和对照组(30例),对照组采用局部密集针刺治疗,观察组在对照组基础上加用筋膜松解干预,采用VAS、ODI及JOA评分评估腰痛患者治疗前后的临床情况。结果治疗后,2组VAS评分和ODI评分降低,JOA评分升高,差异均有统计学意义(P<0.05);且VAS评分、ODI及JOA评分组间对比,差异有统计学意义(P<0.05)。结论局部密集针刺结合筋膜松解干预治疗相对于单纯密集针刺在缓解患者疼痛,提高腰部功能方面效果更好。展开更多
文摘Purpose: To clarify the impact of bone metabolism disorder on lumbago in Parkinson’s Disease (PD). Methods: Data was retrospectively analyzed from 52 patients with PD in our outpatient clinic for more than 1 year (mean age, 63 ± 4 years old;mean duration from onset, 6.3 ± 0.8 years). Patients’ characteristics, comorbid musculoskeletal disorders, serum bone metabolism biomarkers, and bone mineral density were examined. Results: Twenty-one PD patients (40.2%) had chronic lumbago. Severe comptocormia and scoliosis were the most common musculosketal disorders in this group (47.6%) affected by lumbago, followed by osteoporosis (14.3%), compression fracture (4.8%). There was no significant difference in the duration of PD, body mass index, frequency of falls, bone mineral density, tartrate-resistant acid phosphatase-5b, osteocalcin, and N-terminal telopeptide between PD patients with or without chronic lumbago. Multivaritae logistic regression analysis identified the independent predictors of chroni lumbago in PD patients as Hoen-Yahr stage (odds ration [OR] = 2.794, 95%CI 1.103 - 7.076), and elevated serum 1,25-OH<sub>2</sub> vitamin D level ([OR] = 0.92, 95%CI 0.86 - 98). Conclusion: Bone metabolism disorders are found to be associated with chronic lumbago in PD patients.
文摘目的此研究旨在研究局部密集针刺结合筋膜松解干预治疗慢性非特异性腰痛(Chronic nonspecific low back pain,CNLBP)的临床疗效。方法将60例CNLBP患者随机分为观察组(30例)和对照组(30例),对照组采用局部密集针刺治疗,观察组在对照组基础上加用筋膜松解干预,采用VAS、ODI及JOA评分评估腰痛患者治疗前后的临床情况。结果治疗后,2组VAS评分和ODI评分降低,JOA评分升高,差异均有统计学意义(P<0.05);且VAS评分、ODI及JOA评分组间对比,差异有统计学意义(P<0.05)。结论局部密集针刺结合筋膜松解干预治疗相对于单纯密集针刺在缓解患者疼痛,提高腰部功能方面效果更好。
